Laccase

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  • Identifiers

    CAS number
    80498-15-3

    Molecular formula
    C9H13NO

    SMILES
    CCN1C(=CC(=C1C)C=O)C

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Roasted 46.96%
    Nutty 38.52%
    Burnt 38.09%
    Earthy 36.4%
    Musty 33.62%
    Hazelnut 30.01%
    Animal 27.1%
    Popcorn 26.68%
    Sweet 26.34%
    Meaty 24.17%

     

    Flavor
    Nutty 34.1%
    Bitter 32.61%
    Roasted 29.55%
    Cocoa 28.06%
    Musty 27.52%
    Burnt 26.36%
    Woody 24.05%
    Earthy 23.85%
    Hazelnut 23.06%
    Soybean 22.74%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    6.82 (neutral)

    Molecular weight
    151.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    327°C

    Flash point

    • 98.19 ˚C est.

  • Synonyms

    • Laccase
    • 80498-15-3
    • Denilase II S
    • Urushiol oxidase
    • Novozyme 809
    • urishiol oxidase
    • Oxidase, Urishiol
    • p Diphenol Oxidase
    • Oxidase, p-Diphenol
    • SP 504
    • RefChem:798342
    • EC 420-150-4
    • E.C. 1.10.3.2
    • DTXSID30108720
    • 420-150-4
    • 617-092-9
    • 1-Ethyl-2,5-dimethyl-1H-pyrrole-3-carbaldehyde
    • 18870-74-1
    • 1-ethyl-2,5-dimethylpyrrole-3-carbaldehyde
    • MFCD00192997
    • 1-ethyl-2,5-dimethyl-pyrrole-3-carbaldehyde
    • SCHEMBL14232240
    • DTXSID40390018
    • TAA87074
    • MFCD00131475
    • SBB010326
    • STL289230
    • AKOS000113202
    • SB62200
    • ST076738
    • SY275703
    • DB-363579
    • CS-0257712
    • EN300-67599
    • G32278
    • Z295454930
    • 80498-15-3

  • Applications

    Laccase (CAS 80498-15-3) is a multicopper oxidase enzyme produced by fungi and other microorganisms, functioning as a biocatalyst that oxidizes phenolic substrates with O2 reduced to water. Its real-world applications include pulping and papermaking bleaching/biobleaching to delignify wood pulp; oxidative decolorization of dyes in textile wastewater; bioremediation and detoxification of phenolic pollutants in water and soils; green biocatalysis for organic synthesis and oxidative coupling in coatings, inks, and adhesives; pretreatment of lignocellulosic biomass to improve saccharification and subsequent biofuel production; use in biosensors for detecting phenolic compounds; and immobilized-enzyme reactor systems for scalable, reusable processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 208.35
    methanol 319.09
    isopropanol 123.55
    water 20.71
    ethyl acetate 261.39
    n-propanol 183.75
    acetone 307.47
    n-butanol 171.16
    acetonitrile 323.7
    DMF 436.71
    toluene 219.45
    isobutanol 140.56
    1,4-dioxane 557.36
    methyl acetate 279.31
    THF 885.68
    2-butanone 266.71
    n-pentanol 98.37
    sec-butanol 124.17
    n-hexane 22.05
    ethylene glycol 106.05
    NMP 783.1
    cyclohexane 54.34
    DMSO 533.27
    n-butyl acetate 172.93
    n-octanol 48.77
    chloroform 1051.01
    n-propyl acetate 111.93
    acetic acid 243.3
    dichloromethane 1528.5
    cyclohexanone 580.41
    propylene glycol 68.57
    isopropyl acetate 138.6
    DMAc 332.48
    2-ethoxyethanol 174.06
    isopentanol 143.09
    n-heptane 17.77
    ethyl formate 218.54
    1,2-dichloroethane 862.74
    n-hexanol 133.7
    2-methoxyethanol 352.66
    isobutyl acetate 79.34
    tetrachloromethane 232.28
    n-pentyl acetate 100.58
    transcutol 359.37
    n-heptanol 54.14
    ethylbenzene 85.44
    MIBK 120.17
    2-propoxyethanol 257.84
    tert-butanol 145.27
    MTBE 160.84
    2-butoxyethanol 112.88
    propionic acid 193.41
    o-xylene 132.28
    formic acid 223.37
    diethyl ether 213.35
    m-xylene 148.59
    p-xylene 110.88
    chlorobenzene 411.35
    dimethyl carbonate 128.34
    n-octane 7.73
    formamide 300.34
    cyclopentanone 714.46
    2-pentanone 216.79
    anisole 183.97
    cyclopentyl methyl ether 371.37
    gamma-butyrolactone 914.05
    1-methoxy-2-propanol 210.35
    pyridine 477.11
    3-pentanone 202.36
    furfural 652.45
    n-dodecane 7.36
    diethylene glycol 231.27
    diisopropyl ether 60.79
    tert-amyl alcohol 134.04
    acetylacetone 258.69
    n-hexadecane 8.72
    acetophenone 165.39
    methyl propionate 242.82
    isopentyl acetate 158.97
    trichloroethylene 1373.04
    n-nonanol 45.01
    cyclohexanol 231.4
    benzyl alcohol 138.87
    2-ethylhexanol 79.65
    isooctanol 48.27
    dipropyl ether 86.81
    1,2-dichlorobenzene 376.42
    ethyl lactate 65.19
    propylene carbonate 391.22
    n-methylformamide 330.58
    2-pentanol 96.81
    n-pentane 23.0
    1-propoxy-2-propanol 140.48
    1-methoxy-2-propyl acetate 182.14
    2-(2-methoxypropoxy) propanol 119.12
    mesitylene 87.12
    ε-caprolactone 458.83
    p-cymene 64.03
    epichlorohydrin 1073.58
    1,1,1-trichloroethane 711.16
    2-aminoethanol 142.23
    morpholine-4-carbaldehyde 525.05
    sulfolane 873.24
    2,2,4-trimethylpentane 17.64
    2-methyltetrahydrofuran 614.58
    n-hexyl acetate 124.39
    isooctane 11.79
    2-(2-butoxyethoxy)ethanol 138.35
    sec-butyl acetate 84.07
    tert-butyl acetate 151.83
    decalin 29.61
    glycerin 125.13
    diglyme 269.96
    acrylic acid 210.12
    isopropyl myristate 56.54
    n-butyric acid 249.5
    acetyl acetate 172.62
    di(2-ethylhexyl) phthalate 72.63
    ethyl propionate 127.44
    nitromethane 519.83
    1,2-diethoxyethane 143.87
    benzonitrile 246.65
    trioctyl phosphate 49.25
    1-bromopropane 334.92
    gamma-valerolactone 761.05
    n-decanol 35.48
    triethyl phosphate 80.79
    4-methyl-2-pentanol 60.15
    propionitrile 242.82
    vinylene carbonate 373.9
    1,1,2-trichlorotrifluoroethane 400.21
    DMS 161.8
    cumene 62.32
    2-octanol 38.94
    2-hexanone 119.08
    octyl acetate 70.36
    limonene 94.47
    1,2-dimethoxyethane 276.45
    ethyl orthosilicate 75.94
    tributyl phosphate 64.71
    diacetone alcohol 154.03
    N,N-dimethylaniline 114.85
    acrylonitrile 325.06
    aniline 241.03
    1,3-propanediol 186.41
    bromobenzene 456.99
    dibromomethane 839.77
    1,1,2,2-tetrachloroethane 781.82
    2-methyl-cyclohexyl acetate 124.85
    tetrabutyl urea 79.62
    diisobutyl methanol 46.59
    2-phenylethanol 155.47
    styrene 107.31
    dioctyl adipate 89.33
    dimethyl sulfate 233.73
    ethyl butyrate 118.55
    methyl lactate 103.97
    butyl lactate 73.51
    diethyl carbonate 95.29
    propanediol butyl ether 74.8
    triethyl orthoformate 87.53
    p-tert-butyltoluene 61.69
    methyl 4-tert-butylbenzoate 136.62
    morpholine 551.74
    tert-butylamine 110.65
    n-dodecanol 28.72
    dimethoxymethane 298.04
    ethylene carbonate 309.31
    cyrene 162.69
    2-ethoxyethyl acetate 156.08
    2-ethylhexyl acetate 132.21
    1,2,4-trichlorobenzene 407.45
    4-methylpyridine 454.75
    dibutyl ether 65.74
    2,6-dimethyl-4-heptanol 46.59
    DEF 249.13
    dimethyl isosorbide 264.23
    tetrachloroethylene 569.32
    eugenol 122.44
    triacetin 122.6
    span 80 97.0
    1,4-butanediol 71.94
    1,1-dichloroethane 650.03
    2-methyl-1-pentanol 100.4
    methyl formate 299.73
    2-methyl-1-butanol 147.42
    n-decane 10.87
    butyronitrile 222.87
    3,7-dimethyl-1-octanol 57.68
    1-chlorooctane 51.1
    1-chlorotetradecane 23.63
    n-nonane 10.47
    undecane 8.84
    tert-butylcyclohexane 24.86
    cyclooctane 17.86
    cyclopentanol 287.25
    tetrahydropyran 475.49
    tert-amyl methyl ether 137.35
    2,5,8-trioxanonane 192.77
    1-hexene 63.39
    2-isopropoxyethanol 107.93
    2,2,2-trifluoroethanol 186.21
    methyl butyrate 159.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction