Methoxyfenozide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    161050-58-4

    Molecular formula
    C22H28N2O3

    SMILES
    CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C(=CC=C2)OC)C)C

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Floral 35.7%
    Fruity 33.94%
    Musk 29.76%
    Citrus 29.14%
    Grapefruit 28.95%
    Odorless 28.61%
    Grape 28.48%
    Dry 28.28%
    Woody 25.73%
    Mint 25.24%

     

    Flavor
    Bitter 76.89%
    Odorless 32.01%
    Bland 27.36%
    Cedarleaf 19.38%
    Heather 19.22%
    Broom 19.14%
    Sweet-like 19.11%
    Parsley 18.98%
    Nitrile 18.8%
    Genet 18.7%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.6

    pKa est.
    6.28 (neutral)

    Molecular weight
    368.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    840°C

    Melting point expt.

    • 206.2 - 208 °C
    • MP: 204 - 20.6 °C /Technical/

    Flash point

    • 197.68 ˚C est.

    Solubility expt.

    • In DMSO 11, cyclohexanone 9.9, acetone 9 (all in g/100g at 20 °C)
    • In water, 3.3 mg/L at 20 °C

  • Synonyms

    • Methoxyfenozide
    • 161050-58-4
    • Intrepid
    • N'-tert-Butyl-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
    • Runner
    • Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
    • 3-Methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
    • RH-2485
    • N'-(tert-butyl)-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
    • N-tert-butyl-N'-(3-methoxy-o-toluoyl)-3,5-xylohydrazide
    • DTXSID3032628
    • 62A22651ZX
    • DTXCID1012628
    • CHEBI:38449
    • RH-112485
    • RefChem:157081
    • N-tert-butyl-N'-(3-methoxy-2-methylbenzoyl)-3,5-dimethylbenzohydrazide
    • 605-245-2
    • N'-(tert-Butyl )-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
    • MFCD03792750
    • 163442-56-6
    • CHEMBL55772
    • Methoxyfenozide 10 microg/mL in Acetonitrile
    • RG 102398; RH 112485; RH 2485
    • Methoxyphenozide
    • Intrepid (pesticide)
    • Methoxyfenozide [ISO:ANSI:BSI]
    • RH 2485
    • Prodigy
    • UNII-62A22651ZX
    • HSDB 7936
    • RG 102398
    • RH 112485
    • Methoxyfenozide (Standard)
    • METHOXYFENOZIDE [MI]
    • SCHEMBL27595
    • METHOXYFENOZIDE [ISO]
    • orb1306860
    • GLXC-07887
    • MSK20363
    • Tox21_301100
    • BDBM50128305
    • 3-Methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-tert-butylhydrazide
    • AKOS015895784
    • HY-117386R
    • NCGC00163951-01
    • NCGC00163951-02
    • NCGC00163951-03
    • NCGC00255000-01
    • DS-16494
    • DB-241062
    • HY-117386
    • CAS-161050-58-4
    • CS-0065614
    • NS00000434
    • C18525
    • C73059
    • 050M584
    • Methoxyfenozide, PESTANAL(R), analytical standard
    • Q15632812
    • N-tert-butyl-N''-(3-methoxy-o-toluoyl)-3,5-xylohydrazide
    • N''-tert-butyl-N''-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
    • N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methyl-benzohydrazide
    • N''-(tert-butyl)-N''-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
    • N-(3-methoxy-2-methylbenzoyl)-N'(3,5-dimethylbenzoyl)-N'-tert-butylhydrazine
    • N-(3-methoxy-2-methylbenzoyl)-N'-(3,5-dimethylbenzoyl)-N'-tert-butylhydrazine
    • Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethyl-benzoyl)-2-(1,1-dimethylethyl)hydrazide
    • Methoxyphenozide ; Prodigy 240SC; N'-(tert-butyl)-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
    • 161050-58-4

  • Applications

    Methoxyfenozide (CAS 161050-58-4) is an insect growth regulator used in agriculture to manage lepidopteran pests. It is commonly applied to protect fruit crops (such as apples, pears, grapes, and citrus) and vegetables, as well as cotton and ornamental or greenhouse crops, from caterpillar pests. Applications are typically foliar sprays and are often integrated into IPM programs in field or orchard settings. The product is formulated as emulsifiable concentrates (EC) or other formulations like SC/WDG, and use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 86.1
    methanol 85.12
    isopropanol 55.5
    water 0.12
    ethyl acetate 138.81
    n-propanol 77.26
    acetone 170.55
    n-butanol 72.69
    acetonitrile 70.3
    DMF 391.97
    toluene 84.88
    isobutanol 59.32
    1,4-dioxane 197.06
    methyl acetate 148.19
    THF 385.98
    2-butanone 166.62
    n-pentanol 58.79
    sec-butanol 61.06
    n-hexane 4.37
    ethylene glycol 11.41
    NMP 388.25
    cyclohexane 5.04
    DMSO 129.11
    n-butyl acetate 101.6
    n-octanol 22.79
    chloroform 459.24
    n-propyl acetate 85.37
    acetic acid 191.59
    dichloromethane 337.38
    cyclohexanone 238.26
    propylene glycol 22.35
    isopropyl acetate 109.42
    DMAc 528.07
    2-ethoxyethanol 117.5
    isopentanol 68.42
    n-heptane 2.26
    ethyl formate 84.65
    1,2-dichloroethane 249.77
    n-hexanol 66.75
    2-methoxyethanol 162.91
    isobutyl acetate 70.11
    tetrachloromethane 38.48
    n-pentyl acetate 65.37
    transcutol 205.17
    n-heptanol 34.05
    ethylbenzene 39.45
    MIBK 94.32
    2-propoxyethanol 165.27
    tert-butanol 65.95
    MTBE 96.82
    2-butoxyethanol 95.35
    propionic acid 83.25
    o-xylene 44.62
    formic acid 62.81
    diethyl ether 95.27
    m-xylene 47.45
    p-xylene 52.51
    chlorobenzene 134.59
    dimethyl carbonate 103.74
    n-octane 1.27
    formamide 95.22
    cyclopentanone 282.24
    2-pentanone 140.4
    anisole 87.24
    cyclopentyl methyl ether 135.83
    gamma-butyrolactone 282.37
    1-methoxy-2-propanol 129.62
    pyridine 185.28
    3-pentanone 124.35
    furfural 213.63
    n-dodecane 1.05
    diethylene glycol 100.51
    diisopropyl ether 26.32
    tert-amyl alcohol 71.96
    acetylacetone 172.66
    n-hexadecane 1.24
    acetophenone 99.31
    methyl propionate 140.38
    isopentyl acetate 106.52
    trichloroethylene 494.91
    n-nonanol 24.36
    cyclohexanol 69.0
    benzyl alcohol 76.54
    2-ethylhexanol 35.44
    isooctanol 29.02
    dipropyl ether 39.33
    1,2-dichlorobenzene 121.33
    ethyl lactate 48.36
    propylene carbonate 155.53
    n-methylformamide 134.15
    2-pentanol 48.5
    n-pentane 3.67
    1-propoxy-2-propanol 89.71
    1-methoxy-2-propyl acetate 134.6
    2-(2-methoxypropoxy) propanol 72.55
    mesitylene 21.99
    ε-caprolactone 208.68
    p-cymene 21.21
    epichlorohydrin 412.3
    1,1,1-trichloroethane 217.07
    2-aminoethanol 36.52
    morpholine-4-carbaldehyde 337.15
    sulfolane 278.25
    2,2,4-trimethylpentane 3.87
    2-methyltetrahydrofuran 213.11
    n-hexyl acetate 74.14
    isooctane 2.22
    2-(2-butoxyethoxy)ethanol 95.31
    sec-butyl acetate 73.96
    tert-butyl acetate 106.14
    decalin 5.08
    glycerin 36.7
    diglyme 194.66
    acrylic acid 86.6
    isopropyl myristate 25.43
    n-butyric acid 128.83
    acetyl acetate 115.47
    di(2-ethylhexyl) phthalate 35.13
    ethyl propionate 84.15
    nitromethane 285.27
    1,2-diethoxyethane 94.34
    benzonitrile 76.95
    trioctyl phosphate 22.36
    1-bromopropane 109.62
    gamma-valerolactone 374.75
    n-decanol 16.62
    triethyl phosphate 40.06
    4-methyl-2-pentanol 34.7
    propionitrile 70.36
    vinylene carbonate 149.91
    1,1,2-trichlorotrifluoroethane 240.43
    DMS 96.08
    cumene 25.62
    2-octanol 20.67
    2-hexanone 91.74
    octyl acetate 35.71
    limonene 28.27
    1,2-dimethoxyethane 191.11
    ethyl orthosilicate 38.66
    tributyl phosphate 29.67
    diacetone alcohol 112.32
    N,N-dimethylaniline 64.24
    acrylonitrile 91.37
    aniline 94.92
    1,3-propanediol 67.9
    bromobenzene 135.14
    dibromomethane 198.13
    1,1,2,2-tetrachloroethane 404.49
    2-methyl-cyclohexyl acetate 65.1
    tetrabutyl urea 42.58
    diisobutyl methanol 19.74
    2-phenylethanol 86.96
    styrene 47.3
    dioctyl adipate 41.97
    dimethyl sulfate 152.94
    ethyl butyrate 68.71
    methyl lactate 69.18
    butyl lactate 53.79
    diethyl carbonate 50.89
    propanediol butyl ether 54.15
    triethyl orthoformate 51.63
    p-tert-butyltoluene 20.52
    methyl 4-tert-butylbenzoate 78.29
    morpholine 238.11
    tert-butylamine 35.14
    n-dodecanol 11.34
    dimethoxymethane 202.5
    ethylene carbonate 128.35
    cyrene 95.42
    2-ethoxyethyl acetate 112.61
    2-ethylhexyl acetate 80.93
    1,2,4-trichlorobenzene 147.16
    4-methylpyridine 207.13
    dibutyl ether 27.42
    2,6-dimethyl-4-heptanol 19.74
    DEF 186.46
    dimethyl isosorbide 149.55
    tetrachloroethylene 228.22
    eugenol 75.42
    triacetin 75.72
    span 80 55.81
    1,4-butanediol 30.6
    1,1-dichloroethane 215.51
    2-methyl-1-pentanol 64.09
    methyl formate 118.3
    2-methyl-1-butanol 70.77
    n-decane 1.91
    butyronitrile 71.95
    3,7-dimethyl-1-octanol 26.63
    1-chlorooctane 15.55
    1-chlorotetradecane 5.57
    n-nonane 1.61
    undecane 1.36
    tert-butylcyclohexane 4.78
    cyclooctane 1.66
    cyclopentanol 79.57
    tetrahydropyran 163.66
    tert-amyl methyl ether 83.86
    2,5,8-trioxanonane 111.17
    1-hexene 23.82
    2-isopropoxyethanol 87.49
    2,2,2-trifluoroethanol 82.28
    methyl butyrate 109.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction