Methylamine hydrochloride

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  • Identifiers

    CAS number
    593-51-1

    Molecular formula
    CH6ClN

    SMILES
    CN.Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 78.57%
    Cheesy 76.12%
    Ripe 61.72%
    Odorless 32.43%
    Fermented 31.48%
    Oily 29.35%
    Pungent 24.18%
    Alcoholic 24.07%
    Sweaty 22.96%
    Meaty 20.63%

     

    Flavor
    Fishy 35.77%
    Egg 34.93%
    Gasoline 29.52%
    Rotten 28.55%
    Sulfur 28.39%
    Garlic 26.46%
    Decomposing cabbage 26.3%
    Ammoniacal 25.99%
    Ammonia 24.24%
    Pungent 19.64%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.63 (weak base)

    Molecular weight
    67.52 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    -7°C

    Flash point

    • -20.79 ˚C est.

  • Synonyms

    • Methylamine hydrochloride
    • 593-51-1
    • methanamine hydrochloride
    • Monomethylamine hydrochloride
    • METHANAMINE, HYDROCHLORIDE
    • Aminomethane Hydrochloride
    • methanaminium chloride
    • Mathylamine, hydrochloride
    • Methylamine, hydrochloride
    • NSC-89685
    • M439EX322K
    • METHYLAMINE HYDROCHLORIDE [MI]
    • Methylamine HCl
    • MFCD00064559
    • Methylaminehydrochloride
    • Methyl Amine hydrochloride
    • methanamine HCl
    • methanamine-HCl
    • methyl amine HCl
    • methyl amine-HCl
    • MeNH2 hydrochloride
    • MeNH2HCl
    • methanamine HCl salt
    • methylamine HCl salt
    • MFCD00012849
    • methylaminhydrochloride
    • CH6ClN
    • H2NMe.HCl
    • MeNH2-HCl
    • MeNH2.HCl
    • methylamin-hydrochloride
    • methylamine-hydrochoride
    • metylamine hydrochloride
    • CH3NH2HCl
    • NMethylammonium chloride
    • methyl ammonium chloride
    • methylamine-hydrochloride
    • methylamine.hydrochloride
    • Methanamine;hydrochloride
    • CH3NH2-HCl
    • CH3NH2.HCl
    • methaneamine hydrochloride
    • methylarnine hydrochloride
    • NH2CH3.HCl
    • N-methylamine hydrochloride
    • methylamine hydrochloric acid
    • Methylamine monohydrochloride
    • methylamine Hydrogen Chloride
    • methylamine hydrochloride salt
    • methyl amine Hydrogen Chloride
    • Mathylamine, hydrochloride (8CI)
    • Methylamine, hydrochloride (8CI)
    • DAA85222
    • KCA65693
    • NSC89685
    • s6232
    • AKOS015918174
    • FM76352
    • BP-11399
    • SY236298
    • DB-050375
    • M0138
    • Methylamine hydrochloride, purum, >=98.0% (AT)
    • Q27126640
    • F2191-0278
    • Methylamine hydrochloride, Vetec(TM) reagent grade, 98%
    • 209-795-0

  • Applications

    Methylamine hydrochloride (MAH) is mainly used as a source of methylamine for amination reactions and to prepare amine-containing intermediates in pharmaceutical and agrochemical synthesis. It serves as a key precursor in the manufacture of pharmaceutical products, crop protection agents, and dye/pigment intermediates by providing methylamine for amine-containing structures. It is employed in industrial-scale reductive amination and other amination pathways to form methylated amines. In certain manufacturing routes, MAH can be considered an intermediate in fragrance or flavor synthesis, depending on formulation and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 119.7
    methanol 329.8
    isopropanol 34.79
    water 66.27
    ethyl acetate 8.25
    n-propanol 66.32
    acetone 12.29
    n-butanol 43.8
    acetonitrile 17.6
    DMF 80.23
    toluene 1.09
    isobutanol 27.06
    1,4-dioxane 16.87
    methyl acetate 13.56
    THF 29.13
    2-butanone 8.62
    n-pentanol 16.85
    sec-butanol 22.94
    n-hexane 0.54
    ethylene glycol 170.06
    NMP 91.07
    cyclohexane 1.25
    DMSO 130.03
    n-butyl acetate 12.36
    n-octanol 5.02
    chloroform 31.8
    n-propyl acetate 5.49
    acetic acid 349.31
    dichloromethane 29.39
    cyclohexanone 19.35
    propylene glycol 95.78
    isopropyl acetate 2.78
    DMAc 31.77
    2-ethoxyethanol 35.51
    isopentanol 14.72
    n-heptane 1.5
    ethyl formate 30.14
    1,2-dichloroethane 13.69
    n-hexanol 20.31
    2-methoxyethanol 120.7
    isobutyl acetate 2.47
    tetrachloromethane 9.72
    n-pentyl acetate 5.59
    transcutol 33.28
    n-heptanol 9.17
    ethylbenzene 0.48
    MIBK 1.58
    2-propoxyethanol 42.71
    tert-butanol 17.93
    MTBE 2.82
    2-butoxyethanol 23.84
    propionic acid 117.04
    o-xylene 0.85
    formic acid 500.54
    diethyl ether 3.94
    m-xylene 0.66
    p-xylene 0.79
    chlorobenzene 6.04
    dimethyl carbonate 5.53
    n-octane 0.43
    formamide 266.16
    cyclopentanone 32.23
    2-pentanone 4.98
    anisole 2.09
    cyclopentyl methyl ether 7.2
    gamma-butyrolactone 71.37
    1-methoxy-2-propanol 40.49
    pyridine 28.3
    3-pentanone 3.76
    furfural 101.11
    n-dodecane 0.25
    diethylene glycol 68.7
    diisopropyl ether 0.6
    tert-amyl alcohol 13.69
    acetylacetone 5.49
    n-hexadecane 0.25
    acetophenone 3.76
    methyl propionate 10.13
    isopentyl acetate 6.46
    trichloroethylene 31.3
    n-nonanol 3.98
    cyclohexanol 21.11
    benzyl alcohol 9.12
    2-ethylhexanol 7.17
    isooctanol 5.06
    dipropyl ether 4.65
    1,2-dichlorobenzene 6.43
    ethyl lactate 10.22
    propylene carbonate 35.08
    n-methylformamide 130.6
    2-pentanol 10.54
    n-pentane 0.92
    1-propoxy-2-propanol 24.0
    1-methoxy-2-propyl acetate 8.64
    2-(2-methoxypropoxy) propanol 9.95
    mesitylene 0.44
    ε-caprolactone 25.05
    p-cymene 1.46
    epichlorohydrin 35.35
    1,1,1-trichloroethane 6.99
    2-aminoethanol 169.34
    morpholine-4-carbaldehyde 57.99
    sulfolane 108.96
    2,2,4-trimethylpentane 0.4
    2-methyltetrahydrofuran 15.4
    n-hexyl acetate 5.1
    isooctane 0.2
    2-(2-butoxyethoxy)ethanol 16.14
    sec-butyl acetate 1.91
    tert-butyl acetate 2.06
    decalin 0.33
    glycerin 160.64
    diglyme 24.46
    acrylic acid 163.18
    isopropyl myristate 1.56
    n-butyric acid 91.87
    acetyl acetate 6.62
    di(2-ethylhexyl) phthalate 5.22
    ethyl propionate 3.76
    nitromethane 137.57
    1,2-diethoxyethane 5.27
    benzonitrile 11.03
    trioctyl phosphate 3.96
    1-bromopropane 5.8
    gamma-valerolactone 52.98
    n-decanol 2.79
    triethyl phosphate 4.79
    4-methyl-2-pentanol 2.77
    propionitrile 14.8
    vinylene carbonate 41.84
    1,1,2-trichlorotrifluoroethane 99.71
    DMS 5.96
    cumene 0.51
    2-octanol 3.56
    2-hexanone 2.96
    octyl acetate 2.93
    limonene 2.37
    1,2-dimethoxyethane 17.61
    ethyl orthosilicate 3.97
    tributyl phosphate 4.68
    diacetone alcohol 7.4
    N,N-dimethylaniline 2.01
    acrylonitrile 33.04
    aniline 12.14
    1,3-propanediol 133.0
    bromobenzene 3.46
    dibromomethane 16.59
    1,1,2,2-tetrachloroethane 23.03
    2-methyl-cyclohexyl acetate 4.93
    tetrabutyl urea 5.6
    diisobutyl methanol 2.56
    2-phenylethanol 10.24
    styrene 0.91
    dioctyl adipate 3.85
    dimethyl sulfate 15.15
    ethyl butyrate 6.83
    methyl lactate 21.34
    butyl lactate 11.27
    diethyl carbonate 5.27
    propanediol butyl ether 20.54
    triethyl orthoformate 5.56
    p-tert-butyltoluene 1.33
    methyl 4-tert-butylbenzoate 6.12
    morpholine 36.55
    tert-butylamine 8.46
    n-dodecanol 2.11
    dimethoxymethane 14.3
    ethylene carbonate 26.88
    cyrene 15.8
    2-ethoxyethyl acetate 7.18
    2-ethylhexyl acetate 5.23
    1,2,4-trichlorobenzene 8.17
    4-methylpyridine 12.31
    dibutyl ether 2.03
    2,6-dimethyl-4-heptanol 2.56
    DEF 15.3
    dimethyl isosorbide 16.55
    tetrachloroethylene 29.04
    eugenol 10.53
    triacetin 6.19
    span 80 15.57
    1,4-butanediol 43.59
    1,1-dichloroethane 7.38
    2-methyl-1-pentanol 7.03
    methyl formate 65.04
    2-methyl-1-butanol 18.95
    n-decane 0.38
    butyronitrile 14.48
    3,7-dimethyl-1-octanol 3.15
    1-chlorooctane 1.41
    1-chlorotetradecane 0.56
    n-nonane 0.39
    undecane 0.29
    tert-butylcyclohexane 0.29
    cyclooctane 0.32
    cyclopentanol 40.51
    tetrahydropyran 11.6
    tert-amyl methyl ether 2.45
    2,5,8-trioxanonane 17.26
    1-hexene 1.5
    2-isopropoxyethanol 11.56
    2,2,2-trifluoroethanol 116.46
    methyl butyrate 7.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction