Jwh-073

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  • Identifiers

    CAS number
    208987-48-8

    Molecular formula
    C23H21NO

    SMILES
    CCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Floral 54.66%
    Grape 44.65%
    Neroli 44.37%
    Fruity 38.43%
    Animal 37.27%
    Orange 33.76%
    Sweet 28.47%
    Balsamic 25.22%
    Honey 25.07%
    Rose 23.56%

     

    Flavor
    Bitter 79.43%
    Nitrile 20.06%
    Very strong 19.8%
    Indole 19.57%
    Lovage 19.53%
    Cedarleaf 19.16%
    Animal 19.14%
    Heather 18.72%
    Moth ball 18.6%
    Odorless 18.57%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.8

    pKa est.
    6.54 (neutral)

    Molecular weight
    327.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    609°C

    Flash point

    • 245.27 ˚C est.

  • Synonyms

    • 208987-48-8
    • 1-Butyl-3-(1-naphthoyl)indole
    • JWH 073
    • JWH-073
    • JWH073
    • 1-Butyl-3-(1-naphthoyl) indole
    • DEA No.7173
    • BBX3BP2772
    • (1-Butyl-1h-Indol-3-Yl)(Naphthalen-1-Yl)Methanone
    • (1-butylindol-3-yl)-naphthalen-1-ylmethanone
    • HSDB 7999
    • Methanone, (1-butyl-1H-indol-3-yl)-1-naphthalenyl-
    • UNII-BBX3BP2772
    • CTDP-32476 HCl
    • DTXSID20175042
    • (1-butyl-1H-indole-3-yl)-1-naphthalenyl methanone
    • 1-Butyl-3-(1-naphthoyl)indoleJWH-073
    • J2.856.750B
    • naphthalen-1-yl-(1-butylindol-3-yl)methanone
    • 1-naphthalenyl(1-butyl-1h-indol-3-yl)methanone
    • (1-BUTYL-1H-INDOLE-3-YL)(NAPHTHALENE-1-YL)METHANONE
    • JWH 073-d7
    • 1-Butyl-3-(1-naphthoyl)indoleJWH-073 (100ug/mL in Acetonitrile)
    • C23H21NO
    • CHEMBL2380416
    • DTXCID5097533
    • SCHEMBL11983320
    • BDBM85804
    • JWH-073, 1mg/ml in Methanol
    • CHEBI:181123
    • VCHHHSMPMLNVGS-UHFFFAOYSA-N
    • JWH-073; JWH073
    • BCP24000
    • QGC74443
    • WDC60194
    • JWH-073, 0.1mg/ml in Methanol
    • PDSP1_000254
    • PDSP2_000253
    • 1-Butyl-3-(1-naphthoyl)-1H-indole
    • AKOS005146537
    • CCG-208716
    • CS-0827
    • NCGC00378993-02
    • HY-32733
    • A4544
    • NS00009066
    • 1-Naphthyl(1-butyl-1H-indole-3-yl)methanone
    • Naphthaten-1-yl-(1-butylindol-3-yl)methanone
    • 10.14272/VCHHHSMPMLNVGS-UHFFFAOYSA-N.1
    • Q423476
    • doi:10.14272/VCHHHSMPMLNVGS-UHFFFAOYSA-N.1
    • (1-butyl-1H-indol-3-yl)(naphthalen-1-yl)methanone;JWH-073

  • Applications

    Jwh-073, CAS 208987-48-8, is a synthetic cannabinoid primarily used in research settings to study CB1/CB2 receptor interactions and structure-activity relationships. In analytical chemistry and forensic toxicology, it serves as a reference standard and analyte for method development and screening of synthetic cannabinoids. It functions as a research ligand in academic and industrial laboratories to support SAR studies and cannabinoid chemistry investigations. It is often used as an educational reagent in teaching and training environments for analytical method validation and cannabinoid profiling. Use outside controlled research contexts is limited and subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 34.61
    methanol 33.93
    isopropanol 14.53
    water 0.02
    ethyl acetate 95.64
    n-propanol 40.64
    acetone 133.95
    n-butanol 40.07
    acetonitrile 35.31
    DMF 347.6
    toluene 133.23
    isobutanol 33.63
    1,4-dioxane 204.51
    methyl acetate 125.72
    THF 364.02
    2-butanone 164.52
    n-pentanol 34.09
    sec-butanol 25.48
    n-hexane 2.76
    ethylene glycol 5.3
    NMP 288.47
    cyclohexane 6.59
    DMSO 78.99
    n-butyl acetate 80.68
    n-octanol 11.72
    chloroform 741.7
    n-propyl acetate 80.38
    acetic acid 56.39
    dichloromethane 996.75
    cyclohexanone 270.71
    propylene glycol 7.36
    isopropyl acetate 70.81
    DMAc 343.4
    2-ethoxyethanol 63.64
    isopentanol 43.78
    n-heptane 2.01
    ethyl formate 59.73
    1,2-dichloroethane 607.72
    n-hexanol 31.87
    2-methoxyethanol 89.81
    isobutyl acetate 72.45
    tetrachloromethane 29.99
    n-pentyl acetate 67.86
    transcutol 253.05
    n-heptanol 18.71
    ethylbenzene 54.57
    MIBK 79.17
    2-propoxyethanol 85.5
    tert-butanol 15.78
    MTBE 41.9
    2-butoxyethanol 56.81
    propionic acid 47.97
    o-xylene 45.82
    formic acid 17.88
    diethyl ether 78.99
    m-xylene 50.6
    p-xylene 66.3
    chlorobenzene 220.44
    dimethyl carbonate 90.18
    n-octane 1.53
    formamide 45.61
    cyclopentanone 337.0
    2-pentanone 116.53
    anisole 118.38
    cyclopentyl methyl ether 123.47
    gamma-butyrolactone 294.84
    1-methoxy-2-propanol 58.66
    pyridine 395.96
    3-pentanone 120.81
    furfural 280.96
    n-dodecane 1.47
    diethylene glycol 46.52
    diisopropyl ether 17.9
    tert-amyl alcohol 23.15
    acetylacetone 169.4
    n-hexadecane 1.76
    acetophenone 112.24
    methyl propionate 114.71
    isopentyl acetate 89.6
    trichloroethylene 1143.08
    n-nonanol 13.59
    cyclohexanol 46.06
    benzyl alcohol 92.56
    2-ethylhexanol 25.57
    isooctanol 19.38
    dipropyl ether 35.75
    1,2-dichlorobenzene 191.99
    ethyl lactate 32.88
    propylene carbonate 142.8
    n-methylformamide 86.97
    2-pentanol 21.89
    n-pentane 2.22
    1-propoxy-2-propanol 46.07
    1-methoxy-2-propyl acetate 96.53
    2-(2-methoxypropoxy) propanol 58.67
    mesitylene 21.12
    ε-caprolactone 204.54
    p-cymene 21.11
    epichlorohydrin 659.47
    1,1,1-trichloroethane 223.12
    2-aminoethanol 17.15
    morpholine-4-carbaldehyde 253.76
    sulfolane 234.92
    2,2,4-trimethylpentane 2.49
    2-methyltetrahydrofuran 187.94
    n-hexyl acetate 63.57
    isooctane 1.38
    2-(2-butoxyethoxy)ethanol 76.19
    sec-butyl acetate 63.93
    tert-butyl acetate 63.84
    decalin 5.5
    glycerin 14.81
    diglyme 186.23
    acrylic acid 57.78
    isopropyl myristate 25.84
    n-butyric acid 73.78
    acetyl acetate 71.43
    di(2-ethylhexyl) phthalate 36.0
    ethyl propionate 73.94
    nitromethane 150.14
    1,2-diethoxyethane 105.44
    benzonitrile 110.78
    trioctyl phosphate 18.57
    1-bromopropane 190.97
    gamma-valerolactone 408.57
    n-decanol 10.36
    triethyl phosphate 34.7
    4-methyl-2-pentanol 18.75
    propionitrile 58.07
    vinylene carbonate 159.38
    1,1,2-trichlorotrifluoroethane 208.84
    DMS 109.67
    cumene 29.66
    2-octanol 12.73
    2-hexanone 94.18
    octyl acetate 31.93
    limonene 26.65
    1,2-dimethoxyethane 170.17
    ethyl orthosilicate 35.02
    tributyl phosphate 25.51
    diacetone alcohol 63.51
    N,N-dimethylaniline 59.44
    acrylonitrile 96.98
    aniline 124.8
    1,3-propanediol 30.65
    bromobenzene 246.41
    dibromomethane 480.4
    1,1,2,2-tetrachloroethane 650.22
    2-methyl-cyclohexyl acetate 63.65
    tetrabutyl urea 38.62
    diisobutyl methanol 15.25
    2-phenylethanol 76.85
    styrene 79.72
    dioctyl adipate 46.86
    dimethyl sulfate 114.12
    ethyl butyrate 61.04
    methyl lactate 41.48
    butyl lactate 44.64
    diethyl carbonate 44.86
    propanediol butyl ether 31.4
    triethyl orthoformate 45.19
    p-tert-butyltoluene 16.49
    methyl 4-tert-butylbenzoate 67.48
    morpholine 228.29
    tert-butylamine 10.83
    n-dodecanol 8.43
    dimethoxymethane 192.27
    ethylene carbonate 116.4
    cyrene 73.31
    2-ethoxyethyl acetate 127.26
    2-ethylhexyl acetate 73.33
    1,2,4-trichlorobenzene 232.35
    4-methylpyridine 284.78
    dibutyl ether 31.35
    2,6-dimethyl-4-heptanol 15.25
    DEF 167.38
    dimethyl isosorbide 124.55
    tetrachloroethylene 398.54
    eugenol 71.92
    triacetin 68.66
    span 80 43.76
    1,4-butanediol 12.56
    1,1-dichloroethane 277.79
    2-methyl-1-pentanol 46.46
    methyl formate 76.02
    2-methyl-1-butanol 48.01
    n-decane 2.29
    butyronitrile 57.11
    3,7-dimethyl-1-octanol 17.18
    1-chlorooctane 15.05
    1-chlorotetradecane 6.88
    n-nonane 1.88
    undecane 1.76
    tert-butylcyclohexane 4.12
    cyclooctane 1.68
    cyclopentanol 46.37
    tetrahydropyran 194.06
    tert-amyl methyl ether 41.3
    2,5,8-trioxanonane 116.42
    1-hexene 25.47
    2-isopropoxyethanol 51.74
    2,2,2-trifluoroethanol 25.3
    methyl butyrate 99.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction