Methyl perfluoroisobutyl ether

Overview IFRA Request a quote

  • Identifiers

    CAS number
    163702-08-7

    Molecular formula
    C5H3F9O

    SMILES
    COC(C(C(F)(F)F)(C(F)(F)F)F)(F)F

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 46.0%
    Woody 29.7%
    Sweet 27.04%
    Cooling 24.25%
    Balsamic 21.57%
    Mint 18.52%
    Dry 18.33%
    Fishy 18.22%
    Earthy 17.89%
    Camphoreous 17.75%

     

    Flavor
    Odorless 31.74%
    Bland 23.73%
    Bitter 22.2%
    Sulfurous 20.89%
    Mild 18.6%
    Sweet-like 18.21%
    Bouillon 17.56%
    Bloody 17.43%
    Glue 17.33%
    Catty 17.21%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    6.25 (neutral)

    Molecular weight
    250.06 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    61°C

    Flash point

    • -0.73 ˚C est.

  • Synonyms

    • Methyl perfluoroisobutyl ether
    • 163702-08-7
    • perfluoroisobutyl methyl ether
    • Propane, 2-(difluoromethoxymethyl)-1,1,1,2,3,3,3-heptafluoro-
    • HI89P35AAX
    • methyl nonafluoroisobutyl ether
    • UNII-HI89P35AAX
    • DTXSID5042326
    • 1,1,2,3,3,3-HEXAFLUORO-1-METHOXY-2-(TRIFLUOROMETHYL)PROPANE
    • 2-(difluoromethoxymethyl)-1,1,1,2,3,3,3-heptafluoropropane
    • methylperfluorobutylether
    • RefChem:157993
    • DTXCID301020834
    • METHYL PERFLUOROISOBUTYL ETHER [INCI]
    • VF45 (TM) HFEBased Cleaning Fluid, VOL0570A
    • Propane, 2(difluoromethoxymethyl)1,1,1,2,3,3,3heptafluoro
    • 422-270-2
    • 605-340-9
    • 2-[difluoro(methoxy)methyl]-1,1,1,2,3,3,3-heptafluoropropane
    • 1,1,1,2,3,3-hexafluoro-3-methoxy-2-(trifluoromethyl)propane
    • 2-[Difluoro(methoxy)methyl]-1,1,1,2,3,3,3-heptafluoro-propane
    • 2-(difluoro(methoxy)methyl)-1,1,1,2,3,3,3-heptafluoropropane
    • (CF3)2CFCF2OCH3
    • SCHEMBL366639
    • methyl perfluoroisobutanyl ether
    • CHEMBL477673
    • MFCD01940779
    • MSK180928
    • AKOS040767511
    • AT43122
    • FH159793
    • DB-352148
    • Q27279946
    • 163702-08-7

  • Applications

    Applications of methyl perfluoroisobutyl ether (CAS 163702-08-7) include use as a high-purity solvent for electronics and precision cleaning (for example PCB assemblies and optical components); it is also employed as a processing solvent or co-solvent in fluorinated coatings and inks formulations; it can serve as a solvent or processing aid for fluoropolymers and fluorinated resins in polymer manufacturing; it has been evaluated as a heat-transfer fluid for specialized cooling applications in electronics and industrial equipment; and it can function as an intermediate in the synthesis of fluorinated materials or specialty chemicals. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 243.45
    methanol 375.85
    isopropanol 214.53
    water 7.86
    ethyl acetate 317.11
    n-propanol 173.46
    acetone 708.34
    n-butanol 192.43
    acetonitrile 463.28
    DMF 1339.34
    toluene 124.85
    isobutanol 150.69
    1,4-dioxane 313.04
    methyl acetate 340.74
    THF 1258.49
    2-butanone 432.79
    n-pentanol 136.94
    sec-butanol 180.54
    n-hexane 32.37
    ethylene glycol 107.89
    NMP 1203.36
    cyclohexane 34.15
    DMSO 2569.55
    n-butyl acetate 140.38
    n-octanol 63.54
    chloroform 267.41
    n-propyl acetate 185.92
    acetic acid 145.32
    dichloromethane 385.48
    cyclohexanone 348.95
    propylene glycol 114.0
    isopropyl acetate 216.52
    DMAc 1146.17
    2-ethoxyethanol 302.4
    isopentanol 185.73
    n-heptane 29.78
    ethyl formate 301.95
    1,2-dichloroethane 342.0
    n-hexanol 128.08
    2-methoxyethanol 640.94
    isobutyl acetate 86.61
    tetrachloromethane 57.47
    n-pentyl acetate 78.21
    transcutol 207.1
    n-heptanol 54.55
    ethylbenzene 81.37
    MIBK 258.67
    2-propoxyethanol 318.95
    tert-butanol 301.47
    MTBE 226.88
    2-butoxyethanol 116.89
    propionic acid 126.55
    o-xylene 109.43
    formic acid 163.91
    diethyl ether 298.13
    m-xylene 106.58
    p-xylene 88.91
    chlorobenzene 92.92
    dimethyl carbonate 256.97
    n-octane 13.56
    formamide 383.16
    cyclopentanone 632.64
    2-pentanone 426.98
    anisole 175.42
    cyclopentyl methyl ether 399.82
    gamma-butyrolactone 646.55
    1-methoxy-2-propanol 534.63
    pyridine 278.77
    3-pentanone 318.15
    furfural 467.07
    n-dodecane 11.61
    diethylene glycol 258.63
    diisopropyl ether 103.21
    tert-amyl alcohol 227.4
    acetylacetone 441.78
    n-hexadecane 12.73
    acetophenone 181.34
    methyl propionate 349.08
    isopentyl acetate 103.97
    trichloroethylene 371.01
    n-nonanol 60.65
    cyclohexanol 144.27
    benzyl alcohol 117.18
    2-ethylhexanol 77.22
    isooctanol 45.2
    dipropyl ether 141.35
    1,2-dichlorobenzene 97.03
    ethyl lactate 142.24
    propylene carbonate 283.68
    n-methylformamide 584.12
    2-pentanol 153.61
    n-pentane 40.66
    1-propoxy-2-propanol 194.49
    1-methoxy-2-propyl acetate 206.6
    2-(2-methoxypropoxy) propanol 140.42
    mesitylene 72.44
    ε-caprolactone 272.35
    p-cymene 56.27
    epichlorohydrin 695.22
    1,1,1-trichloroethane 219.91
    2-aminoethanol 150.03
    morpholine-4-carbaldehyde 576.77
    sulfolane 979.83
    2,2,4-trimethylpentane 19.69
    2-methyltetrahydrofuran 532.95
    n-hexyl acetate 103.0
    isooctane 16.77
    2-(2-butoxyethoxy)ethanol 137.81
    sec-butyl acetate 123.8
    tert-butyl acetate 230.56
    decalin 23.28
    glycerin 158.37
    diglyme 268.08
    acrylic acid 116.92
    isopropyl myristate 56.28
    n-butyric acid 169.79
    acetyl acetate 177.26
    di(2-ethylhexyl) phthalate 49.9
    ethyl propionate 232.65
    nitromethane 703.45
    1,2-diethoxyethane 137.1
    benzonitrile 132.81
    trioctyl phosphate 44.12
    1-bromopropane 226.38
    gamma-valerolactone 580.67
    n-decanol 50.03
    triethyl phosphate 91.12
    4-methyl-2-pentanol 106.97
    propionitrile 296.97
    vinylene carbonate 198.55
    1,1,2-trichlorotrifluoroethane 337.23
    DMS 129.64
    cumene 58.61
    2-octanol 45.22
    2-hexanone 236.19
    octyl acetate 69.8
    limonene 77.42
    1,2-dimethoxyethane 594.87
    ethyl orthosilicate 80.91
    tributyl phosphate 53.87
    diacetone alcohol 320.71
    N,N-dimethylaniline 169.53
    acrylonitrile 353.41
    aniline 131.42
    1,3-propanediol 207.14
    bromobenzene 95.15
    dibromomethane 296.03
    1,1,2,2-tetrachloroethane 325.79
    2-methyl-cyclohexyl acetate 98.28
    tetrabutyl urea 98.18
    diisobutyl methanol 61.63
    2-phenylethanol 111.1
    styrene 79.53
    dioctyl adipate 73.65
    dimethyl sulfate 433.91
    ethyl butyrate 148.12
    methyl lactate 266.48
    butyl lactate 74.06
    diethyl carbonate 98.3
    propanediol butyl ether 91.41
    triethyl orthoformate 93.67
    p-tert-butyltoluene 56.25
    methyl 4-tert-butylbenzoate 130.69
    morpholine 419.92
    tert-butylamine 164.9
    n-dodecanol 40.14
    dimethoxymethane 838.3
    ethylene carbonate 180.09
    cyrene 210.05
    2-ethoxyethyl acetate 101.04
    2-ethylhexyl acetate 85.7
    1,2,4-trichlorobenzene 107.14
    4-methylpyridine 305.75
    dibutyl ether 81.65
    2,6-dimethyl-4-heptanol 61.63
    DEF 483.52
    dimethyl isosorbide 272.38
    tetrachloroethylene 201.6
    eugenol 117.25
    triacetin 97.55
    span 80 80.24
    1,4-butanediol 99.11
    1,1-dichloroethane 237.37
    2-methyl-1-pentanol 124.15
    methyl formate 526.7
    2-methyl-1-butanol 166.57
    n-decane 17.51
    butyronitrile 275.2
    3,7-dimethyl-1-octanol 64.55
    1-chlorooctane 48.98
    1-chlorotetradecane 24.93
    n-nonane 16.67
    undecane 14.21
    tert-butylcyclohexane 20.63
    cyclooctane 19.17
    cyclopentanol 208.03
    tetrahydropyran 265.33
    tert-amyl methyl ether 222.28
    2,5,8-trioxanonane 214.23
    1-hexene 80.71
    2-isopropoxyethanol 187.92
    2,2,2-trifluoroethanol 110.4
    methyl butyrate 287.76

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction