Methyl (methylsulfinyl)methyl sulfide

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  • Identifiers

    CAS number
    33577-16-1

    Molecular formula
    C3H8OS2

    SMILES
    CSCS(=O)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sulfurous 74.03%
    Onion 72.1%
    Garlic 68.11%
    Alliaceous 56.83%
    Vegetable 54.19%
    Cabbage 49.65%
    Pungent 46.79%
    Cooked 46.65%
    Meaty 45.13%
    Savory 44.66%

     

    Flavor
    Garlic 68.13%
    Onion 65.99%
    Sulfurous 64.23%
    Vegetable 48.75%
    Sulfur 47.99%
    Cabbage 45.23%
    Meaty 42.19%
    Alliaceous 41.9%
    Sulfury 41.36%
    Mushroom 37.68%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.1

    pKa est.
    7.24 (neutral)

    Molecular weight
    124.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    252°C

    Flash point

    • 111.65 ˚C est.

  • Synonyms

    • 33577-16-1
    • Methyl (methylsulfinyl)methyl sulfide
    • FAMSO
    • Methanesulfinyl-methylsulfanyl-methane
    • Methane, (methylsulfinyl)(methylthio)-
    • Methyl((methylsulfinyl)methyl)sulfane
    • (Methylsulfinyl)(methylthio)methane
    • methylsulfanyl(methylsulfinyl)methane
    • Formaldehyde dimethyl mercaptal S-oxide
    • Methyl (methylthio)methyl sulfoxide
    • Methyl methylthiomethyl sulfoxide
    • Methyl methylthiomethyl sulphoxide
    • Formaldehyde methyl mercaptal S-oxide
    • Sulfide, methyl (methylsulfinyl)methyl
    • (Methylthio)dimethyl sulfoxide
    • MFCD00002091
    • NSC 181492
    • Methylsulfinyl(methylthio)methane
    • EINECS 251-577-2
    • Methyl methylmercaptomethyl sulfoxide
    • SCHEMBL364365
    • SCHEMBL10633027
    • DTXSID00865676
    • methylsulfinyl (methylthio)methane
    • Methylsulfinylmethylsulfanylmethane
    • CHEBI:167080
    • methylsulanyl(methylsulinyl)methane
    • methyl (methylthiomethyl)sulphoxide
    • methyl (methylthiomethyl) sulphoxide
    • methyl methylsulfinyl-methyl sulfide
    • methyl methylsulphinylmethyl sulphide
    • EBC-48042
    • methanesulfinyl(methylsulfanyl)methane
    • NSC181492
    • AKOS000278611
    • (Methylsulfanyl)(methylsulfinyl)methane
    • NSC-181492
    • (Methanesulfinyl)(methylsulfanyl)methane
    • AS-55805
    • BP-12695
    • SY049552
    • Formaldehyde Dimethyl Dithioacetal S-Oxide
    • DB-026948
    • CS-0146450
    • M0805
    • NS00054720
    • A23492
    • F303199
    • F0001-2719
    • Z1255438413
    • (Methylsulfanyl)(methylsulfinyl)methane;(methylsulfinyl)(methylthio)-methan
    • 33577-16-1

  • Applications

    Methyl (methylsulfinyl)methyl sulfide (CAS 33577-16-1) is mainly used as an intermediate in the synthesis of sulfur-containing compounds for industrial production. It may function as a fragrance/odorant ingredient or fixative in perfumery, and can be considered a precursor or aroma component in fragrance formulations. In cosmetics and personal care, it is evaluated as a fragrance ingredient. It may also serve as a processing aid or a specialty additive in coatings and inks, as well as in household products to impart or stabilize odor characteristics. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 622.3
    methanol 1049.84
    isopropanol 357.04
    water 127.96
    ethyl acetate 228.4
    n-propanol 404.44
    acetone 636.01
    n-butanol 282.12
    acetonitrile 450.78
    DMF 781.02
    toluene 158.74
    isobutanol 229.09
    1,4-dioxane 625.41
    methyl acetate 291.27
    THF 793.58
    2-butanone 341.95
    n-pentanol 183.62
    sec-butanol 262.62
    n-hexane 60.44
    ethylene glycol 434.77
    NMP 892.4
    cyclohexane 155.86
    DMSO 783.1
    n-butyl acetate 179.02
    n-octanol 162.55
    chloroform 563.62
    n-propyl acetate 146.92
    acetic acid 905.91
    dichloromethane 455.75
    cyclohexanone 554.75
    propylene glycol 305.68
    isopropyl acetate 121.09
    DMAc 497.17
    2-ethoxyethanol 337.03
    isopentanol 166.81
    n-heptane 76.91
    ethyl formate 207.4
    1,2-dichloroethane 295.78
    n-hexanol 253.63
    2-methoxyethanol 671.04
    isobutyl acetate 87.87
    tetrachloromethane 146.26
    n-pentyl acetate 134.94
    transcutol 925.31
    n-heptanol 130.53
    ethylbenzene 74.07
    MIBK 126.68
    2-propoxyethanol 435.59
    tert-butanol 318.96
    MTBE 169.1
    2-butoxyethanol 228.81
    propionic acid 405.39
    o-xylene 124.95
    formic acid 631.71
    diethyl ether 269.34
    m-xylene 124.3
    p-xylene 94.39
    chlorobenzene 180.08
    dimethyl carbonate 104.48
    n-octane 25.06
    formamide 598.61
    cyclopentanone 634.86
    2-pentanone 240.81
    anisole 171.54
    cyclopentyl methyl ether 359.29
    gamma-butyrolactone 641.9
    1-methoxy-2-propanol 413.76
    pyridine 399.49
    3-pentanone 219.99
    furfural 600.4
    n-dodecane 20.55
    diethylene glycol 467.39
    diisopropyl ether 70.73
    tert-amyl alcohol 232.57
    acetylacetone 288.05
    n-hexadecane 22.47
    acetophenone 184.35
    methyl propionate 223.73
    isopentyl acetate 136.86
    trichloroethylene 501.17
    n-nonanol 139.38
    cyclohexanol 368.84
    benzyl alcohol 169.45
    2-ethylhexanol 147.74
    isooctanol 94.45
    dipropyl ether 182.23
    1,2-dichlorobenzene 180.25
    ethyl lactate 113.76
    propylene carbonate 286.96
    n-methylformamide 527.02
    2-pentanol 174.71
    n-pentane 74.39
    1-propoxy-2-propanol 313.13
    1-methoxy-2-propyl acetate 207.22
    2-(2-methoxypropoxy) propanol 256.12
    mesitylene 86.19
    ε-caprolactone 395.37
    p-cymene 79.97
    epichlorohydrin 462.06
    1,1,1-trichloroethane 259.9
    2-aminoethanol 461.22
    morpholine-4-carbaldehyde 796.79
    sulfolane 730.44
    2,2,4-trimethylpentane 26.06
    2-methyltetrahydrofuran 483.77
    n-hexyl acetate 202.81
    isooctane 18.13
    2-(2-butoxyethoxy)ethanol 333.84
    sec-butyl acetate 84.25
    tert-butyl acetate 135.26
    decalin 43.61
    glycerin 454.7
    diglyme 520.46
    acrylic acid 441.06
    isopropyl myristate 93.23
    n-butyric acid 356.62
    acetyl acetate 171.68
    di(2-ethylhexyl) phthalate 107.15
    ethyl propionate 128.66
    nitromethane 891.38
    1,2-diethoxyethane 241.01
    benzonitrile 229.41
    trioctyl phosphate 79.41
    1-bromopropane 177.5
    gamma-valerolactone 754.16
    n-decanol 104.6
    triethyl phosphate 88.41
    4-methyl-2-pentanol 82.58
    propionitrile 251.01
    vinylene carbonate 294.08
    1,1,2-trichlorotrifluoroethane 464.51
    DMS 170.47
    cumene 60.35
    2-octanol 95.07
    2-hexanone 168.11
    octyl acetate 124.06
    limonene 140.89
    1,2-dimethoxyethane 436.59
    ethyl orthosilicate 88.38
    tributyl phosphate 94.73
    diacetone alcohol 204.99
    N,N-dimethylaniline 143.9
    acrylonitrile 332.35
    aniline 242.31
    1,3-propanediol 405.33
    bromobenzene 154.29
    dibromomethane 337.03
    1,1,2,2-tetrachloroethane 407.36
    2-methyl-cyclohexyl acetate 144.33
    tetrabutyl urea 144.79
    diisobutyl methanol 86.37
    2-phenylethanol 193.99
    styrene 92.43
    dioctyl adipate 147.26
    dimethyl sulfate 180.71
    ethyl butyrate 134.79
    methyl lactate 182.4
    butyl lactate 139.87
    diethyl carbonate 91.16
    propanediol butyl ether 267.73
    triethyl orthoformate 117.55
    p-tert-butyltoluene 80.63
    methyl 4-tert-butylbenzoate 191.97
    morpholine 675.38
    tert-butylamine 219.68
    n-dodecanol 84.42
    dimethoxymethane 353.5
    ethylene carbonate 234.1
    cyrene 243.58
    2-ethoxyethyl acetate 180.85
    2-ethylhexyl acetate 114.14
    1,2,4-trichlorobenzene 226.6
    4-methylpyridine 328.01
    dibutyl ether 145.97
    2,6-dimethyl-4-heptanol 86.37
    DEF 295.86
    dimethyl isosorbide 387.4
    tetrachloroethylene 350.4
    eugenol 221.3
    triacetin 227.41
    span 80 269.35
    1,4-butanediol 181.6
    1,1-dichloroethane 269.56
    2-methyl-1-pentanol 127.42
    methyl formate 367.82
    2-methyl-1-butanol 179.87
    n-decane 34.2
    butyronitrile 214.33
    3,7-dimethyl-1-octanol 132.82
    1-chlorooctane 98.01
    1-chlorotetradecane 45.03
    n-nonane 35.46
    undecane 25.24
    tert-butylcyclohexane 35.59
    cyclooctane 47.41
    cyclopentanol 439.43
    tetrahydropyran 529.96
    tert-amyl methyl ether 148.17
    2,5,8-trioxanonane 413.64
    1-hexene 121.37
    2-isopropoxyethanol 207.07
    2,2,2-trifluoroethanol 347.39
    methyl butyrate 166.01

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction