Methylsilanol acetylmethionate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    105883-43-0

    Molecular formula
    C8H17NO5SSi

    SMILES
    CC(=O)N[C@@H](CCSC)C(=O)O[Si](C)(O)O

    Safety labels

  • Odor profile

    Fragrance
    Meaty 46.81%
    Savory 43.36%
    Odorless 38.93%
    Sulfurous 38.39%
    Roasted 30.99%
    Sweet 30.8%
    Cooked 27.11%
    Tropical 24.42%
    Onion 23.4%
    Milky 21.76%

     

    Flavor
    Odorless 54.35%
    Mild 33.24%
    Bland 27.25%
    Sulfury 23.38%
    Sweet-like 22.52%
    Very mild 22.43%
    Bitter 21.58%
    Yeast 21.42%
    Stinky 20.46%
    Acrid 20.2%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    9.24 (weak base)

    Molecular weight
    267.38 g/mol

    Flash point

    • 176.76 ˚C est.

  • Synonyms

    • Methylsilanol acetylmethionate
    • FKT0KP5RFC
    • UNII-FKT0KP5RFC
    • 105883-43-0
    • L-Methionine, N-acetyl-, dihydroxymethylsilyl ester
    • DTXSID80147381
    • DIHYDROXYMETHYLSILYL N-ACETYLMETHIONATE
    • RefChem:158310
    • DTXCID6069872
    • METHYLSILANOL ACETYLMETHIONATE [INCI]
    • orb1701934
    • AKOS040747154
    • Dihydroxy(methyl)silyl N-acetyl-L-methioninate
    • Q27278039
    • [dihydroxy(methyl)silyl] (2S)-2-acetamido-4-methylsulfanylbutanoate
    • 105883-43-0

  • Applications

    Methylsilanol acetylmethionate (CAS 105883-43-0) is used as a reactive silanol-functional additive in silicone and polymer formulations, serving as a crosslinking/functionalization precursor that helps form siloxane networks. It also acts as a surface-modifying or coupling agent for inorganic fillers, pigments, and substrates in coatings, adhesives, and plastics, improving wetting, adhesion, and dispersion. In cosmetics and personal care, it can function as a conditioning agent and texture modifier, contributing slip and film-forming properties. In coatings and inks, it supports improved adhesion and durability when incorporated as a reactive additive. Additionally, it may be evaluated as a silanol-functional precursor for silicone resins used in electronics encapsulation and sealants, where controlled network formation is desired. Applications and performance are subject to formulation and regulatory considerations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 86.98
    methanol 184.3
    isopropanol 34.08
    water 64.36
    ethyl acetate 5.77
    n-propanol 49.99
    acetone 38.05
    n-butanol 32.96
    acetonitrile 8.28
    DMF 377.04
    toluene 1.81
    isobutanol 22.88
    1,4-dioxane 22.2
    methyl acetate 9.29
    THF 110.13
    2-butanone 16.44
    n-pentanol 19.42
    sec-butanol 23.63
    n-hexane 0.68
    ethylene glycol 109.96
    NMP 250.51
    cyclohexane 0.92
    DMSO 421.1
    n-butyl acetate 9.05
    n-octanol 5.68
    chloroform 4.7
    n-propyl acetate 7.24
    acetic acid 100.68
    dichloromethane 5.04
    cyclohexanone 30.78
    propylene glycol 101.78
    isopropyl acetate 4.5
    DMAc 223.41
    2-ethoxyethanol 91.24
    isopentanol 18.09
    n-heptane 0.53
    ethyl formate 28.57
    1,2-dichloroethane 5.64
    n-hexanol 14.17
    2-methoxyethanol 255.5
    isobutyl acetate 3.87
    tetrachloromethane 1.48
    n-pentyl acetate 5.67
    transcutol 56.97
    n-heptanol 7.9
    ethylbenzene 1.42
    MIBK 8.46
    2-propoxyethanol 68.98
    tert-butanol 30.74
    MTBE 5.08
    2-butoxyethanol 34.62
    propionic acid 35.89
    o-xylene 1.84
    formic acid 251.63
    diethyl ether 4.83
    m-xylene 1.61
    p-xylene 1.73
    chlorobenzene 1.89
    dimethyl carbonate 11.89
    n-octane 0.22
    formamide 235.8
    cyclopentanone 66.59
    2-pentanone 13.1
    anisole 5.88
    cyclopentyl methyl ether 15.5
    gamma-butyrolactone 79.15
    1-methoxy-2-propanol 99.31
    pyridine 17.08
    3-pentanone 7.44
    furfural 96.35
    n-dodecane 0.18
    diethylene glycol 113.09
    diisopropyl ether 1.17
    tert-amyl alcohol 21.32
    acetylacetone 18.96
    n-hexadecane 0.2
    acetophenone 11.3
    methyl propionate 10.65
    isopentyl acetate 8.3
    trichloroethylene 8.29
    n-nonanol 5.2
    cyclohexanol 16.7
    benzyl alcohol 14.76
    2-ethylhexanol 5.77
    isooctanol 5.1
    dipropyl ether 4.27
    1,2-dichlorobenzene 2.35
    ethyl lactate 16.07
    propylene carbonate 33.97
    n-methylformamide 180.23
    2-pentanol 11.34
    n-pentane 0.65
    1-propoxy-2-propanol 31.98
    1-methoxy-2-propyl acetate 14.8
    2-(2-methoxypropoxy) propanol 29.77
    mesitylene 1.17
    ε-caprolactone 30.84
    p-cymene 1.61
    epichlorohydrin 45.64
    1,1,1-trichloroethane 2.52
    2-aminoethanol 144.29
    morpholine-4-carbaldehyde 149.17
    sulfolane 160.98
    2,2,4-trimethylpentane 0.25
    2-methyltetrahydrofuran 25.9
    n-hexyl acetate 7.33
    isooctane 0.17
    2-(2-butoxyethoxy)ethanol 38.68
    sec-butyl acetate 3.54
    tert-butyl acetate 7.1
    decalin 0.42
    glycerin 215.74
    diglyme 66.62
    acrylic acid 46.86
    isopropyl myristate 2.77
    n-butyric acid 33.83
    acetyl acetate 4.97
    di(2-ethylhexyl) phthalate 7.94
    ethyl propionate 6.22
    nitromethane 97.1
    1,2-diethoxyethane 6.21
    benzonitrile 7.59
    trioctyl phosphate 5.73
    1-bromopropane 2.6
    gamma-valerolactone 118.41
    n-decanol 3.56
    triethyl phosphate 7.18
    4-methyl-2-pentanol 5.44
    propionitrile 7.37
    vinylene carbonate 28.97
    1,1,2-trichlorotrifluoroethane 85.25
    DMS 6.52
    cumene 1.24
    2-octanol 3.86
    2-hexanone 9.9
    octyl acetate 4.39
    limonene 2.15
    1,2-dimethoxyethane 90.0
    ethyl orthosilicate 6.14
    tributyl phosphate 6.28
    diacetone alcohol 28.42
    N,N-dimethylaniline 7.74
    acrylonitrile 13.91
    aniline 8.01
    1,3-propanediol 128.33
    bromobenzene 1.19
    dibromomethane 3.33
    1,1,2,2-tetrachloroethane 8.97
    2-methyl-cyclohexyl acetate 8.74
    tetrabutyl urea 12.53
    diisobutyl methanol 2.87
    2-phenylethanol 11.93
    styrene 1.54
    dioctyl adipate 6.86
    dimethyl sulfate 34.46
    ethyl butyrate 7.48
    methyl lactate 33.42
    butyl lactate 13.77
    diethyl carbonate 6.04
    propanediol butyl ether 36.64
    triethyl orthoformate 7.22
    p-tert-butyltoluene 1.56
    methyl 4-tert-butylbenzoate 15.2
    morpholine 53.8
    tert-butylamine 9.73
    n-dodecanol 2.46
    dimethoxymethane 67.54
    ethylene carbonate 20.9
    cyrene 47.81
    2-ethoxyethyl acetate 8.56
    2-ethylhexyl acetate 6.07
    1,2,4-trichlorobenzene 3.57
    4-methylpyridine 13.43
    dibutyl ether 2.31
    2,6-dimethyl-4-heptanol 2.87
    DEF 30.52
    dimethyl isosorbide 52.26
    tetrachloroethylene 7.2
    eugenol 22.11
    triacetin 9.49
    span 80 21.8
    1,4-butanediol 45.3
    1,1-dichloroethane 2.49
    2-methyl-1-pentanol 11.76
    methyl formate 102.87
    2-methyl-1-butanol 18.98
    n-decane 0.3
    butyronitrile 8.62
    3,7-dimethyl-1-octanol 4.41
    1-chlorooctane 1.17
    1-chlorotetradecane 0.53
    n-nonane 0.27
    undecane 0.22
    tert-butylcyclohexane 0.32
    cyclooctane 0.33
    cyclopentanol 36.29
    tetrahydropyran 13.93
    tert-amyl methyl ether 5.3
    2,5,8-trioxanonane 48.2
    1-hexene 2.19
    2-isopropoxyethanol 31.21
    2,2,2-trifluoroethanol 44.28
    methyl butyrate 12.84

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction