Methyl phenoxyacetate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    2065-23-8

    Molecular formula
    C9H10O3

    SMILES
    COC(=O)COC1=CC=CC=C1

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 68.13%
    Honey 49.34%
    Floral 49.18%
    Sweet 47.89%
    Green 44.31%
    Caramellic 37.92%
    Rose 33.6%
    Nutty 32.35%
    Balsamic 30.17%
    Fatty 28.84%

     

    Flavor
    Fruity 73.27%
    Sweet 71.86%
    Floral 64.11%
    Balsam 56.74%
    Strawberry 37.34%
    Cherry 35.46%
    Honey 34.82%
    Plum 34.72%
    Rose 34.34%
    Berry 33.79%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    6.14 (neutral)

    Molecular weight
    166.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    234°C

    Flash point

    • 104.71 ˚C est.

  • Synonyms

    • methyl 2-phenoxyacetate
    • METHYL PHENOXYACETATE
    • 2065-23-8
    • Phenoxyacetic acid methyl ester
    • Acetic acid, phenoxy-, methyl ester
    • Acetic acid, 2-phenoxy-, methyl ester
    • JD9OF3328O
    • EINECS 218-176-4
    • NSC 32414
    • NSC-32414
    • AI3-04318
    • DTXSID2062161
    • RefChem:818034
    • DTXCID9036359
    • 218-176-4
    • InChI=1/C9H10O3/c1-11-9(10)7-12-8-5-3-2-4-6-8/h2-6H,7H2,1H
    • MFCD00010227
    • METHYLPHENOXYACETATE
    • UNII-JD9OF3328O
    • Methyl phenoxy acetate
    • Tafluprost Impurity 61
    • Methyl phenoxyacetate, 99%
    • SCHEMBL23295
    • SCHEMBL544051
    • SCHEMBL1387534
    • SCHEMBL2565533
    • SCHEMBL3169923
    • SCHEMBL4587997
    • SCHEMBL7050187
    • SCHEMBL7400285
    • phenoxy-acetic acid methyl ester
    • NSC32414
    • AKOS008904038
    • CS-W016060
    • DS-6675
    • EBC-151112
    • SY037886
    • DB-045321
    • NS00026708
    • P0110
    • ST50405262
    • D70332
    • EN300-250786
    • 065M238
    • F001024
    • Q27281453
    • Z18313678
    • 2065-23-8

  • Applications

    Methyl phenoxyacetate (CAS 2065-23-8) is used primarily as a fragrance ingredient and a synthetic building block in perfumery, serving as an aroma compound and a precursor for the preparation of other fragrant esters; in cosmetics and personal care, it is commonly used as a fragrance component to impart a light aromatic note; in household products such as detergents and cleaners, it may be included as a fragrance additive to improve scent profiles; in industrial manufacturing, it functions as an intermediate for the synthesis of fragrance-related esters and other specialty chemicals used in various formulation sectors.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 156.65
    methanol 222.63
    isopropanol 82.73
    water 1.74
    ethyl acetate 344.43
    n-propanol 98.58
    acetone 169.03
    n-butanol 76.86
    acetonitrile 322.81
    DMF 230.96
    toluene 70.15
    isobutanol 64.77
    1,4-dioxane 542.0
    methyl acetate 298.6
    THF 274.4
    2-butanone 163.8
    n-pentanol 60.53
    sec-butanol 91.17
    n-hexane 3.52
    ethylene glycol 86.77
    NMP 130.38
    cyclohexane 15.0
    DMSO 569.09
    n-butyl acetate 81.3
    n-octanol 23.56
    chloroform 451.31
    n-propyl acetate 109.84
    acetic acid 328.78
    dichloromethane 588.47
    cyclohexanone 154.28
    propylene glycol 71.75
    isopropyl acetate 92.31
    DMAc 307.67
    2-ethoxyethanol 243.45
    isopentanol 71.94
    n-heptane 4.81
    ethyl formate 144.68
    1,2-dichloroethane 397.53
    n-hexanol 45.46
    2-methoxyethanol 411.94
    isobutyl acetate 49.84
    tetrachloromethane 34.16
    n-pentyl acetate 32.72
    transcutol 749.59
    n-heptanol 20.96
    ethylbenzene 40.35
    MIBK 62.64
    2-propoxyethanol 118.89
    tert-butanol 196.26
    MTBE 123.85
    2-butoxyethanol 66.1
    propionic acid 155.4
    o-xylene 56.14
    formic acid 218.06
    diethyl ether 167.08
    m-xylene 38.46
    p-xylene 54.39
    chlorobenzene 101.86
    dimethyl carbonate 88.23
    n-octane 2.27
    formamide 487.52
    cyclopentanone 155.51
    2-pentanone 92.0
    anisole 135.73
    cyclopentyl methyl ether 91.28
    gamma-butyrolactone 267.92
    1-methoxy-2-propanol 178.8
    pyridine 345.24
    3-pentanone 94.91
    furfural 337.41
    n-dodecane 2.44
    diethylene glycol 152.09
    diisopropyl ether 25.63
    tert-amyl alcohol 149.2
    acetylacetone 182.02
    n-hexadecane 2.8
    acetophenone 115.73
    methyl propionate 180.66
    isopentyl acetate 69.98
    trichloroethylene 662.8
    n-nonanol 22.6
    cyclohexanol 82.49
    benzyl alcohol 102.8
    2-ethylhexanol 35.83
    isooctanol 20.0
    dipropyl ether 44.24
    1,2-dichlorobenzene 106.42
    ethyl lactate 59.66
    propylene carbonate 134.16
    n-methylformamide 190.02
    2-pentanol 49.98
    n-pentane 3.93
    1-propoxy-2-propanol 70.06
    1-methoxy-2-propyl acetate 98.27
    2-(2-methoxypropoxy) propanol 115.16
    mesitylene 25.09
    ε-caprolactone 155.38
    p-cymene 24.53
    epichlorohydrin 425.44
    1,1,1-trichloroethane 201.14
    2-aminoethanol 127.13
    morpholine-4-carbaldehyde 276.8
    sulfolane 271.57
    2,2,4-trimethylpentane 4.77
    2-methyltetrahydrofuran 173.79
    n-hexyl acetate 52.42
    isooctane 2.71
    2-(2-butoxyethoxy)ethanol 142.17
    sec-butyl acetate 65.42
    tert-butyl acetate 97.32
    decalin 8.17
    glycerin 144.5
    diglyme 351.6
    acrylic acid 161.6
    isopropyl myristate 25.34
    n-butyric acid 150.06
    acetyl acetate 181.67
    di(2-ethylhexyl) phthalate 30.36
    ethyl propionate 107.89
    nitromethane 719.72
    1,2-diethoxyethane 150.15
    benzonitrile 111.97
    trioctyl phosphate 17.65
    1-bromopropane 112.46
    gamma-valerolactone 250.57
    n-decanol 17.63
    triethyl phosphate 50.78
    4-methyl-2-pentanol 30.03
    propionitrile 162.36
    vinylene carbonate 149.9
    1,1,2-trichlorotrifluoroethane 306.75
    DMS 94.05
    cumene 26.54
    2-octanol 13.88
    2-hexanone 77.14
    octyl acetate 29.74
    limonene 33.67
    1,2-dimethoxyethane 356.26
    ethyl orthosilicate 47.01
    tributyl phosphate 28.07
    diacetone alcohol 124.46
    N,N-dimethylaniline 81.51
    acrylonitrile 231.66
    aniline 122.81
    1,3-propanediol 164.5
    bromobenzene 100.27
    dibromomethane 296.56
    1,1,2,2-tetrachloroethane 465.11
    2-methyl-cyclohexyl acetate 60.99
    tetrabutyl urea 38.17
    diisobutyl methanol 24.31
    2-phenylethanol 68.41
    styrene 58.49
    dioctyl adipate 53.14
    dimethyl sulfate 143.07
    ethyl butyrate 86.6
    methyl lactate 85.71
    butyl lactate 35.4
    diethyl carbonate 78.39
    propanediol butyl ether 66.07
    triethyl orthoformate 63.52
    p-tert-butyltoluene 22.33
    methyl 4-tert-butylbenzoate 74.43
    morpholine 491.34
    tert-butylamine 90.65
    n-dodecanol 14.7
    dimethoxymethane 202.45
    ethylene carbonate 117.81
    cyrene 99.08
    2-ethoxyethyl acetate 81.18
    2-ethylhexyl acetate 55.63
    1,2,4-trichlorobenzene 133.69
    4-methylpyridine 188.03
    dibutyl ether 41.61
    2,6-dimethyl-4-heptanol 24.31
    DEF 150.67
    dimethyl isosorbide 164.86
    tetrachloroethylene 286.38
    eugenol 79.28
    triacetin 96.55
    span 80 68.86
    1,4-butanediol 58.22
    1,1-dichloroethane 237.49
    2-methyl-1-pentanol 64.53
    methyl formate 161.87
    2-methyl-1-butanol 69.44
    n-decane 3.51
    butyronitrile 111.27
    3,7-dimethyl-1-octanol 30.87
    1-chlorooctane 17.38
    1-chlorotetradecane 8.05
    n-nonane 3.09
    undecane 2.85
    tert-butylcyclohexane 6.62
    cyclooctane 4.36
    cyclopentanol 65.58
    tetrahydropyran 233.35
    tert-amyl methyl ether 91.25
    2,5,8-trioxanonane 253.63
    1-hexene 19.87
    2-isopropoxyethanol 128.85
    2,2,2-trifluoroethanol 138.51
    methyl butyrate 133.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction