Methandrostenolone

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  • Identifiers

    CAS number
    72-63-9

    Molecular formula
    C20H28O2

    SMILES
    C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CCC4=CC(=O)C=C[C@]34C

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Woody 66.62%
    Fruity 62.73%
    Cedar 35.77%
    Amber 32.04%
    Berry 31.68%
    Dry 30.0%
    Spicy 29.35%
    Sweet 26.95%
    Fresh 26.92%
    Musk 26.85%

     

    Flavor
    Bitter 43.93%
    Minty 27.28%
    Ripe apricot 22.21%
    Spicy 22.15%
    Cedarleaf 21.79%
    Red fruit 21.64%
    Fresh 21.53%
    Basil 21.35%
    Soil 21.33%
    Lovage 21.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.6

    pKa est.
    7.4 (neutral)

    Molecular weight
    300.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    357°C

    Melting point expt.

    • 163-164 °C
    • 163.5 °C

    Flash point

    • 192.72 ˚C est.

    Solubility expt.

    • SOL IN ALC, CHLOROFORM, GLACIAL ACETIC ACID; SLIGHTLY SOL IN ETHER; INSOL IN WATER

  • Synonyms

    • METHANDROSTENOLONE
    • Metandienone
    • Methandienone
    • 72-63-9
    • Dianabol
    • Nerobol
    • Metanabol
    • Metandienonum
    • Methandrolone
    • Metandienon
    • Metandrostenolon
    • Metandrostenolone
    • Anabolin
    • Andoredan
    • Dianabole
    • Encephan
    • Metastenol
    • Nerobolettes
    • Perbolin
    • Protobolin
    • Stenolon
    • Stenolone
    • Abirol
    • Danabol
    • Geabol
    • Naposim
    • Crein
    • Dehydromethyltestosterone
    • Anabolicum Medivet
    • Methylandrostenolone
    • Metandienona
    • Methandienonum
    • 1-Dehydromethyltestosterone
    • Compound 17309
    • Methandrostenolonum
    • Ciba 17309-ba
    • NSC-42722
    • 1,2-Dehydro-17-methyltestosterone
    • A1-Dehydromethyltesterone
    • 17beta-Hydroxy-17-methylandrosta-1,4-dien-3-one
    • Ciba 17309 BA
    • delta'-17-Methyltestosterone
    • Metandienonum [Latin]
    • Testosterone, 1-dehydro-17-methyl-
    • 1-Dehydro-17alpha-methyltestosterone
    • 17alpha-Methyl-1-dehydrotestosterone
    • 1-Dehydro-17-alpha-methyltestosterone
    • 17-alpha-Methyl-1-dehydrotestosterone
    • TMV 17
    • COZ1R7EOCC
    • UNII-COZ1R7EOCC
    • HSDB 3360
    • delta(1)-17alpha-Methyltestosterone
    • delta-1,17-alpha-Methyltestosterone
    • EINECS 200-787-2
    • NSC 42722
    • Metandienone [INN]
    • DTXSID2023276
    • delta(sup 1)-17-alpha-Methyltestosterone
    • 17-beta-Hydroxy-17-alpha-methylandrostra-1,4-dien-3-one
    • Androsta-1,4-dien-3-one, 17-beta-hydroxy-17-alpha-methyl-
    • Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17beta)-
    • 17-beta-hydroxy-17-methyl-androsta-1,4-dien-3-one
    • Sterolon
    • 17alpha-Methyl-17beta-hydroxyandrosta-1,4-dien-3-one
    • Androsta-1,4-dien-3-one, 17beta-hydroxy-17-methyl-
    • 17-alpha-Methyl-17-beta-hydroxy-1,4-androstadien-3-one
    • DTXCID203276
    • 1-Dehydro-17-methyltestosterone
    • NSC42722
    • Metandienone (INN)
    • (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
    • MA
    • Metandienonum (Latin)
    • NCGC00159415-02
    • NCGC00159415-04
    • 1-Dehydro-17-.alpha.-methyltestosterone
    • Androsta-1,4-diene-3-one, 17-hydroxy-17-methyl-, (17beta)-
    • Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17-beta)-
    • METHANDIENONE (MART.)
    • METHANDIENONE [MART.]
    • (17beta)-17-hydroxy-17-methylandrosta-1,4-dien-3-one
    • .delta.'-17-Methyltestosterone
    • Metandienona [Spanish]
    • Methandrostenolone [USP]
    • Metandrostenolone [DCIT]
    • Metandienonum [INN-Latin]
    • 1-Dehydro-17.alpha.-methyltestosterone
    • 17.alpha.-Methyl-1-dehydrotestosterone
    • CAS-72-63-9
    • MA (VAN)
    • Metandienona [INN-Spanish]
    • .DELTA.1-17.alpha.-Methyltestosterone
    • Androsta-1, 17.beta.-hydroxy-17-methyl-
    • Androsta-1, 17.beta.-hydroxy-17.alpha.-methyl-
    • Androsta-1, 17-hydroxy-17-methyl-, (17.beta.)-
    • 17-.beta.-hydroxy-17-methyl-androsta-1,4-dien-3-one
    • Methandrostenolone (1.0 mg/mL in 1,2-Dimethoxyethane)
    • Methandrostenolone (Metandienone)
    • 17-.beta.-Hydroxy-17-.alpha.-methylandrostra-1,4-dien-3-one
    • Androsta-1,4-diene-3-one, 17-hydroxy-17-methyl-, (17.beta.)-
    • 17-Hydroxy-17-methylandrosta-1,4-dien-3-one
    • Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17b)-
    • DIANABOL (TN)
    • METANDIENONE [WHO-DD]
    • SCHEMBL140928
    • Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17.alpha.)-
    • METHANDROSTENOLONE [MI]
    • CHEBI:6810
    • CHEMBL1418176
    • METHANDROSTENOLONE [HSDB]
    • METHANDROSTENOLONE [VANDF]
    • MSK2297
    • 1-Dehydro-17-methyl-Testosterone
    • Methandienone, 1mg/ml in Methanol
    • BCP10774
    • NSC51180
    • Tox21_111647
    • 1, 2-Dehydro-17-methyltestosterone
    • BBL029917
    • LMST02020013
    • NSC-51180
    • s4796
    • STK801870
    • AKOS005267170
    • Tox21_111647_1
    • CCG-267474
    • DB13586

  • Applications

    Methandrostenolone (CAS 72-63-9) is a synthetic anabolic steroid used as an active pharmaceutical ingredient in endocrinology in markets where it is permitted, with anabolic effects in selected hormone replacement contexts. In the pharmaceutical industry it is commonly treated as a building block or intermediate for the synthesis of related steroid compounds. In research and development, it serves as a reference compound and starting point for optimizing steroid synthesis processes, and it appears in academic and contract research laboratory settings under local regulatory controls.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 51.69
    methanol 52.72
    isopropanol 46.93
    water 0.37
    ethyl acetate 85.04
    n-propanol 58.58
    acetone 103.71
    n-butanol 54.9
    acetonitrile 40.82
    DMF 213.39
    toluene 186.32
    isobutanol 33.24
    1,4-dioxane 219.06
    methyl acetate 53.52
    THF 326.25
    2-butanone 69.19
    n-pentanol 14.78
    sec-butanol 15.84
    n-hexane 1.59
    ethylene glycol 9.74
    NMP 48.35
    cyclohexane 9.53
    DMSO 72.44
    n-butyl acetate 48.93
    n-octanol 8.56
    chloroform 269.37
    n-propyl acetate 34.33
    acetic acid 35.46
    dichloromethane 144.59
    cyclohexanone 115.14
    propylene glycol 11.72
    isopropyl acetate 81.09
    DMAc 106.43
    2-ethoxyethanol 44.97
    isopentanol 40.44
    n-heptane 1.61
    ethyl formate 29.21
    1,2-dichloroethane 85.34
    n-hexanol 30.56
    2-methoxyethanol 122.77
    isobutyl acetate 32.1
    tetrachloromethane 30.67
    n-pentyl acetate 31.53
    transcutol 230.84
    n-heptanol 17.28
    ethylbenzene 36.41
    MIBK 63.92
    2-propoxyethanol 114.73
    tert-butanol 46.65
    MTBE 31.2
    2-butoxyethanol 58.19
    propionic acid 28.96
    o-xylene 56.91
    formic acid 19.77
    diethyl ether 66.8
    m-xylene 86.16
    p-xylene 42.15
    chlorobenzene 91.96
    dimethyl carbonate 66.13
    n-octane 0.74
    formamide 47.65
    cyclopentanone 132.06
    2-pentanone 75.23
    anisole 86.7
    cyclopentyl methyl ether 79.82
    gamma-butyrolactone 111.67
    1-methoxy-2-propanol 117.37
    pyridine 186.97
    3-pentanone 62.83
    furfural 109.68
    n-dodecane 0.6
    diethylene glycol 82.34
    diisopropyl ether 20.24
    tert-amyl alcohol 14.99
    acetylacetone 133.45
    n-hexadecane 0.76
    acetophenone 64.76
    methyl propionate 73.2
    isopentyl acetate 56.12
    trichloroethylene 194.8
    n-nonanol 10.51
    cyclohexanol 36.34
    benzyl alcohol 50.05
    2-ethylhexanol 16.26
    isooctanol 15.33
    dipropyl ether 28.99
    1,2-dichlorobenzene 78.28
    ethyl lactate 25.38
    propylene carbonate 59.41
    n-methylformamide 73.48
    2-pentanol 22.71
    n-pentane 3.01
    1-propoxy-2-propanol 70.75
    1-methoxy-2-propyl acetate 108.76
    2-(2-methoxypropoxy) propanol 53.94
    mesitylene 42.9
    ε-caprolactone 78.09
    p-cymene 18.05
    epichlorohydrin 145.07
    1,1,1-trichloroethane 85.08
    2-aminoethanol 26.6
    morpholine-4-carbaldehyde 136.93
    sulfolane 85.47
    2,2,4-trimethylpentane 1.29
    2-methyltetrahydrofuran 67.14
    n-hexyl acetate 32.3
    isooctane 1.94
    2-(2-butoxyethoxy)ethanol 73.75
    sec-butyl acetate 34.03
    tert-butyl acetate 80.92
    decalin 3.45
    glycerin 29.7
    diglyme 161.06
    acrylic acid 28.71
    isopropyl myristate 16.92
    n-butyric acid 61.01
    acetyl acetate 77.83
    di(2-ethylhexyl) phthalate 23.58
    ethyl propionate 44.31
    nitromethane 93.37
    1,2-diethoxyethane 63.75
    benzonitrile 65.45
    trioctyl phosphate 14.36
    1-bromopropane 43.13
    gamma-valerolactone 195.73
    n-decanol 7.6
    triethyl phosphate 26.43
    4-methyl-2-pentanol 21.89
    propionitrile 62.22
    vinylene carbonate 78.69
    1,1,2-trichlorotrifluoroethane 86.97
    DMS 60.48
    cumene 19.42
    2-octanol 8.27
    2-hexanone 28.35
    octyl acetate 18.03
    limonene 16.41
    1,2-dimethoxyethane 110.02
    ethyl orthosilicate 25.67
    tributyl phosphate 16.42
    diacetone alcohol 67.08
    N,N-dimethylaniline 48.36
    acrylonitrile 81.48
    aniline 120.94
    1,3-propanediol 56.59
    bromobenzene 98.33
    dibromomethane 89.77
    1,1,2,2-tetrachloroethane 148.92
    2-methyl-cyclohexyl acetate 38.14
    tetrabutyl urea 22.76
    diisobutyl methanol 15.47
    2-phenylethanol 66.4
    styrene 45.16
    dioctyl adipate 27.31
    dimethyl sulfate 75.32
    ethyl butyrate 40.4
    methyl lactate 44.0
    butyl lactate 33.61
    diethyl carbonate 33.03
    propanediol butyl ether 36.86
    triethyl orthoformate 37.33
    p-tert-butyltoluene 19.47
    methyl 4-tert-butylbenzoate 57.39
    morpholine 192.02
    tert-butylamine 24.57
    n-dodecanol 5.52
    dimethoxymethane 228.83
    ethylene carbonate 69.48
    cyrene 49.1
    2-ethoxyethyl acetate 71.01
    2-ethylhexyl acetate 39.25
    1,2,4-trichlorobenzene 85.12
    4-methylpyridine 152.26
    dibutyl ether 12.35
    2,6-dimethyl-4-heptanol 15.47
    DEF 59.24
    dimethyl isosorbide 99.5
    tetrachloroethylene 98.25
    eugenol 62.39
    triacetin 56.96
    span 80 40.34
    1,4-butanediol 11.58
    1,1-dichloroethane 83.52
    2-methyl-1-pentanol 13.7
    methyl formate 45.53
    2-methyl-1-butanol 23.67
    n-decane 1.14
    butyronitrile 47.03
    3,7-dimethyl-1-octanol 12.78
    1-chlorooctane 5.62
    1-chlorotetradecane 2.49
    n-nonane 0.9
    undecane 0.79
    tert-butylcyclohexane 2.6
    cyclooctane 3.12
    cyclopentanol 30.97
    tetrahydropyran 144.55
    tert-amyl methyl ether 18.27
    2,5,8-trioxanonane 101.01
    1-hexene 6.64
    2-isopropoxyethanol 32.66
    2,2,2-trifluoroethanol 24.51
    methyl butyrate 42.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction