Methyl 2-hydroxy-2-methylbutanoate

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  • Identifiers

    CAS number
    32793-34-3

    Molecular formula
    C6H12O3

    SMILES
    CCC(C)(C(=O)OC)O

    Safety labels

  • Odor profile

    Fragrance
    Fruity 86.38%
    Caramellic 62.73%
    Buttery 62.45%
    Sweet 44.57%
    Nutty 44.19%
    Creamy 40.8%
    Milky 36.56%
    Ethereal 33.27%
    Dairy 31.26%
    Winey 29.16%

     

    Flavor
    Fruity 84.29%
    Sweet 54.05%
    Creamy 43.59%
    Tropical 35.37%
    Fruit 34.05%
    Berry 32.98%
    Buttery 32.54%
    Green 32.03%
    Bitter 31.69%
    Grape 29.31%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    8.08 (weak base)

    Molecular weight
    132.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    150°C

    Flash point

    • 54.28 ˚C est.

  • Synonyms

    • Methyl 2-hydroxy-2-methylbutanoate
    • 32793-34-3
    • RefChem:1089331
    • Butanoic acid, 2-hydroxy-2-methyl-, methyl ester
    • SCHEMBL1063211
    • Methylaethylglykolsauremethylester
    • FMXYCZVOMYLMKM-UHFFFAOYSA-N
    • AKOS011495921
    • Methyl 2-hydroxy-2-methylbutanoate #
    • 32793-34-3

  • Applications

    Methyl 2-hydroxy-2-methylbutanoate (CAS 32793-34-3) is used primarily as an intermediate and processing aid in chemical synthesis, and can serve as a versatile building block in industrial manufacturing. In perfumery and cosmetics, it is commonly evaluated as an odorant/fragrance ingredient and as a solvent or carrier in formulations. In household products, it may function as a fragrance component or processing solvent. In the polymers/plastics sector, it can act as a potential monomer or co-monomer for polyester synthesis, or as a plasticizer in specialty formulations. In coatings and inks, it is used as a solvent/processing aid to improve flow and compatibility. In pharmaceuticals, it may be considered as a chiral building block or intermediate for synthesis, subject to regulatory and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2106.04
    methanol 3490.97
    isopropanol 1394.99
    water 160.79
    ethyl acetate 698.7
    n-propanol 1546.13
    acetone 1076.33
    n-butanol 1059.98
    acetonitrile 1020.17
    DMF 1495.72
    toluene 135.88
    isobutanol 1027.87
    1,4-dioxane 1888.49
    methyl acetate 756.35
    THF 1313.91
    2-butanone 731.82
    n-pentanol 827.15
    sec-butanol 1185.72
    n-hexane 72.42
    ethylene glycol 902.15
    NMP 855.27
    cyclohexane 88.35
    DMSO 1446.85
    n-butyl acetate 289.56
    n-octanol 314.99
    chloroform 1206.94
    n-propyl acetate 388.06
    acetic acid 1930.89
    dichloromethane 1131.07
    cyclohexanone 747.17
    propylene glycol 725.49
    isopropyl acetate 385.94
    DMAc 816.96
    2-ethoxyethanol 1625.49
    isopentanol 758.07
    n-heptane 40.54
    ethyl formate 708.79
    1,2-dichloroethane 713.84
    n-hexanol 506.67
    2-methoxyethanol 2328.3
    isobutyl acetate 211.89
    tetrachloromethane 291.39
    n-pentyl acetate 254.34
    transcutol 1468.12
    n-heptanol 303.96
    ethylbenzene 128.34
    MIBK 393.91
    2-propoxyethanol 930.41
    tert-butanol 1757.03
    MTBE 901.66
    2-butoxyethanol 541.34
    propionic acid 978.09
    o-xylene 151.88
    formic acid 1777.61
    diethyl ether 830.64
    m-xylene 130.61
    p-xylene 184.89
    chlorobenzene 260.01
    dimethyl carbonate 216.08
    n-octane 25.53
    formamide 1640.48
    cyclopentanone 865.67
    2-pentanone 598.47
    anisole 377.73
    cyclopentyl methyl ether 577.93
    gamma-butyrolactone 1140.0
    1-methoxy-2-propanol 1209.69
    pyridine 552.22
    3-pentanone 412.26
    furfural 924.68
    n-dodecane 20.73
    diethylene glycol 922.87
    diisopropyl ether 225.99
    tert-amyl alcohol 1325.56
    acetylacetone 608.58
    n-hexadecane 22.55
    acetophenone 345.89
    methyl propionate 507.26
    isopentyl acetate 279.81
    trichloroethylene 1179.15
    n-nonanol 243.28
    cyclohexanol 704.65
    benzyl alcohol 402.49
    2-ethylhexanol 256.13
    isooctanol 246.38
    dipropyl ether 218.5
    1,2-dichlorobenzene 288.72
    ethyl lactate 260.47
    propylene carbonate 517.26
    n-methylformamide 1267.2
    2-pentanol 714.67
    n-pentane 81.39
    1-propoxy-2-propanol 496.1
    1-methoxy-2-propyl acetate 321.23
    2-(2-methoxypropoxy) propanol 367.23
    mesitylene 104.58
    ε-caprolactone 712.38
    p-cymene 96.21
    epichlorohydrin 1120.72
    1,1,1-trichloroethane 587.35
    2-aminoethanol 1368.86
    morpholine-4-carbaldehyde 1145.47
    sulfolane 1168.21
    2,2,4-trimethylpentane 72.66
    2-methyltetrahydrofuran 1045.96
    n-hexyl acetate 390.03
    isooctane 48.57
    2-(2-butoxyethoxy)ethanol 534.52
    sec-butyl acetate 247.25
    tert-butyl acetate 492.47
    decalin 54.12
    glycerin 974.61
    diglyme 920.84
    acrylic acid 827.32
    isopropyl myristate 133.76
    n-butyric acid 990.99
    acetyl acetate 358.45
    di(2-ethylhexyl) phthalate 134.5
    ethyl propionate 325.93
    nitromethane 2270.21
    1,2-diethoxyethane 423.13
    benzonitrile 381.03
    trioctyl phosphate 117.11
    1-bromopropane 383.23
    gamma-valerolactone 1253.06
    n-decanol 169.26
    triethyl phosphate 128.98
    4-methyl-2-pentanol 379.38
    propionitrile 623.6
    vinylene carbonate 518.75
    1,1,2-trichlorotrifluoroethane 965.05
    DMS 266.09
    cumene 118.88
    2-octanol 231.29
    2-hexanone 412.01
    octyl acetate 180.78
    limonene 152.04
    1,2-dimethoxyethane 1477.14
    ethyl orthosilicate 129.64
    tributyl phosphate 128.47
    diacetone alcohol 656.89
    N,N-dimethylaniline 270.28
    acrylonitrile 748.8
    aniline 325.82
    1,3-propanediol 1516.69
    bromobenzene 216.97
    dibromomethane 701.42
    1,1,2,2-tetrachloroethane 984.84
    2-methyl-cyclohexyl acetate 209.98
    tetrabutyl urea 156.0
    diisobutyl methanol 166.15
    2-phenylethanol 297.4
    styrene 147.07
    dioctyl adipate 177.61
    dimethyl sulfate 382.24
    ethyl butyrate 231.88
    methyl lactate 341.53
    butyl lactate 234.83
    diethyl carbonate 152.95
    propanediol butyl ether 501.25
    triethyl orthoformate 172.29
    p-tert-butyltoluene 99.81
    methyl 4-tert-butylbenzoate 306.55
    morpholine 1775.98
    tert-butylamine 994.52
    n-dodecanol 124.1
    dimethoxymethane 912.47
    ethylene carbonate 442.78
    cyrene 377.68
    2-ethoxyethyl acetate 332.89
    2-ethylhexyl acetate 200.59
    1,2,4-trichlorobenzene 359.52
    4-methylpyridine 479.38
    dibutyl ether 190.65
    2,6-dimethyl-4-heptanol 166.15
    DEF 676.83
    dimethyl isosorbide 475.46
    tetrachloroethylene 808.21
    eugenol 325.86
    triacetin 304.18
    span 80 303.9
    1,4-butanediol 796.33
    1,1-dichloroethane 660.79
    2-methyl-1-pentanol 618.47
    methyl formate 1004.38
    2-methyl-1-butanol 806.61
    n-decane 34.92
    butyronitrile 616.57
    3,7-dimethyl-1-octanol 245.05
    1-chlorooctane 139.02
    1-chlorotetradecane 52.85
    n-nonane 35.21
    undecane 25.32
    tert-butylcyclohexane 61.47
    cyclooctane 33.27
    cyclopentanol 818.19
    tetrahydropyran 1083.22
    tert-amyl methyl ether 642.79
    2,5,8-trioxanonane 590.05
    1-hexene 216.16
    2-isopropoxyethanol 883.43
    2,2,2-trifluoroethanol 711.8
    methyl butyrate 484.35

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction