Monosodium laevo-aspartate

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  • Identifiers

    CAS number
    39557-43-2

    Molecular formula
    C4H6NNaO4

    SMILES
    C(C(C(=O)O)N)C(=O)[O-].[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 81.87%
    Savory 27.19%
    Sweet 25.35%
    Sour 17.74%
    Milky 16.97%
    Buttery 16.17%
    Cooked 16.1%
    Meaty 16.03%
    Caramellic 15.83%
    Clean 15.32%

     

    Flavor
    Odorless 70.85%
    Mild 32.15%
    Very mild 30.44%
    Bland 25.37%
    Sour 23.51%
    Yeast 23.26%
    Faint 21.69%
    Sweet-like 21.6%
    Mousy 19.27%
    Urine 19.26%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.76 (weak acid)

    Molecular weight
    155.08 g/mol

    Flash point

    • 141.3 ˚C est.

  • Synonyms

    • 39557-43-2
    • C4H6NNaO4
    • monosodium laevo-aspartate
    • WTWSHHITWMVLBX-UHFFFAOYSA-M
    • DTXSID701375538
    • Aspartic acid, sodium salt (1:1)
    • sodium;2-amino-4-hydroxy-4-oxo-butanoate
    • DB-221860
    • 39557-43-2

  • Applications

    Monosodium laevo-aspartate (CAS 39557-43-2) is used as a source of L-aspartate and as a building block in amino acid derivative synthesis across several industries. In biotech and pharmaceutical manufacturing, it may serve as a source of L-aspartate for cell culture media or fermentation feeds; as an industrial intermediate it can provide a precursor for further amino acid based derivatives; in formulations and aqueous systems it can function as a buffering or metal-chelating component; in cosmetics and personal care it is evaluated for use as a source of amino acids and as a formulation stabilizing ingredient; and it may be considered for dietary supplement or feed additive applications where allowed by local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.05
    methanol 25.65
    isopropanol 5.87
    water 41.52
    ethyl acetate 1.44
    n-propanol 6.05
    acetone 12.63
    n-butanol 4.2
    acetonitrile 3.69
    DMF 98.09
    toluene 0.91
    isobutanol 3.03
    1,4-dioxane 19.42
    methyl acetate 3.17
    THF 14.84
    2-butanone 3.78
    n-pentanol 2.35
    sec-butanol 3.71
    n-hexane 0.44
    ethylene glycol 35.31
    NMP 45.25
    cyclohexane 0.56
    DMSO 91.34
    n-butyl acetate 1.05
    n-octanol 1.21
    chloroform 0.51
    n-propyl acetate 1.07
    acetic acid 10.26
    dichloromethane 1.16
    cyclohexanone 4.9
    propylene glycol 16.46
    isopropyl acetate 1.0
    DMAc 62.67
    2-ethoxyethanol 21.32
    isopentanol 3.43
    n-heptane 0.44
    ethyl formate 9.24
    1,2-dichloroethane 1.7
    n-hexanol 2.05
    2-methoxyethanol 57.66
    isobutyl acetate 0.39
    tetrachloromethane 0.45
    n-pentyl acetate 0.82
    transcutol 13.1
    n-heptanol 1.6
    ethylbenzene 0.83
    MIBK 1.69
    2-propoxyethanol 10.43
    tert-butanol 9.54
    MTBE 2.82
    2-butoxyethanol 7.02
    propionic acid 3.67
    o-xylene 1.53
    formic acid 57.94
    diethyl ether 2.36
    m-xylene 0.86
    p-xylene 0.99
    chlorobenzene 0.34
    dimethyl carbonate 4.07
    n-octane 0.23
    formamide 58.02
    cyclopentanone 6.98
    2-pentanone 2.92
    anisole 2.62
    cyclopentyl methyl ether 3.6
    gamma-butyrolactone 9.22
    1-methoxy-2-propanol 20.02
    pyridine 3.83
    3-pentanone 1.95
    furfural 17.6
    n-dodecane 0.13
    diethylene glycol 24.38
    diisopropyl ether 0.65
    tert-amyl alcohol 6.3
    acetylacetone 4.55
    n-hexadecane 0.14
    acetophenone 2.6
    methyl propionate 2.44
    isopentyl acetate 0.96
    trichloroethylene 1.21
    n-nonanol 1.24
    cyclohexanol 3.04
    benzyl alcohol 3.48
    2-ethylhexanol 1.15
    isooctanol 1.15
    dipropyl ether 1.47
    1,2-dichlorobenzene 0.46
    ethyl lactate 2.98
    propylene carbonate 3.83
    n-methylformamide 40.29
    2-pentanol 1.97
    n-pentane 0.38
    1-propoxy-2-propanol 5.3
    1-methoxy-2-propyl acetate 2.39
    2-(2-methoxypropoxy) propanol 8.74
    mesitylene 0.78
    ε-caprolactone 4.43
    p-cymene 0.61
    epichlorohydrin 8.1
    1,1,1-trichloroethane 0.49
    2-aminoethanol 29.54
    morpholine-4-carbaldehyde 47.31
    sulfolane 20.26
    2,2,4-trimethylpentane 0.19
    2-methyltetrahydrofuran 5.45
    n-hexyl acetate 1.07
    isooctane 0.12
    2-(2-butoxyethoxy)ethanol 10.12
    sec-butyl acetate 0.58
    tert-butyl acetate 1.65
    decalin 0.27
    glycerin 40.99
    diglyme 21.53
    acrylic acid 5.46
    isopropyl myristate 0.6
    n-butyric acid 3.18
    acetyl acetate 1.15
    di(2-ethylhexyl) phthalate 1.35
    ethyl propionate 1.24
    nitromethane 21.12
    1,2-diethoxyethane 2.45
    benzonitrile 1.31
    trioctyl phosphate 1.0
    1-bromopropane 0.6
    gamma-valerolactone 20.24
    n-decanol 1.06
    triethyl phosphate 1.6
    4-methyl-2-pentanol 1.23
    propionitrile 1.83
    vinylene carbonate 3.98
    1,1,2-trichlorotrifluoroethane 11.22
    DMS 1.45
    cumene 0.71
    2-octanol 0.85
    2-hexanone 1.47
    octyl acetate 0.92
    limonene 0.76
    1,2-dimethoxyethane 35.71
    ethyl orthosilicate 1.44
    tributyl phosphate 1.03
    diacetone alcohol 6.44
    N,N-dimethylaniline 3.65
    acrylonitrile 3.32
    aniline 1.92
    1,3-propanediol 25.67
    bromobenzene 0.26
    dibromomethane 0.7
    1,1,2,2-tetrachloroethane 1.51
    2-methyl-cyclohexyl acetate 1.17
    tetrabutyl urea 2.79
    diisobutyl methanol 0.91
    2-phenylethanol 2.33
    styrene 0.7
    dioctyl adipate 1.18
    dimethyl sulfate 10.87
    ethyl butyrate 1.26
    methyl lactate 7.4
    butyl lactate 2.07
    diethyl carbonate 1.17
    propanediol butyl ether 7.05
    triethyl orthoformate 1.61
    p-tert-butyltoluene 0.61
    methyl 4-tert-butylbenzoate 3.72
    morpholine 19.79
    tert-butylamine 3.56
    n-dodecanol 0.86
    dimethoxymethane 27.49
    ethylene carbonate 3.17
    cyrene 11.8
    2-ethoxyethyl acetate 1.5
    2-ethylhexyl acetate 0.67
    1,2,4-trichlorobenzene 0.61
    4-methylpyridine 3.8
    dibutyl ether 0.85
    2,6-dimethyl-4-heptanol 0.91
    DEF 10.6
    dimethyl isosorbide 10.81
    tetrachloroethylene 1.54
    eugenol 5.59
    triacetin 1.86
    span 80 4.86
    1,4-butanediol 10.27
    1,1-dichloroethane 0.56
    2-methyl-1-pentanol 2.15
    methyl formate 38.05
    2-methyl-1-butanol 3.03
    n-decane 0.2
    butyronitrile 1.8
    3,7-dimethyl-1-octanol 0.98
    1-chlorooctane 0.35
    1-chlorotetradecane 0.22
    n-nonane 0.21
    undecane 0.16
    tert-butylcyclohexane 0.19
    cyclooctane 0.33
    cyclopentanol 4.47
    tetrahydropyran 4.27
    tert-amyl methyl ether 2.74
    2,5,8-trioxanonane 18.8
    1-hexene 0.65
    2-isopropoxyethanol 7.66
    2,2,2-trifluoroethanol 9.17
    methyl butyrate 2.45

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction