Mintlactone, (+)-

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  • Identifiers

    CAS number
    166584-27-6

    Molecular formula
    C10H14O2

    SMILES
    C[C@H]1CCC2=C(C(=O)O[C@H]2C1)C

    Safety labels

  • Odor profile

    Fragrance
    Sweet 76.28%
    Coumarinic 65.59%
    Coconut 60.33%
    Mint 51.96%
    Lactonic 51.8%
    Tobacco 47.49%
    Hay 46.87%
    Caramellic 40.46%
    Creamy 40.4%
    Herbal 36.46%

     

    Flavor
    Minty 34.75%
    Bitter 30.47%
    Coumarin 30.42%
    Herbal 28.96%
    Tonka 25.95%
    Celery 24.72%
    Spice 24.18%
    Coconut 22.87%
    Lovage 21.85%
    Ripe apricot 21.52%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    8.71 (weak base)

    Molecular weight
    166.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    302°C

    Flash point

    • 135.11 ˚C est.

  • Synonyms

    • (+)-Mintlactone
    • 5MFC49WM8L
    • 166584-27-6
    • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, (6S,7aS)-
    • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, (6S-trans)-
    • MINTLACTONE, (+)-
    • RefChem:201780
    • Mintlactone, (+/-)-
    • UNII-5MFC49WM8L
    • (+/-)-Mintlactone
    • (6R,7aR)-3,6-Dimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one
    • SCHEMBL30689552
    • DTXSID60168130
    • Q27262560
    • (6S,7aS)-3,6-Dimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one
    • 166584-27-6

  • Applications

    Mintlactone, (+)- is a chiral lactone with a minty aroma, used as a fragrance ingredient in the fragrance and cosmetics industries. Typical applications include its use as a fragrance note in perfumery and cosmetics; it may be evaluated for household cleaning products to impart a minty scent; it can serve as an intermediate in organic synthesis to develop mint-related aroma compounds; it may be considered for flavor/aroma applications in food processing; in industrial manufacturing it can function as a specialty ingredient for fragrance formulation, subject to regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 217.87
    methanol 222.24
    isopropanol 247.2
    water 1.41
    ethyl acetate 288.15
    n-propanol 200.86
    acetone 316.53
    n-butanol 182.68
    acetonitrile 375.62
    DMF 463.23
    toluene 232.1
    isobutanol 165.87
    1,4-dioxane 616.5
    methyl acetate 332.51
    THF 476.58
    2-butanone 326.47
    n-pentanol 116.91
    sec-butanol 189.69
    n-hexane 4.1
    ethylene glycol 48.43
    NMP 308.24
    cyclohexane 18.34
    DMSO 197.7
    n-butyl acetate 220.95
    n-octanol 105.54
    chloroform 1166.12
    n-propyl acetate 163.9
    acetic acid 248.21
    dichloromethane 943.25
    cyclohexanone 418.57
    propylene glycol 71.16
    isopropyl acetate 183.53
    DMAc 305.91
    2-ethoxyethanol 172.73
    isopentanol 177.65
    n-heptane 5.65
    ethyl formate 247.85
    1,2-dichloroethane 391.4
    n-hexanol 167.56
    2-methoxyethanol 309.49
    isobutyl acetate 113.9
    tetrachloromethane 114.2
    n-pentyl acetate 143.45
    transcutol 754.93
    n-heptanol 89.09
    ethylbenzene 94.51
    MIBK 150.38
    2-propoxyethanol 280.5
    tert-butanol 258.16
    MTBE 155.6
    2-butoxyethanol 179.89
    propionic acid 198.69
    o-xylene 136.7
    formic acid 95.17
    diethyl ether 136.87
    m-xylene 150.83
    p-xylene 153.34
    chlorobenzene 326.6
    dimethyl carbonate 112.85
    n-octane 4.87
    formamide 190.62
    cyclopentanone 409.26
    2-pentanone 205.22
    anisole 212.95
    cyclopentyl methyl ether 164.78
    gamma-butyrolactone 481.27
    1-methoxy-2-propanol 249.8
    pyridine 570.05
    3-pentanone 152.13
    furfural 507.88
    n-dodecane 8.53
    diethylene glycol 234.72
    diisopropyl ether 49.82
    tert-amyl alcohol 172.06
    acetylacetone 271.93
    n-hexadecane 10.12
    acetophenone 200.46
    methyl propionate 194.64
    isopentyl acetate 212.64
    trichloroethylene 902.19
    n-nonanol 95.26
    cyclohexanol 171.85
    benzyl alcohol 189.45
    2-ethylhexanol 95.22
    isooctanol 81.36
    dipropyl ether 60.56
    1,2-dichlorobenzene 283.35
    ethyl lactate 89.42
    propylene carbonate 321.55
    n-methylformamide 250.81
    2-pentanol 117.58
    n-pentane 6.85
    1-propoxy-2-propanol 181.82
    1-methoxy-2-propyl acetate 225.66
    2-(2-methoxypropoxy) propanol 216.58
    mesitylene 89.57
    ε-caprolactone 368.02
    p-cymene 70.19
    epichlorohydrin 544.72
    1,1,1-trichloroethane 431.91
    2-aminoethanol 109.7
    morpholine-4-carbaldehyde 457.51
    sulfolane 322.56
    2,2,4-trimethylpentane 8.29
    2-methyltetrahydrofuran 333.64
    n-hexyl acetate 215.04
    isooctane 8.21
    2-(2-butoxyethoxy)ethanol 285.86
    sec-butyl acetate 119.9
    tert-butyl acetate 166.18
    decalin 12.75
    glycerin 101.89
    diglyme 457.39
    acrylic acid 175.39
    isopropyl myristate 92.76
    n-butyric acid 269.53
    acetyl acetate 207.91
    di(2-ethylhexyl) phthalate 113.73
    ethyl propionate 131.96
    nitromethane 463.24
    1,2-diethoxyethane 216.09
    benzonitrile 379.2
    trioctyl phosphate 72.98
    1-bromopropane 184.65
    gamma-valerolactone 543.47
    n-decanol 74.85
    triethyl phosphate 73.05
    4-methyl-2-pentanol 98.76
    propionitrile 280.36
    vinylene carbonate 358.91
    1,1,2-trichlorotrifluoroethane 284.75
    DMS 202.73
    cumene 69.1
    2-octanol 70.72
    2-hexanone 141.49
    octyl acetate 118.98
    limonene 81.41
    1,2-dimethoxyethane 294.32
    ethyl orthosilicate 66.84
    tributyl phosphate 91.28
    diacetone alcohol 189.8
    N,N-dimethylaniline 119.57
    acrylonitrile 401.43
    aniline 263.44
    1,3-propanediol 182.9
    bromobenzene 350.2
    dibromomethane 524.29
    1,1,2,2-tetrachloroethane 587.41
    2-methyl-cyclohexyl acetate 133.16
    tetrabutyl urea 108.41
    diisobutyl methanol 63.56
    2-phenylethanol 212.86
    styrene 119.8
    dioctyl adipate 128.73
    dimethyl sulfate 131.64
    ethyl butyrate 132.44
    methyl lactate 110.62
    butyl lactate 122.31
    diethyl carbonate 116.11
    propanediol butyl ether 169.99
    triethyl orthoformate 96.17
    p-tert-butyltoluene 64.22
    methyl 4-tert-butylbenzoate 182.25
    morpholine 542.67
    tert-butylamine 138.32
    n-dodecanol 58.34
    dimethoxymethane 255.79
    ethylene carbonate 288.4
    cyrene 164.16
    2-ethoxyethyl acetate 226.84
    2-ethylhexyl acetate 152.82
    1,2,4-trichlorobenzene 316.75
    4-methylpyridine 532.81
    dibutyl ether 87.82
    2,6-dimethyl-4-heptanol 63.56
    DEF 213.09
    dimethyl isosorbide 303.91
    tetrachloroethylene 366.64
    eugenol 196.32
    triacetin 204.56
    span 80 178.32
    1,4-butanediol 75.84
    1,1-dichloroethane 477.71
    2-methyl-1-pentanol 127.34
    methyl formate 207.5
    2-methyl-1-butanol 147.41
    n-decane 11.34
    butyronitrile 282.06
    3,7-dimethyl-1-octanol 118.0
    1-chlorooctane 59.91
    1-chlorotetradecane 29.69
    n-nonane 8.75
    undecane 9.81
    tert-butylcyclohexane 11.94
    cyclooctane 5.89
    cyclopentanol 179.41
    tetrahydropyran 343.14
    tert-amyl methyl ether 94.76
    2,5,8-trioxanonane 340.74
    1-hexene 29.76
    2-isopropoxyethanol 142.23
    2,2,2-trifluoroethanol 111.23
    methyl butyrate 175.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction