Menthone 1,2-glycerol ketal, (+/-)-

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  • Identifiers

    CAS number
    63187-91-7

    Molecular formula
    C13H24O3

    SMILES
    CC1CCC(C2(C1)OCC(O2)CO)C(C)C

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Mint 51.51%
    Odorless 43.47%
    Cooling 36.33%
    Herbal 28.61%
    Fresh 27.08%
    Animal 21.02%
    Lactonic 18.78%
    Natural 18.36%
    Woody 17.49%
    Clean 17.19%

     

    Flavor
    Green 37.64%
    Minty 33.12%
    Sweet 30.63%
    Fatty 27.51%
    Herbal 26.85%
    Earthy 26.62%
    Metallic 26.28%
    Vegetable 24.34%
    Caramel 24.04%
    Tropical 23.55%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    7.36 (neutral)

    Molecular weight
    228.33 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point

    • 322.00 to 323.00 °C. @ 760.00 mm Hg

    Flash point

    • 122.21 ˚C est.

    Solubility expt.

    • soluble in water, olive oil <15% and almond oil 1% w/w
    • soluble in water, olive oil <15% and almond oil 1% w/w

  • Synonyms

    • 63187-91-7
    • Menthone 1,2-glycerol ketal
    • 6-Isopropyl-9-methyl-1,4-dioxaspiro[4.5]decane-2-methanol
    • Frescolat MGA
    • Menthone glycerin acetal
    • 1,4-Dioxaspiro[4.5]decane-2-methanol, 9-methyl-6-(1-methylethyl)-
    • menthone glyceryl ketal
    • 7QQ1EE6RCP
    • Menthone 1,2-glyceryl ketal
    • 6-Isopropyl-9-methyl-1,4-dioxaspiro(4.5)decane-2-methanol
    • (9-methyl-6-propan-2-yl-1,4-dioxaspiro[4.5]decan-3-yl)methanol
    • Menthone 1,2-glycerol ketal, (+/-)-
    • FEMA NO. 3808
    • (6-isopropyl-9-methyl-1,4-dioxaspiro[4.5]decan-2-yl)methanol
    • EC 408-200-3
    • 1,4-Dioxaspiro(4.5)decane-2-methanol, 9-methyl-6-(1-methylethyl)-
    • FRESCOLAT, TYPE MGA RACEMIC
    • DL-MENTHONE 1,2-GLYCEROL KETAL
    • 9-Methyl-6-(1-methylethyl)-1,4-dioxaspiro(4.5)decane-2-methanol
    • 2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxaspiro(4.5)decane
    • DL-MENTHONE (+/-)-1,2-GLYCEROL KETAL
    • [9-methyl-6-(propan-2-yl)-1,4-dioxaspiro[4.5]decan-2-yl]methanol
    • 2-hydroxymethyl-9-methyl-6-(1-methylethyl)-1,4-dioxaspiro[4.5]decane
    • UNII-7QQ1EE6RCP
    • 9-Methyl-6-(1-methylethyl)-1,4-dioxaspiro[4.5]decane-2-methanol
    • Menthoneglycerinacetal
    • starbld0009751
    • SCHEMBL169625
    • GTPL2465
    • FEMA 3807
    • FEMA 3808
    • DTXSID20866983
    • CHEBI:169866
    • ZBJCYZPANVLBRK-UHFFFAOYSA-N
    • (9-methyl-6-propan-2-yl-1,4-dioxaspiro[4.5]decan-2-yl)methanol
    • (+/-)-menthone 1,2-glycerol ketal
    • AKOS015908506
    • AC-9867
    • MENTHONE GLYCERIN ACETAL [INCI]
    • CS-0454364
    • NS00003186
    • E79266
    • D,L-MENTHONE 1,2-GLYCEROL KETAL [FHFI]
    • Q27077744
    • 6-Isopropyl-9-methyl-1,4-dioxaspiro(4,5)decane-2-methanol
    • 1,4-Dioxaspiro4.5decane-2-methanol, 9-methyl-6-(1-methylethyl)-
    • 2-Hydroxymethyl-6-isopropyl-9-methyl-1,4-dioxaspiro[4.5]decane
    • 9-Methyl-6-(1-methylethyl)-1,4-dioxaspiro[4.5]decane-2-methanol, 9CI
    • 408-200-3
    • 613-178-5

  • Applications

    Menthone 1,2-glycerol ketal, (+/-)- (CAS 63187-91-7) is primarily used as an aroma ingredient and a fixative in perfumery, helping to extend and stabilize fragrance notes in scents and cosmetics. It is also applied in household products such as cleaners and air fresheners to impart a minty, fresh aroma. In fragrance chemistry, it serves as an intermediate or building block for menthone-derived aroma components. Overall, its use is subject to local regulations and formulation limits, and it may be evaluated for additional fragrance applications in research and development.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 740.78
    methanol 861.46
    isopropanol 809.31
    water 2.74
    ethyl acetate 636.68
    n-propanol 772.73
    acetone 879.17
    n-butanol 710.68
    acetonitrile 599.46
    DMF 689.46
    toluene 454.58
    isobutanol 668.7
    1,4-dioxane 1002.91
    methyl acetate 550.61
    THF 1793.37
    2-butanone 690.4
    n-pentanol 414.78
    sec-butanol 667.48
    n-hexane 46.85
    ethylene glycol 162.01
    NMP 741.14
    cyclohexane 151.36
    DMSO 911.37
    n-butyl acetate 570.03
    n-octanol 281.03
    chloroform 3124.15
    n-propyl acetate 429.27
    acetic acid 861.02
    dichloromethane 2256.63
    cyclohexanone 1294.66
    propylene glycol 279.13
    isopropyl acetate 489.68
    DMAc 484.56
    2-ethoxyethanol 450.62
    isopentanol 589.93
    n-heptane 38.15
    ethyl formate 577.93
    1,2-dichloroethane 1069.91
    n-hexanol 483.47
    2-methoxyethanol 731.23
    isobutyl acetate 347.93
    tetrachloromethane 473.88
    n-pentyl acetate 421.94
    transcutol 998.89
    n-heptanol 273.24
    ethylbenzene 219.28
    MIBK 416.11
    2-propoxyethanol 600.8
    tert-butanol 721.6
    MTBE 525.18
    2-butoxyethanol 393.54
    propionic acid 635.1
    o-xylene 274.4
    formic acid 243.95
    diethyl ether 515.64
    m-xylene 317.11
    p-xylene 304.63
    chlorobenzene 751.57
    dimethyl carbonate 234.22
    n-octane 20.65
    formamide 270.18
    cyclopentanone 1404.34
    2-pentanone 652.29
    anisole 355.67
    cyclopentyl methyl ether 707.88
    gamma-butyrolactone 1532.1
    1-methoxy-2-propanol 603.64
    pyridine 966.08
    3-pentanone 423.09
    furfural 1202.7
    n-dodecane 20.48
    diethylene glycol 423.71
    diisopropyl ether 187.88
    tert-amyl alcohol 511.75
    acetylacetone 644.58
    n-hexadecane 24.23
    acetophenone 392.03
    methyl propionate 450.39
    isopentyl acetate 529.82
    trichloroethylene 2097.61
    n-nonanol 224.1
    cyclohexanol 782.16
    benzyl alcohol 416.69
    2-ethylhexanol 286.43
    isooctanol 227.26
    dipropyl ether 239.14
    1,2-dichlorobenzene 624.56
    ethyl lactate 243.72
    propylene carbonate 966.51
    n-methylformamide 482.09
    2-pentanol 501.57
    n-pentane 63.72
    1-propoxy-2-propanol 441.54
    1-methoxy-2-propyl acetate 467.98
    2-(2-methoxypropoxy) propanol 302.15
    mesitylene 209.03
    ε-caprolactone 1042.72
    p-cymene 166.85
    epichlorohydrin 1356.2
    1,1,1-trichloroethane 1132.26
    2-aminoethanol 342.02
    morpholine-4-carbaldehyde 734.44
    sulfolane 1462.54
    2,2,4-trimethylpentane 51.41
    2-methyltetrahydrofuran 1132.28
    n-hexyl acetate 569.79
    isooctane 40.56
    2-(2-butoxyethoxy)ethanol 408.28
    sec-butyl acetate 318.56
    tert-butyl acetate 463.94
    decalin 65.34
    glycerin 340.37
    diglyme 677.6
    acrylic acid 561.21
    isopropyl myristate 193.84
    n-butyric acid 979.04
    acetyl acetate 504.74
    di(2-ethylhexyl) phthalate 207.37
    ethyl propionate 331.36
    nitromethane 926.53
    1,2-diethoxyethane 344.26
    benzonitrile 636.07
    trioctyl phosphate 173.22
    1-bromopropane 685.25
    gamma-valerolactone 1354.39
    n-decanol 156.74
    triethyl phosphate 178.03
    4-methyl-2-pentanol 273.33
    propionitrile 571.39
    vinylene carbonate 874.01
    1,1,2-trichlorotrifluoroethane 923.83
    DMS 390.42
    cumene 159.51
    2-octanol 205.0
    2-hexanone 406.54
    octyl acetate 258.13
    limonene 228.33
    1,2-dimethoxyethane 671.02
    ethyl orthosilicate 171.59
    tributyl phosphate 202.34
    diacetone alcohol 438.91
    N,N-dimethylaniline 223.7
    acrylonitrile 610.19
    aniline 546.04
    1,3-propanediol 520.1
    bromobenzene 812.31
    dibromomethane 1560.45
    1,1,2,2-tetrachloroethane 1642.73
    2-methyl-cyclohexyl acetate 321.98
    tetrabutyl urea 210.74
    diisobutyl methanol 165.78
    2-phenylethanol 403.28
    styrene 274.97
    dioctyl adipate 270.85
    dimethyl sulfate 369.21
    ethyl butyrate 352.66
    methyl lactate 294.15
    butyl lactate 341.2
    diethyl carbonate 251.55
    propanediol butyl ether 408.48
    triethyl orthoformate 246.44
    p-tert-butyltoluene 157.0
    methyl 4-tert-butylbenzoate 365.02
    morpholine 1055.68
    tert-butylamine 441.03
    n-dodecanol 116.97
    dimethoxymethane 506.83
    ethylene carbonate 794.48
    cyrene 331.91
    2-ethoxyethyl acetate 445.28
    2-ethylhexyl acetate 403.91
    1,2,4-trichlorobenzene 750.78
    4-methylpyridine 905.13
    dibutyl ether 234.91
    2,6-dimethyl-4-heptanol 165.78
    DEF 500.33
    dimethyl isosorbide 515.48
    tetrachloroethylene 1107.01
    eugenol 319.99
    triacetin 459.26
    span 80 331.78
    1,4-butanediol 236.33
    1,1-dichloroethane 1262.36
    2-methyl-1-pentanol 371.06
    methyl formate 454.15
    2-methyl-1-butanol 557.08
    n-decane 37.66
    butyronitrile 709.68
    3,7-dimethyl-1-octanol 257.31
    1-chlorooctane 202.57
    1-chlorotetradecane 71.17
    n-nonane 35.7
    undecane 26.5
    tert-butylcyclohexane 57.54
    cyclooctane 49.89
    cyclopentanol 877.87
    tetrahydropyran 1197.74
    tert-amyl methyl ether 335.0
    2,5,8-trioxanonane 416.65
    1-hexene 197.47
    2-isopropoxyethanol 336.89
    2,2,2-trifluoroethanol 353.24
    methyl butyrate 469.78

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction