Methoxychlor

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  • Identifiers

    CAS number
    72-43-5

    Molecular formula
    C16H15Cl3O2

    SMILES
    COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)C(Cl)(Cl)Cl

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Floral 71.37%
    Sweet 49.68%
    Rose 41.66%
    Balsamic 36.33%
    Fruity 35.48%
    Powdery 34.01%
    Animal 27.67%
    Neroli 27.18%
    Lily 26.88%
    Honey 26.03%

     

    Flavor
    Bitter 40.67%
    Mild 25.24%
    Odorless 22.78%
    Bland 20.09%
    Cedarleaf 19.08%
    Heather 18.86%
    Broom 18.7%
    Creosote 18.69%
    Nitrile 18.68%
    Very strong 18.62%

     

    Odor impact est.
    Low

    Odor threshold

    • 4.7 mg/kg in water

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    7.06 (neutral)

    Molecular weight
    345.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 187 to 190 °F (NTP, 1992)
    • 87 °C
    • MP: 172 °F (77.78 °C)
    • MP: 89 °C (technical, 77 °C)
    • 89 °C
    • 171 °F

    Boiling point

    • Decomposes (NTP, 1992)
    • decomposes
    • Decomposes

    Flash point

    • 162.88 ˚C est.

    Solubility expt.

    • less than 1 mg/mL at 73 °F (NTP, 1992)
    • Soluble in alcohol
    • Moderately sol in alcohol and petroleum oils; readily sol in most aromatic solvents
    • Methylene dichloride: 60 g/100 g at 22 °C; dichlorobenzene: 40 g/100 g at 22 °C; cyclohexanone: 50 g/100 g at 22 °C; methylated naphthalenes: 30 g/100 g at 22 °C; carbon tetrachloride: 16 g/100 g at 22 °C; odorless kerosene: 2 g/100 g at 22 °C. /Data from table/
    • Readily soluble in aromatic, chlorinated, and ketonic solvents, and vegetable oils. In chloroform and xylene 440, methanol 50 (all in g/kg, 22 °C).
    • For more Solubility (Complete) data for METHOXYCHLOR (9 total), please visit the HSDB record page.
    • Solubility in water: none
    • 0.00001%

  • Synonyms

    • methoxychlor
    • 72-43-5
    • p,p'-Methoxychlor
    • Dimethoxy-DDT
    • DMDT
    • Methoxy-DDT
    • Methoxcide
    • Metox
    • Maralate
    • Marlate
    • Moxie
    • Higalmetox
    • Metoksychlor
    • Dianisyltrichlorethane
    • Mezox K
    • Dianisyl trichloroethane
    • Methoxychlor 2 ec
    • Methoxychlore
    • Dimethoxy-DT
    • Rcra waste number U247
    • Methoxo
    • 2,2-Bis(p-anisyl)-1,1,1-trichloroethane
    • Caswell No. 550
    • Metoksychlor [Polish]
    • NCI-C00497
    • Methoxychlor, technical
    • p,p'-DMDT
    • ENT 1,716
    • MeOCl
    • 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane
    • Double-M ec
    • 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane
    • Methoxychlor [BSI:ISO]
    • OMS 466
    • Methoxychlor [ISO]
    • Methoxychlore [ISO-French]
    • 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane
    • 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane
    • Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-
    • CCRIS 380
    • pMethoxychlor
    • HSDB 1173
    • Flo pro mcseed protectant
    • 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane
    • 2,2-Di-p-anisyl-1,1,1-trichloroethane
    • 1-Methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene
    • 4,4-(2,2,2-Trichloroethylidene)dianisole
    • Mesox K
    • NSC 8945
    • Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-
    • EINECS 200-779-9
    • Methoxychlor (Methoxy-DDT)
    • p,p'-Dimethoxydiphenyltrichloroethane
    • RIA79UD69L
    • p,p'-Dwumetoksydwufenylotrojchloroetan
    • 1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene)
    • Methoxychlor-d14)
    • Dimethoxydiphenyltrichloroethane
    • EPA Pesticide Chemical Code 034001
    • Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-
    • 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane
    • BRN 2057367
    • CHEBI:6842
    • 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis(4-methoxybenzene)
    • 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane
    • DTXSID9020827
    • Methoxychlor [95%]
    • NSC-8945
    • METHOXYCHLOR [MI]
    • MFCD00000803
    • p,p'-Dwumetoksydwufenylotrojchloroetan [Polish]
    • 2,2-Di(p-methoxyphenyl)-1,1,1-trichloroethane
    • 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane
    • METHOXYCHLOR [HSDB]
    • METHOXYCHLOR [IARC]
    • 1,1,1-Trichloro-2,2-bis-(p-methoxyphenyl)ethane
    • p,p'-(Dimethoxydiphenyl)trichloroethane
    • 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan
    • METHOXYCHLOR [MART.]
    • Di(p-methoxyphenyl)trichloromethyl methane
    • DTXCID30827
    • METHOXYCHLOR [WHO-DD]
    • 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German]
    • 1644449-82-0
    • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy-
    • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-
    • Methoxychlor-d6
    • 2,2-Bis(4-methoxyphenyl)-1,1,1-trichloroethane
    • Methoxychlor 10 microg/mL in Isooctane
    • NCGC00090760-08
    • Methoxychlor 10 microg/mL in Acetonitrile
    • 2,2-Di(p-anisyl)-1,1,1-trichloroethane
    • Methoxychlor 100 microg/mL in Cyclohexane
    • METHOXYCHLOR (IARC)
    • Methoxychlore (ISO-French)
    • METHOXYCHLOR (MART.)
    • METOKSYCHLOR (POLISH)
    • 2,2-Bis (p-methoxyphenol)-1,1,1-trichloroethane
    • Metoxicloro
    • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis [4-methoxy-
    • Maxie
    • DMDT;Dimethoxy-DDT; Marlate; Mesox K; Methoxcide; Methoxy-DDT
    • 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis[4-(methyloxy)benzene]
    • Methoxy DDT
    • SMR000568481
    • dianisyltrichloroethane
    • p,p'-Dwumetoksydwufenylotrojchloroetan (Polish)
    • Trichloroethane, Dianisyl
    • RCRA waste no. U247
    • UNII-RIA79UD69L
    • 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan (German)
    • DimethoxyDDT
    • 1-methoxy-4-(2,2,2-trichloro-1-(4-methoxyphenyl)ethyl)benzene
    • BENZENE, 1,1'-(2,2,2-TRICHLOROETHYLIDENE)BIS (4-METHOXY-
    • MethoxyDDT
    • Dimethox ydiphenyltrichloroethane
    • p,p'Methoxychlor
    • 1-(2H3)methoxy-4-(2,2,2-trichloro-1-(4-(2H3)methoxy(2,3,5,6-2H4)phenyl)ethyl)(2H4)benzene
    • 1-(2H3)methoxy-4-{2,2,2-trichloro-1-[4-(2H3)methoxy(2,3,5,6-2H4)phenyl]ethyl}(2H4)benzene
    • p, p'-Methoxychlor
    • p,p'-Dimethoxydiphenylftrichloroethane
    • 4,4'-Methoxychlor
    • p,p'-dimethoxydiphenyltrichl oroethane
    • Methoxychlor technical
    • Bis(p-anisyl)-1,1,1-trichloroethane
    • METOX PLYNNY
    • Metoxicloro (Spanish)
    • Spectrum_001949

  • Applications

    Methoxychlor (CAS 72-43-5) is an organochlorine insecticide used in agriculture to protect crops such as fruits, vegetables, and grains from pest insects. It has been employed for stored-product pest control to safeguard stored grains and other agricultural commodities. In nursery and greenhouse settings, it has been used for pest management on ornamental plants and potted crops. It also serves as an active ingredient in a number of commercial pesticide formulations. Due to persistence and environmental and health concerns, its use is subject to regulatory restrictions and has been phased out or restricted in many regions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 20.14
    methanol 9.22
    isopropanol 16.02
    water 0.0
    ethyl acetate 181.3
    n-propanol 24.24
    acetone 158.25
    n-butanol 26.34
    acetonitrile 56.66
    DMF 226.96
    toluene 107.81
    isobutanol 19.04
    1,4-dioxane 325.79
    methyl acetate 153.04
    THF 800.67
    2-butanone 169.48
    n-pentanol 29.94
    sec-butanol 27.06
    n-hexane 3.73
    ethylene glycol 3.22
    NMP 202.2
    cyclohexane 8.21
    DMSO 168.59
    n-butyl acetate 129.5
    n-octanol 19.21
    chloroform 791.98
    n-propyl acetate 114.08
    acetic acid 38.15
    dichloromethane 729.78
    cyclohexanone 236.42
    propylene glycol 8.78
    isopropyl acetate 106.25
    DMAc 327.54
    2-ethoxyethanol 104.54
    isopentanol 26.49
    n-heptane 6.02
    ethyl formate 87.5
    1,2-dichloroethane 325.36
    n-hexanol 36.48
    2-methoxyethanol 110.99
    isobutyl acetate 77.37
    tetrachloromethane 44.49
    n-pentyl acetate 81.51
    transcutol 246.26
    n-heptanol 20.24
    ethylbenzene 54.28
    MIBK 82.11
    2-propoxyethanol 132.08
    tert-butanol 30.77
    MTBE 92.48
    2-butoxyethanol 61.02
    propionic acid 29.91
    o-xylene 49.32
    formic acid 7.03
    diethyl ether 113.24
    m-xylene 56.81
    p-xylene 62.29
    chlorobenzene 152.28
    dimethyl carbonate 84.84
    n-octane 3.56
    formamide 21.72
    cyclopentanone 349.59
    2-pentanone 140.5
    anisole 173.41
    cyclopentyl methyl ether 209.12
    gamma-butyrolactone 330.81
    1-methoxy-2-propanol 95.35
    pyridine 265.77
    3-pentanone 120.36
    furfural 310.58
    n-dodecane 3.39
    diethylene glycol 67.79
    diisopropyl ether 31.99
    tert-amyl alcohol 37.1
    acetylacetone 240.24
    n-hexadecane 4.06
    acetophenone 137.68
    methyl propionate 147.78
    isopentyl acetate 115.13
    trichloroethylene 776.67
    n-nonanol 21.55
    cyclohexanol 46.44
    benzyl alcohol 92.94
    2-ethylhexanol 36.55
    isooctanol 20.92
    dipropyl ether 78.11
    1,2-dichlorobenzene 136.32
    ethyl lactate 50.44
    propylene carbonate 167.28
    n-methylformamide 55.0
    2-pentanol 23.2
    n-pentane 2.95
    1-propoxy-2-propanol 97.02
    1-methoxy-2-propyl acetate 183.38
    2-(2-methoxypropoxy) propanol 89.5
    mesitylene 29.45
    ε-caprolactone 213.94
    p-cymene 36.84
    epichlorohydrin 598.46
    1,1,1-trichloroethane 276.01
    2-aminoethanol 9.43
    morpholine-4-carbaldehyde 311.87
    sulfolane 280.75
    2,2,4-trimethylpentane 4.59
    2-methyltetrahydrofuran 325.4
    n-hexyl acetate 79.46
    isooctane 3.09
    2-(2-butoxyethoxy)ethanol 96.58
    sec-butyl acetate 85.25
    tert-butyl acetate 124.5
    decalin 8.11
    glycerin 16.56
    diglyme 246.85
    acrylic acid 28.52
    isopropyl myristate 41.62
    n-butyric acid 59.31
    acetyl acetate 125.35
    di(2-ethylhexyl) phthalate 41.26
    ethyl propionate 114.85
    nitromethane 166.11
    1,2-diethoxyethane 177.19
    benzonitrile 110.07
    trioctyl phosphate 26.51
    1-bromopropane 137.46
    gamma-valerolactone 440.44
    n-decanol 17.45
    triethyl phosphate 67.61
    4-methyl-2-pentanol 18.45
    propionitrile 54.4
    vinylene carbonate 151.19
    1,1,2-trichlorotrifluoroethane 247.05
    DMS 111.64
    cumene 33.5
    2-octanol 18.08
    2-hexanone 104.03
    octyl acetate 47.92
    limonene 51.15
    1,2-dimethoxyethane 284.91
    ethyl orthosilicate 64.9
    tributyl phosphate 37.59
    diacetone alcohol 101.09
    N,N-dimethylaniline 95.41
    acrylonitrile 71.25
    aniline 96.56
    1,3-propanediol 23.09
    bromobenzene 193.21
    dibromomethane 369.47
    1,1,2,2-tetrachloroethane 513.86
    2-methyl-cyclohexyl acetate 92.49
    tetrabutyl urea 53.37
    diisobutyl methanol 25.89
    2-phenylethanol 90.39
    styrene 73.0
    dioctyl adipate 69.78
    dimethyl sulfate 134.41
    ethyl butyrate 118.02
    methyl lactate 53.96
    butyl lactate 54.25
    diethyl carbonate 86.87
    propanediol butyl ether 43.05
    triethyl orthoformate 96.55
    p-tert-butyltoluene 35.67
    methyl 4-tert-butylbenzoate 93.5
    morpholine 333.8
    tert-butylamine 18.89
    n-dodecanol 14.56
    dimethoxymethane 245.16
    ethylene carbonate 125.4
    cyrene 117.84
    2-ethoxyethyl acetate 144.97
    2-ethylhexyl acetate 98.55
    1,2,4-trichlorobenzene 165.03
    4-methylpyridine 245.04
    dibutyl ether 53.92
    2,6-dimethyl-4-heptanol 25.89
    DEF 165.41
    dimethyl isosorbide 213.15
    tetrachloroethylene 252.74
    eugenol 91.0
    triacetin 108.47
    span 80 61.46
    1,4-butanediol 11.35
    1,1-dichloroethane 253.09
    2-methyl-1-pentanol 35.08
    methyl formate 65.41
    2-methyl-1-butanol 27.61
    n-decane 5.45
    butyronitrile 65.47
    3,7-dimethyl-1-octanol 26.82
    1-chlorooctane 25.94
    1-chlorotetradecane 13.35
    n-nonane 4.6
    undecane 4.2
    tert-butylcyclohexane 7.61
    cyclooctane 2.97
    cyclopentanol 55.68
    tetrahydropyran 266.56
    tert-amyl methyl ether 87.18
    2,5,8-trioxanonane 178.02
    1-hexene 23.77
    2-isopropoxyethanol 80.83
    2,2,2-trifluoroethanol 21.54
    methyl butyrate 133.87

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction