m-TOLUIDINE

Overview IFRA Request a quote

  • Identifiers

    CAS number
    108-44-1

    Molecular formula
    C7H9N

    SMILES
    CC1=CC(=CC=C1)N

    Safety labels

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Floral 54.71%
    Animal 47.93%
    Woody 46.83%
    Sweet 40.68%
    Phenolic 38.46%
    Leathery 32.06%
    Dry 27.73%
    Oily 26.63%
    Musty 26.51%
    Green 26.42%

     

    Flavor
    Phenolic 38.21%
    Plastic 34.33%
    Medicinal 31.38%
    Sweet 27.03%
    Woody 26.82%
    Guaiacol 22.57%
    Naphthyl 22.3%
    Phenol 22.14%
    Flat 20.83%
    Penetrating 20.67%

     

    Odor impact est.
    Low

    Odor threshold

    • Odor Threshold Low: 0.46 [mmHg]. Odor Threshold High: 5.9 [mmHg]. Odor threshold values from American Industrial Hygiene Association

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    5.78 (weak acid)

    Molecular weight
    107.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Melting point expt.

    • -22.7 °F (USCG, 1999)
    • -31.3 °C
    • -30 °C
    • -23 °F

    Boiling point

    • 398.1 °F at 760 mmHg (USCG, 1999)
    • 203.3 °C
    • 203 °C
    • 398.1 °F
    • 397 °F

    Flash point

    • 86.41 ˚C est.
    • 186 °F (USCG, 1999)
    • 187 °F
    • 187 °F (86 °C) (Closed cup)
    • 85 °C c.c.

    Solubility expt.

    • 2 % (NIOSH, 2024)
    • Very soluble in acetone, benzene, diethyl ether, ethanol
    • Soluble in alcohol, ether, dilute acids
    • In water, 1.50X10+4 mg/L at 20 °C
    • Solubility in water, g/100ml at 25 °C: 0.1 (poor)
    • 2%

  • Synonyms

    • m-Toluidine
    • 3-Methylaniline
    • 108-44-1
    • 3-Toluidine
    • 3-AMINOTOLUENE
    • Benzenamine, 3-methyl-
    • m-Methylaniline
    • m-Tolylamine
    • m-Toluidin
    • 3-Methylbenzenamine
    • m-Aminotoluene
    • 3-Aminophenylmethane
    • Aniline, 3-methyl-
    • m-Methylbenzenamine
    • 1-Amino-3-methylbenzene
    • 3-Aminotoluen
    • 3-Amino-1-methylbenzene
    • meta-toluidine
    • m-Toluidyna [Polish]
    • 3-methylphenylamine
    • m-Toluidyna
    • NSC 15349
    • CCRIS 4325
    • HSDB 2043
    • EINECS 203-583-1
    • 3-methyl-benzamine
    • MFCD00007808
    • UNII-006FKQ96T3
    • BRN 0635944
    • DTXSID1026792
    • AI3-19859
    • NSC-15349
    • M-TOLUIDINE [MI]
    • (M-METHYLPHENYL)AMINE
    • 3-AMINOTOLUENE [HSDB]
    • DTXCID506792
    • EC 203-583-1
    • 006FKQ96T3
    • 4-12-00-01813 (Beilstein Handbook Reference)
    • m-Toluidine, 99%
    • m-Toluidyna (Polish)
    • m-Toluidin [Czech]
    • 3-Aminotoluen [Czech]
    • 3-methyl aniline
    • CAS-108-44-1
    • 1-Aminophenylmethane
    • metatoluidine
    • mAminotoluene
    • mMethylaniline
    • mToluidine
    • mToluidyna
    • mTolylamine
    • mToluidin
    • 3methylaniline
    • 3Aminotoluene
    • m-Aminotoluol
    • 3Aminotoluen
    • 3-methylanilin
    • 3Toluidine
    • m-tolyl-amine
    • 3-Aminotoluol
    • mMethylbenzenamine
    • meta-methylaniline
    • 3-methyl-aniline
    • 3Methylbenzenamine
    • phenmedipham TP3
    • Aniline, 3methyl
    • 3-Methylbenzolamin
    • 3Aminophenylmethane
    • 3-(methyl)aniline
    • 3-Aminophenylmethan
    • 1Amino3methylbenzene
    • 3Amino1methylbenzene
    • 3-methyl-phenylamine
    • m-Toluidine (ACGIH)
    • 3-Amino-1-methylbenzol
    • 3-Methylanilin (German)
    • 3-METHYLBENZENEAMINE
    • WLN: ZR C1
    • 3-Methylbenzolamin (German)
    • SCHEMBL11789
    • m-Toluidine, liquid or solid
    • 3-Aminophenylmethan (German)
    • Benzenamine, 3-methyl-(9CI)
    • CHEMBL3182179
    • m-Toluidine, analytical standard
    • BCP15285
    • NSC15349
    • Tox21_201265
    • Tox21_300568
    • STK387127
    • AKOS000119100
    • FT02112
    • PS-9299
    • NCGC00091601-02
    • NCGC00091601-03
    • NCGC00254415-01
    • NCGC00258817-01
    • m-Toluidine 100 microg/mL in Cyclohexane
    • NS00008859
    • T0298
    • EN300-18342
    • m-Toluidine, liquid or solid [UN1708] [Poison]
    • Q1880736
    • Z57127904
    • F2190-0419

  • Applications

    m-TOLUIDINE (CAS 108-44-1) is primarily used as an industrial chemical intermediate. In the dye and pigment sector, it serves as a building block for aromatic amine precursors and azo dye systems. It is also employed in coatings and ink formulations as a dye/pigment precursor, contributing to color development in paints and printing. In the polymers field, it functions as a starting material for specialty intermediates and polymer synthesis routes. Additionally, it is used in research and development for conductive polymer applications, where toluidine derivatives participate in the preparation of polyaniline-type materials used in electronics.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2994.14
    methanol 3107.92
    isopropanol 1460.92
    water 29.14
    ethyl acetate 1808.34
    n-propanol 1784.29
    acetone 3615.78
    n-butanol 1387.42
    acetonitrile 2943.75
    DMF 1140.91
    toluene 191.39
    isobutanol 818.78
    1,4-dioxane 2287.38
    methyl acetate 1544.89
    THF 3556.43
    2-butanone 1588.32
    n-pentanol 757.5
    sec-butanol 849.0
    n-hexane 117.93
    ethylene glycol 310.52
    NMP 794.02
    cyclohexane 85.7
    DMSO 1665.98
    n-butyl acetate 943.25
    n-octanol 206.46
    chloroform 624.49
    n-propyl acetate 595.35
    acetic acid 2063.72
    dichloromethane 554.56
    cyclohexanone 1155.59
    propylene glycol 341.72
    isopropyl acetate 653.73
    DMAc 543.45
    2-ethoxyethanol 842.84
    isopentanol 659.71
    n-heptane 120.51
    ethyl formate 1032.49
    1,2-dichloroethane 423.95
    n-hexanol 1055.7
    2-methoxyethanol 1702.51
    isobutyl acetate 278.36
    tetrachloromethane 155.62
    n-pentyl acetate 250.72
    transcutol 1014.08
    n-heptanol 284.28
    ethylbenzene 38.38
    MIBK 424.73
    2-propoxyethanol 1334.05
    tert-butanol 1112.08
    MTBE 829.74
    2-butoxyethanol 445.36
    propionic acid 1205.55
    o-xylene 69.88
    formic acid 949.75
    diethyl ether 2014.52
    m-xylene 114.08
    p-xylene 59.21
    chlorobenzene 215.08
    dimethyl carbonate 310.17
    n-octane 29.13
    formamide 1215.59
    cyclopentanone 1792.17
    2-pentanone 1355.39
    anisole 178.88
    cyclopentyl methyl ether 1035.02
    gamma-butyrolactone 2027.71
    1-methoxy-2-propanol 922.71
    pyridine 686.77
    3-pentanone 783.34
    furfural 807.31
    n-dodecane 18.49
    diethylene glycol 711.74
    diisopropyl ether 280.83
    tert-amyl alcohol 557.3
    acetylacetone 885.22
    n-hexadecane 19.98
    acetophenone 129.96
    methyl propionate 1001.4
    isopentyl acetate 487.8
    trichloroethylene 579.59
    n-nonanol 171.22
    cyclohexanol 523.12
    benzyl alcohol 154.21
    2-ethylhexanol 335.25
    isooctanol 175.22
    dipropyl ether 744.27
    1,2-dichlorobenzene 118.65
    ethyl lactate 151.07
    propylene carbonate 668.65
    n-methylformamide 1450.54
    2-pentanol 697.92
    n-pentane 138.68
    1-propoxy-2-propanol 777.17
    1-methoxy-2-propyl acetate 530.38
    2-(2-methoxypropoxy) propanol 184.13
    mesitylene 61.12
    ε-caprolactone 786.88
    p-cymene 56.58
    epichlorohydrin 1238.07
    1,1,1-trichloroethane 478.3
    2-aminoethanol 677.58
    morpholine-4-carbaldehyde 823.8
    sulfolane 962.98
    2,2,4-trimethylpentane 34.84
    2-methyltetrahydrofuran 1836.5
    n-hexyl acetate 288.27
    isooctane 35.88
    2-(2-butoxyethoxy)ethanol 331.37
    sec-butyl acetate 257.99
    tert-butyl acetate 478.0
    decalin 22.68
    glycerin 356.07
    diglyme 628.12
    acrylic acid 766.04
    isopropyl myristate 92.5
    n-butyric acid 1521.39
    acetyl acetate 647.45
    di(2-ethylhexyl) phthalate 76.08
    ethyl propionate 395.97
    nitromethane 3272.57
    1,2-diethoxyethane 623.2
    benzonitrile 261.06
    trioctyl phosphate 68.89
    1-bromopropane 397.39
    gamma-valerolactone 1562.86
    n-decanol 127.44
    triethyl phosphate 99.44
    4-methyl-2-pentanol 249.48
    propionitrile 1239.92
    vinylene carbonate 517.55
    1,1,2-trichlorotrifluoroethane 449.57
    DMS 171.27
    cumene 32.79
    2-octanol 147.93
    2-hexanone 592.65
    octyl acetate 135.02
    limonene 117.56
    1,2-dimethoxyethane 1105.08
    ethyl orthosilicate 103.82
    tributyl phosphate 86.14
    diacetone alcohol 442.48
    N,N-dimethylaniline 79.41
    acrylonitrile 1004.46
    aniline 325.79
    1,3-propanediol 999.2
    bromobenzene 161.55
    dibromomethane 417.31
    1,1,2,2-tetrachloroethane 365.0
    2-methyl-cyclohexyl acetate 173.36
    tetrabutyl urea 95.56
    diisobutyl methanol 153.15
    2-phenylethanol 236.71
    styrene 58.34
    dioctyl adipate 104.45
    dimethyl sulfate 294.02
    ethyl butyrate 462.93
    methyl lactate 276.5
    butyl lactate 158.34
    diethyl carbonate 212.87
    propanediol butyl ether 222.27
    triethyl orthoformate 242.47
    p-tert-butyltoluene 60.47
    methyl 4-tert-butylbenzoate 123.4
    morpholine 2219.28
    tert-butylamine 608.2
    n-dodecanol 94.83
    dimethoxymethane 1144.0
    ethylene carbonate 524.62
    cyrene 148.82
    2-ethoxyethyl acetate 324.5
    2-ethylhexyl acetate 340.06
    1,2,4-trichlorobenzene 136.0
    4-methylpyridine 579.53
    dibutyl ether 284.96
    2,6-dimethyl-4-heptanol 153.15
    DEF 751.37
    dimethyl isosorbide 301.72
    tetrachloroethylene 265.12
    eugenol 132.04
    triacetin 163.15
    span 80 192.11
    1,4-butanediol 301.16
    1,1-dichloroethane 632.72
    2-methyl-1-pentanol 356.76
    methyl formate 1035.07
    2-methyl-1-butanol 602.07
    n-decane 33.57
    butyronitrile 1351.72
    3,7-dimethyl-1-octanol 169.48
    1-chlorooctane 108.65
    1-chlorotetradecane 38.81
    n-nonane 35.94
    undecane 23.95
    tert-butylcyclohexane 30.16
    cyclooctane 26.58
    cyclopentanol 812.33
    tetrahydropyran 1979.99
    tert-amyl methyl ether 414.67
    2,5,8-trioxanonane 344.59
    1-hexene 327.29
    2-isopropoxyethanol 438.31
    2,2,2-trifluoroethanol 486.22
    methyl butyrate 507.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction