Lauryl Hydroxysultaine

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  • Identifiers

    CAS number
    13197-76-7

    Molecular formula
    C17H37NO4S

    SMILES
    CCCCCCCCCCCC[N+](C)(C)CC(CS(=O)(=O)[O-])O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 44.41%
    Fatty 34.47%
    Waxy 28.75%
    Citrus 26.19%
    Savory 25.0%
    Fresh 23.6%
    Meaty 22.03%
    Oily 20.47%
    Animal 20.41%
    Milky 19.15%

     

    Flavor
    Bland 33.97%
    Bitter 26.18%
    Mild 25.14%
    Odorless 22.73%
    Delicate 19.57%
    Slightly waxy 19.33%
    Cedarleaf 19.27%
    Oriental 18.83%
    Diterpene 18.72%
    Bay oil 18.6%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.1

    pKa est.
    4.86 (weak acid)

    Molecular weight
    351.5 g/mol

    Flash point

    • -24.27 ˚C est.

  • Synonyms

    • Lauryl hydroxysultaine
    • UNII-176KKP31OZ
    • 176KKP31OZ
    • ORISTAR LHS
    • MACKAM LHS
    • 1-Dodecanaminium, N-(2-hydroxy-3-sulfopropyl)-N,N-dimethyl-, inner salt
    • EINECS 236-164-7
    • OBAZOLIN AHS-103
    • 1-Dodecanaminium, N-(2-hydroxy-3-sulfopropyl)-N,N-dimethyl-, hydroxide, inner salt
    • DTXSID2050035
    • LAURYL HYDROXYSULFOBETAINE
    • Dimethyl (2-hydroxy-3-sulfopropyl)dodecylammonium hydroxide, inner salt
    • Dodecyl(2-hydroxy-3-sulphonatopropyl)dimethylammonium
    • DODECYL(2-HYDROXY-3-SULFOPROPYL)DIMETHYLAMMONIUM HYDROXIDE, INNER SALT
    • 3-(N,N-DIMETHYL-N-DODECYLAMMONIO)-2-HYDROXYPROPANE-1-SULFONATE
    • (2-HYDROXY-3-SULFOPROPYL)LAURYLDIMETHYLAMMONIUM HYDROXIDE INNER SALT
    • N,N-DIMETHYL-N-LAURYL-N-(2-HYDROXY-1-SULFOPROPYL)AMMONIUM SULFOBETAINE
    • N-LAURYL-N,N-DIMETHYL-N-(2-HYDROXY-3-SULFOPROPYL)AMMONIUM SULFOBETAINE
    • AMMONIUM, DODECYL(2-HYDROXY-3-SULFOPROPYL)DIMETHYL-, HYDROXIDE, INNER SALT
    • N-DODECYL-N,N-DIMETHYL-N-(2-HYDROXY-1-SULFOPROPYL)AMMONIUM SULFOBETAINE
    • RefChem:152530
    • DTXCID7029825
    • (+-)-LAURYL HYDROXYSULTAINE
    • LAURYL HYDROXYSULTAINE [INCI]
    • LAURYL HYDROXYSULTAINE, (+-)-
    • 13197-76-7
    • N,N-Dimethyl-N-dodecyl-N-(2-hydroxy-3-sulfopropyl)ammonium betaine
    • 3-(Dodecyldimethylammonio)-2-hydroxypropane-1-sulfonate
    • 3-[dodecyl(dimethyl)azaniumyl]-2-hydroxypropane-1-sulfonate
    • 3-(dodecyldimethylazaniumyl)-2-hydroxypropane-1-sulfonate
    • orb2942310
    • SCHEMBL6242017
    • DDGPBVIAYDDWDH-UHFFFAOYSA-N
    • (+/-)-LAURYL HYDROXYSULTAINE
    • HY-W683499
    • LAURYL HYDROXYSULTAINE, (+/-)-
    • CS-0767308
    • Q27251880
    • 3-[Dodecyldi(methyl)azaniumyl]-2-hydroxypropane-1-sulfonate
    • 13197-76-7

  • Applications

    Lauryl Hydroxysultaine (CAS 13197-76-7) is a mild amphoteric surfactant used as a foaming, emulsifying, and cleansing agent across several industries. In cosmetics and personal care, it provides gentle cleansing and foam in shampoos, body washes, and facial cleansers. In household products, it serves as a primary or auxiliary surfactant in dishwashing liquids and all‑purpose cleaners. In industrial cleaning formulations, it offers wetting and emulsification to improve degreasers and general cleaners. In coatings and inks, it functions as a dispersant and wetting agent to enhance pigment dispersion and surface wetting. In polymers and plastics, it can act as an emulsifier or compatibility additive in polymer emulsions and latex formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 14.58
    methanol 48.24
    isopropanol 3.89
    water 1.45
    ethyl acetate 5.69
    n-propanol 10.16
    acetone 9.1
    n-butanol 6.17
    acetonitrile 3.88
    DMF 51.21
    toluene 5.42
    isobutanol 5.95
    1,4-dioxane 10.49
    methyl acetate 6.31
    THF 37.05
    2-butanone 7.81
    n-pentanol 5.3
    sec-butanol 4.55
    n-hexane 0.28
    ethylene glycol 10.28
    NMP 243.88
    cyclohexane 1.2
    DMSO 69.21
    n-butyl acetate 11.5
    n-octanol 5.6
    chloroform 34.01
    n-propyl acetate 10.25
    acetic acid 63.17
    dichloromethane 31.11
    cyclohexanone 48.26
    propylene glycol 17.76
    isopropyl acetate 5.46
    DMAc 75.81
    2-ethoxyethanol 24.57
    isopentanol 5.5
    n-heptane 0.45
    ethyl formate 9.85
    1,2-dichloroethane 17.61
    n-hexanol 6.71
    2-methoxyethanol 41.77
    isobutyl acetate 8.07
    tetrachloromethane 4.83
    n-pentyl acetate 13.75
    transcutol 115.06
    n-heptanol 7.21
    ethylbenzene 3.84
    MIBK 7.82
    2-propoxyethanol 32.03
    tert-butanol 4.92
    MTBE 2.05
    2-butoxyethanol 31.45
    propionic acid 24.77
    o-xylene 6.92
    formic acid 62.12
    diethyl ether 1.71
    m-xylene 6.97
    p-xylene 5.18
    chlorobenzene 9.75
    dimethyl carbonate 8.29
    n-octane 0.28
    formamide 68.97
    cyclopentanone 73.64
    2-pentanone 7.63
    anisole 8.14
    cyclopentyl methyl ether 18.87
    gamma-butyrolactone 91.14
    1-methoxy-2-propanol 27.75
    pyridine 21.5
    3-pentanone 7.29
    furfural 87.47
    n-dodecane 0.2
    diethylene glycol 33.31
    diisopropyl ether 1.04
    tert-amyl alcohol 5.94
    acetylacetone 18.34
    n-hexadecane 0.23
    acetophenone 22.63
    methyl propionate 10.13
    isopentyl acetate 12.59
    trichloroethylene 56.29
    n-nonanol 5.64
    cyclohexanol 13.48
    benzyl alcohol 15.94
    2-ethylhexanol 5.59
    isooctanol 6.56
    dipropyl ether 3.65
    1,2-dichlorobenzene 15.3
    ethyl lactate 16.63
    propylene carbonate 48.0
    n-methylformamide 34.29
    2-pentanol 2.95
    n-pentane 0.28
    1-propoxy-2-propanol 23.14
    1-methoxy-2-propyl acetate 23.02
    2-(2-methoxypropoxy) propanol 35.32
    mesitylene 4.64
    ε-caprolactone 54.99
    p-cymene 4.9
    epichlorohydrin 50.44
    1,1,1-trichloroethane 12.88
    2-aminoethanol 24.84
    morpholine-4-carbaldehyde 98.59
    sulfolane 226.53
    2,2,4-trimethylpentane 0.38
    2-methyltetrahydrofuran 17.95
    n-hexyl acetate 14.99
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 43.46
    sec-butyl acetate 6.72
    tert-butyl acetate 9.98
    decalin 0.94
    glycerin 45.78
    diglyme 64.81
    acrylic acid 35.25
    isopropyl myristate 4.73
    n-butyric acid 24.96
    acetyl acetate 8.32
    di(2-ethylhexyl) phthalate 13.81
    ethyl propionate 7.71
    nitromethane 53.07
    1,2-diethoxyethane 9.22
    benzonitrile 13.62
    trioctyl phosphate 8.04
    1-bromopropane 4.56
    gamma-valerolactone 117.53
    n-decanol 3.61
    triethyl phosphate 10.96
    4-methyl-2-pentanol 2.77
    propionitrile 4.22
    vinylene carbonate 42.63
    1,1,2-trichlorotrifluoroethane 124.72
    DMS 16.18
    cumene 3.61
    2-octanol 3.9
    2-hexanone 8.38
    octyl acetate 7.33
    limonene 6.36
    1,2-dimethoxyethane 20.01
    ethyl orthosilicate 10.12
    tributyl phosphate 9.57
    diacetone alcohol 25.11
    N,N-dimethylaniline 10.75
    acrylonitrile 9.26
    aniline 12.49
    1,3-propanediol 19.74
    bromobenzene 9.08
    dibromomethane 16.25
    1,1,2,2-tetrachloroethane 45.18
    2-methyl-cyclohexyl acetate 20.71
    tetrabutyl urea 15.65
    diisobutyl methanol 3.13
    2-phenylethanol 17.47
    styrene 3.85
    dioctyl adipate 13.57
    dimethyl sulfate 32.8
    ethyl butyrate 10.01
    methyl lactate 22.36
    butyl lactate 27.25
    diethyl carbonate 7.73
    propanediol butyl ether 37.39
    triethyl orthoformate 10.95
    p-tert-butyltoluene 4.69
    methyl 4-tert-butylbenzoate 34.51
    morpholine 22.14
    tert-butylamine 2.21
    n-dodecanol 2.3
    dimethoxymethane 16.48
    ethylene carbonate 28.17
    cyrene 69.23
    2-ethoxyethyl acetate 21.4
    2-ethylhexyl acetate 10.81
    1,2,4-trichlorobenzene 24.09
    4-methylpyridine 17.02
    dibutyl ether 2.97
    2,6-dimethyl-4-heptanol 3.13
    DEF 19.04
    dimethyl isosorbide 78.66
    tetrachloroethylene 35.83
    eugenol 38.29
    triacetin 36.24
    span 80 35.21
    1,4-butanediol 8.37
    1,1-dichloroethane 8.4
    2-methyl-1-pentanol 5.3
    methyl formate 21.12
    2-methyl-1-butanol 6.2
    n-decane 0.39
    butyronitrile 3.81
    3,7-dimethyl-1-octanol 5.38
    1-chlorooctane 2.32
    1-chlorotetradecane 0.8
    n-nonane 0.34
    undecane 0.27
    tert-butylcyclohexane 0.64
    cyclooctane 0.56
    cyclopentanol 19.24
    tetrahydropyran 9.66
    tert-amyl methyl ether 3.37
    2,5,8-trioxanonane 50.84
    1-hexene 1.09
    2-isopropoxyethanol 15.01
    2,2,2-trifluoroethanol 35.63
    methyl butyrate 12.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction