Methyl 3-methoxypropionate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    3852-09-3

    Molecular formula
    C5H10O3

    SMILES
    COCCC(=O)OC

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fruity 93.18%
    Ethereal 82.31%
    Sweet 71.8%
    Rummy 61.98%
    Apple 54.64%
    Winey 53.68%
    Green 46.3%
    Fresh 45.16%
    Pineapple 41.27%
    Banana 39.89%

     

    Flavor
    Fruity 84.41%
    Sweet 76.57%
    Bitter 54.73%
    Pineapple 54.14%
    Green 52.12%
    Apple 47.54%
    Ether 42.49%
    Fruit 40.41%
    Banana 40.27%
    Rum 35.98%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    -0.1

    pKa est.
    6.64 (neutral)

    Molecular weight
    118.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    147°C

    Flash point

    • 38.96 ˚C est.

  • Synonyms

    • Methyl 3-methoxypropionate
    • 3852-09-3
    • Methyl 3-methoxypropanoate
    • 3-Methoxypropionic acid methyl ester
    • Propanoic acid, 3-methoxy-, methyl ester
    • Methyl beta-methoxypropionate
    • Methyl .beta.-methoxypropionate
    • 3-methoxypropanoic acid methyl ester
    • RL3A396XRV
    • NSC 65578
    • PROPIONIC ACID, 3-METHOXY-, METHYL ESTER
    • beta-Methoxypropionic acid, methyl ester
    • DTXSID3052060
    • EINECS 223-358-1
    • NSC-65578
    • BRN 1744829
    • Methylester kyseliny 3-methoxypropionove
    • Propanoic acid, 3-methoxy-, methyl ether
    • AI3-15733
    • DTXCID4030627
    • Methylester kyseliny 3-methoxypropionove [Czech]
    • 4-03-00-00693 (Beilstein Handbook Reference)
    • RefChem:815551
    • 223-358-1
    • MFCD00059085
    • Methyl methoxypropionate
    • 3-methoxy-propionic acid methyl ester
    • Methyl3-methoxypropionate
    • UNII-RL3A396XRV
    • methyl 3-methoxy-propionate
    • Propanoic acid, methyl ether
    • SCHEMBL27522
    • SCHEMBL5116131
    • CHEMBL3561708
    • SCHEMBL10665150
    • SCHEMBL20163316
    • SCHEMBL27645663
    • NSC65578
    • Tox21_304047
    • Methyl 3-methoxypropionate, >=99%
    • STL190840
    • 3-methoxy-propanoic acid methyl ester
    • AKOS009031415
    • Methyl ester of 3-methoxypropanoic acid
    • Methyl ester of 3-methoxypropionic acid
    • NCGC00357254-01
    • .beta.-Methoxypropionic acid, methyl ester
    • CAS-3852-09-3
    • CS-0072438
    • M0962
    • NS00019979
    • EN300-20228
    • E75736
    • F349308
    • Q27288167
    • F0001-1096
    • InChI=1/C5H10O3/c1-7-4-3-5(6)8-2/h3-4H2,1-2H
    • 3852-09-3

  • Applications

    Methyl 3-methoxypropionate (CAS 3852-09-3) is a polar, moderate-volatility solvent used across coatings, inks and adhesives as a versatile processing solvent; it also serves as a processing solvent for polymer and plastics formulations, providing thinning and resin compatibility; in industrial cleaning formulations, it is employed in degreasers and equipment cleaners; in electronics-related manufacturing, it may be used for specialty resin formulations and surface cleaning; and it can function as a chemical intermediate for the synthesis of other specialty esters, with use governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1838.27
    methanol 2978.17
    isopropanol 1126.83
    water 230.98
    ethyl acetate 328.77
    n-propanol 938.61
    acetone 510.27
    n-butanol 719.14
    acetonitrile 835.97
    DMF 1705.58
    toluene 200.93
    isobutanol 529.02
    1,4-dioxane 1486.04
    methyl acetate 517.6
    THF 828.2
    2-butanone 327.09
    n-pentanol 352.01
    sec-butanol 638.07
    n-hexane 24.14
    ethylene glycol 880.66
    NMP 761.57
    cyclohexane 108.87
    DMSO 1079.55
    n-butyl acetate 66.79
    n-octanol 93.89
    chloroform 1435.52
    n-propyl acetate 97.62
    acetic acid 1586.94
    dichloromethane 1241.37
    cyclohexanone 369.22
    propylene glycol 711.36
    isopropyl acetate 112.14
    DMAc 1257.85
    2-ethoxyethanol 772.36
    isopentanol 357.88
    n-heptane 21.83
    ethyl formate 484.86
    1,2-dichloroethane 497.73
    n-hexanol 191.66
    2-methoxyethanol 2022.48
    isobutyl acetate 49.13
    tetrachloromethane 273.73
    n-pentyl acetate 52.0
    transcutol 559.31
    n-heptanol 88.12
    ethylbenzene 73.04
    MIBK 74.56
    2-propoxyethanol 396.14
    tert-butanol 856.56
    MTBE 291.33
    2-butoxyethanol 189.34
    propionic acid 716.42
    o-xylene 140.75
    formic acid 1686.16
    diethyl ether 345.12
    m-xylene 99.69
    p-xylene 107.12
    chlorobenzene 224.93
    dimethyl carbonate 135.76
    n-octane 8.27
    formamide 1526.23
    cyclopentanone 356.7
    2-pentanone 180.73
    anisole 208.46
    cyclopentyl methyl ether 259.87
    gamma-butyrolactone 498.7
    1-methoxy-2-propanol 910.43
    pyridine 863.6
    3-pentanone 149.85
    furfural 710.65
    n-dodecane 7.89
    diethylene glycol 501.98
    diisopropyl ether 41.95
    tert-amyl alcohol 537.43
    acetylacetone 174.74
    n-hexadecane 8.63
    acetophenone 150.73
    methyl propionate 280.69
    isopentyl acetate 54.43
    trichloroethylene 906.92
    n-nonanol 83.67
    cyclohexanol 562.49
    benzyl alcohol 320.29
    2-ethylhexanol 83.19
    isooctanol 57.92
    dipropyl ether 82.63
    1,2-dichlorobenzene 163.65
    ethyl lactate 105.74
    propylene carbonate 239.16
    n-methylformamide 1184.21
    2-pentanol 285.43
    n-pentane 44.46
    1-propoxy-2-propanol 198.13
    1-methoxy-2-propyl acetate 93.31
    2-(2-methoxypropoxy) propanol 146.09
    mesitylene 52.7
    ε-caprolactone 349.69
    p-cymene 34.92
    epichlorohydrin 638.56
    1,1,1-trichloroethane 438.57
    2-aminoethanol 1252.97
    morpholine-4-carbaldehyde 1060.32
    sulfolane 389.64
    2,2,4-trimethylpentane 18.77
    2-methyltetrahydrofuran 556.92
    n-hexyl acetate 82.75
    isooctane 8.44
    2-(2-butoxyethoxy)ethanol 210.45
    sec-butyl acetate 56.09
    tert-butyl acetate 83.99
    decalin 24.51
    glycerin 935.2
    diglyme 424.33
    acrylic acid 686.44
    isopropyl myristate 31.5
    n-butyric acid 616.48
    acetyl acetate 189.53
    di(2-ethylhexyl) phthalate 45.74
    ethyl propionate 108.61
    nitromethane 1491.12
    1,2-diethoxyethane 138.9
    benzonitrile 265.76
    trioctyl phosphate 28.57
    1-bromopropane 295.14
    gamma-valerolactone 729.16
    n-decanol 58.75
    triethyl phosphate 49.7
    4-methyl-2-pentanol 93.38
    propionitrile 509.91
    vinylene carbonate 316.94
    1,1,2-trichlorotrifluoroethane 832.09
    DMS 77.68
    cumene 44.63
    2-octanol 49.8
    2-hexanone 89.34
    octyl acetate 47.38
    limonene 59.06
    1,2-dimethoxyethane 881.84
    ethyl orthosilicate 50.17
    tributyl phosphate 32.06
    diacetone alcohol 182.15
    N,N-dimethylaniline 138.32
    acrylonitrile 642.33
    aniline 519.11
    1,3-propanediol 1265.37
    bromobenzene 188.8
    dibromomethane 657.43
    1,1,2,2-tetrachloroethane 734.24
    2-methyl-cyclohexyl acetate 55.24
    tetrabutyl urea 52.83
    diisobutyl methanol 43.39
    2-phenylethanol 155.92
    styrene 112.31
    dioctyl adipate 57.19
    dimethyl sulfate 194.72
    ethyl butyrate 71.95
    methyl lactate 244.68
    butyl lactate 58.98
    diethyl carbonate 62.37
    propanediol butyl ether 169.04
    triethyl orthoformate 66.22
    p-tert-butyltoluene 36.31
    methyl 4-tert-butylbenzoate 99.1
    morpholine 1932.88
    tert-butylamine 481.26
    n-dodecanol 44.97
    dimethoxymethane 598.12
    ethylene carbonate 242.12
    cyrene 167.3
    2-ethoxyethyl acetate 84.67
    2-ethylhexyl acetate 41.8
    1,2,4-trichlorobenzene 220.46
    4-methylpyridine 664.81
    dibutyl ether 65.1
    2,6-dimethyl-4-heptanol 43.39
    DEF 464.1
    dimethyl isosorbide 159.24
    tetrachloroethylene 584.67
    eugenol 126.02
    triacetin 99.03
    span 80 135.67
    1,4-butanediol 428.8
    1,1-dichloroethane 567.02
    2-methyl-1-pentanol 209.12
    methyl formate 685.64
    2-methyl-1-butanol 395.49
    n-decane 13.14
    butyronitrile 508.8
    3,7-dimethyl-1-octanol 77.48
    1-chlorooctane 43.38
    1-chlorotetradecane 18.83
    n-nonane 12.7
    undecane 9.58
    tert-butylcyclohexane 18.84
    cyclooctane 22.48
    cyclopentanol 565.21
    tetrahydropyran 789.44
    tert-amyl methyl ether 196.1
    2,5,8-trioxanonane 283.75
    1-hexene 83.64
    2-isopropoxyethanol 323.61
    2,2,2-trifluoroethanol 604.75
    methyl butyrate 162.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction