Methyl (p-tolyloxy)acetate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    38768-63-7

    Molecular formula
    C10H12O3

    SMILES
    CC1=CC=C(C=C1)OCC(=O)OC

  • Odor profile

    Fragrance
    Fruity 78.58%
    Floral 43.36%
    Honey 35.46%
    Green 34.24%
    Fatty 32.81%
    Nutty 32.73%
    Sweet 31.77%
    Animal 30.96%
    Caramellic 30.05%
    Berry 26.47%

     

    Flavor
    Sweet 76.86%
    Fruity 68.21%
    Floral 62.25%
    Balsam 53.61%
    Powdery 42.25%
    Cherry 37.18%
    Vanilla 35.95%
    Herbal 35.26%
    Flower 35.25%
    Plum 33.56%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    6.83 (neutral)

    Molecular weight
    180.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    252°C

    Flash point

    • 105.71 ˚C est.

  • Synonyms

    • Methyl (p-tolyloxy)acetate
    • 38768-63-7
    • Methyl 2-(p-tolyloxy)acetate
    • methyl 2-(4-methylphenoxy)acetate
    • Methyl p-tolyloxyacetate
    • methyl(p-tolyloxy)acetate
    • methyl p-methylphenoxyacetate
    • SCHEMBL5111012
    • methyl (para-tolyl oxy) acetate
    • DTXSID90345114
    • Methyl (4-methylphenoxy)acetate #
    • Methyl (p-tolyloxy)acetate, >=98%
    • AKOS000295649

  • Applications

    Methyl (p-tolyloxy)acetate (CAS 38768-63-7) is primarily used as an intermediate in fragrance and specialty chemical synthesis; it serves as a building block for aryl-oxyacetate esters and related aroma compounds, helping to tailor odor profiles. In perfumery and cosmetics, it is commonly used as a fragrance intermediate or precursor to more complex scent ingredients. In coatings and inks, it may be used as a specialized intermediate to introduce the p-tolyloxy functionality into ester-based odorant formulations. In household and cleaning products, it can be used as a fragrance component or formulation precursor. In industrial manufacturing and polymer-related applications, it provides a route to complex esters and can be evaluated as a reactive intermediate or functional monomer precursor for certain resin systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 452.35
    methanol 587.18
    isopropanol 254.14
    water 3.96
    ethyl acetate 521.0
    n-propanol 275.47
    acetone 134.66
    n-butanol 202.43
    acetonitrile 295.56
    DMF 203.73
    toluene 72.12
    isobutanol 142.33
    1,4-dioxane 869.88
    methyl acetate 392.25
    THF 280.31
    2-butanone 175.68
    n-pentanol 128.71
    sec-butanol 196.85
    n-hexane 1.39
    ethylene glycol 219.74
    NMP 63.7
    cyclohexane 6.51
    DMSO 322.91
    n-butyl acetate 75.36
    n-octanol 27.2
    chloroform 359.53
    n-propyl acetate 107.63
    acetic acid 393.28
    dichloromethane 398.63
    cyclohexanone 127.54
    propylene glycol 243.74
    isopropyl acetate 128.06
    DMAc 287.61
    2-ethoxyethanol 518.72
    isopentanol 139.81
    n-heptane 2.51
    ethyl formate 201.69
    1,2-dichloroethane 253.25
    n-hexanol 77.11
    2-methoxyethanol 1012.43
    isobutyl acetate 48.36
    tetrachloromethane 25.53
    n-pentyl acetate 29.57
    transcutol 796.19
    n-heptanol 29.7
    ethylbenzene 36.78
    MIBK 61.84
    2-propoxyethanol 234.72
    tert-butanol 402.05
    MTBE 148.68
    2-butoxyethanol 96.95
    propionic acid 229.06
    o-xylene 53.42
    formic acid 357.48
    diethyl ether 175.23
    m-xylene 41.77
    p-xylene 47.89
    chlorobenzene 84.99
    dimethyl carbonate 97.44
    n-octane 1.42
    formamide 710.12
    cyclopentanone 101.65
    2-pentanone 105.17
    anisole 153.69
    cyclopentyl methyl ether 84.09
    gamma-butyrolactone 205.8
    1-methoxy-2-propanol 452.23
    pyridine 329.9
    3-pentanone 83.43
    furfural 288.33
    n-dodecane 1.86
    diethylene glycol 306.35
    diisopropyl ether 24.34
    tert-amyl alcohol 257.85
    acetylacetone 176.43
    n-hexadecane 2.1
    acetophenone 113.35
    methyl propionate 246.91
    isopentyl acetate 66.35
    trichloroethylene 446.68
    n-nonanol 26.75
    cyclohexanol 128.59
    benzyl alcohol 152.37
    2-ethylhexanol 40.45
    isooctanol 24.59
    dipropyl ether 36.52
    1,2-dichlorobenzene 79.15
    ethyl lactate 67.75
    propylene carbonate 117.27
    n-methylformamide 248.67
    2-pentanol 103.92
    n-pentane 1.97
    1-propoxy-2-propanol 116.18
    1-methoxy-2-propyl acetate 121.38
    2-(2-methoxypropoxy) propanol 124.28
    mesitylene 22.6
    ε-caprolactone 158.93
    p-cymene 19.74
    epichlorohydrin 402.62
    1,1,1-trichloroethane 151.63
    2-aminoethanol 388.43
    morpholine-4-carbaldehyde 308.96
    sulfolane 144.83
    2,2,4-trimethylpentane 3.1
    2-methyltetrahydrofuran 197.71
    n-hexyl acetate 47.75
    isooctane 1.99
    2-(2-butoxyethoxy)ethanol 178.36
    sec-butyl acetate 66.18
    tert-butyl acetate 112.08
    decalin 4.62
    glycerin 351.55
    diglyme 365.51
    acrylic acid 193.49
    isopropyl myristate 21.59
    n-butyric acid 276.93
    acetyl acetate 196.07
    di(2-ethylhexyl) phthalate 28.84
    ethyl propionate 114.38
    nitromethane 650.52
    1,2-diethoxyethane 158.67
    benzonitrile 101.38
    trioctyl phosphate 15.88
    1-bromopropane 74.67
    gamma-valerolactone 280.87
    n-decanol 21.17
    triethyl phosphate 41.88
    4-methyl-2-pentanol 47.88
    propionitrile 177.97
    vinylene carbonate 136.92
    1,1,2-trichlorotrifluoroethane 298.85
    DMS 83.26
    cumene 23.94
    2-octanol 16.94
    2-hexanone 62.9
    octyl acetate 26.59
    limonene 25.29
    1,2-dimethoxyethane 491.71
    ethyl orthosilicate 41.62
    tributyl phosphate 23.05
    diacetone alcohol 167.93
    N,N-dimethylaniline 77.38
    acrylonitrile 238.21
    aniline 165.18
    1,3-propanediol 496.32
    bromobenzene 74.47
    dibromomethane 193.36
    1,1,2,2-tetrachloroethane 348.75
    2-methyl-cyclohexyl acetate 54.48
    tetrabutyl urea 30.99
    diisobutyl methanol 24.45
    2-phenylethanol 99.08
    styrene 49.98
    dioctyl adipate 43.52
    dimethyl sulfate 114.43
    ethyl butyrate 73.16
    methyl lactate 132.53
    butyl lactate 35.82
    diethyl carbonate 66.41
    propanediol butyl ether 90.49
    triethyl orthoformate 54.73
    p-tert-butyltoluene 19.56
    methyl 4-tert-butylbenzoate 67.84
    morpholine 864.61
    tert-butylamine 149.81
    n-dodecanol 17.42
    dimethoxymethane 287.47
    ethylene carbonate 117.67
    cyrene 98.76
    2-ethoxyethyl acetate 86.73
    2-ethylhexyl acetate 47.87
    1,2,4-trichlorobenzene 101.6
    4-methylpyridine 209.67
    dibutyl ether 33.28
    2,6-dimethyl-4-heptanol 24.45
    DEF 157.66
    dimethyl isosorbide 168.62
    tetrachloroethylene 198.02
    eugenol 82.23
    triacetin 79.11
    span 80 73.76
    1,4-butanediol 155.18
    1,1-dichloroethane 183.25
    2-methyl-1-pentanol 100.3
    methyl formate 188.97
    2-methyl-1-butanol 126.29
    n-decane 2.63
    butyronitrile 130.57
    3,7-dimethyl-1-octanol 34.78
    1-chlorooctane 13.78
    1-chlorotetradecane 6.8
    n-nonane 2.11
    undecane 2.15
    tert-butylcyclohexane 4.38
    cyclooctane 2.15
    cyclopentanol 98.52
    tetrahydropyran 286.87
    tert-amyl methyl ether 101.29
    2,5,8-trioxanonane 279.46
    1-hexene 11.8
    2-isopropoxyethanol 234.05
    2,2,2-trifluoroethanol 148.34
    methyl butyrate 138.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction