Lauric isopropanolamide

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  • Identifiers

    CAS number
    142-54-1

    Molecular formula
    C15H31NO2

    SMILES
    CCCCCCCCCCCC(=O)NCC(C)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Savory 36.06%
    Meaty 35.33%
    Cooling 30.64%
    Odorless 30.42%
    Citrus 29.76%
    Fishy 28.6%
    Fatty 28.19%
    Fresh 26.32%
    Mint 26.17%
    Oily 25.91%

     

    Flavor
    Mild 33.67%
    Odorless 32.83%
    Bland 30.56%
    Fatty 29.75%
    Waxy 25.59%
    Herbal 25.37%
    Oily 24.16%
    Slightly waxy 22.19%
    Bay oil 21.84%
    Faint 21.72%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.4

    pKa est.
    7.81 (neutral)

    Molecular weight
    257.41 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    370°C

    Flash point

    • 172.21 ˚C est.

  • Synonyms

    • N-(2-Hydroxypropyl)dodecanamide
    • 142-54-1
    • Lauramide MIPA
    • LAURIC ISOPROPANOLAMIDE
    • Lauroyl isopropanolamide
    • Dodecanamide, N-(2-hydroxypropyl)-
    • 82DUX3RRVU
    • EINECS 205-541-8
    • Monoisopropanolamine lauric acid amide
    • LAURYL MONOISOPROPANOLAMIDE
    • DTXSID00861815
    • LAURAMIDE MONOISOPROPANOLAMIDE (MIPA)
    • RefChem:798563
    • LAURAMIDE MIPA [INCI]
    • DTXCID80810689
    • 205-541-8
    • Dodecanamide,N-(2-hydroxypropyl)-
    • UNII-82DUX3RRVU
    • SCHEMBL1498601
    • CHEBI:182549
    • MMBILEWCGWTAOV-UHFFFAOYSA-N
    • AKOS010638772
    • NS00014428
    • G51881
    • EN300-15133346
    • Q27269328
    • Z808916620
    • 142-54-1

  • Applications

    Lauric isopropanolamide (CAS 142-54-1) is primarily used as a nonionic surfactant and emulsifier in cosmetic and personal-care formulations, providing cleansing, foaming, and conditioning properties; it is also employed as a surfactant and emulsifier in household cleaners and other cleaning products; in industrial manufacturing, it can serve as a processing aid and dispersing/emulsifying additive in formulations such as metalworking fluids and lubricants; in coatings and inks, it may act as an emulsifier and stabilizer for waterborne systems; and in polymer or plastics processing, it can function as a processing aid or compatibilizer to improve mixtures of polar and nonpolar components in polymer systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 590.45
    methanol 984.61
    isopropanol 470.92
    water 0.14
    ethyl acetate 312.82
    n-propanol 418.49
    acetone 471.64
    n-butanol 384.16
    acetonitrile 147.45
    DMF 543.95
    toluene 66.97
    isobutanol 326.87
    1,4-dioxane 359.17
    methyl acetate 197.46
    THF 873.15
    2-butanone 343.44
    n-pentanol 287.81
    sec-butanol 339.96
    n-hexane 24.28
    ethylene glycol 44.77
    NMP 461.45
    cyclohexane 44.83
    DMSO 1048.82
    n-butyl acetate 351.76
    n-octanol 111.68
    chloroform 451.21
    n-propyl acetate 375.11
    acetic acid 337.82
    dichloromethane 390.62
    cyclohexanone 665.54
    propylene glycol 130.42
    isopropyl acetate 305.38
    DMAc 554.18
    2-ethoxyethanol 466.05
    isopentanol 401.19
    n-heptane 15.25
    ethyl formate 219.08
    1,2-dichloroethane 318.05
    n-hexanol 236.65
    2-methoxyethanol 630.22
    isobutyl acetate 273.59
    tetrachloromethane 83.31
    n-pentyl acetate 274.53
    transcutol 1116.67
    n-heptanol 128.39
    ethylbenzene 57.31
    MIBK 290.42
    2-propoxyethanol 422.16
    tert-butanol 547.3
    MTBE 388.14
    2-butoxyethanol 307.94
    propionic acid 248.02
    o-xylene 71.09
    formic acid 106.35
    diethyl ether 246.18
    m-xylene 62.98
    p-xylene 84.59
    chlorobenzene 124.16
    dimethyl carbonate 59.01
    n-octane 7.92
    formamide 129.05
    cyclopentanone 631.34
    2-pentanone 365.54
    anisole 140.28
    cyclopentyl methyl ether 346.03
    gamma-butyrolactone 579.77
    1-methoxy-2-propanol 499.53
    pyridine 274.06
    3-pentanone 192.82
    furfural 463.12
    n-dodecane 5.68
    diethylene glycol 241.24
    diisopropyl ether 76.63
    tert-amyl alcohol 404.65
    acetylacetone 388.1
    n-hexadecane 6.69
    acetophenone 184.79
    methyl propionate 186.45
    isopentyl acetate 347.04
    trichloroethylene 479.04
    n-nonanol 99.24
    cyclohexanol 355.39
    benzyl alcohol 153.97
    2-ethylhexanol 158.77
    isooctanol 120.21
    dipropyl ether 179.34
    1,2-dichlorobenzene 139.92
    ethyl lactate 152.47
    propylene carbonate 368.54
    n-methylformamide 245.16
    2-pentanol 245.11
    n-pentane 13.41
    1-propoxy-2-propanol 347.39
    1-methoxy-2-propyl acetate 296.54
    2-(2-methoxypropoxy) propanol 212.3
    mesitylene 48.34
    ε-caprolactone 545.2
    p-cymene 48.1
    epichlorohydrin 554.21
    1,1,1-trichloroethane 266.54
    2-aminoethanol 175.26
    morpholine-4-carbaldehyde 469.48
    sulfolane 777.95
    2,2,4-trimethylpentane 15.11
    2-methyltetrahydrofuran 550.76
    n-hexyl acetate 281.7
    isooctane 10.37
    2-(2-butoxyethoxy)ethanol 342.86
    sec-butyl acetate 263.38
    tert-butyl acetate 339.61
    decalin 23.53
    glycerin 168.49
    diglyme 642.65
    acrylic acid 151.66
    isopropyl myristate 84.72
    n-butyric acid 564.72
    acetyl acetate 187.04
    di(2-ethylhexyl) phthalate 89.77
    ethyl propionate 245.18
    nitromethane 455.88
    1,2-diethoxyethane 342.57
    benzonitrile 189.81
    trioctyl phosphate 70.48
    1-bromopropane 194.71
    gamma-valerolactone 833.85
    n-decanol 64.89
    triethyl phosphate 108.86
    4-methyl-2-pentanol 155.14
    propionitrile 176.87
    vinylene carbonate 267.01
    1,1,2-trichlorotrifluoroethane 461.16
    DMS 136.7
    cumene 50.64
    2-octanol 92.47
    2-hexanone 337.82
    octyl acetate 109.75
    limonene 85.73
    1,2-dimethoxyethane 740.05
    ethyl orthosilicate 115.94
    tributyl phosphate 94.82
    diacetone alcohol 378.33
    N,N-dimethylaniline 104.79
    acrylonitrile 169.18
    aniline 125.46
    1,3-propanediol 348.24
    bromobenzene 122.04
    dibromomethane 269.97
    1,1,2,2-tetrachloroethane 517.03
    2-methyl-cyclohexyl acetate 195.13
    tetrabutyl urea 122.53
    diisobutyl methanol 90.53
    2-phenylethanol 143.91
    styrene 73.18
    dioctyl adipate 142.32
    dimethyl sulfate 133.31
    ethyl butyrate 250.19
    methyl lactate 134.65
    butyl lactate 236.39
    diethyl carbonate 137.91
    propanediol butyl ether 276.27
    triethyl orthoformate 178.22
    p-tert-butyltoluene 47.4
    methyl 4-tert-butylbenzoate 180.25
    morpholine 616.71
    tert-butylamine 267.03
    n-dodecanol 45.71
    dimethoxymethane 282.72
    ethylene carbonate 264.74
    cyrene 200.87
    2-ethoxyethyl acetate 303.83
    2-ethylhexyl acetate 244.01
    1,2,4-trichlorobenzene 162.28
    4-methylpyridine 274.79
    dibutyl ether 177.07
    2,6-dimethyl-4-heptanol 90.53
    DEF 388.63
    dimethyl isosorbide 346.85
    tetrachloroethylene 346.49
    eugenol 176.14
    triacetin 262.86
    span 80 208.12
    1,4-butanediol 135.63
    1,1-dichloroethane 278.1
    2-methyl-1-pentanol 256.28
    methyl formate 141.38
    2-methyl-1-butanol 306.2
    n-decane 12.08
    butyronitrile 266.72
    3,7-dimethyl-1-octanol 119.49
    1-chlorooctane 68.82
    1-chlorotetradecane 21.05
    n-nonane 11.39
    undecane 7.65
    tert-butylcyclohexane 21.82
    cyclooctane 10.61
    cyclopentanol 373.02
    tetrahydropyran 558.69
    tert-amyl methyl ether 243.32
    2,5,8-trioxanonane 380.38
    1-hexene 120.88
    2-isopropoxyethanol 337.81
    2,2,2-trifluoroethanol 97.14
    methyl butyrate 418.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction