Monosodium Glucuronate

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  • Identifiers

    CAS number
    14984-34-0

    Molecular formula
    C6H9NaO7

    SMILES
    C(=O)[C@@H]([C@H]([C@@H]([C@@H](C(=O)[O-])O)O)O)O.[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 73.23%
    Sweet 35.51%
    Caramellic 30.84%
    Buttery 23.47%
    Savory 19.53%
    Milky 17.6%
    Burnt 16.67%
    Sharp 16.44%
    Bitter 15.82%
    Clean 15.74%

     

    Flavor
    Odorless 64.25%
    Very mild 33.24%
    Sweet-like 26.51%
    Bland 23.2%
    Caramellic 21.01%
    Mild 20.27%
    Yeast 20.18%
    Very slight 18.86%
    Acetoin 18.21%
    Formyl 18.01%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    1.0 (strong acid)

    Molecular weight
    216.12 g/mol

    Flash point

    • 208.01 ˚C est.

  • Synonyms

    • Monosodium glucuronate
    • RefChem:887545
    • sodium glucuronate
    • 14984-34-0
    • Sodium D-glucuronate
    • D-GLUCURONIC ACID SODIUM SALT
    • D-Glucuronic acid, sodium salt (1:1)
    • Glucuronate sodium
    • sodium-d-glucuronate
    • Glucuronic acid sodium
    • sodium;(2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate
    • 631391W27S
    • SODIUM (2S,3S,4S,5R)-2,3,4,5-TETRAHYDROXY-6-OXOHEXANOATE
    • C6H9NaO7
    • Glucuronic acid, monosodium salt
    • MS04198
    • D-Glucuronic acid, sodium salt monohydrate
    • Sodium glucuronate [JAN]
    • UNII-631391W27S
    • EINECS 239-065-7
    • Glucuronic acid (sodium)
    • SCHEMBL74249
    • Sodium-D-glucuronate monohydrate
    • CHEMBL2104556
    • CHEBI:32144
    • DTXSID40933767
    • SODIUM GLUCURONATE [MART.]
    • D-Glucuronic acid sodium monohydrate
    • GLUCURONIC ACID SODIUM [WHO-DD]
    • AS-80404
    • MG175420
    • CS-1232274
    • NS00014055
    • NS00085703
    • F87131
    • G-3621
    • Q27114799
    • sodium;(2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxo-hexanoate
    • rel-Sodium (2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate
    • Sodium (2S,3S,4S,5R)-rel-2,3,4,5-tetrahydroxy-6-oxohexanoate
    • 14984-34-0

  • Applications

    Monosodium Glucuronate (CAS 14984-34-0) is used primarily as an intermediate in the synthesis of glucuronide derivatives for pharmaceutical and chemical applications. It also functions as a chelating/sequestering agent in cleaning formulations and industrial processes, helping to bind metal ions. In addition, it can act as a stabilizer and buffering component in polymer, coatings, and ink formulations. It may be employed as a processing aid and formulation component in cosmetics and personal care products, and as a precursor or formulation aid in agrochemical and pharmaceutical excipient manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 23.91
    methanol 106.06
    isopropanol 9.02
    water 983.27
    ethyl acetate 2.0
    n-propanol 10.35
    acetone 8.27
    n-butanol 5.84
    acetonitrile 3.12
    DMF 364.74
    toluene 0.92
    isobutanol 4.09
    1,4-dioxane 14.58
    methyl acetate 2.7
    THF 9.99
    2-butanone 4.2
    n-pentanol 2.24
    sec-butanol 6.38
    n-hexane 0.22
    ethylene glycol 319.67
    NMP 214.58
    cyclohexane 1.81
    DMSO 1105.4
    n-butyl acetate 1.0
    n-octanol 1.68
    chloroform 0.31
    n-propyl acetate 0.83
    acetic acid 23.35
    dichloromethane 0.77
    cyclohexanone 7.0
    propylene glycol 93.6
    isopropyl acetate 1.32
    DMAc 178.9
    2-ethoxyethanol 35.91
    isopentanol 3.48
    n-heptane 1.22
    ethyl formate 2.85
    1,2-dichloroethane 1.67
    n-hexanol 3.04
    2-methoxyethanol 141.86
    isobutyl acetate 0.25
    tetrachloromethane 0.32
    n-pentyl acetate 0.78
    transcutol 22.82
    n-heptanol 2.4
    ethylbenzene 0.5
    MIBK 1.88
    2-propoxyethanol 17.8
    tert-butanol 9.95
    MTBE 2.08
    2-butoxyethanol 8.77
    propionic acid 11.85
    o-xylene 1.98
    formic acid 388.17
    diethyl ether 2.71
    m-xylene 1.17
    p-xylene 0.48
    chlorobenzene 0.23
    dimethyl carbonate 9.0
    n-octane 0.45
    formamide 371.88
    cyclopentanone 9.39
    2-pentanone 3.74
    anisole 1.34
    cyclopentyl methyl ether 5.56
    gamma-butyrolactone 13.82
    1-methoxy-2-propanol 53.67
    pyridine 4.13
    3-pentanone 3.64
    furfural 14.93
    n-dodecane 0.23
    diethylene glycol 64.48
    diisopropyl ether 0.96
    tert-amyl alcohol 7.45
    acetylacetone 6.39
    n-hexadecane 0.25
    acetophenone 2.21
    methyl propionate 6.43
    isopentyl acetate 0.71
    trichloroethylene 1.19
    n-nonanol 1.61
    cyclohexanol 8.36
    benzyl alcohol 3.05
    2-ethylhexanol 1.48
    isooctanol 1.5
    dipropyl ether 2.56
    1,2-dichlorobenzene 0.35
    ethyl lactate 4.76
    propylene carbonate 3.37
    n-methylformamide 114.08
    2-pentanol 3.63
    n-pentane 0.59
    1-propoxy-2-propanol 9.41
    1-methoxy-2-propyl acetate 3.87
    2-(2-methoxypropoxy) propanol 8.48
    mesitylene 1.13
    ε-caprolactone 6.19
    p-cymene 0.89
    epichlorohydrin 6.28
    1,1,1-trichloroethane 0.3
    2-aminoethanol 152.45
    morpholine-4-carbaldehyde 111.73
    sulfolane 82.92
    2,2,4-trimethylpentane 0.3
    2-methyltetrahydrofuran 4.78
    n-hexyl acetate 0.96
    isooctane 0.16
    2-(2-butoxyethoxy)ethanol 11.75
    sec-butyl acetate 0.48
    tert-butyl acetate 1.79
    decalin 0.33
    glycerin 273.98
    diglyme 20.57
    acrylic acid 22.06
    isopropyl myristate 0.55
    n-butyric acid 5.17
    acetyl acetate 1.37
    di(2-ethylhexyl) phthalate 0.87
    ethyl propionate 1.29
    nitromethane 33.75
    1,2-diethoxyethane 2.28
    benzonitrile 0.76
    trioctyl phosphate 0.98
    1-bromopropane 0.58
    gamma-valerolactone 26.83
    n-decanol 1.32
    triethyl phosphate 1.53
    4-methyl-2-pentanol 1.62
    propionitrile 1.74
    vinylene carbonate 3.33
    1,1,2-trichlorotrifluoroethane 27.64
    DMS 1.95
    cumene 0.42
    2-octanol 1.25
    2-hexanone 0.98
    octyl acetate 0.85
    limonene 1.61
    1,2-dimethoxyethane 17.64
    ethyl orthosilicate 1.33
    tributyl phosphate 0.74
    diacetone alcohol 10.66
    N,N-dimethylaniline 2.54
    acrylonitrile 3.76
    aniline 2.88
    1,3-propanediol 77.31
    bromobenzene 0.18
    dibromomethane 0.52
    1,1,2,2-tetrachloroethane 1.74
    2-methyl-cyclohexyl acetate 1.0
    tetrabutyl urea 2.36
    diisobutyl methanol 1.27
    2-phenylethanol 2.39
    styrene 0.4
    dioctyl adipate 1.02
    dimethyl sulfate 34.72
    ethyl butyrate 1.25
    methyl lactate 26.99
    butyl lactate 2.24
    diethyl carbonate 0.82
    propanediol butyl ether 10.45
    triethyl orthoformate 1.47
    p-tert-butyltoluene 0.99
    methyl 4-tert-butylbenzoate 3.75
    morpholine 25.46
    tert-butylamine 3.39
    n-dodecanol 1.08
    dimethoxymethane 43.72
    ethylene carbonate 2.56
    cyrene 20.39
    2-ethoxyethyl acetate 1.56
    2-ethylhexyl acetate 0.6
    1,2,4-trichlorobenzene 0.54
    4-methylpyridine 2.69
    dibutyl ether 0.78
    2,6-dimethyl-4-heptanol 1.27
    DEF 22.27
    dimethyl isosorbide 10.92
    tetrachloroethylene 1.87
    eugenol 4.2
    triacetin 2.15
    span 80 7.18
    1,4-butanediol 24.84
    1,1-dichloroethane 0.39
    2-methyl-1-pentanol 1.46
    methyl formate 42.33
    2-methyl-1-butanol 3.61
    n-decane 0.37
    butyronitrile 1.09
    3,7-dimethyl-1-octanol 1.01
    1-chlorooctane 0.5
    1-chlorotetradecane 0.27
    n-nonane 0.39
    undecane 0.29
    tert-butylcyclohexane 0.17
    cyclooctane 1.13
    cyclopentanol 9.41
    tetrahydropyran 4.59
    tert-amyl methyl ether 2.9
    2,5,8-trioxanonane 18.41
    1-hexene 0.29
    2-isopropoxyethanol 10.52
    2,2,2-trifluoroethanol 31.96
    methyl butyrate 1.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction