Lactoscatone

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  • Identifiers

    CAS number
    21280-29-5

    Molecular formula
    C14H22O2

    SMILES
    CC1(CCCC23C1CC(CC2)(C(=O)O3)C)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Woody 67.47%
    Amber 50.35%
    Musk 46.06%
    Dry 45.39%
    Cedar 42.86%
    Animal 40.29%
    Tobacco 40.03%
    Spicy 36.35%
    Camphoreous 34.78%
    Earthy 29.11%

     

    Flavor
    Camphor 36.49%
    Herbal 31.96%
    Bitter 31.29%
    Minty 31.02%
    Earthy 29.18%
    Woody 29.18%
    Earth 24.88%
    Fresh 24.7%
    Musk 24.5%
    Ripe apricot 24.49%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    7.81 (neutral)

    Molecular weight
    222.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    333°C

    Flash point

    • 154.93 ˚C est.

  • Synonyms

    • Lactoscatone
    • 21280-29-5
    • 3,8a-Ethano-8aH-1-benzopyran-2(3H)-one, hexahydro-3,5,5-trimethyl-
    • Decahydro-2,8,8-trimethylnaphthalene-2,4a-carbolactone
    • EINECS 244-310-6
    • 5,5,8-trimethyl-10-oxatricyclo[6.2.2.01,6]dodecan-9-one
    • DTXSID60864983
    • Hydroxy-4,7,7-trimethyl-4-carboxylic acid-lactone
    • Hexahydro-3,5,5-trimethyl-3,8a-ethano-8aH-1-benzopyran-2(3H)-one
    • 1-Hydroxy-4,7,7-trimethylbicyclo(4.4.0)decane-4-carboxylic acid lactone
    • Decahydro-4-alpha-hydroxy-2,8,8-trimethyl-2-naphthoic acid, gamma-lactone
    • SCHEMBL3508518
    • DTXCID10813441
    • TUVXRDNMAFEUBI-UHFFFAOYSA-N
    • AKOS040752382
    • NS00012781
    • 244-310-6

  • Applications

    Lactoscatone (CAS 21280-29-5) may be used primarily as a fragrance ingredient in perfumery and personal care, acting as an odorant or aroma component that contributes specific notes. It can also serve as an intermediate in fragrance synthesis, supporting the development of more complex scent profiles. In household products, it is used to impart pleasant fragrance to cleaners, detergents, and air fresheners. In polymers, plastics, and coatings, Lactoscatone may function as a specialty intermediate or fragrance additive for finished materials and surface coatings. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 41.05
    methanol 46.13
    isopropanol 48.66
    water 0.97
    ethyl acetate 123.71
    n-propanol 50.72
    acetone 157.03
    n-butanol 45.47
    acetonitrile 85.96
    DMF 296.9
    toluene 171.41
    isobutanol 48.63
    1,4-dioxane 222.77
    methyl acetate 158.92
    THF 346.9
    2-butanone 181.35
    n-pentanol 35.7
    sec-butanol 42.39
    n-hexane 3.17
    ethylene glycol 23.98
    NMP 344.24
    cyclohexane 11.27
    DMSO 149.03
    n-butyl acetate 136.31
    n-octanol 57.05
    chloroform 549.38
    n-propyl acetate 100.21
    acetic acid 82.39
    dichloromethane 387.26
    cyclohexanone 316.38
    propylene glycol 31.49
    isopropyl acetate 106.9
    DMAc 256.68
    2-ethoxyethanol 67.63
    isopentanol 48.74
    n-heptane 5.76
    ethyl formate 113.42
    1,2-dichloroethane 202.98
    n-hexanol 69.9
    2-methoxyethanol 111.63
    isobutyl acetate 89.95
    tetrachloromethane 63.16
    n-pentyl acetate 117.25
    transcutol 202.08
    n-heptanol 58.68
    ethylbenzene 84.73
    MIBK 107.65
    2-propoxyethanol 144.34
    tert-butanol 56.1
    MTBE 54.87
    2-butoxyethanol 104.89
    propionic acid 100.21
    o-xylene 129.22
    formic acid 30.45
    diethyl ether 49.22
    m-xylene 141.14
    p-xylene 131.57
    chlorobenzene 217.78
    dimethyl carbonate 92.51
    n-octane 4.98
    formamide 55.41
    cyclopentanone 406.06
    2-pentanone 123.08
    anisole 132.64
    cyclopentyl methyl ether 124.57
    gamma-butyrolactone 451.49
    1-methoxy-2-propanol 110.57
    pyridine 288.11
    3-pentanone 117.4
    furfural 382.09
    n-dodecane 7.03
    diethylene glycol 112.69
    diisopropyl ether 29.01
    tert-amyl alcohol 46.02
    acetylacetone 199.61
    n-hexadecane 8.43
    acetophenone 170.05
    methyl propionate 132.12
    isopentyl acetate 145.31
    trichloroethylene 491.03
    n-nonanol 55.65
    cyclohexanol 74.83
    benzyl alcohol 116.01
    2-ethylhexanol 57.2
    isooctanol 54.09
    dipropyl ether 45.29
    1,2-dichlorobenzene 221.58
    ethyl lactate 75.77
    propylene carbonate 280.87
    n-methylformamide 130.6
    2-pentanol 33.39
    n-pentane 4.37
    1-propoxy-2-propanol 111.44
    1-methoxy-2-propyl acetate 174.33
    2-(2-methoxypropoxy) propanol 126.87
    mesitylene 90.32
    ε-caprolactone 273.84
    p-cymene 75.06
    epichlorohydrin 346.41
    1,1,1-trichloroethane 221.22
    2-aminoethanol 38.17
    morpholine-4-carbaldehyde 339.14
    sulfolane 408.61
    2,2,4-trimethylpentane 5.6
    2-methyltetrahydrofuran 179.27
    n-hexyl acetate 153.39
    isooctane 6.02
    2-(2-butoxyethoxy)ethanol 132.34
    sec-butyl acetate 85.02
    tert-butyl acetate 117.14
    decalin 13.13
    glycerin 56.09
    diglyme 219.37
    acrylic acid 114.78
    isopropyl myristate 76.05
    n-butyric acid 113.42
    acetyl acetate 126.38
    di(2-ethylhexyl) phthalate 95.46
    ethyl propionate 96.1
    nitromethane 207.94
    1,2-diethoxyethane 91.26
    benzonitrile 217.55
    trioctyl phosphate 69.92
    1-bromopropane 85.91
    gamma-valerolactone 466.68
    n-decanol 45.08
    triethyl phosphate 74.08
    4-methyl-2-pentanol 35.25
    propionitrile 96.96
    vinylene carbonate 314.34
    1,1,2-trichlorotrifluoroethane 221.62
    DMS 192.44
    cumene 68.4
    2-octanol 46.27
    2-hexanone 98.7
    octyl acetate 95.31
    limonene 79.04
    1,2-dimethoxyethane 122.28
    ethyl orthosilicate 64.45
    tributyl phosphate 76.59
    diacetone alcohol 118.06
    N,N-dimethylaniline 99.73
    acrylonitrile 156.03
    aniline 138.38
    1,3-propanediol 54.18
    bromobenzene 232.2
    dibromomethane 217.79
    1,1,2,2-tetrachloroethane 362.42
    2-methyl-cyclohexyl acetate 118.92
    tetrabutyl urea 100.4
    diisobutyl methanol 43.38
    2-phenylethanol 151.93
    styrene 91.27
    dioctyl adipate 105.01
    dimethyl sulfate 169.18
    ethyl butyrate 102.72
    methyl lactate 95.84
    butyl lactate 105.79
    diethyl carbonate 84.38
    propanediol butyl ether 97.77
    triethyl orthoformate 81.23
    p-tert-butyltoluene 71.34
    methyl 4-tert-butylbenzoate 177.66
    morpholine 187.05
    tert-butylamine 34.31
    n-dodecanol 36.35
    dimethoxymethane 150.55
    ethylene carbonate 234.2
    cyrene 154.96
    2-ethoxyethyl acetate 161.72
    2-ethylhexyl acetate 123.51
    1,2,4-trichlorobenzene 263.53
    4-methylpyridine 276.45
    dibutyl ether 48.95
    2,6-dimethyl-4-heptanol 43.38
    DEF 139.01
    dimethyl isosorbide 252.93
    tetrachloroethylene 217.86
    eugenol 155.71
    triacetin 182.7
    span 80 119.9
    1,4-butanediol 30.43
    1,1-dichloroethane 206.04
    2-methyl-1-pentanol 43.16
    methyl formate 135.96
    2-methyl-1-butanol 44.23
    n-decane 9.91
    butyronitrile 85.86
    3,7-dimethyl-1-octanol 65.35
    1-chlorooctane 45.34
    1-chlorotetradecane 23.64
    n-nonane 7.86
    undecane 8.16
    tert-butylcyclohexane 11.53
    cyclooctane 5.97
    cyclopentanol 95.52
    tetrahydropyran 153.05
    tert-amyl methyl ether 47.54
    2,5,8-trioxanonane 164.37
    1-hexene 16.91
    2-isopropoxyethanol 64.63
    2,2,2-trifluoroethanol 64.43
    methyl butyrate 119.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction