(-)-Kanzonol F

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  • Identifiers

    CAS number
    152511-44-9

    Molecular formula
    C26H28O5

    SMILES
    CC(=CCC1=C(C2=C(C=C1O)OCC3C2OC4=C3C=C5C=CC(OC5=C4)(C)C)OC)C

    Safety labels

  • Odor profile

    Fragrance
    Spicy 48.47%
    Sweet 36.83%
    Phenolic 32.18%
    Woody 27.22%
    Herbal 23.3%
    Powdery 23.25%
    Balsamic 23.25%
    Floral 22.52%
    Fruity 22.27%
    Warm 21.36%

     

    Flavor
    Bitter 87.21%
    Cedarleaf 19.96%
    Parsley 19.79%
    Lovage 18.92%
    Bland 18.33%
    Ripe apricot 18.15%
    Red fruit 17.83%
    Carrot 17.44%
    Eugenol 17.43%
    Sweet-like 17.35%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.5

    pKa est.
    7.76 (neutral)

    Molecular weight
    420.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1104°C

    Flash point

    • 220.0 ˚C est.

  • Synonyms

    • (-)-Kanzonol F
    • 152511-44-9
    • 15-methoxy-7,7-dimethyl-16-(3-methylbut-2-enyl)-8,12,20-trioxapentacyclo(11.8.0.02,11.04,9.014,19)henicosa-2(11),3,5,9,14(19),15,17-heptaen-17-ol
    • 15-methoxy-7,7-dimethyl-16-(3-methylbut-2-enyl)-8,12,20-trioxapentacyclo[11.8.0.02,11.04,9.014,19]henicosa-2(11),3,5,9,14(19),15,17-heptaen-17-ol
    • RefChem:67869
    • DTXSID401319078
    • 1-Methoxy-10,10-dimethyl-2-(3-methylbut-2-en-1-yl)-6a,13a-dihydro-6H,10H-pyrano[3',2':5,6][1]benzofuro[3,2-c][1]benzopyran-3-ol
    • 152511-44-9

  • Applications

    (-)-Kanzonol F (CAS 152511-44-9) is primarily explored as a chiral building block and intermediate in organic synthesis, with potential applications across pharmaceutical and fine chemicals manufacturing. In fragrance and cosmetics research, it may be evaluated as a fragrance-active constituent or aroma precursor, contributing to stereochemically defined scent profiles. The compound is also of interest in agrochemical research as a potential synthetic intermediate for the development of target molecules. In addition, it may find use in industrial manufacturing as a chiral auxiliary or reference material for asymmetric synthesis and process development. Subject to local regulations and formulation limits, its practical use depends on specific routes and purity.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.77
    methanol 5.82
    isopropanol 5.19
    water 0.02
    ethyl acetate 43.5
    n-propanol 7.03
    acetone 44.68
    n-butanol 7.5
    acetonitrile 16.97
    DMF 49.46
    toluene 20.2
    isobutanol 6.67
    1,4-dioxane 66.09
    methyl acetate 41.14
    THF 96.13
    2-butanone 46.74
    n-pentanol 7.49
    sec-butanol 4.36
    n-hexane 0.34
    ethylene glycol 2.62
    NMP 91.92
    cyclohexane 1.08
    DMSO 58.39
    n-butyl acetate 35.54
    n-octanol 10.28
    chloroform 242.65
    n-propyl acetate 32.54
    acetic acid 43.16
    dichloromethane 163.3
    cyclohexanone 82.39
    propylene glycol 2.99
    isopropyl acetate 31.32
    DMAc 132.05
    2-ethoxyethanol 26.08
    isopentanol 9.71
    n-heptane 0.58
    ethyl formate 26.58
    1,2-dichloroethane 80.89
    n-hexanol 9.44
    2-methoxyethanol 32.17
    isobutyl acetate 30.99
    tetrachloromethane 14.31
    n-pentyl acetate 32.64
    transcutol 119.24
    n-heptanol 9.49
    ethylbenzene 8.05
    MIBK 28.52
    2-propoxyethanol 53.23
    tert-butanol 7.67
    MTBE 10.25
    2-butoxyethanol 36.61
    propionic acid 19.28
    o-xylene 10.14
    formic acid 12.03
    diethyl ether 11.81
    m-xylene 11.9
    p-xylene 13.67
    chlorobenzene 44.65
    dimethyl carbonate 43.54
    n-octane 0.37
    formamide 15.6
    cyclopentanone 97.6
    2-pentanone 35.34
    anisole 26.3
    cyclopentyl methyl ether 30.21
    gamma-butyrolactone 109.42
    1-methoxy-2-propanol 26.38
    pyridine 74.33
    3-pentanone 35.77
    furfural 96.27
    n-dodecane 0.68
    diethylene glycol 35.44
    diisopropyl ether 5.06
    tert-amyl alcohol 6.02
    acetylacetone 66.39
    n-hexadecane 0.86
    acetophenone 41.04
    methyl propionate 42.86
    isopentyl acetate 40.07
    trichloroethylene 235.81
    n-nonanol 11.7
    cyclohexanol 11.06
    benzyl alcohol 23.92
    2-ethylhexanol 9.57
    isooctanol 9.66
    dipropyl ether 12.17
    1,2-dichlorobenzene 50.83
    ethyl lactate 21.73
    propylene carbonate 58.48
    n-methylformamide 22.0
    2-pentanol 4.44
    n-pentane 0.34
    1-propoxy-2-propanol 35.15
    1-methoxy-2-propyl acetate 62.68
    2-(2-methoxypropoxy) propanol 47.36
    mesitylene 6.33
    ε-caprolactone 68.9
    p-cymene 8.59
    epichlorohydrin 141.33
    1,1,1-trichloroethane 72.81
    2-aminoethanol 4.64
    morpholine-4-carbaldehyde 106.35
    sulfolane 112.02
    2,2,4-trimethylpentane 0.49
    2-methyltetrahydrofuran 40.95
    n-hexyl acetate 39.71
    isooctane 0.4
    2-(2-butoxyethoxy)ethanol 57.23
    sec-butyl acetate 25.17
    tert-butyl acetate 31.46
    decalin 1.13
    glycerin 10.58
    diglyme 104.82
    acrylic acid 23.58
    isopropyl myristate 20.29
    n-butyric acid 33.96
    acetyl acetate 54.08
    di(2-ethylhexyl) phthalate 25.52
    ethyl propionate 31.25
    nitromethane 92.41
    1,2-diethoxyethane 41.07
    benzonitrile 36.61
    trioctyl phosphate 17.7
    1-bromopropane 22.47
    gamma-valerolactone 157.21
    n-decanol 8.49
    triethyl phosphate 24.79
    4-methyl-2-pentanol 5.82
    propionitrile 20.43
    vinylene carbonate 74.16
    1,1,2-trichlorotrifluoroethane 113.07
    DMS 50.71
    cumene 6.69
    2-octanol 5.78
    2-hexanone 31.33
    octyl acetate 24.8
    limonene 9.24
    1,2-dimethoxyethane 55.32
    ethyl orthosilicate 21.96
    tributyl phosphate 21.55
    diacetone alcohol 34.36
    N,N-dimethylaniline 18.22
    acrylonitrile 30.79
    aniline 23.89
    1,3-propanediol 10.88
    bromobenzene 52.37
    dibromomethane 84.33
    1,1,2,2-tetrachloroethane 165.79
    2-methyl-cyclohexyl acetate 36.37
    tetrabutyl urea 29.76
    diisobutyl methanol 6.99
    2-phenylethanol 32.1
    styrene 10.81
    dioctyl adipate 34.6
    dimethyl sulfate 66.45
    ethyl butyrate 29.47
    methyl lactate 27.46
    butyl lactate 29.23
    diethyl carbonate 26.28
    propanediol butyl ether 26.15
    triethyl orthoformate 29.18
    p-tert-butyltoluene 7.3
    methyl 4-tert-butylbenzoate 41.5
    morpholine 58.09
    tert-butylamine 3.69
    n-dodecanol 6.42
    dimethoxymethane 56.67
    ethylene carbonate 61.43
    cyrene 52.41
    2-ethoxyethyl acetate 59.94
    2-ethylhexyl acetate 32.66
    1,2,4-trichlorobenzene 68.89
    4-methylpyridine 57.39
    dibutyl ether 13.85
    2,6-dimethyl-4-heptanol 6.99
    DEF 41.65
    dimethyl isosorbide 85.87
    tetrachloroethylene 87.34
    eugenol 40.31
    triacetin 58.44
    span 80 33.67
    1,4-butanediol 5.27
    1,1-dichloroethane 61.5
    2-methyl-1-pentanol 9.42
    methyl formate 26.08
    2-methyl-1-butanol 7.64
    n-decane 1.03
    butyronitrile 17.3
    3,7-dimethyl-1-octanol 12.25
    1-chlorooctane 6.86
    1-chlorotetradecane 3.57
    n-nonane 0.74
    undecane 0.81
    tert-butylcyclohexane 0.89
    cyclooctane 0.47
    cyclopentanol 12.78
    tetrahydropyran 37.46
    tert-amyl methyl ether 9.11
    2,5,8-trioxanonane 83.18
    1-hexene 2.08
    2-isopropoxyethanol 24.13
    2,2,2-trifluoroethanol 20.28
    methyl butyrate 36.49

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction