Monoisostearyl glyceryl ether

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  • Identifiers

    CAS number
    78145-84-3

    Molecular formula
    C21H44O3

    SMILES
    CC(C)CCCCCCCCCCCCCCCOCC(CO)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 65.56%
    Fatty 43.17%
    Oily 40.86%
    Odorless 33.05%
    Woody 24.69%
    Fresh 24.63%
    Clean 24.23%
    Fruity 23.76%
    Amber 23.26%
    Sweet 22.53%

     

    Flavor
    Waxy 47.84%
    Mild 39.54%
    Fatty 36.78%
    Oily 32.57%
    Bland 29.91%
    Floral 27.19%
    Fat 26.79%
    Flower 25.43%
    Faint 25.24%
    Soapy 24.84%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.3

    pKa est.
    7.03 (neutral)

    Molecular weight
    344.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    425°C

    Flash point

    • 197.28 ˚C est.

  • Synonyms

    • monoisostearyl glyceryl ether
    • GE-IS cpd
    • RefChem:149991
    • Isostearyl glyceryl ether
    • Penetol GE-IS
    • GE-IS
    • 78145-84-3
    • UNII-OWD43055HV
    • OWD43055HV
    • 1,2-Propanediol, 3-(isooctadecyloxy)-
    • Isostearyl glyceryl ether [INCI]
    • alpha-Monoisostearyl glyceryl ether
    • Glycerol alpha-monoisostearyl ether
    • 3-(16-methylheptadecoxy)propane-1,2-diol
    • SCHEMBL186687
    • 3-[(16-METHYLHEPTADECYL)OXY]PROPANE-1,2-DIOL
    • DTXSID80999387
    • .ALPHA.-MONOISOSTEARYL GLYCERYL ETHER
    • GLYCEROL .ALPHA.-MONOISOSTEARYL ETHER
    • Q27285885
    • 78145-84-3

  • Applications

    Monoisostearyl glyceryl ether (CAS 78145-84-3) is commonly used as a nonionic surfactant and emulsifier in cosmetic and personal care formulations, where it also functions as an emollient and conditioning agent to improve texture and feel. It is also employed in household cleaning products as a surfactant and solubilizer to enhance wetting, dispersion, and formulation stability. In industrial manufacturing, it can act as a processing aid and lubricant for polymers and coatings, aiding melt flow and pigment or additive dispersion. In coatings, inks, and adhesive systems, it can serve as a surfactant or emulsifier to facilitate pigment dispersion and overall performance. It may also be used as a solvent or carrier for active ingredients in various formulations and as a compatibility additive to improve formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.44
    methanol 14.29
    isopropanol 12.1
    water 0.03
    ethyl acetate 61.33
    n-propanol 15.5
    acetone 35.51
    n-butanol 22.62
    acetonitrile 9.84
    DMF 45.72
    toluene 19.83
    isobutanol 18.08
    1,4-dioxane 82.77
    methyl acetate 33.36
    THF 261.06
    2-butanone 51.3
    n-pentanol 21.35
    sec-butanol 21.41
    n-hexane 7.17
    ethylene glycol 1.47
    NMP 153.0
    cyclohexane 43.61
    DMSO 135.4
    n-butyl acetate 111.18
    n-octanol 45.45
    chloroform 173.02
    n-propyl acetate 113.93
    acetic acid 29.49
    dichloromethane 157.4
    cyclohexanone 212.52
    propylene glycol 5.26
    isopropyl acetate 79.95
    DMAc 109.84
    2-ethoxyethanol 62.55
    isopentanol 38.88
    n-heptane 16.96
    ethyl formate 30.06
    1,2-dichloroethane 111.0
    n-hexanol 25.25
    2-methoxyethanol 53.9
    isobutyl acetate 85.78
    tetrachloromethane 52.27
    n-pentyl acetate 182.13
    transcutol 459.99
    n-heptanol 42.54
    ethylbenzene 21.69
    MIBK 88.32
    2-propoxyethanol 65.35
    tert-butanol 40.91
    MTBE 62.73
    2-butoxyethanol 114.89
    propionic acid 25.73
    o-xylene 27.43
    formic acid 6.52
    diethyl ether 36.2
    m-xylene 22.86
    p-xylene 31.47
    chlorobenzene 37.76
    dimethyl carbonate 16.04
    n-octane 7.94
    formamide 11.51
    cyclopentanone 191.49
    2-pentanone 66.33
    anisole 49.21
    cyclopentyl methyl ether 136.93
    gamma-butyrolactone 166.56
    1-methoxy-2-propanol 67.06
    pyridine 56.87
    3-pentanone 54.98
    furfural 124.61
    n-dodecane 3.98
    diethylene glycol 26.93
    diisopropyl ether 29.91
    tert-amyl alcohol 51.13
    acetylacetone 100.72
    n-hexadecane 4.88
    acetophenone 77.79
    methyl propionate 43.09
    isopentyl acetate 129.95
    trichloroethylene 193.8
    n-nonanol 45.93
    cyclohexanol 70.96
    benzyl alcohol 31.52
    2-ethylhexanol 43.45
    isooctanol 53.84
    dipropyl ether 93.17
    1,2-dichlorobenzene 60.21
    ethyl lactate 48.11
    propylene carbonate 109.33
    n-methylformamide 17.08
    2-pentanol 24.21
    n-pentane 4.91
    1-propoxy-2-propanol 100.55
    1-methoxy-2-propyl acetate 117.77
    2-(2-methoxypropoxy) propanol 97.08
    mesitylene 24.29
    ε-caprolactone 193.05
    p-cymene 33.75
    epichlorohydrin 182.7
    1,1,1-trichloroethane 139.36
    2-aminoethanol 6.66
    morpholine-4-carbaldehyde 133.25
    sulfolane 372.15
    2,2,4-trimethylpentane 10.54
    2-methyltetrahydrofuran 167.99
    n-hexyl acetate 153.35
    isooctane 6.32
    2-(2-butoxyethoxy)ethanol 139.07
    sec-butyl acetate 98.75
    tert-butyl acetate 153.52
    decalin 17.43
    glycerin 12.54
    diglyme 331.25
    acrylic acid 16.91
    isopropyl myristate 51.51
    n-butyric acid 77.71
    acetyl acetate 50.32
    di(2-ethylhexyl) phthalate 40.2
    ethyl propionate 84.07
    nitromethane 58.49
    1,2-diethoxyethane 154.71
    benzonitrile 37.39
    trioctyl phosphate 34.47
    1-bromopropane 61.07
    gamma-valerolactone 267.22
    n-decanol 27.29
    triethyl phosphate 72.83
    4-methyl-2-pentanol 27.95
    propionitrile 14.75
    vinylene carbonate 71.01
    1,1,2-trichlorotrifluoroethane 153.5
    DMS 57.07
    cumene 22.7
    2-octanol 41.07
    2-hexanone 89.39
    octyl acetate 60.41
    limonene 63.81
    1,2-dimethoxyethane 153.29
    ethyl orthosilicate 80.87
    tributyl phosphate 45.7
    diacetone alcohol 145.8
    N,N-dimethylaniline 44.67
    acrylonitrile 14.43
    aniline 22.88
    1,3-propanediol 18.66
    bromobenzene 45.97
    dibromomethane 106.33
    1,1,2,2-tetrachloroethane 219.77
    2-methyl-cyclohexyl acetate 120.53
    tetrabutyl urea 66.71
    diisobutyl methanol 46.97
    2-phenylethanol 36.59
    styrene 21.08
    dioctyl adipate 89.26
    dimethyl sulfate 50.18
    ethyl butyrate 131.49
    methyl lactate 27.64
    butyl lactate 117.14
    diethyl carbonate 61.96
    propanediol butyl ether 85.89
    triethyl orthoformate 125.52
    p-tert-butyltoluene 33.1
    methyl 4-tert-butylbenzoate 125.55
    morpholine 116.54
    tert-butylamine 28.27
    n-dodecanol 18.26
    dimethoxymethane 46.89
    ethylene carbonate 72.35
    cyrene 97.28
    2-ethoxyethyl acetate 165.18
    2-ethylhexyl acetate 110.48
    1,2,4-trichlorobenzene 75.77
    4-methylpyridine 51.97
    dibutyl ether 102.5
    2,6-dimethyl-4-heptanol 46.97
    DEF 91.52
    dimethyl isosorbide 212.42
    tetrachloroethylene 147.94
    eugenol 90.83
    triacetin 166.59
    span 80 93.22
    1,4-butanediol 8.44
    1,1-dichloroethane 80.55
    2-methyl-1-pentanol 35.2
    methyl formate 14.69
    2-methyl-1-butanol 32.84
    n-decane 10.42
    butyronitrile 23.97
    3,7-dimethyl-1-octanol 54.45
    1-chlorooctane 47.69
    1-chlorotetradecane 13.07
    n-nonane 10.27
    undecane 5.84
    tert-butylcyclohexane 14.27
    cyclooctane 13.48
    cyclopentanol 59.06
    tetrahydropyran 144.44
    tert-amyl methyl ether 69.49
    2,5,8-trioxanonane 181.76
    1-hexene 16.88
    2-isopropoxyethanol 61.59
    2,2,2-trifluoroethanol 18.61
    methyl butyrate 127.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction