L-Canavanine Sulfate

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  • Identifiers

    CAS number
    2219-31-0

    Molecular formula
    C5H14N4O7S

    SMILES
    C(CON=C(N)N)[C@@H](C(=O)O)N.OS(=O)(=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 67.27%
    Savory 35.0%
    Meaty 29.75%
    Sweet 25.12%
    Fishy 24.51%
    Cooling 20.6%
    Cooked 19.37%
    Alcoholic 16.53%
    Milky 15.62%
    Roasted 15.27%

     

    Flavor
    Odorless 60.31%
    Bitter 31.92%
    Mild 31.44%
    Bland 28.41%
    Sweet-like 22.99%
    Very mild 22.88%
    Yeast 22.05%
    Cooked 21.78%
    Faint 21.65%
    Roasted 20.93%

     

    Odor impact est.
    Odorless

  • Properties

    pKa est.
    6.41 (neutral)

    Molecular weight
    274.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    398°C

    Flash point

    • 174.5 ˚C est.

  • Synonyms

    • L-Canavanine sulfate
    • 2219-31-0
    • Canavanine sulfate
    • CANAVANINE SULPHATE
    • canavanine monosulfate
    • PN00Q697SG
    • AI3-52581
    • L-canavanine monosulfate
    • (+)-canavanine sulfate
    • EINECS 218-728-4
    • L-Homoserine, O-((aminoiminomethyl)amino)-, sulfate (1:1)
    • (+)-canavanine monosulfate
    • CANAVANINE SULFATE [MI]
    • DTXSID4044614
    • CHEBI:78901
    • O-carbamimidamido-L-homoserine sulfate
    • Butyric acid, 2-amino-4-(guanidinooxy)-, sulfate (1:1), L-
    • L-HOMOSERINE, O-((AMINOIMINOMETHYL)AMINO)-, SULFATE
    • L-Homoserine, O-[(aminoiminomethyl)amino]-, sulfate (1:1)
    • (2S)-2-azaniumyl-4-({[ammonio(imino)methyl]amino}oxy)butanoate hydrogen sulfate
    • (2S)-2-azaniumyl-4-(((ammonio(imino)methyl)amino)oxy)butanoate hydrogen sulfate
    • RefChem:795155
    • DTXCID2024614
    • L-Canavanine sulphate
    • MFCD00012618
    • (2S)-2-amino-4-(diaminomethylideneamino)oxybutanoic acid;sulfuric acid
    • (2S)-2-amino-4-{[(diaminomethylidene)amino]oxy}butanoic acid; sulfuric acid
    • C5H14N4O7S
    • UNII-PN00Q697SG
    • 2-Amino-4-(guanidinooxy)butyric Acid Sulfate
    • O-[(Aminoiminomethyl)amino]-L-homoserine Sulfate
    • L-Canavanine (sulfate)
    • (S)-2-Amino-4-(guanidinooxy)butanoic acid compound with sulfuric acid (1:1)
    • SCHEMBL344182
    • orb1301444
    • CHEMBL1551643
    • SCHEMBL29921694
    • HY-B1581A
    • MVIPJKVMOKFIEV-DFWYDOINSA-N
    • HMS3260P22
    • Tox21_500320
    • AC2526
    • CCG-36451
    • AKOS024458602
    • CS-7958
    • EBC-615853
    • FC19660
    • LP00320
    • NCGC00093764-01
    • NCGC00261005-01
    • CS-12902
    • SY128057
    • EU-0100320
    • C 9758
    • 219C310
    • F826884
    • L-Canavanine sulfate salt, >=99% (TLC), powder
    • SR-01000075795
    • SR-01000597836
    • SR-01000075795-1
    • SR-01000597836-1
    • L-alpha-Amino-gamma-(guanidinooxy)butyric acid sulfate
    • Q27148015
    • (2S)-2-amino-4-guanidinooxy-butanoic acid;sulfuric acid
    • (S)-2-Amino-4-(guanidinooxy)butanoicacidsulfuricacidsalt
    • O-(Carbamimidoylamino)-L-homoserine--sulfuric acid (1/1)
    • (S)-2-Amino-4-(guanidinooxy)butanoic acid sulfuric acid salt
    • (2S)-2-amino-4-(carbamimidamidooxy)butanoic acid; sulfuric acid
    • (2S)-2-amino-4-(diaminomethylideneamino)oxybutanoic acid sulfuric acid
    • 2219-31-0

  • Applications

    L-Canavanine Sulfate (CAS 2219-31-0) is used primarily in laboratory research as an arginine analog and antimetabolite to probe amino acid metabolism, protein synthesis, and related enzymatic pathways in biochemical and pharmaceutical studies. In plant sciences, it serves as a tool to explore legume defense mechanisms and nitrogen metabolism, including studies on plant–microbe interactions. The sulfate salt also functions as a reagent and analytical reference for amino acids and other nitrogen-containing compounds, supporting method development and validation. Additionally, it may be employed as a component in experimental media or synthetic workflows to investigate metabolic inhibition and pathway analysis; use is typically limited to research settings and subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.03
    methanol 0.14
    isopropanol 0.02
    water 37.25
    ethyl acetate 0.02
    n-propanol 0.02
    acetone 0.02
    n-butanol 0.02
    acetonitrile 0.03
    DMF 1.36
    toluene 0.04
    isobutanol 0.02
    1,4-dioxane 0.05
    methyl acetate 0.02
    THF 0.06
    2-butanone 0.03
    n-pentanol 0.02
    sec-butanol 0.02
    n-hexane 0.03
    ethylene glycol 0.71
    NMP 5.51
    cyclohexane 0.03
    DMSO 6.73
    n-butyl acetate 0.03
    n-octanol 0.02
    chloroform 0.03
    n-propyl acetate 0.02
    acetic acid 0.74
    dichloromethane 0.04
    cyclohexanone 0.15
    propylene glycol 0.38
    isopropyl acetate 0.02
    DMAc 2.55
    2-ethoxyethanol 0.2
    isopentanol 0.02
    n-heptane 0.04
    ethyl formate 0.07
    1,2-dichloroethane 0.03
    n-hexanol 0.03
    2-methoxyethanol 0.46
    isobutyl acetate 0.01
    tetrachloromethane 0.03
    n-pentyl acetate 0.02
    transcutol 0.46
    n-heptanol 0.04
    ethylbenzene 0.03
    MIBK 0.03
    2-propoxyethanol 0.23
    tert-butanol 0.04
    MTBE 0.02
    2-butoxyethanol 0.15
    propionic acid 0.14
    o-xylene 0.1
    formic acid 11.17
    diethyl ether 0.02
    m-xylene 0.06
    p-xylene 0.05
    chlorobenzene 0.02
    dimethyl carbonate 0.09
    n-octane 0.02
    formamide 4.15
    cyclopentanone 0.14
    2-pentanone 0.03
    anisole 0.03
    cyclopentyl methyl ether 0.09
    gamma-butyrolactone 0.26
    1-methoxy-2-propanol 0.27
    pyridine 0.1
    3-pentanone 0.05
    furfural 1.09
    n-dodecane 0.01
    diethylene glycol 0.91
    diisopropyl ether 0.01
    tert-amyl alcohol 0.05
    acetylacetone 0.08
    n-hexadecane 0.01
    acetophenone 0.09
    methyl propionate 0.06
    isopentyl acetate 0.03
    trichloroethylene 0.05
    n-nonanol 0.02
    cyclohexanol 0.08
    benzyl alcohol 0.07
    2-ethylhexanol 0.04
    isooctanol 0.03
    dipropyl ether 0.05
    1,2-dichlorobenzene 0.03
    ethyl lactate 0.14
    propylene carbonate 0.19
    n-methylformamide 0.52
    2-pentanol 0.02
    n-pentane 0.01
    1-propoxy-2-propanol 0.16
    1-methoxy-2-propyl acetate 0.09
    2-(2-methoxypropoxy) propanol 0.39
    mesitylene 0.06
    ε-caprolactone 0.17
    p-cymene 0.05
    epichlorohydrin 0.07
    1,1,1-trichloroethane 0.01
    2-aminoethanol 0.4
    morpholine-4-carbaldehyde 1.91
    sulfolane 2.91
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.04
    n-hexyl acetate 0.02
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 0.32
    sec-butyl acetate 0.01
    tert-butyl acetate 0.04
    decalin 0.02
    glycerin 3.7
    diglyme 0.51
    acrylic acid 0.43
    isopropyl myristate 0.01
    n-butyric acid 0.11
    acetyl acetate 0.04
    di(2-ethylhexyl) phthalate 0.07
    ethyl propionate 0.03
    nitromethane 0.49
    1,2-diethoxyethane 0.04
    benzonitrile 0.04
    trioctyl phosphate 0.04
    1-bromopropane 0.01
    gamma-valerolactone 0.63
    n-decanol 0.02
    triethyl phosphate 0.1
    4-methyl-2-pentanol 0.02
    propionitrile 0.02
    vinylene carbonate 0.22
    1,1,2-trichlorotrifluoroethane 1.26
    DMS 0.06
    cumene 0.04
    2-octanol 0.02
    2-hexanone 0.02
    octyl acetate 0.02
    limonene 0.06
    1,2-dimethoxyethane 0.21
    ethyl orthosilicate 0.09
    tributyl phosphate 0.06
    diacetone alcohol 0.18
    N,N-dimethylaniline 0.11
    acrylonitrile 0.05
    aniline 0.08
    1,3-propanediol 0.22
    bromobenzene 0.02
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.07
    2-methyl-cyclohexyl acetate 0.06
    tetrabutyl urea 0.12
    diisobutyl methanol 0.04
    2-phenylethanol 0.06
    styrene 0.03
    dioctyl adipate 0.03
    dimethyl sulfate 0.61
    ethyl butyrate 0.04
    methyl lactate 0.4
    butyl lactate 0.13
    diethyl carbonate 0.03
    propanediol butyl ether 0.27
    triethyl orthoformate 0.08
    p-tert-butyltoluene 0.05
    methyl 4-tert-butylbenzoate 0.23
    morpholine 0.09
    tert-butylamine 0.02
    n-dodecanol 0.02
    dimethoxymethane 0.17
    ethylene carbonate 0.11
    cyrene 1.07
    2-ethoxyethyl acetate 0.04
    2-ethylhexyl acetate 0.03
    1,2,4-trichlorobenzene 0.04
    4-methylpyridine 0.09
    dibutyl ether 0.02
    2,6-dimethyl-4-heptanol 0.04
    DEF 0.21
    dimethyl isosorbide 0.7
    tetrachloroethylene 0.09
    eugenol 0.31
    triacetin 0.09
    span 80 0.31
    1,4-butanediol 0.12
    1,1-dichloroethane 0.01
    2-methyl-1-pentanol 0.02
    methyl formate 0.32
    2-methyl-1-butanol 0.03
    n-decane 0.01
    butyronitrile 0.02
    3,7-dimethyl-1-octanol 0.02
    1-chlorooctane 0.01
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.01
    cyclooctane 0.02
    cyclopentanol 0.07
    tetrahydropyran 0.03
    tert-amyl methyl ether 0.04
    2,5,8-trioxanonane 0.65
    1-hexene 0.03
    2-isopropoxyethanol 0.09
    2,2,2-trifluoroethanol 0.98
    methyl butyrate 0.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction