Methyl 2-methylglycerate

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  • Identifiers

    CAS number
    19860-56-1

    Molecular formula
    C5H10O4

    SMILES
    CC(CO)(C(=O)OC)O

    Safety labels

  • Odor profile

    Fragrance
    Caramellic 65.9%
    Buttery 58.78%
    Fruity 52.79%
    Sweet 50.04%
    Milky 38.1%
    Creamy 35.98%
    Ethereal 33.12%
    Winey 28.7%
    Odorless 28.38%
    Dairy 27.84%

     

    Flavor
    Fruity 64.94%
    Creamy 40.18%
    Sweet 38.53%
    Odorless 34.24%
    Bitter 33.98%
    Buttery 32.66%
    Mild 30.93%
    Fruit 27.17%
    Waxy 25.38%
    Musty 24.8%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.0

    pKa est.
    6.91 (neutral)

    Molecular weight
    134.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    215°C

    Flash point

    • 96.02 ˚C est.

  • Synonyms

    • Methyl 2-methylglycerate
    • 19860-56-1
    • 2-Methylglyceric acid methyl ester
    • RefChem:157363
    • methyl 2,3-dihydroxy-2-methylpropanoate
    • SCHEMBL1964305
    • DTXSID70941698
    • AKOS013795042
    • DA-20682
    • Propanoic acid, 2,3-dihydroxy-2-methyl-, methyl ester
    • 19860-56-1

  • Applications

    Methyl 2-methylglycerate (CAS 19860-56-1) is primarily used as a chemical building block in organic synthesis and as an intermediate in the manufacture of pharmaceutical and agrochemical compounds. It can serve as a chiral precursor for ester and amino-alcohol derivatives, and may be employed as a fragrance ingredient or odorant in perfumery. In cosmetics and personal care formulations, it may function as a functional ingredient or co-solvent. It can also be used in coatings and inks as a reactive diluent or processing aid, and in the polymers/plastics sector as a building block for specialty polymers or as a linkage modifier. Use is typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 819.1
    methanol 1746.97
    isopropanol 476.42
    water 1103.55
    ethyl acetate 97.15
    n-propanol 484.39
    acetone 279.34
    n-butanol 349.2
    acetonitrile 157.12
    DMF 1294.78
    toluene 14.11
    isobutanol 283.58
    1,4-dioxane 383.96
    methyl acetate 118.04
    THF 391.53
    2-butanone 147.46
    n-pentanol 193.83
    sec-butanol 325.09
    n-hexane 7.78
    ethylene glycol 1104.89
    NMP 453.08
    cyclohexane 10.4
    DMSO 1282.49
    n-butyl acetate 29.58
    n-octanol 66.74
    chloroform 87.58
    n-propyl acetate 52.28
    acetic acid 785.82
    dichloromethane 119.29
    cyclohexanone 139.24
    propylene glycol 677.79
    isopropyl acetate 60.82
    DMAc 536.16
    2-ethoxyethanol 733.22
    isopentanol 217.29
    n-heptane 8.4
    ethyl formate 171.34
    1,2-dichloroethane 95.32
    n-hexanol 104.84
    2-methoxyethanol 1386.81
    isobutyl acetate 26.88
    tetrachloromethane 26.65
    n-pentyl acetate 32.53
    transcutol 393.04
    n-heptanol 69.78
    ethylbenzene 13.36
    MIBK 99.33
    2-propoxyethanol 329.58
    tert-butanol 549.46
    MTBE 160.54
    2-butoxyethanol 175.06
    propionic acid 270.28
    o-xylene 22.92
    formic acid 2054.37
    diethyl ether 133.27
    m-xylene 19.82
    p-xylene 14.67
    chlorobenzene 18.88
    dimethyl carbonate 79.66
    n-octane 4.16
    formamide 1473.36
    cyclopentanone 208.18
    2-pentanone 141.85
    anisole 58.27
    cyclopentyl methyl ether 125.88
    gamma-butyrolactone 252.71
    1-methoxy-2-propanol 682.37
    pyridine 78.33
    3-pentanone 83.28
    furfural 264.52
    n-dodecane 3.3
    diethylene glycol 559.18
    diisopropyl ether 37.3
    tert-amyl alcohol 356.49
    acetylacetone 152.83
    n-hexadecane 3.39
    acetophenone 62.61
    methyl propionate 121.13
    isopentyl acetate 31.41
    trichloroethylene 128.42
    n-nonanol 53.7
    cyclohexanol 164.16
    benzyl alcohol 101.93
    2-ethylhexanol 46.7
    isooctanol 53.48
    dipropyl ether 40.25
    1,2-dichlorobenzene 25.9
    ethyl lactate 92.21
    propylene carbonate 102.13
    n-methylformamide 803.68
    2-pentanol 192.18
    n-pentane 12.92
    1-propoxy-2-propanol 150.65
    1-methoxy-2-propyl acetate 66.47
    2-(2-methoxypropoxy) propanol 127.3
    mesitylene 18.18
    ε-caprolactone 134.34
    p-cymene 14.57
    epichlorohydrin 273.66
    1,1,1-trichloroethane 44.45
    2-aminoethanol 1107.93
    morpholine-4-carbaldehyde 546.95
    sulfolane 404.56
    2,2,4-trimethylpentane 11.33
    2-methyltetrahydrofuran 192.34
    n-hexyl acetate 52.14
    isooctane 8.44
    2-(2-butoxyethoxy)ethanol 169.07
    sec-butyl acetate 31.79
    tert-butyl acetate 91.5
    decalin 6.33
    glycerin 1098.86
    diglyme 324.28
    acrylic acid 301.92
    isopropyl myristate 21.47
    n-butyric acid 247.65
    acetyl acetate 52.24
    di(2-ethylhexyl) phthalate 32.28
    ethyl propionate 55.13
    nitromethane 747.45
    1,2-diethoxyethane 64.08
    benzonitrile 45.31
    trioctyl phosphate 28.41
    1-bromopropane 40.87
    gamma-valerolactone 371.52
    n-decanol 38.19
    triethyl phosphate 27.62
    4-methyl-2-pentanol 103.42
    propionitrile 99.26
    vinylene carbonate 101.57
    1,1,2-trichlorotrifluoroethane 384.16
    DMS 40.07
    cumene 14.13
    2-octanol 40.9
    2-hexanone 63.07
    octyl acetate 31.33
    limonene 23.07
    1,2-dimethoxyethane 493.38
    ethyl orthosilicate 27.61
    tributyl phosphate 25.16
    diacetone alcohol 240.75
    N,N-dimethylaniline 59.01
    acrylonitrile 135.45
    aniline 56.92
    1,3-propanediol 951.69
    bromobenzene 13.23
    dibromomethane 64.33
    1,1,2,2-tetrachloroethane 119.08
    2-methyl-cyclohexyl acetate 34.82
    tetrabutyl urea 41.26
    diisobutyl methanol 37.34
    2-phenylethanol 63.29
    styrene 13.49
    dioctyl adipate 35.21
    dimethyl sulfate 177.92
    ethyl butyrate 35.16
    methyl lactate 190.88
    butyl lactate 51.67
    diethyl carbonate 22.47
    propanediol butyl ether 171.16
    triethyl orthoformate 31.34
    p-tert-butyltoluene 16.5
    methyl 4-tert-butylbenzoate 79.88
    morpholine 481.89
    tert-butylamine 233.21
    n-dodecanol 28.41
    dimethoxymethane 505.28
    ethylene carbonate 79.19
    cyrene 181.04
    2-ethoxyethyl acetate 53.11
    2-ethylhexyl acetate 20.74
    1,2,4-trichlorobenzene 31.26
    4-methylpyridine 69.99
    dibutyl ether 26.24
    2,6-dimethyl-4-heptanol 37.34
    DEF 250.17
    dimethyl isosorbide 149.37
    tetrachloroethylene 102.52
    eugenol 96.16
    triacetin 58.38
    span 80 96.92
    1,4-butanediol 493.77
    1,1-dichloroethane 55.85
    2-methyl-1-pentanol 133.56
    methyl formate 522.89
    2-methyl-1-butanol 216.05
    n-decane 5.12
    butyronitrile 103.81
    3,7-dimethyl-1-octanol 54.6
    1-chlorooctane 18.78
    1-chlorotetradecane 7.69
    n-nonane 5.13
    undecane 3.94
    tert-butylcyclohexane 7.01
    cyclooctane 5.93
    cyclopentanol 233.35
    tetrahydropyran 153.48
    tert-amyl methyl ether 136.82
    2,5,8-trioxanonane 219.73
    1-hexene 20.4
    2-isopropoxyethanol 313.03
    2,2,2-trifluoroethanol 385.08
    methyl butyrate 84.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction