Leprolomin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    68984-67-8

    Molecular formula
    C20H22O8

    SMILES
    CC1=C(C(=C(C=C1OC)OC2=C(C(=C(C(=C2O)C)OC)C(=O)C)O)C(=O)C)O

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 54.8%
    Spicy 47.01%
    Woody 43.71%
    Sweet 43.33%
    Balsamic 37.74%
    Smoky 37.19%
    Vanilla 36.36%
    Burnt 34.04%
    Dry 31.3%
    Powdery 30.99%

     

    Flavor
    Bitter 52.76%
    Odorless 27.66%
    Bland 26.14%
    Eugenol 22.11%
    Parsley 22.09%
    Mild 21.63%
    Sweet-like 20.63%
    Ham 20.56%
    Soybean 20.19%
    Thymol 20.13%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    8.3 (weak base)

    Molecular weight
    390.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1125°C

    Flash point

    • 227.52 ˚C est.

  • Synonyms

    • Leprolomin
    • 68984-67-8
    • DTXSID80219032
    • Ethanone, 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)-
    • RefChem:152826
    • DTXCID00141523
    • NSC646011
    • 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]ethanone
    • 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one
    • 1-[6-(3-Acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]ethan-1-one
    • orb1696552
    • CHEMBL1990200
    • AKOS040752482
    • NSC-646011
    • NCI60_015824
    • 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methyl-phenoxy)-2-hydroxy-4-methoxy-3-methyl-phenyl]ethanone
    • 68984-67-8

  • Applications

    Publicly available, reliable data on the specific uses of Leprolomin (CAS 68984-67-8) are very limited; based on general considerations for chemicals of this type, potential applications are reviewed at a high level to include as an intermediate in organic synthesis, as a solvent or processing aid in polymer and plastics manufacturing, as a stabilizer or additive in coatings, inks, and surface treatments, as a component in cleaning formulations or personal care products, and possibly as a chelating or stabilizing additive depending on its structure and safety profile; use details and regulatory acceptance depend on local rules and the supplier's safety data sheets and regulatory guidance.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.4
    methanol 2.51
    isopropanol 2.54
    water 0.0
    ethyl acetate 15.44
    n-propanol 3.27
    acetone 16.67
    n-butanol 3.37
    acetonitrile 6.59
    DMF 43.45
    toluene 1.98
    isobutanol 2.64
    1,4-dioxane 17.42
    methyl acetate 14.81
    THF 69.89
    2-butanone 19.94
    n-pentanol 3.09
    sec-butanol 3.67
    n-hexane 0.54
    ethylene glycol 1.0
    NMP 71.11
    cyclohexane 0.43
    DMSO 109.1
    n-butyl acetate 10.97
    n-octanol 1.69
    chloroform 28.53
    n-propyl acetate 8.14
    acetic acid 9.15
    dichloromethane 27.05
    cyclohexanone 26.23
    propylene glycol 1.4
    isopropyl acetate 9.72
    DMAc 74.35
    2-ethoxyethanol 9.09
    isopentanol 3.43
    n-heptane 0.36
    ethyl formate 8.03
    1,2-dichloroethane 22.85
    n-hexanol 4.28
    2-methoxyethanol 15.37
    isobutyl acetate 4.23
    tetrachloromethane 3.43
    n-pentyl acetate 5.61
    transcutol 10.51
    n-heptanol 2.26
    ethylbenzene 1.94
    MIBK 9.57
    2-propoxyethanol 16.02
    tert-butanol 4.74
    MTBE 6.58
    2-butoxyethanol 7.27
    propionic acid 6.0
    o-xylene 1.98
    formic acid 3.79
    diethyl ether 8.39
    m-xylene 1.57
    p-xylene 2.17
    chlorobenzene 4.83
    dimethyl carbonate 13.63
    n-octane 0.17
    formamide 8.0
    cyclopentanone 50.37
    2-pentanone 16.59
    anisole 6.47
    cyclopentyl methyl ether 16.2
    gamma-butyrolactone 54.1
    1-methoxy-2-propanol 13.42
    pyridine 13.27
    3-pentanone 16.6
    furfural 29.09
    n-dodecane 0.15
    diethylene glycol 10.33
    diisopropyl ether 2.47
    tert-amyl alcohol 5.7
    acetylacetone 23.13
    n-hexadecane 0.18
    acetophenone 8.34
    methyl propionate 18.28
    isopentyl acetate 9.55
    trichloroethylene 38.09
    n-nonanol 1.92
    cyclohexanol 4.38
    benzyl alcohol 4.01
    2-ethylhexanol 3.34
    isooctanol 2.0
    dipropyl ether 6.05
    1,2-dichlorobenzene 6.68
    ethyl lactate 5.86
    propylene carbonate 18.91
    n-methylformamide 14.05
    2-pentanol 2.7
    n-pentane 0.37
    1-propoxy-2-propanol 10.5
    1-methoxy-2-propyl acetate 16.08
    2-(2-methoxypropoxy) propanol 10.32
    mesitylene 1.13
    ε-caprolactone 21.15
    p-cymene 1.85
    epichlorohydrin 64.93
    1,1,1-trichloroethane 16.87
    2-aminoethanol 2.04
    morpholine-4-carbaldehyde 37.28
    sulfolane 110.77
    2,2,4-trimethylpentane 0.37
    2-methyltetrahydrofuran 26.04
    n-hexyl acetate 6.64
    isooctane 0.2
    2-(2-butoxyethoxy)ethanol 7.68
    sec-butyl acetate 5.94
    tert-butyl acetate 11.67
    decalin 0.54
    glycerin 4.56
    diglyme 20.45
    acrylic acid 6.31
    isopropyl myristate 2.85
    n-butyric acid 8.14
    acetyl acetate 10.62
    di(2-ethylhexyl) phthalate 4.12
    ethyl propionate 12.45
    nitromethane 37.25
    1,2-diethoxyethane 6.35
    benzonitrile 4.56
    trioctyl phosphate 3.29
    1-bromopropane 9.98
    gamma-valerolactone 47.06
    n-decanol 1.41
    triethyl phosphate 9.3
    4-methyl-2-pentanol 2.05
    propionitrile 7.12
    vinylene carbonate 14.15
    1,1,2-trichlorotrifluoroethane 36.44
    DMS 10.87
    cumene 1.57
    2-octanol 1.5
    2-hexanone 11.0
    octyl acetate 3.77
    limonene 2.91
    1,2-dimethoxyethane 26.17
    ethyl orthosilicate 7.66
    tributyl phosphate 4.35
    diacetone alcohol 14.24
    N,N-dimethylaniline 5.35
    acrylonitrile 10.07
    aniline 3.78
    1,3-propanediol 4.07
    bromobenzene 4.89
    dibromomethane 16.23
    1,1,2,2-tetrachloroethane 35.12
    2-methyl-cyclohexyl acetate 8.57
    tetrabutyl urea 7.3
    diisobutyl methanol 2.16
    2-phenylethanol 5.65
    styrene 1.83
    dioctyl adipate 5.55
    dimethyl sulfate 41.23
    ethyl butyrate 9.8
    methyl lactate 10.9
    butyl lactate 4.99
    diethyl carbonate 7.74
    propanediol butyl ether 3.61
    triethyl orthoformate 8.23
    p-tert-butyltoluene 1.74
    methyl 4-tert-butylbenzoate 10.05
    morpholine 22.75
    tert-butylamine 2.18
    n-dodecanol 1.06
    dimethoxymethane 28.59
    ethylene carbonate 12.13
    cyrene 15.87
    2-ethoxyethyl acetate 8.92
    2-ethylhexyl acetate 8.24
    1,2,4-trichlorobenzene 8.36
    4-methylpyridine 11.05
    dibutyl ether 2.89
    2,6-dimethyl-4-heptanol 2.16
    DEF 25.55
    dimethyl isosorbide 25.02
    tetrachloroethylene 19.27
    eugenol 8.09
    triacetin 7.94
    span 80 5.62
    1,4-butanediol 1.59
    1,1-dichloroethane 13.05
    2-methyl-1-pentanol 3.58
    methyl formate 12.66
    2-methyl-1-butanol 3.8
    n-decane 0.27
    butyronitrile 6.6
    3,7-dimethyl-1-octanol 2.02
    1-chlorooctane 1.63
    1-chlorotetradecane 0.69
    n-nonane 0.23
    undecane 0.19
    tert-butylcyclohexane 0.43
    cyclooctane 0.25
    cyclopentanol 6.65
    tetrahydropyran 14.08
    tert-amyl methyl ether 8.14
    2,5,8-trioxanonane 15.19
    1-hexene 2.03
    2-isopropoxyethanol 6.19
    2,2,2-trifluoroethanol 7.43
    methyl butyrate 13.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction