L-Glutamic acid, N-(1-oxohexadecyl)-

Overview IFRA Request a quote

  • Identifiers

    CAS number
    38079-66-2

    Molecular formula
    C21H39NO5

    SMILES
    CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 45.53%
    Savory 35.43%
    Fatty 34.8%
    Waxy 31.04%
    Meaty 29.5%
    Milky 25.37%
    Oily 24.67%
    Lactonic 21.0%
    Cooling 20.95%
    Citrus 20.37%

     

    Flavor
    Odorless 48.46%
    Bland 38.05%
    Mild 36.45%
    Fatty 30.56%
    Faint 26.04%
    Waxy 25.39%
    Slightly waxy 22.12%
    Bay oil 21.96%
    Cultured dairy 21.13%
    Sweet-like 20.29%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.4

    pKa est.
    5.9 (weak acid)

    Molecular weight
    385.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    509°C

    Flash point

    • 262.62 ˚C est.

  • Synonyms

    • Palmitoyl glutamic acid
    • 38079-66-2
    • Palmitoylglutaminic acid
    • N-Palmitoylglutamic acid
    • n-hexadecanoyl-l-glutamic acid
    • Acide palmitoylglutaminique
    • L-Glutamic acid, N-(1-oxohexadecyl)-
    • L-Glutamic acid, N-hexadecanoyl-
    • SZ6S57UTL9
    • N-(1-Oxohexadecyl)-L-glutamic acid
    • DTXSID60191488
    • GLUTAMIC ACID, N-PALMITOYL-, L-
    • RefChem:796311
    • DTXCID70113979
    • PALMITOYL GLUTAMIC ACID [INCI]
    • Palmitoylglutamic acid
    • N-Palmitoyl glutamic acid
    • palmitoyl-L-glutamic acid
    • (2S)-2-(hexadecanoylamino)pentanedioic acid
    • N-hexadecanoyl-glutamic acid
    • (S)-2-Palmitamidopentanedioic acid
    • Glutamic acid palmitamide
    • UNII-SZ6S57UTL9
    • Palmtoyl Glutamic Acid
    • SCHEMBL318616
    • orb1695763
    • CHEBI:165551
    • KMAOMYOPEIRFLB-SFHVURJKSA-N
    • EX-A7615
    • LMFA08020087
    • AKOS030607141
    • MS-26359
    • DB-255908
    • HY-135094
    • CS-0109339
    • NS00013935
    • G13036
    • Q27289470
    • 38079-66-2

  • Applications

    For L-Glutamic acid, N-(1-oxohexadecyl)- (CAS number: 38079-66-2), the long-chain acylated glutamate is primarily applied as a surface-active agent and emulsifier in cosmetics and personal care products, where it can function as a mild surfactant and conditioning additive. It may also serve as a building block or intermediate in the synthesis of biobased polymers and biodegradable plastics, contributing to polymer compatibility or dispersion of hydrophobic components. In coatings and inks, it can act as a dispersant or stabilizer and help adjust rheology and film formation. In household cleaning formulations, it serves as a surfactant/emulsifier to aid soil dispersion and foaming. Additionally, it is evaluated as an intermediate in pharmaceutical and agrochemical syntheses to access more complex amide or ester derivatives, subject to formulation needs and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.47
    methanol 17.61
    isopropanol 4.8
    water 0.35
    ethyl acetate 4.85
    n-propanol 6.88
    acetone 11.73
    n-butanol 4.83
    acetonitrile 2.37
    DMF 96.2
    toluene 2.17
    isobutanol 4.38
    1,4-dioxane 11.47
    methyl acetate 6.63
    THF 43.19
    2-butanone 10.79
    n-pentanol 6.25
    sec-butanol 5.84
    n-hexane 0.57
    ethylene glycol 2.82
    NMP 169.73
    cyclohexane 0.61
    DMSO 163.54
    n-butyl acetate 6.77
    n-octanol 5.14
    chloroform 9.77
    n-propyl acetate 8.49
    acetic acid 22.43
    dichloromethane 10.64
    cyclohexanone 30.57
    propylene glycol 6.76
    isopropyl acetate 6.01
    DMAc 201.35
    2-ethoxyethanol 25.73
    isopentanol 5.02
    n-heptane 0.35
    ethyl formate 6.64
    1,2-dichloroethane 8.67
    n-hexanol 3.77
    2-methoxyethanol 28.06
    isobutyl acetate 5.74
    tetrachloromethane 2.66
    n-pentyl acetate 12.25
    transcutol 91.56
    n-heptanol 5.09
    ethylbenzene 2.83
    MIBK 7.38
    2-propoxyethanol 18.48
    tert-butanol 8.14
    MTBE 6.31
    2-butoxyethanol 22.07
    propionic acid 13.44
    o-xylene 3.92
    formic acid 17.32
    diethyl ether 2.66
    m-xylene 2.49
    p-xylene 4.07
    chlorobenzene 3.09
    dimethyl carbonate 7.28
    n-octane 0.3
    formamide 26.37
    cyclopentanone 42.71
    2-pentanone 8.16
    anisole 6.61
    cyclopentyl methyl ether 12.47
    gamma-butyrolactone 48.71
    1-methoxy-2-propanol 25.2
    pyridine 11.75
    3-pentanone 8.06
    furfural 39.18
    n-dodecane 0.21
    diethylene glycol 14.68
    diisopropyl ether 1.58
    tert-amyl alcohol 10.79
    acetylacetone 16.84
    n-hexadecane 0.24
    acetophenone 13.67
    methyl propionate 8.3
    isopentyl acetate 8.04
    trichloroethylene 17.54
    n-nonanol 5.32
    cyclohexanol 8.26
    benzyl alcohol 8.37
    2-ethylhexanol 3.12
    isooctanol 4.76
    dipropyl ether 3.66
    1,2-dichlorobenzene 5.18
    ethyl lactate 11.22
    propylene carbonate 23.71
    n-methylformamide 24.49
    2-pentanol 3.35
    n-pentane 0.28
    1-propoxy-2-propanol 15.19
    1-methoxy-2-propyl acetate 13.63
    2-(2-methoxypropoxy) propanol 27.51
    mesitylene 1.99
    ε-caprolactone 33.63
    p-cymene 2.29
    epichlorohydrin 29.48
    1,1,1-trichloroethane 7.23
    2-aminoethanol 8.09
    morpholine-4-carbaldehyde 78.07
    sulfolane 151.88
    2,2,4-trimethylpentane 0.54
    2-methyltetrahydrofuran 18.08
    n-hexyl acetate 13.93
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 34.02
    sec-butyl acetate 6.65
    tert-butyl acetate 11.53
    decalin 0.84
    glycerin 15.77
    diglyme 63.96
    acrylic acid 13.76
    isopropyl myristate 4.34
    n-butyric acid 14.16
    acetyl acetate 5.72
    di(2-ethylhexyl) phthalate 8.09
    ethyl propionate 7.54
    nitromethane 31.23
    1,2-diethoxyethane 14.12
    benzonitrile 5.55
    trioctyl phosphate 5.39
    1-bromopropane 3.21
    gamma-valerolactone 75.98
    n-decanol 3.29
    triethyl phosphate 8.58
    4-methyl-2-pentanol 2.91
    propionitrile 2.76
    vinylene carbonate 17.39
    1,1,2-trichlorotrifluoroethane 48.18
    DMS 12.19
    cumene 2.76
    2-octanol 3.85
    2-hexanone 10.54
    octyl acetate 6.43
    limonene 3.31
    1,2-dimethoxyethane 37.79
    ethyl orthosilicate 8.38
    tributyl phosphate 7.18
    diacetone alcohol 23.57
    N,N-dimethylaniline 9.22
    acrylonitrile 4.3
    aniline 4.65
    1,3-propanediol 10.26
    bromobenzene 2.91
    dibromomethane 5.88
    1,1,2,2-tetrachloroethane 21.02
    2-methyl-cyclohexyl acetate 10.41
    tetrabutyl urea 13.25
    diisobutyl methanol 2.57
    2-phenylethanol 6.41
    styrene 2.71
    dioctyl adipate 10.67
    dimethyl sulfate 32.12
    ethyl butyrate 7.14
    methyl lactate 14.93
    butyl lactate 18.63
    diethyl carbonate 5.06
    propanediol butyl ether 24.45
    triethyl orthoformate 8.91
    p-tert-butyltoluene 2.35
    methyl 4-tert-butylbenzoate 24.01
    morpholine 21.61
    tert-butylamine 3.72
    n-dodecanol 2.14
    dimethoxymethane 21.69
    ethylene carbonate 13.48
    cyrene 35.55
    2-ethoxyethyl acetate 19.06
    2-ethylhexyl acetate 6.57
    1,2,4-trichlorobenzene 8.01
    4-methylpyridine 10.63
    dibutyl ether 5.23
    2,6-dimethyl-4-heptanol 2.57
    DEF 23.67
    dimethyl isosorbide 47.91
    tetrachloroethylene 14.36
    eugenol 22.04
    triacetin 25.27
    span 80 20.69
    1,4-butanediol 6.37
    1,1-dichloroethane 4.95
    2-methyl-1-pentanol 6.97
    methyl formate 13.91
    2-methyl-1-butanol 5.89
    n-decane 0.45
    butyronitrile 3.02
    3,7-dimethyl-1-octanol 4.51
    1-chlorooctane 2.44
    1-chlorotetradecane 0.77
    n-nonane 0.4
    undecane 0.29
    tert-butylcyclohexane 0.71
    cyclooctane 0.29
    cyclopentanol 11.22
    tetrahydropyran 9.09
    tert-amyl methyl ether 8.18
    2,5,8-trioxanonane 45.06
    1-hexene 1.93
    2-isopropoxyethanol 16.94
    2,2,2-trifluoroethanol 14.34
    methyl butyrate 13.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction