Methyltris(trimethylsiloxy)silane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    17928-28-8

    Molecular formula
    C10H30O3Si4

    SMILES
    C[Si](C)(C)O[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 34.09%
    Green 30.83%
    Mint 29.18%
    Alcoholic 24.34%
    Fresh 23.42%
    Cooling 23.2%
    Camphoreous 21.25%
    Ethereal 20.92%
    Sulfurous 20.54%
    Woody 20.05%

     

    Flavor
    Green 31.32%
    Pungent 24.99%
    Mild 22.4%
    Sweet 22.29%
    Earthy 21.51%
    Bitter 20.25%
    Rose acetate 20.14%
    Catty 19.95%
    Black currant 19.83%
    Blackberry 19.8%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.56 (neutral)

    Molecular weight
    310.68 g/mol

    Melting point expt.

    • -105 °F (NTP, 1992)

    Boiling point

    • 381 °F at 760 mmHg (NTP, 1992)

    Flash point

    • 71.27 ˚C est.
    • 187 °F (NTP, 1992)

    Solubility expt.

    • less than 1 mg/mL at 68 °F (NTP, 1992)

  • Synonyms

    • METHYLTRIS(TRIMETHYLSILOXY)SILANE
    • Methyl trimethicone
    • methyl tris(trimethylsiloxy)silane
    • Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]-
    • 1,1,1,3,5,5,5-Heptamethyl-3-((trimethylsilyl)oxy)trisiloxane
    • 1,1,1,3,5,5,5-Heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane
    • UNII-S73ZQI0GXM
    • S73ZQI0GXM
    • EINECS 241-867-7
    • Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-((trimethylsilyl)oxy)-
    • tris(trimethylsiloxy)methylsilane
    • DTXSID9025669
    • TMF-1.5
    • EC 241-867-7
    • Methyl tris-(trimethylsilyloxy)silane
    • RefChem:158355
    • DTXCID105669
    • METHYL TRIMETHICONE [INCI]
    • RGMZNZABJYWAEC-UHFFFAOYSA-N
    • 17928-28-8
    • trimethyl-[methyl-bis(trimethylsilyloxy)silyl]oxysilane
    • MFCD00040007
    • s12125
    • 1,1,1,3,5,5,5-heptamethyl-3-trimethylsilanyloxy-trisiloxane
    • Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-3-(trimethylsiloxy)-
    • SCHEMBL41363
    • SCHEMBL1181319
    • CHEBI:144342
    • 1,1,1,3,5,5,5-HEPTAMETHYL-3-(TRIMETHYLSILOXY)TRISILOXANE
    • MSK180268
    • AKOS024462729
    • FS-3855
    • MSK180268-100M
    • 2,2,4,6,6-pentamethyl-4-[(trimethylsilyl)oxy]-3,5-dioxa-2,4,6-trisilaheptane
    • SY234853
    • DB-044358
    • H1612
    • NS00051751
    • D91052
    • Q27288754
    • trimethyl-[methyl-bis(trimethylsilyloxy)silyl]oxy-silane
    • Methyltris(trimethylsiloxy)silane Solution in Methanol, 100ug/mL
    • 17928-28-8

  • Applications

    Methyltris(trimethylsiloxy)silane (CAS number: 17928-28-8) is used primarily as a reactive silane building block in coatings, adhesives, and polymer formulations. It functions as a silane coupling agent and crosslinker, enabling network formation upon hydrolysis and condensation and improving bonding to inorganic substrates. In sol-gel processes, it serves as a precursor to silicone resins and Si-O-Si networks. It is also employed for surface modification of glass, metals, and ceramics to impart tailored hydrophobicity or adhesion characteristics. Additionally, it can be an intermediate in the synthesis of specialty silicone polymers and electronic/optical materials for electronics applications; use is formulation- and regulation-dependent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 358.36
    methanol 372.22
    isopropanol 360.11
    water 14.96
    ethyl acetate 330.2
    n-propanol 373.39
    acetone 494.52
    n-butanol 355.62
    acetonitrile 205.23
    DMF 842.02
    toluene 331.2
    isobutanol 286.25
    1,4-dioxane 572.24
    methyl acetate 314.43
    THF 1525.11
    2-butanone 413.96
    n-pentanol 291.74
    sec-butanol 364.07
    n-hexane 194.42
    ethylene glycol 125.42
    NMP 1103.63
    cyclohexane 356.57
    DMSO 707.97
    n-butyl acetate 356.17
    n-octanol 370.77
    chloroform 864.2
    n-propyl acetate 296.97
    acetic acid 344.83
    dichloromethane 654.73
    cyclohexanone 830.85
    propylene glycol 269.21
    isopropyl acetate 290.69
    DMAc 653.04
    2-ethoxyethanol 315.39
    isopentanol 260.84
    n-heptane 192.63
    ethyl formate 270.84
    1,2-dichloroethane 400.52
    n-hexanol 406.67
    2-methoxyethanol 499.46
    isobutyl acetate 233.88
    tetrachloromethane 192.64
    n-pentyl acetate 367.48
    transcutol 498.18
    n-heptanol 306.49
    ethylbenzene 201.7
    MIBK 288.5
    2-propoxyethanol 554.08
    tert-butanol 380.65
    MTBE 261.39
    2-butoxyethanol 369.04
    propionic acid 341.82
    o-xylene 211.3
    formic acid 140.98
    diethyl ether 327.7
    m-xylene 250.64
    p-xylene 250.85
    chlorobenzene 353.28
    dimethyl carbonate 241.55
    n-octane 117.6
    formamide 207.99
    cyclopentanone 1122.23
    2-pentanone 398.0
    anisole 322.8
    cyclopentyl methyl ether 688.5
    gamma-butyrolactone 1068.45
    1-methoxy-2-propanol 579.71
    pyridine 570.24
    3-pentanone 309.5
    furfural 808.32
    n-dodecane 88.15
    diethylene glycol 313.25
    diisopropyl ether 173.31
    tert-amyl alcohol 318.96
    acetylacetone 472.11
    n-hexadecane 96.1
    acetophenone 334.84
    methyl propionate 361.91
    isopentyl acetate 290.46
    trichloroethylene 659.9
    n-nonanol 335.87
    cyclohexanol 513.04
    benzyl alcohol 271.37
    2-ethylhexanol 257.97
    isooctanol 236.31
    dipropyl ether 350.88
    1,2-dichlorobenzene 312.58
    ethyl lactate 234.86
    propylene carbonate 656.77
    n-methylformamide 399.23
    2-pentanol 310.71
    n-pentane 192.13
    1-propoxy-2-propanol 489.39
    1-methoxy-2-propyl acetate 406.22
    2-(2-methoxypropoxy) propanol 299.03
    mesitylene 185.29
    ε-caprolactone 692.02
    p-cymene 160.26
    epichlorohydrin 721.42
    1,1,1-trichloroethane 430.95
    2-aminoethanol 241.57
    morpholine-4-carbaldehyde 801.87
    sulfolane 1318.75
    2,2,4-trimethylpentane 76.64
    2-methyltetrahydrofuran 772.92
    n-hexyl acetate 498.94
    isooctane 73.24
    2-(2-butoxyethoxy)ethanol 429.85
    sec-butyl acetate 229.58
    tert-butyl acetate 320.03
    decalin 134.59
    glycerin 320.01
    diglyme 559.52
    acrylic acid 298.37
    isopropyl myristate 253.28
    n-butyric acid 433.13
    acetyl acetate 275.73
    di(2-ethylhexyl) phthalate 221.01
    ethyl propionate 287.26
    nitromethane 448.17
    1,2-diethoxyethane 292.3
    benzonitrile 302.28
    trioctyl phosphate 208.05
    1-bromopropane 365.04
    gamma-valerolactone 1092.2
    n-decanol 258.43
    triethyl phosphate 181.51
    4-methyl-2-pentanol 202.41
    propionitrile 236.34
    vinylene carbonate 555.15
    1,1,2-trichlorotrifluoroethane 572.82
    DMS 318.07
    cumene 150.23
    2-octanol 290.17
    2-hexanone 328.35
    octyl acetate 324.18
    limonene 248.87
    1,2-dimethoxyethane 475.55
    ethyl orthosilicate 179.12
    tributyl phosphate 206.74
    diacetone alcohol 379.03
    N,N-dimethylaniline 269.94
    acrylonitrile 266.48
    aniline 348.46
    1,3-propanediol 290.27
    bromobenzene 362.69
    dibromomethane 525.34
    1,1,2,2-tetrachloroethane 649.99
    2-methyl-cyclohexyl acetate 328.52
    tetrabutyl urea 303.28
    diisobutyl methanol 178.86
    2-phenylethanol 317.79
    styrene 229.17
    dioctyl adipate 305.65
    dimethyl sulfate 377.96
    ethyl butyrate 303.93
    methyl lactate 322.1
    butyl lactate 351.93
    diethyl carbonate 203.89
    propanediol butyl ether 405.37
    triethyl orthoformate 260.6
    p-tert-butyltoluene 179.48
    methyl 4-tert-butylbenzoate 368.75
    morpholine 732.44
    tert-butylamine 294.23
    n-dodecanol 209.79
    dimethoxymethane 578.77
    ethylene carbonate 467.71
    cyrene 416.34
    2-ethoxyethyl acetate 338.83
    2-ethylhexyl acetate 264.96
    1,2,4-trichlorobenzene 387.77
    4-methylpyridine 530.72
    dibutyl ether 316.74
    2,6-dimethyl-4-heptanol 178.86
    DEF 428.47
    dimethyl isosorbide 576.33
    tetrachloroethylene 381.58
    eugenol 359.29
    triacetin 394.1
    span 80 474.48
    1,4-butanediol 152.65
    1,1-dichloroethane 414.62
    2-methyl-1-pentanol 215.11
    methyl formate 315.88
    2-methyl-1-butanol 261.16
    n-decane 143.81
    butyronitrile 267.79
    3,7-dimethyl-1-octanol 264.07
    1-chlorooctane 286.82
    1-chlorotetradecane 144.17
    n-nonane 149.14
    undecane 107.42
    tert-butylcyclohexane 121.76
    cyclooctane 176.33
    cyclopentanol 665.76
    tetrahydropyran 804.24
    tert-amyl methyl ether 249.03
    2,5,8-trioxanonane 443.14
    1-hexene 303.52
    2-isopropoxyethanol 247.83
    2,2,2-trifluoroethanol 171.75
    methyl butyrate 345.44

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction