Leonoside B

Overview IFRA Request a quote

  • Identifiers

    CAS number
    140147-67-7

    Molecular formula
    C36H48O19

    SMILES
    CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)/C=C/C3=CC(=C(C=C3)O)OC)CO)OCCC4=CC(=C(C=C4)OC)O)O)OC5C(C(C(CO5)O)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 69.73%
    Vanilla 37.17%
    Sweet 31.23%
    Milky 25.14%
    Savory 22.47%
    Creamy 20.72%
    Spicy 19.08%
    Dairy 17.72%
    Balsamic 17.56%
    Cooling 15.88%

     

    Flavor
    Bitter 69.5%
    Odorless 35.86%
    Bland 34.76%
    Sweet-like 29.0%
    Very mild 21.32%
    Cedarleaf 20.52%
    Fatty 20.26%
    Parsley 20.03%
    Eugenol 19.58%
    Cauliflower 19.54%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.4

    pKa est.
    5.92 (weak acid)

    Molecular weight
    784.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    5912°C

    Flash point

    • 202.51 ˚C est.

  • Synonyms

    • Leonoside B
    • [4-[4,5-dihydroxy-6-methyl-3-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]oxy-5-hydroxy-6-[2-(3-hydroxy-4-methoxyphenyl)ethoxy]-2-(hydroxymethyl)oxan-3-yl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
    • beta-(3-Hydroxy, 4-methoxyphenyl)-ethyl-O-alpha-L-arabinopyranosyl-(1-2)-alpha-L-rhamnopyranosyl-(1-3)-4-O-feruloyl-beta-D-glycopyranoside
    • (4-(4,5-dihydroxy-6-methyl-3-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl)oxy-5-hydroxy-6-(2-(3-hydroxy-4-methoxyphenyl)ethoxy)-2-(hydroxymethyl)oxan-3-yl) (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
    • RefChem:152765
    • beta--D-Glucopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl O-alpha-L-arabinopyranosyl-(1-2)-O-6-deoxy-alpha-L-mannopyranosyl-(1-3)-, 4-(3-(4-hydroxy-3-methoxyphenyl)-2-propenoate)
    • 140147-67-7
    • 135010-56-9
    • CHEBI:169177
    • 4-((4,5-dihydroxy-6-methyl-3-((3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-(3-hydroxy-4-methoxyphenethoxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
    • beta-D-Glucopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl O-alpha-L-arabinopyranosyl-(1-2)-O-6-deoxy-alpha-L-mannopyranosyl-(1-3)-, 4-(3-(4-hydroxy-3-methoxyphenyl)-2-propenoate)
    • 140147-67-7

  • Applications

    Leonoside B, CAS 140147-67-7, is a natural glycoside that is primarily considered as a chemical intermediate and a basis for glycoside derivatives. Potential applications under evaluation include cosmetics/personal care as a functional ingredient, perfumery/fragrance as a scent-contributing component, pharmaceutical research as a scaffold for derivative synthesis, and agricultural/biotech contexts as a source of natural glycosides or for potential lead compounds. Real-world use depends on regulatory constraints and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.66
    methanol 12.8
    isopropanol 1.16
    water 0.31
    ethyl acetate 1.46
    n-propanol 2.33
    acetone 3.51
    n-butanol 1.53
    acetonitrile 1.03
    DMF 27.02
    toluene 0.42
    isobutanol 0.8
    1,4-dioxane 8.63
    methyl acetate 2.23
    THF 13.61
    2-butanone 2.7
    n-pentanol 0.81
    sec-butanol 1.1
    n-hexane 0.02
    ethylene glycol 7.3
    NMP 28.57
    cyclohexane 0.04
    DMSO 54.18
    n-butyl acetate 0.3
    n-octanol 0.78
    chloroform 1.19
    n-propyl acetate 0.47
    acetic acid 14.61
    dichloromethane 1.56
    cyclohexanone 3.69
    propylene glycol 7.51
    isopropyl acetate 0.67
    DMAc 28.07
    2-ethoxyethanol 8.61
    isopentanol 0.66
    n-heptane 0.05
    ethyl formate 1.99
    1,2-dichloroethane 0.96
    n-hexanol 0.4
    2-methoxyethanol 23.89
    isobutyl acetate 0.18
    tetrachloromethane 0.17
    n-pentyl acetate 0.97
    transcutol 12.14
    n-heptanol 0.82
    ethylbenzene 0.11
    MIBK 0.61
    2-propoxyethanol 4.76
    tert-butanol 0.64
    MTBE 0.44
    2-butoxyethanol 4.17
    propionic acid 3.48
    o-xylene 0.26
    formic acid 25.47
    diethyl ether 1.09
    m-xylene 0.22
    p-xylene 0.11
    chlorobenzene 0.26
    dimethyl carbonate 4.11
    n-octane 0.04
    formamide 20.48
    cyclopentanone 7.33
    2-pentanone 1.89
    anisole 0.63
    cyclopentyl methyl ether 2.11
    gamma-butyrolactone 9.81
    1-methoxy-2-propanol 12.15
    pyridine 3.26
    3-pentanone 1.47
    furfural 9.23
    n-dodecane 0.03
    diethylene glycol 8.03
    diisopropyl ether 0.13
    tert-amyl alcohol 0.67
    acetylacetone 3.77
    n-hexadecane 0.03
    acetophenone 0.9
    methyl propionate 2.89
    isopentyl acetate 0.21
    trichloroethylene 2.05
    n-nonanol 0.79
    cyclohexanol 1.08
    benzyl alcohol 1.28
    2-ethylhexanol 0.19
    isooctanol 0.44
    dipropyl ether 0.53
    1,2-dichlorobenzene 0.25
    ethyl lactate 1.35
    propylene carbonate 2.2
    n-methylformamide 12.94
    2-pentanol 0.65
    n-pentane 0.04
    1-propoxy-2-propanol 2.58
    1-methoxy-2-propyl acetate 1.34
    2-(2-methoxypropoxy) propanol 2.98
    mesitylene 0.1
    ε-caprolactone 3.81
    p-cymene 0.08
    epichlorohydrin 7.52
    1,1,1-trichloroethane 0.28
    2-aminoethanol 7.02
    morpholine-4-carbaldehyde 26.17
    sulfolane 22.9
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 2.62
    n-hexyl acetate 1.04
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 5.05
    sec-butyl acetate 0.25
    tert-butyl acetate 0.56
    decalin 0.01
    glycerin 20.77
    diglyme 8.94
    acrylic acid 6.71
    isopropyl myristate 0.29
    n-butyric acid 3.08
    acetyl acetate 1.3
    di(2-ethylhexyl) phthalate 0.49
    ethyl propionate 0.59
    nitromethane 19.12
    1,2-diethoxyethane 1.69
    benzonitrile 0.5
    trioctyl phosphate 0.41
    1-bromopropane 0.34
    gamma-valerolactone 21.14
    n-decanol 0.49
    triethyl phosphate 0.33
    4-methyl-2-pentanol 0.22
    propionitrile 0.75
    vinylene carbonate 2.83
    1,1,2-trichlorotrifluoroethane 14.67
    DMS 1.22
    cumene 0.06
    2-octanol 0.48
    2-hexanone 0.63
    octyl acetate 0.6
    limonene 0.14
    1,2-dimethoxyethane 6.85
    ethyl orthosilicate 0.31
    tributyl phosphate 0.31
    diacetone alcohol 2.5
    N,N-dimethylaniline 0.51
    acrylonitrile 1.66
    aniline 1.12
    1,3-propanediol 7.63
    bromobenzene 0.18
    dibromomethane 0.6
    1,1,2,2-tetrachloroethane 1.85
    2-methyl-cyclohexyl acetate 0.28
    tetrabutyl urea 0.72
    diisobutyl methanol 0.12
    2-phenylethanol 0.62
    styrene 0.14
    dioctyl adipate 0.68
    dimethyl sulfate 9.67
    ethyl butyrate 0.39
    methyl lactate 7.3
    butyl lactate 1.64
    diethyl carbonate 0.25
    propanediol butyl ether 5.6
    triethyl orthoformate 0.49
    p-tert-butyltoluene 0.08
    methyl 4-tert-butylbenzoate 1.71
    morpholine 10.39
    tert-butylamine 0.18
    n-dodecanol 0.3
    dimethoxymethane 14.64
    ethylene carbonate 1.86
    cyrene 5.96
    2-ethoxyethyl acetate 2.5
    2-ethylhexyl acetate 0.16
    1,2,4-trichlorobenzene 0.42
    4-methylpyridine 1.69
    dibutyl ether 0.46
    2,6-dimethyl-4-heptanol 0.12
    DEF 4.52
    dimethyl isosorbide 3.74
    tetrachloroethylene 1.32
    eugenol 1.87
    triacetin 2.29
    span 80 3.22
    1,4-butanediol 2.75
    1,1-dichloroethane 0.43
    2-methyl-1-pentanol 0.41
    methyl formate 10.56
    2-methyl-1-butanol 0.75
    n-decane 0.06
    butyronitrile 0.64
    3,7-dimethyl-1-octanol 0.29
    1-chlorooctane 0.2
    1-chlorotetradecane 0.06
    n-nonane 0.05
    undecane 0.04
    tert-butylcyclohexane 0.01
    cyclooctane 0.03
    cyclopentanol 1.81
    tetrahydropyran 2.49
    tert-amyl methyl ether 0.59
    2,5,8-trioxanonane 6.41
    1-hexene 0.06
    2-isopropoxyethanol 2.82
    2,2,2-trifluoroethanol 6.71
    methyl butyrate 0.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction