Isostearyl Sebacate

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  • Identifiers

    CAS number
    478273-24-4

    Molecular formula
    C28H54O4

    SMILES
    CC(C)CCCCCCCCCCCCCCCOC(=O)CCCCCCCCC(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 68.86%
    Fatty 57.61%
    Oily 40.58%
    Odorless 37.88%
    Creamy 24.22%
    Milky 21.17%
    Sweet 20.81%
    Woody 19.42%
    Soapy 18.86%
    Alcoholic 18.52%

     

    Flavor
    Fatty 55.8%
    Waxy 53.97%
    Oily 44.68%
    Mild 42.5%
    Bland 34.18%
    Fat 33.72%
    Faint 33.1%
    Coconut 31.86%
    Soapy 31.6%
    Creamy 29.28%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    11.0

    pKa est.
    7.5 (neutral)

    Molecular weight
    454.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    516°C

    Flash point

    • 238.74 ˚C est.

  • Synonyms

    • isostearyl sebacate
    • S78O3FPG9R
    • UNII-S78O3FPG9R
    • Isostearyl sebacate [INCI]
    • 478273-24-4
    • RefChem:149999
    • SCHEMBL246684
    • Q27288766
    • 478273-24-4

  • Applications

    Isostearyl Sebacate (CAS 478273-24-4) is widely used as an emollient and solvent in cosmetic and personal care formulations. It also serves as a solvent/diluent for fragrance oils in perfumery, acts as a plasticizer for polymer systems, and functions as a processing aid or diluent in coatings and inks. In household products, it can act as a carrier and solvent for active ingredients or fragrances, helping improve texture and spreadability. These applications may vary with local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.63
    methanol 3.89
    isopropanol 2.34
    water 0.02
    ethyl acetate 15.42
    n-propanol 3.61
    acetone 11.78
    n-butanol 4.09
    acetonitrile 3.39
    DMF 29.32
    toluene 9.8
    isobutanol 3.57
    1,4-dioxane 23.22
    methyl acetate 11.77
    THF 94.9
    2-butanone 18.76
    n-pentanol 5.44
    sec-butanol 4.64
    n-hexane 2.16
    ethylene glycol 0.42
    NMP 148.23
    cyclohexane 6.77
    DMSO 45.2
    n-butyl acetate 25.63
    n-octanol 10.94
    chloroform 85.28
    n-propyl acetate 27.58
    acetic acid 9.84
    dichloromethane 84.5
    cyclohexanone 79.65
    propylene glycol 1.35
    isopropyl acetate 19.77
    DMAc 99.54
    2-ethoxyethanol 15.94
    isopentanol 6.5
    n-heptane 2.0
    ethyl formate 9.55
    1,2-dichloroethane 47.02
    n-hexanol 5.24
    2-methoxyethanol 12.88
    isobutyl acetate 21.81
    tetrachloromethane 16.68
    n-pentyl acetate 54.7
    transcutol 149.42
    n-heptanol 9.17
    ethylbenzene 10.51
    MIBK 23.65
    2-propoxyethanol 18.82
    tert-butanol 6.62
    MTBE 13.78
    2-butoxyethanol 30.81
    propionic acid 8.35
    o-xylene 12.22
    formic acid 3.01
    diethyl ether 7.25
    m-xylene 9.48
    p-xylene 14.57
    chlorobenzene 20.42
    dimethyl carbonate 7.68
    n-octane 1.45
    formamide 5.62
    cyclopentanone 87.3
    2-pentanone 18.92
    anisole 20.62
    cyclopentyl methyl ether 40.94
    gamma-butyrolactone 81.83
    1-methoxy-2-propanol 16.46
    pyridine 29.83
    3-pentanone 19.31
    furfural 62.72
    n-dodecane 0.96
    diethylene glycol 7.46
    diisopropyl ether 6.14
    tert-amyl alcohol 10.96
    acetylacetone 34.46
    n-hexadecane 1.15
    acetophenone 36.13
    methyl propionate 14.83
    isopentyl acetate 32.16
    trichloroethylene 99.55
    n-nonanol 12.25
    cyclohexanol 13.21
    benzyl alcohol 12.65
    2-ethylhexanol 8.15
    isooctanol 11.15
    dipropyl ether 15.33
    1,2-dichlorobenzene 33.42
    ethyl lactate 16.03
    propylene carbonate 51.1
    n-methylformamide 8.77
    2-pentanol 4.18
    n-pentane 1.04
    1-propoxy-2-propanol 22.94
    1-methoxy-2-propyl acetate 39.16
    2-(2-methoxypropoxy) propanol 46.63
    mesitylene 8.54
    ε-caprolactone 79.02
    p-cymene 10.04
    epichlorohydrin 78.7
    1,1,1-trichloroethane 53.38
    2-aminoethanol 1.7
    morpholine-4-carbaldehyde 68.54
    sulfolane 198.52
    2,2,4-trimethylpentane 2.53
    2-methyltetrahydrofuran 54.13
    n-hexyl acetate 52.22
    isooctane 1.21
    2-(2-butoxyethoxy)ethanol 52.17
    sec-butyl acetate 25.97
    tert-butyl acetate 41.25
    decalin 5.17
    glycerin 3.5
    diglyme 118.2
    acrylic acid 6.69
    isopropyl myristate 17.61
    n-butyric acid 19.04
    acetyl acetate 15.2
    di(2-ethylhexyl) phthalate 18.28
    ethyl propionate 25.41
    nitromethane 23.14
    1,2-diethoxyethane 42.51
    benzonitrile 14.92
    trioctyl phosphate 12.09
    1-bromopropane 21.33
    gamma-valerolactone 120.57
    n-decanol 7.4
    triethyl phosphate 26.76
    4-methyl-2-pentanol 5.34
    propionitrile 4.99
    vinylene carbonate 36.28
    1,1,2-trichlorotrifluoroethane 64.11
    DMS 25.44
    cumene 9.26
    2-octanol 9.28
    2-hexanone 27.84
    octyl acetate 20.55
    limonene 16.1
    1,2-dimethoxyethane 44.73
    ethyl orthosilicate 27.24
    tributyl phosphate 17.34
    diacetone alcohol 41.03
    N,N-dimethylaniline 20.41
    acrylonitrile 5.8
    aniline 9.55
    1,3-propanediol 3.57
    bromobenzene 25.67
    dibromomethane 48.62
    1,1,2,2-tetrachloroethane 105.52
    2-methyl-cyclohexyl acetate 41.49
    tetrabutyl urea 30.69
    diisobutyl methanol 7.91
    2-phenylethanol 12.87
    styrene 10.38
    dioctyl adipate 36.22
    dimethyl sulfate 29.25
    ethyl butyrate 32.27
    methyl lactate 11.41
    butyl lactate 41.77
    diethyl carbonate 18.34
    propanediol butyl ether 28.16
    triethyl orthoformate 35.21
    p-tert-butyltoluene 9.8
    methyl 4-tert-butylbenzoate 61.03
    morpholine 33.42
    tert-butylamine 4.79
    n-dodecanol 4.88
    dimethoxymethane 17.63
    ethylene carbonate 29.88
    cyrene 50.4
    2-ethoxyethyl acetate 62.63
    2-ethylhexyl acetate 28.72
    1,2,4-trichlorobenzene 45.07
    4-methylpyridine 28.09
    dibutyl ether 24.53
    2,6-dimethyl-4-heptanol 7.91
    DEF 32.82
    dimethyl isosorbide 116.12
    tetrachloroethylene 62.02
    eugenol 44.98
    triacetin 71.67
    span 80 40.39
    1,4-butanediol 2.15
    1,1-dichloroethane 31.39
    2-methyl-1-pentanol 9.01
    methyl formate 7.02
    2-methyl-1-butanol 6.56
    n-decane 2.31
    butyronitrile 6.25
    3,7-dimethyl-1-octanol 13.43
    1-chlorooctane 12.58
    1-chlorotetradecane 3.73
    n-nonane 2.07
    undecane 1.38
    tert-butylcyclohexane 4.02
    cyclooctane 2.35
    cyclopentanol 13.7
    tetrahydropyran 33.5
    tert-amyl methyl ether 19.39
    2,5,8-trioxanonane 72.04
    1-hexene 5.89
    2-isopropoxyethanol 15.33
    2,2,2-trifluoroethanol 7.14
    methyl butyrate 37.71

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction