(-)-Menthol

  • Identifiers

    CAS mumber
    2216-51-5

    Molecular formula
    C10H20O

    SMILES
    C[C@@H]1CC[C@H]([C@@H](C1)O)C(C)C

    Retention indicies (RI)

    • DB5: 1187.0
    • Carbowax: 1633.5

  • Properties

    XLogP3-AA
    3.0 Well soluble in DEP, BB, MMB

    Molecular weight
    156.26 g/mol

    Melting points

    • 100 °F (NTP, 1992)
    • 43 °C
    • 41-43 °C
    • 43 °C

    Boiling points

    • 421 °F at 760 mmHg (NTP, 1992)
    • 212 °C
    • 212 °C

    Flash points

    • 196 °F (NTP, 1992)

    Solubilities

    • less than 1 mg/mL at 70 °F (NTP, 1992)
    • 490 mg/L (at 25 °C)
    • Very sol in alcohol, chloroform, ether, petroleum ether; freely sol in glacial acetic acid, liquid petrolatum
    • VERY SOLUBLE IN ACETONE, BENZENE
    • In water, 456 mg/l @ 25 °C
    • 0.49 mg/mL at 25 °C
    • very soluble in alcohol and volatile oils; slightly soluble in water

  • Synonyms

    • l-Menthol
    • (-)-menthol
    • 2216-51-5
    • Levomenthol
    • l-(-)-Menthol
    • Menthomenthol
    • (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
    • Menthacamphor
    • Peppermint camphor
    • (1r,2s,5r)-(-)-menthol
    • U.S.P. Menthol
    • Levomentholum
    • Racementhol
    • Hexahydrothymol
    • (-)-Menthyl alcohol
    • Menthol racemic
    • (1R)-(-)-Menthol
    • d,l-Menthol
    • (-)-(1R,3R,4S)-Menthol
    • (R)-(-)-Menthol
    • 89-78-1
    • D-(-)-Menthol
    • Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-
    • p-Menthan-3-ol
    • (-)-trans-p-Menthan-cis-ol
    • rac-Menthol
    • (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol
    • 1-Menthol
    • (L)-MENTHOL
    • Menthol(-)
    • levomentol
    • Menthol natural
    • Menthol, (1R,3R,4S)-(-)-
    • (1R,3R,4S)-(-)-MENTHOL
    • Menthol, dl-
    • NCI-C50000
    • Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-rel-
    • 1R-Menthol
    • NSC 62788
    • Racementol
    • Racemic menthol
    • Water-soluble menthol
    • (1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol
    • (1R,2S,5R)-Menthol
    • 5-Methyl-2-(1-methylethyl)cyclohexanol
    • MFCD00062979
    • (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanol
    • BZ1R15MTK7
    • (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanol
    • (+/-)-Menthol
    • (1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
    • CHEMBL470670
    • YS08XHA860
    • DTXSID1020805
    • DTXSID1022180
    • CHEBI:15409
    • NSC2603
    • Headache crystals
    • NSC-2603
    • (1R,2S,5R)-2-isopropyl-5-methylcyclohexan-1-ol
    • FEMA No. 2665
    • NSC-62788
    • Menthol (VAN)
    • Racementholum
    • Thymomenthol
    • Menthol, cis-1,3,trans-1,4-
    • l-Menthol (natural)
    • NSC 2603
    • (+-)-Menthol
    • I-menthol
    • Menthol racemique
    • Levomenthol; (-)-Menthol
    • Levomenthol [INN:BAN]
    • Racementhol [INN:BAN]
    • Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1.alpha.,2.beta.,5.alpha.)]-
    • Menthol natural, brazilian
    • Menthol, l-
    • Racementol [INN-Spanish]
    • rel-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
    • Levomentholum [INN-Latin]
    • Menthol racemique [French]
    • Racementholum [INN-Latin]
    • DTXCID802180
    • Tra-kill tracheal mite killer
    • (1alpha,2beta,5alpha)-5-methyl-2(1-methylethyl)cyclohexanol
    • DTXCID101305276
    • MEGGEZONE
    • CAS-89-78-1
    • CCRIS 375
    • CAS-2216-51-5
    • l-Menthol (TN)
    • CCRIS 3728
    • CCRIS 4666
    • HSDB 5662
    • SR-05000001936
    • (-)-p-Menthan-3-ol
    • EINECS 201-939-0
    • EINECS 218-690-9
    • EINECS 239-388-3
    • UNII-BZ1R15MTK7
    • (1R,2S,5R)-rel-2-Isopropyl-5-methylcyclohexanol
    • BRN 1902288
    • BRN 3194263
    • UNII-YS08XHA860
    • (+-)-(1R*,3R*,4S*)-Menthol
    • AI3-52408
    • Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1.alpha.,2.beta.,5.alpha.)-
    • Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R-(1alpha,2beta,5alpha))-
    • CYCLOHEXANOL, 5-METHYL-2-(1-METHYLETHYL)-, (1R-(1.ALPHA.,2.BETA.,5.ALPHA.))-
    • L-Menthol natural
    • 1 -menthol
    • NCGC00159382-02
    • 98167-53-4
    • L-MENTHOLUM
    • l-Menthol (JP18)
    • Spectrum_000305
    • DL-Menthol (Standard)
    • LEVOMENTHOL [II]
    • MENTHOL [MI]
    • 5-Methyl-2-(1-methylethyl)cyclohexanol, (1alpha,2beta,5alpha)-
    • L-MENTHOL [JAN]
    • Menthol, (+/-)-
    • Spectrum2_000855
    • Spectrum3_001561
    • Spectrum5_001060
    • LEVOMENTHOL [INN]
    • RACEMENTHOL [INN]
    • M0545
1 3

Botanical

Name CAS Botanical Proportion
Mentha gentilis var. lanata Mentha gentilis (L.) var. lanata (Rydb.) Fujita et Fujita, fam. Lamiaceae 23.0%
Pennyroyal 2 8013-99-8 Mentha pulegium L. (C.R. variety), fam. Lamiaceae (Labiatae) 0.01%
Pennyroyal 3 8013-99-8 Mentha pulegium L., fam. Lamiaceae (Labiatae) 0.05%
Peppermint 4 8006-90-4 Mentha piperita L., fam. Lamiaceae (Labiatae) 29.0%
Peppermint (France) 4 8006-90-4 Mentha piperita L. cultivar Mitcham, fam. Lamiaceae (Labiatae) 36.79%
Peppermint (France) 1 8006-90-4 Mentha piperita L. cultivar Mitcham, fam. Lamiaceae (Labiatae) 36.79%
Peppermint (France) 2 8006-90-4 Mentha piperita L. cultivar Hongroise, fam. Lamiaceae (Labiatae) 20.54%
Peppermint (France) 3 8006-90-4 Mentha officinalis Sole forma Pallescens Camus, fam. Lamiaceae (Labiatae) 32.6%
Peppermint (USA) 2 8006-90-4 Mentha piperita L. cultivar Mitcham, fam. Lamiaceae (Labiatae) 40.0%
Peppermint (USA) 6 8006-90-4 Mentha piperita L., fam. Lamiaceae (Labiatae) 29.0%
Eromenthe (USA) 2 Mentha spicata L., var. eromenthe, fam. Lamiaceae (Labiatae) 0.08%