kaempferol 7-O-glucoside

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  • Identifiers

    CAS number
    16290-07-6

    Molecular formula
    C21H20O11

    SMILES
    C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O

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  • Odor profile

    Fragrance
    Odorless 75.63%
    Phenolic 34.43%
    Vanilla 28.17%
    Burnt 22.97%
    Savory 21.57%
    Bitter 20.93%
    Milky 20.63%
    Smoky 19.62%
    Sweet 19.11%
    Creamy 17.86%

     

    Flavor
    Bitter 83.0%
    Odorless 34.86%
    Bland 31.43%
    Sweet-like 26.09%
    Cedarleaf 20.24%
    Very mild 19.75%
    Parsley 19.57%
    Eugenol 19.51%
    Lovage 19.43%
    Nitrile 19.07%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.7

    pKa est.
    8.88 (weak base)

    Molecular weight
    448.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    3873°C

    Flash point

    • 312.0 ˚C est.

  • Synonyms

    • 16290-07-6
    • kaempferol 7-O-glucoside
    • Kaempferol-7-o-beta-D-glucopyranoside
    • Kaempferol-7-o-D-glucopyranoside
    • RZF1QN1Z8R
    • RefChem:40118
    • Kaempferol-7-O-|A-D-glucopyranoside
    • Kaempferol 7-o-beta-D-glucopyranoside
    • KAEMPFEROL-7-GLUCOPYRANOSIDE
    • MFCD08459623
    • kaempferol-7-o-beta-d-glucoside
    • Populnin
    • 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3,5-dihydroxy-2-(4-hydroxyphenyl)-
    • 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
    • 3,5-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
    • 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
    • Kaempferol-7-glucoside; Kaempferol-7-O-beta-D-glucopyranoside
    • Kaempferol 7-glucoside
    • UNII-RZF1QN1Z8R
    • kaempferol 7-O-beta-glucoside
    • Kaempferol 7-O-|A -D-glucopyranoside
    • kaempferol 7-O-glycoside
    • kaempferol-7-O-glucopyranoside
    • CHEMBL469441
    • orb1303193
    • SCHEMBL3462759
    • SCHEMBL29480897
    • CHEBI:75790
    • BDBM226180
    • DTXSID301029781
    • Kaempferol-7-O--D-glucopyranoside
    • HY-N0627
    • AKOS016004615
    • EBC-617645
    • Kaempferol 7-O-beta-D-glucoside (4)
    • Kaempferol 7-O-beta -D-glucopyranoside
    • 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one
    • AC-34756
    • DA-54588
    • MS-28115
    • XK171016
    • CS-0009619
    • KAEMPFEROL 7-O-.BETA.-D-GLUCOPYRANOSIDE
    • KAEMPFEROL-7-O-.BETA.-D-GLUCOPYRANOSIDE
    • Q3266683
    • Kaempferol 7-O-beta -D-glucopyranoside, >=90.0% (HPLC)
    • KAEMPFEROL 7-O-GLUCOSIDE (CONSTITUENT OF GINKGO) [DSC]
    • 4H-1-Benzopyran-4-one, 7-(|A-D-glucopyranosyloxy)-3,5-dihydroxy-2-(4-hydroxyphenyl)-
    • 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one
    • 7-(ss-D-Glucopyranosyloxy)-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one; Kaempferol 7-ss-D-glucopyranoside
    • 16290-07-6

  • Applications

    kaempferol 7-O-glucoside (CAS 16290-07-6) has practical applications across several sectors: used as an antioxidant additive in cosmetics and personal care; evaluated as a natural antioxidant in food processing and shelf-life stabilization; employed as a reference standard for HPLC/LC-MS analysis and research on plant flavonoids; functions as an antioxidant stabilizer in coatings, paints, inks, and polymer formulations; and is studied in agriculture and plant sciences as a representative flavonol glycoside for metabolomics and phytochemical investigations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.22
    methanol 2.84
    isopropanol 0.5
    water 0.04
    ethyl acetate 0.03
    n-propanol 1.45
    acetone 0.77
    n-butanol 0.39
    acetonitrile 0.04
    DMF 11.08
    toluene 0.01
    isobutanol 0.29
    1,4-dioxane 0.9
    methyl acetate 0.11
    THF 2.14
    2-butanone 0.56
    n-pentanol 0.2
    sec-butanol 0.55
    n-hexane 0.0
    ethylene glycol 9.45
    NMP 9.74
    cyclohexane 0.0
    DMSO 43.43
    n-butyl acetate 0.03
    n-octanol 0.21
    chloroform 0.0
    n-propyl acetate 0.03
    acetic acid 2.6
    dichloromethane 0.0
    cyclohexanone 0.52
    propylene glycol 9.7
    isopropyl acetate 0.02
    DMAc 11.52
    2-ethoxyethanol 6.78
    isopentanol 0.16
    n-heptane 0.01
    ethyl formate 0.11
    1,2-dichloroethane 0.01
    n-hexanol 0.1
    2-methoxyethanol 26.93
    isobutyl acetate 0.01
    tetrachloromethane 0.0
    n-pentyl acetate 0.08
    transcutol 7.38
    n-heptanol 0.22
    ethylbenzene 0.01
    MIBK 0.05
    2-propoxyethanol 2.88
    tert-butanol 0.23
    MTBE 0.05
    2-butoxyethanol 2.35
    propionic acid 0.76
    o-xylene 0.01
    formic acid 10.86
    diethyl ether 0.07
    m-xylene 0.01
    p-xylene 0.01
    chlorobenzene 0.0
    dimethyl carbonate 0.15
    n-octane 0.0
    formamide 11.22
    cyclopentanone 1.4
    2-pentanone 0.17
    anisole 0.03
    cyclopentyl methyl ether 0.16
    gamma-butyrolactone 1.19
    1-methoxy-2-propanol 8.95
    pyridine 0.28
    3-pentanone 0.11
    furfural 1.11
    n-dodecane 0.0
    diethylene glycol 6.83
    diisopropyl ether 0.01
    tert-amyl alcohol 0.27
    acetylacetone 0.22
    n-hexadecane 0.0
    acetophenone 0.05
    methyl propionate 0.14
    isopentyl acetate 0.03
    trichloroethylene 0.01
    n-nonanol 0.23
    cyclohexanol 0.21
    benzyl alcohol 0.11
    2-ethylhexanol 0.04
    isooctanol 0.11
    dipropyl ether 0.07
    1,2-dichlorobenzene 0.0
    ethyl lactate 0.28
    propylene carbonate 0.12
    n-methylformamide 4.34
    2-pentanol 0.12
    n-pentane 0.0
    1-propoxy-2-propanol 1.25
    1-methoxy-2-propyl acetate 0.2
    2-(2-methoxypropoxy) propanol 1.88
    mesitylene 0.0
    ε-caprolactone 0.44
    p-cymene 0.01
    epichlorohydrin 0.56
    1,1,1-trichloroethane 0.0
    2-aminoethanol 12.24
    morpholine-4-carbaldehyde 9.95
    sulfolane 5.98
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.37
    n-hexyl acetate 0.12
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 3.57
    sec-butyl acetate 0.02
    tert-butyl acetate 0.04
    decalin 0.0
    glycerin 28.02
    diglyme 5.12
    acrylic acid 1.21
    isopropyl myristate 0.04
    n-butyric acid 0.29
    acetyl acetate 0.02
    di(2-ethylhexyl) phthalate 0.1
    ethyl propionate 0.03
    nitromethane 2.04
    1,2-diethoxyethane 0.24
    benzonitrile 0.02
    trioctyl phosphate 0.09
    1-bromopropane 0.01
    gamma-valerolactone 7.6
    n-decanol 0.14
    triethyl phosphate 0.04
    4-methyl-2-pentanol 0.04
    propionitrile 0.05
    vinylene carbonate 0.1
    1,1,2-trichlorotrifluoroethane 2.54
    DMS 0.08
    cumene 0.0
    2-octanol 0.11
    2-hexanone 0.09
    octyl acetate 0.09
    limonene 0.01
    1,2-dimethoxyethane 2.59
    ethyl orthosilicate 0.04
    tributyl phosphate 0.06
    diacetone alcohol 0.67
    N,N-dimethylaniline 0.03
    acrylonitrile 0.12
    aniline 0.06
    1,3-propanediol 7.8
    bromobenzene 0.0
    dibromomethane 0.0
    1,1,2,2-tetrachloroethane 0.01
    2-methyl-cyclohexyl acetate 0.04
    tetrabutyl urea 0.21
    diisobutyl methanol 0.02
    2-phenylethanol 0.07
    styrene 0.0
    dioctyl adipate 0.11
    dimethyl sulfate 0.51
    ethyl butyrate 0.04
    methyl lactate 1.41
    butyl lactate 0.39
    diethyl carbonate 0.02
    propanediol butyl ether 3.31
    triethyl orthoformate 0.07
    p-tert-butyltoluene 0.01
    methyl 4-tert-butylbenzoate 0.29
    morpholine 3.13
    tert-butylamine 0.04
    n-dodecanol 0.07
    dimethoxymethane 2.38
    ethylene carbonate 0.07
    cyrene 2.22
    2-ethoxyethyl acetate 0.23
    2-ethylhexyl acetate 0.02
    1,2,4-trichlorobenzene 0.0
    4-methylpyridine 0.08
    dibutyl ether 0.07
    2,6-dimethyl-4-heptanol 0.02
    DEF 0.43
    dimethyl isosorbide 1.44
    tetrachloroethylene 0.01
    eugenol 0.51
    triacetin 0.26
    span 80 1.47
    1,4-butanediol 1.75
    1,1-dichloroethane 0.0
    2-methyl-1-pentanol 0.1
    methyl formate 1.53
    2-methyl-1-butanol 0.23
    n-decane 0.01
    butyronitrile 0.03
    3,7-dimethyl-1-octanol 0.07
    1-chlorooctane 0.02
    1-chlorotetradecane 0.01
    n-nonane 0.0
    undecane 0.0
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.57
    tetrahydropyran 0.3
    tert-amyl methyl ether 0.07
    2,5,8-trioxanonane 3.68
    1-hexene 0.01
    2-isopropoxyethanol 1.28
    2,2,2-trifluoroethanol 0.64
    methyl butyrate 0.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction