Methylparaben Sodium

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  • Identifiers

    CAS number
    5026-62-0

    Molecular formula
    C8H7NaO3

    SMILES
    COC(=O)C1=CC=C(C=C1)[O-].[Na+]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 56.74%
    Sweet 55.41%
    Floral 46.81%
    Fruity 39.7%
    Vanilla 38.74%
    Grape 37.68%
    Powdery 34.41%
    Aromatic 34.31%
    Cherry 31.91%
    Hawthorn 31.9%

     

    Flavor
    Sweet 51.86%
    Bitter 42.82%
    Balsam 42.55%
    Wintergreen 40.29%
    Powdery 38.68%
    Fruity 36.91%
    Floral 33.7%
    Herbal 32.88%
    Phenolic 32.73%
    Grape 31.9%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    5.42 (weak acid)

    Molecular weight
    174.13 g/mol

    Melting point expt.

    • The white precipitate formed by acidifying with hydrochloric acid a 10 % (w/v) aqueous solution of the sodium derivative of methylp-hydroxybenzoate (using litmus paper as indicator) shall, when washed with water and dried at 80 °C for two hours, have a melting range of 125 °C to 128 °C

    Flash point

    • 96.95 ˚C est.

  • Synonyms

    • Methylparaben sodium
    • sodium methyl paraben
    • Paratexin ms
    • Paridol mna
    • Nipagin m sodium
    • Solbrol m sodium salt
    • CR6K9C2NHK
    • Methylparaben, sodium salt
    • Ns 3500s
    • DTXSID1042156
    • RefChem:158282
    • DTXCID9022156
    • 225-714-1
    • 5026-62-0
    • Sodium 4-(methoxycarbonyl)phenolate
    • Sodium methylparaben
    • Methyl 4-hydroxybenzoate, sodium salt
    • Methyl 4-hydroxybenzoate sodium salt
    • Sodium 4-carbomethoxyphenolate
    • MFCD00016470
    • Sodium methyl p-hydroxybenzoate
    • Sodium Methyl Parahydroxybenzoate
    • sodium;4-methoxycarbonylphenolate
    • Sodium methyl 4-hydroxybenzoate
    • Methylparaben sodium salt
    • Sodium methylparaben, 99%
    • 4-Hydroxybenzoic acid-methyl ester sodium
    • Preserval MS
    • Solparol
    • Bonomold OMNa
    • Methylparaben sodium [USAN]
    • Sodium p-methoxycarbonylphenoxide
    • Sodium Methyl Parahydroxybenzoate; SKF-4382-Z
    • EINECS 225-714-1
    • UNII-CR6K9C2NHK
    • Methyl p-hydroxybenzoate, sodium salt
    • Sodium nipagin
    • Methylparaben sodium [USAN:NF]
    • Nipagin Monosodium
    • Methylis parahydroxybenzoas natricum
    • methyl paraben sodium
    • Sodium, (p-carboxyphenoxy)-, methyl ester
    • Methylparaben sodium (NF)
    • EC 225-714-1
    • sodium 4carbomethoxyphenolate
    • sodium methyl hydroxybenzoate
    • SCHEMBL48756
    • Methyl 4-hydroxybenzoate sodium
    • orb2646176
    • CHEMBL2106903
    • Sodium p-methoxycarbonylphenolate
    • METHYLPARABEN SODIUM [II]
    • sodium methyl para-hydroxybenzoate
    • Methyl p-hydroxybenzoate sodium salt
    • AKOS015961950
    • CS-W017522
    • FM01505
    • HY-W016806
    • AC-15527
    • AS-14805
    • SY110465
    • NS00078333
    • SODIUM METHYL HYDROXYBENZOATE [MART.]
    • ST50405340
    • 4-hydroxybenzoic acid methyl ester sodium salt
    • A11551
    • D02458
    • F319782
    • SODIUM METHYL P-HYDROXYBENZOATE ( E 219)
    • Q3963920
    • SODIUM METHYL PARAHYDROXYBENZOATE [EP MONOGRAPH]
    • BENZOIC ACID, p-HYDROXY-, METHYL ESTER, SODIUM DERIV.
    • Methyl 4-hydroxybenzoate sodium salt, tested according to Ph.Eur.
    • 5026-62-0

  • Applications

    Methylparaben Sodium (CAS 5026-62-0) is a water-soluble preservative widely used in cosmetics and personal care products (lotions, creams, shampoos, gels) to inhibit microbial growth. It is also used as a preservative in pharmaceutical topical formulations (creams, gels) to extend shelf life. In household cleaning products and laundry detergents, it provides antimicrobial protection in aqueous systems. In industrial, water-based formulations such as paints, coatings, adhesives, and inks, it can function as a preservative to prevent microbial contamination and improve formulation stability. Use and limits are subject to local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 280.62
    methanol 289.23
    isopropanol 206.15
    water 7.62
    ethyl acetate 296.03
    n-propanol 178.32
    acetone 1019.95
    n-butanol 118.26
    acetonitrile 478.92
    DMF 2084.67
    toluene 92.29
    isobutanol 101.17
    1,4-dioxane 556.75
    methyl acetate 475.81
    THF 780.39
    2-butanone 539.6
    n-pentanol 112.39
    sec-butanol 174.05
    n-hexane 13.53
    ethylene glycol 146.4
    NMP 1535.49
    cyclohexane 10.78
    DMSO 2658.78
    n-butyl acetate 200.05
    n-octanol 53.76
    chloroform 338.38
    n-propyl acetate 256.24
    acetic acid 447.25
    dichloromethane 580.79
    cyclohexanone 408.76
    propylene glycol 112.56
    isopropyl acetate 172.43
    DMAc 1104.23
    2-ethoxyethanol 484.4
    isopentanol 97.29
    n-heptane 7.3
    ethyl formate 255.5
    1,2-dichloroethane 488.64
    n-hexanol 84.58
    2-methoxyethanol 597.02
    isobutyl acetate 86.42
    tetrachloromethane 66.47
    n-pentyl acetate 113.34
    transcutol 1492.1
    n-heptanol 44.16
    ethylbenzene 81.52
    MIBK 171.77
    2-propoxyethanol 273.48
    tert-butanol 240.17
    MTBE 239.1
    2-butoxyethanol 160.69
    propionic acid 284.46
    o-xylene 96.08
    formic acid 375.47
    diethyl ether 264.88
    m-xylene 75.53
    p-xylene 86.59
    chlorobenzene 175.21
    dimethyl carbonate 272.72
    n-octane 2.83
    formamide 1142.3
    cyclopentanone 798.8
    2-pentanone 339.77
    anisole 410.91
    cyclopentyl methyl ether 275.39
    gamma-butyrolactone 1016.52
    1-methoxy-2-propanol 421.44
    pyridine 472.8
    3-pentanone 271.23
    furfural 975.34
    n-dodecane 2.39
    diethylene glycol 303.1
    diisopropyl ether 66.5
    tert-amyl alcohol 209.59
    acetylacetone 553.19
    n-hexadecane 2.92
    acetophenone 389.29
    methyl propionate 343.07
    isopentyl acetate 147.82
    trichloroethylene 890.77
    n-nonanol 48.28
    cyclohexanol 104.99
    benzyl alcohol 238.91
    2-ethylhexanol 52.77
    isooctanol 37.29
    dipropyl ether 88.6
    1,2-dichlorobenzene 212.42
    ethyl lactate 160.68
    propylene carbonate 389.89
    n-methylformamide 944.62
    2-pentanol 105.06
    n-pentane 11.13
    1-propoxy-2-propanol 187.95
    1-methoxy-2-propyl acetate 257.34
    2-(2-methoxypropoxy) propanol 259.4
    mesitylene 48.2
    ε-caprolactone 404.13
    p-cymene 42.44
    epichlorohydrin 1068.65
    1,1,1-trichloroethane 262.85
    2-aminoethanol 187.14
    morpholine-4-carbaldehyde 1124.43
    sulfolane 1403.19
    2,2,4-trimethylpentane 9.79
    2-methyltetrahydrofuran 497.28
    n-hexyl acetate 168.47
    isooctane 5.92
    2-(2-butoxyethoxy)ethanol 322.24
    sec-butyl acetate 138.03
    tert-butyl acetate 232.44
    decalin 11.36
    glycerin 207.83
    diglyme 767.73
    acrylic acid 368.32
    isopropyl myristate 60.88
    n-butyric acid 188.78
    acetyl acetate 201.57
    di(2-ethylhexyl) phthalate 63.33
    ethyl propionate 213.45
    nitromethane 1709.91
    1,2-diethoxyethane 314.29
    benzonitrile 254.26
    trioctyl phosphate 44.32
    1-bromopropane 158.59
    gamma-valerolactone 910.4
    n-decanol 34.44
    triethyl phosphate 89.89
    4-methyl-2-pentanol 53.89
    propionitrile 217.08
    vinylene carbonate 353.77
    1,1,2-trichlorotrifluoroethane 594.31
    DMS 265.84
    cumene 56.06
    2-octanol 33.87
    2-hexanone 269.19
    octyl acetate 84.72
    limonene 56.88
    1,2-dimethoxyethane 686.14
    ethyl orthosilicate 72.91
    tributyl phosphate 66.53
    diacetone alcohol 289.68
    N,N-dimethylaniline 262.17
    acrylonitrile 421.04
    aniline 202.59
    1,3-propanediol 213.68
    bromobenzene 151.72
    dibromomethane 291.89
    1,1,2,2-tetrachloroethane 530.45
    2-methyl-cyclohexyl acetate 123.45
    tetrabutyl urea 97.88
    diisobutyl methanol 36.41
    2-phenylethanol 155.78
    styrene 125.26
    dioctyl adipate 124.26
    dimethyl sulfate 622.0
    ethyl butyrate 148.46
    methyl lactate 228.76
    butyl lactate 116.12
    diethyl carbonate 113.54
    propanediol butyl ether 195.16
    triethyl orthoformate 98.33
    p-tert-butyltoluene 39.69
    methyl 4-tert-butylbenzoate 199.61
    morpholine 667.3
    tert-butylamine 110.33
    n-dodecanol 24.82
    dimethoxymethane 685.02
    ethylene carbonate 232.91
    cyrene 273.43
    2-ethoxyethyl acetate 250.07
    2-ethylhexyl acetate 117.87
    1,2,4-trichlorobenzene 268.47
    4-methylpyridine 430.97
    dibutyl ether 77.68
    2,6-dimethyl-4-heptanol 36.41
    DEF 525.55
    dimethyl isosorbide 419.72
    tetrachloroethylene 392.19
    eugenol 211.72
    triacetin 266.61
    span 80 154.61
    1,4-butanediol 124.36
    1,1-dichloroethane 300.09
    2-methyl-1-pentanol 98.6
    methyl formate 693.51
    2-methyl-1-butanol 102.66
    n-decane 4.34
    butyronitrile 165.18
    3,7-dimethyl-1-octanol 61.29
    1-chlorooctane 30.65
    1-chlorotetradecane 11.06
    n-nonane 4.16
    undecane 3.18
    tert-butylcyclohexane 11.02
    cyclooctane 4.83
    cyclopentanol 159.28
    tetrahydropyran 302.13
    tert-amyl methyl ether 192.53
    2,5,8-trioxanonane 481.16
    1-hexene 56.99
    2-isopropoxyethanol 278.46
    2,2,2-trifluoroethanol 294.83
    methyl butyrate 286.2

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction