Methyl 2-hydroxy-6-methoxybenzoate

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    22833-69-8

    Molecular formula
    C9H10O4

    SMILES
    COC1=CC=CC(=C1C(=O)OC)O

  • Odor profile

    Sweet 63.65%
    Phenolic 49.8%
    Fruity 45.68%
    Green 43.66%
    Floral 42.73%
    Herbal 41.64%
    Spicy 36.68%
    Woody 35.1%
    Aromatic 32.6%
    Mint 32.41%

    Scent© AI

  • Properties

    XLogP3-AA
    1.9

    Molecular weight
    182.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    273°C

    Flash point est.
    121.74 ˚C

  • Synonyms

    • Methyl 2-hydroxy-6-methoxybenzoate
    • 22833-69-8
    • methyl 6-methoxysalicylate
    • Benzoic acid, 2-hydroxy-6-methoxy-, methyl ester
    • 2-HYDROXY-6-METHOXYBENZOIC ACID METHYL ESTER
    • MFCD06204264
    • Methyl 6-hydroxy-o-anisate
    • DTXSID30335771
    • o-Anisic acid, 6-hydroxy-, methyl ester
    • 2-Hydroxy-6-methoxy benzoic acid methyl ester
    • SCHEMBL1339134
    • CHEMBL2252248
    • DTXCID80286860
    • Methyl2-hydroxy-6-methoxybenzoate
    • ALBB-032197
    • AKOS006292478
    • DS-8897
    • FH69792
    • Methyl 2-hydroxy-6-methoxybenzoic acid
    • SY121391
    • DB-125114
    • CS-0042723
    • 2-hydroxy-6-methoxy-benzoic acid methyl ester
    • Y13599

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 151.73
    methanol 240.29
    isopropanol 89.38
    water 0.73
    ethyl acetate 89.41
    n-propanol 98.08
    acetone 227.18
    n-butanol 87.72
    acetonitrile 126.99
    DMF 903.53
    toluene 33.71
    isobutanol 65.28
    1,4-dioxane 252.8
    methyl acetate 126.68
    THF 437.76
    2-butanone 124.32
    n-pentanol 67.31
    sec-butanol 59.62
    n-hexane 3.4
    ethylene glycol 161.38
    NMP 330.37
    cyclohexane 7.33
    DMSO 807.45
    n-butyl acetate 41.46
    n-octanol 38.25
    chloroform 212.73
    n-propyl acetate 52.09
    acetic acid 89.61
    dichloromethane 265.97
    cyclohexanone 164.89
    propylene glycol 95.2
    isopropyl acetate 46.67
    DMAc 364.32
    2-ethoxyethanol 168.15
    isopentanol 61.86
    n-heptane 4.47
    ethyl formate 144.84
    1,2-dichloroethane 190.45
    n-hexanol 68.56
    2-methoxyethanol 432.01
    isobutyl acetate 32.64
    tetrachloromethane 33.46
    n-pentyl acetate 33.25
    transcutol 91.13
    n-heptanol 36.46
    ethylbenzene 25.62
    MIBK 62.02
    2-propoxyethanol 168.36
    tert-butanol 105.12
    MTBE 44.87
    2-butoxyethanol 78.42
    propionic acid 77.11
    o-xylene 28.9
    formic acid 96.29
    diethyl ether 56.36
    m-xylene 31.51
    p-xylene 33.47
    chlorobenzene 65.76
    dimethyl carbonate 100.07
    n-octane 2.65
    formamide 196.12
    cyclopentanone 268.78
    2-pentanone 105.54
    anisole 76.54
    cyclopentyl methyl ether 107.33
    gamma-butyrolactone 289.41
    1-methoxy-2-propanol 234.04
    pyridine 144.64
    3-pentanone 72.8
    furfural 290.14
    n-dodecane 3.42
    diethylene glycol 238.01
    diisopropyl ether 14.15
    tert-amyl alcohol 66.15
    acetylacetone 150.42
    n-hexadecane 4.01
    acetophenone 78.77
    methyl propionate 122.3
    isopentyl acetate 36.38
    trichloroethylene 289.62
    n-nonanol 34.23
    cyclohexanol 76.16
    benzyl alcohol 96.08
    2-ethylhexanol 36.78
    isooctanol 28.04
    dipropyl ether 30.19
    1,2-dichlorobenzene 70.93
    ethyl lactate 61.51
    propylene carbonate 147.11
    n-methylformamide 365.55
    2-pentanol 41.89
    n-pentane 3.33
    1-propoxy-2-propanol 82.37
    1-methoxy-2-propyl acetate 70.1
    2-(2-methoxypropoxy) propanol 61.66
    mesitylene 21.18
    ε-caprolactone 115.74
    p-cymene 19.74
    epichlorohydrin 347.49
    1,1,1-trichloroethane 111.07
    2-aminoethanol 153.58
    morpholine-4-carbaldehyde 328.22
    sulfolane 440.9
    2,2,4-trimethylpentane 2.91
    2-methyltetrahydrofuran 147.99
    n-hexyl acetate 48.57
    isooctane 2.82
    2-(2-butoxyethoxy)ethanol 78.05
    sec-butyl acetate 28.71
    tert-butyl acetate 53.52
    decalin 6.43
    glycerin 181.0
    diglyme 151.11
    acrylic acid 86.63
    isopropyl myristate 21.65
    n-butyric acid 92.37
    acetyl acetate 58.95
    di(2-ethylhexyl) phthalate 30.69
    ethyl propionate 54.79
    nitromethane 279.64
    1,2-diethoxyethane 37.78
    benzonitrile 89.97
    trioctyl phosphate 27.36
    1-bromopropane 67.93
    gamma-valerolactone 305.46
    n-decanol 26.8
    triethyl phosphate 35.15
    4-methyl-2-pentanol 28.98
    propionitrile 95.09
    vinylene carbonate 144.83
    1,1,2-trichlorotrifluoroethane 277.71
    DMS 55.59
    cumene 20.84
    2-octanol 24.26
    2-hexanone 63.01
    octyl acetate 30.71
    limonene 27.06
    1,2-dimethoxyethane 255.02
    ethyl orthosilicate 27.9
    tributyl phosphate 27.6
    diacetone alcohol 109.08
    N,N-dimethylaniline 57.21
    acrylonitrile 155.36
    aniline 68.26
    1,3-propanediol 188.31
    bromobenzene 62.3
    dibromomethane 152.85
    1,1,2,2-tetrachloroethane 235.56
    2-methyl-cyclohexyl acetate 39.84
    tetrabutyl urea 44.87
    diisobutyl methanol 23.24
    2-phenylethanol 80.3
    styrene 31.21
    dioctyl adipate 36.14
    dimethyl sulfate 194.68
    ethyl butyrate 41.33
    methyl lactate 112.82
    butyl lactate 39.1
    diethyl carbonate 34.52
    propanediol butyl ether 67.89
    triethyl orthoformate 30.29
    p-tert-butyltoluene 20.02
    methyl 4-tert-butylbenzoate 66.61
    morpholine 261.71
    tert-butylamine 46.16
    n-dodecanol 21.13
    dimethoxymethane 377.43
    ethylene carbonate 110.94
    cyrene 108.62
    2-ethoxyethyl acetate 45.56
    2-ethylhexyl acetate 28.29
    1,2,4-trichlorobenzene 75.47
    4-methylpyridine 130.19
    dibutyl ether 23.73
    2,6-dimethyl-4-heptanol 23.24
    DEF 154.41
    dimethyl isosorbide 114.57
    tetrachloroethylene 153.64
    eugenol 74.04
    triacetin 47.65
    span 80 53.61
    1,4-butanediol 89.97
    1,1-dichloroethane 114.11
    2-methyl-1-pentanol 46.71
    methyl formate 343.57
    2-methyl-1-butanol 53.59
    n-decane 4.72
    butyronitrile 101.04
    3,7-dimethyl-1-octanol 32.99
    1-chlorooctane 22.52
    1-chlorotetradecane 10.88
    n-nonane 4.22
    undecane 3.98
    tert-butylcyclohexane 5.71
    cyclooctane 3.26
    cyclopentanol 111.09
    tetrahydropyran 127.94
    tert-amyl methyl ether 38.55
    2,5,8-trioxanonane 109.67
    1-hexene 15.41
    2-isopropoxyethanol 86.58
    2,2,2-trifluoroethanol 63.75
    methyl butyrate 86.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Cassie absolute (blossom) 8023-82-3 Acacia farnesiana (L.) Willd., fam. Mimosaceae (Leguminosae) 0.3%