Isostearyl Palmitate

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  • Identifiers

    CAS number
    72576-80-8

    Molecular formula
    C34H68O2

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC(C)C

    Safety labels

  • Odor profile

    Fragrance
    Waxy 78.21%
    Fatty 60.52%
    Oily 49.47%
    Odorless 33.19%
    Creamy 20.94%
    Sweet 20.62%
    Balsamic 17.76%
    Clean 16.96%
    Fishy 16.31%
    Dairy 16.15%

     

    Flavor
    Waxy 55.24%
    Mild 40.12%
    Fatty 37.08%
    Bland 34.68%
    Oily 34.57%
    Faint 30.2%
    Alkane 29.61%
    Fat 27.31%
    Slightly waxy 25.01%
    Delicate 23.18%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    16.0

    pKa est.
    9.25 (weak base)

    Molecular weight
    508.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    535°C

    Flash point

    • 240.8 ˚C est.

  • Synonyms

    • Isostearyl palmitate
    • Isooctadecyl palmitate
    • 72576-80-8
    • Hexadecanoic acid, isooctadecyl ester
    • 9EHU0R7ER1
    • Isooctadecyl hexadecanoate
    • EINECS 276-719-0
    • PROTACHEM ISP
    • JEECHEM ISP
    • DERMOL ISP
    • NIKKOL ISP
    • DUB PIS
    • EC 276-719-0
    • PELEMOL I-1816
    • AEC ISOSTEARYL PALMITATE
    • DTXSID70222898
    • NS-118D
    • 276-719-0
    • RefChem:792358
    • DTXCID00145389
    • ISOSTEARYL PALMITATE [INCI]
    • 16-methylheptadecyl Hexadecanoate
    • UNII-9EHU0R7ER1
    • Hexadecanoic acid,isooctadecyl ester
    • SCHEMBL33645
    • 16-Methylheptadecyl palmitate
    • SAMYFBLRCRWESN-UHFFFAOYSA-N
    • NS00010216
    • Q27272445
    • 72576-80-8

  • Applications

    Isostearyl Palmitate (CAS 72576-80-8) is a branched fatty ester used primarily as an emollient and conditioning agent in cosmetics and personal care, providing slip and a soft feel in creams, lotions, and makeup. It also serves as a solvent and carrier for fragrance oils in perfumery formulations, helping to deliver volatile essences with a light, non-greasy rheology. In polymer and plastics processing, it functions as a plasticizer/processing aid to improve flexibility and workability of certain oleochemical-based materials. It can act as a vehicle for active ingredients in topical formulations, aiding spreadability and skin feel. In coatings, inks, and adhesives, it is used as a slip/conditioning additive to improve glide and gloss. It may also be employed as a base oil in household cleaning products and other consumer formulations, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.0
    methanol 5.53
    isopropanol 5.74
    water 0.04
    ethyl acetate 114.38
    n-propanol 9.6
    acetone 48.66
    n-butanol 12.98
    acetonitrile 15.14
    DMF 70.1
    toluene 52.58
    isobutanol 11.88
    1,4-dioxane 102.57
    methyl acetate 60.2
    THF 289.65
    2-butanone 86.07
    n-pentanol 14.46
    sec-butanol 14.98
    n-hexane 15.85
    ethylene glycol 0.66
    NMP 408.88
    cyclohexane 84.86
    DMSO 87.42
    n-butyl acetate 149.13
    n-octanol 38.85
    chloroform 453.02
    n-propyl acetate 144.46
    acetic acid 25.96
    dichloromethane 451.14
    cyclohexanone 382.63
    propylene glycol 2.19
    isopropyl acetate 132.44
    DMAc 238.22
    2-ethoxyethanol 34.79
    isopentanol 21.93
    n-heptane 20.95
    ethyl formate 40.91
    1,2-dichloroethane 243.46
    n-hexanol 15.45
    2-methoxyethanol 27.06
    isobutyl acetate 110.53
    tetrachloromethane 122.6
    n-pentyl acetate 310.63
    transcutol 331.02
    n-heptanol 30.82
    ethylbenzene 48.7
    MIBK 112.98
    2-propoxyethanol 42.55
    tert-butanol 17.28
    MTBE 69.86
    2-butoxyethanol 83.62
    propionic acid 28.42
    o-xylene 61.44
    formic acid 5.1
    diethyl ether 46.37
    m-xylene 47.01
    p-xylene 75.63
    chlorobenzene 122.53
    dimethyl carbonate 33.61
    n-octane 12.36
    formamide 10.72
    cyclopentanone 347.09
    2-pentanone 96.64
    anisole 93.73
    cyclopentyl methyl ether 204.97
    gamma-butyrolactone 317.04
    1-methoxy-2-propanol 36.29
    pyridine 132.97
    3-pentanone 105.84
    furfural 213.18
    n-dodecane 5.92
    diethylene glycol 13.01
    diisopropyl ether 41.71
    tert-amyl alcohol 36.45
    acetylacetone 174.19
    n-hexadecane 7.52
    acetophenone 150.31
    methyl propionate 80.89
    isopentyl acetate 175.47
    trichloroethylene 490.28
    n-nonanol 44.51
    cyclohexanol 59.17
    benzyl alcohol 37.15
    2-ethylhexanol 33.8
    isooctanol 41.91
    dipropyl ether 104.72
    1,2-dichlorobenzene 192.48
    ethyl lactate 48.82
    propylene carbonate 222.0
    n-methylformamide 22.89
    2-pentanol 15.39
    n-pentane 8.44
    1-propoxy-2-propanol 65.57
    1-methoxy-2-propyl acetate 165.28
    2-(2-methoxypropoxy) propanol 110.63
    mesitylene 45.14
    ε-caprolactone 367.52
    p-cymene 54.46
    epichlorohydrin 321.07
    1,1,1-trichloroethane 371.43
    2-aminoethanol 2.96
    morpholine-4-carbaldehyde 197.0
    sulfolane 608.96
    2,2,4-trimethylpentane 16.93
    2-methyltetrahydrofuran 256.0
    n-hexyl acetate 258.6
    isooctane 7.91
    2-(2-butoxyethoxy)ethanol 120.82
    sec-butyl acetate 143.31
    tert-butyl acetate 223.04
    decalin 35.05
    glycerin 5.18
    diglyme 362.91
    acrylic acid 20.55
    isopropyl myristate 85.13
    n-butyric acid 77.1
    acetyl acetate 103.1
    di(2-ethylhexyl) phthalate 63.25
    ethyl propionate 146.0
    nitromethane 78.8
    1,2-diethoxyethane 188.58
    benzonitrile 61.96
    trioctyl phosphate 45.03
    1-bromopropane 130.57
    gamma-valerolactone 438.72
    n-decanol 26.07
    triethyl phosphate 131.74
    4-methyl-2-pentanol 18.24
    propionitrile 22.6
    vinylene carbonate 151.66
    1,1,2-trichlorotrifluoroethane 201.22
    DMS 115.86
    cumene 41.08
    2-octanol 37.61
    2-hexanone 119.9
    octyl acetate 94.39
    limonene 100.71
    1,2-dimethoxyethane 140.16
    ethyl orthosilicate 131.98
    tributyl phosphate 68.61
    diacetone alcohol 130.85
    N,N-dimethylaniline 80.78
    acrylonitrile 22.92
    aniline 40.67
    1,3-propanediol 7.35
    bromobenzene 174.35
    dibromomethane 263.03
    1,1,2,2-tetrachloroethane 497.11
    2-methyl-cyclohexyl acetate 198.24
    tetrabutyl urea 108.21
    diisobutyl methanol 37.06
    2-phenylethanol 38.08
    styrene 53.79
    dioctyl adipate 152.91
    dimethyl sulfate 106.78
    ethyl butyrate 203.03
    methyl lactate 31.59
    butyl lactate 148.39
    diethyl carbonate 112.28
    propanediol butyl ether 58.84
    triethyl orthoformate 193.46
    p-tert-butyltoluene 50.23
    methyl 4-tert-butylbenzoate 230.86
    morpholine 118.39
    tert-butylamine 15.55
    n-dodecanol 17.57
    dimethoxymethane 55.47
    ethylene carbonate 139.68
    cyrene 125.63
    2-ethoxyethyl acetate 279.96
    2-ethylhexyl acetate 173.78
    1,2,4-trichlorobenzene 244.52
    4-methylpyridine 135.79
    dibutyl ether 148.0
    2,6-dimethyl-4-heptanol 37.06
    DEF 152.67
    dimethyl isosorbide 331.01
    tetrachloroethylene 291.9
    eugenol 130.78
    triacetin 301.23
    span 80 109.07
    1,4-butanediol 4.19
    1,1-dichloroethane 185.08
    2-methyl-1-pentanol 26.46
    methyl formate 20.92
    2-methyl-1-butanol 22.54
    n-decane 16.02
    butyronitrile 29.56
    3,7-dimethyl-1-octanol 51.0
    1-chlorooctane 74.31
    1-chlorotetradecane 20.79
    n-nonane 15.56
    undecane 8.9
    tert-butylcyclohexane 23.68
    cyclooctane 27.12
    cyclopentanol 49.55
    tetrahydropyran 181.43
    tert-amyl methyl ether 97.93
    2,5,8-trioxanonane 183.51
    1-hexene 30.44
    2-isopropoxyethanol 38.84
    2,2,2-trifluoroethanol 21.66
    methyl butyrate 194.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction