Isostearyl glycolate

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  • Identifiers

    CAS number
    159317-32-5

    Molecular formula
    C20H40O3

    SMILES
    CC(C)CCCCCCCCCCCCCCCOC(=O)CO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 72.6%
    Fatty 57.66%
    Oily 42.61%
    Odorless 34.98%
    Sweet 24.52%
    Creamy 24.23%
    Milky 21.28%
    Buttery 19.88%
    Clean 19.77%
    Dairy 18.3%

     

    Flavor
    Waxy 58.87%
    Oily 46.08%
    Fatty 44.91%
    Mild 43.29%
    Soapy 33.71%
    Bland 32.75%
    Faint 30.91%
    Fat 30.84%
    Coconut 28.74%
    Creamy 27.21%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.0

    pKa est.
    7.22 (neutral)

    Molecular weight
    328.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    400°C

    Flash point

    • 184.89 ˚C est.

  • Synonyms

    • isostearyl glycolate
    • Dermol isgl
    • Spectron-IG76
    • 3AX6769D2H
    • 159317-32-5
    • Isostearyl glycolate [INCI]
    • UNII-3AX6769D2H
    • Acetic acid, 2-hydroxy-, isooctadecyl ester
    • RefChem:149992
    • DTXSID201019999
    • 16-METHYLHEPTADECYL 2-HYDROXYACETATE
    • SCHEMBL297759
    • PDWHIWRZNHIGLA-UHFFFAOYSA-N
    • Q27256981
    • 159317-32-5

  • Applications

    Isostearyl glycolate (CAS 159317-32-5) is commonly used in cosmetics and personal care as an emollient and solvent, improving skin feel and serving as a vehicle for active ingredients and fragrance components; in perfumery it acts as a fragrance solvent and carrier for aroma compounds; in coatings and inks it can function as a processing aid and solvent to improve compatibility and flow; in polymer formulations it may be used as a processing aid or plasticizer to enhance flexibility; and in household and industrial cleaning products it serves as a mild solvent and conditioning agent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 17.36
    methanol 19.85
    isopropanol 22.76
    water 0.02
    ethyl acetate 148.25
    n-propanol 24.55
    acetone 77.08
    n-butanol 32.98
    acetonitrile 26.08
    DMF 120.47
    toluene 45.93
    isobutanol 28.56
    1,4-dioxane 142.05
    methyl acetate 77.93
    THF 472.14
    2-butanone 122.73
    n-pentanol 32.57
    sec-butanol 35.38
    n-hexane 10.53
    ethylene glycol 1.63
    NMP 369.4
    cyclohexane 58.21
    DMSO 227.94
    n-butyl acetate 201.33
    n-octanol 53.95
    chloroform 353.13
    n-propyl acetate 220.04
    acetic acid 41.53
    dichloromethane 365.83
    cyclohexanone 447.66
    propylene glycol 6.71
    isopropyl acetate 172.74
    DMAc 258.7
    2-ethoxyethanol 95.53
    isopentanol 57.47
    n-heptane 15.21
    ethyl formate 60.26
    1,2-dichloroethane 285.07
    n-hexanol 34.44
    2-methoxyethanol 83.5
    isobutyl acetate 148.43
    tetrachloromethane 88.06
    n-pentyl acetate 320.16
    transcutol 650.74
    n-heptanol 48.66
    ethylbenzene 42.31
    MIBK 179.94
    2-propoxyethanol 102.96
    tert-butanol 71.8
    MTBE 128.74
    2-butoxyethanol 149.56
    propionic acid 43.08
    o-xylene 53.73
    formic acid 7.5
    diethyl ether 71.04
    m-xylene 47.91
    p-xylene 63.3
    chlorobenzene 95.11
    dimethyl carbonate 31.83
    n-octane 8.4
    formamide 19.45
    cyclopentanone 417.36
    2-pentanone 152.54
    anisole 104.4
    cyclopentyl methyl ether 240.86
    gamma-butyrolactone 350.52
    1-methoxy-2-propanol 110.61
    pyridine 140.55
    3-pentanone 112.92
    furfural 253.25
    n-dodecane 4.75
    diethylene glycol 36.69
    diisopropyl ether 53.7
    tert-amyl alcohol 83.11
    acetylacetone 222.27
    n-hexadecane 5.94
    acetophenone 153.63
    methyl propionate 95.28
    isopentyl acetate 224.57
    trichloroethylene 475.99
    n-nonanol 55.23
    cyclohexanol 100.67
    benzyl alcohol 59.26
    2-ethylhexanol 54.47
    isooctanol 62.23
    dipropyl ether 116.92
    1,2-dichlorobenzene 144.5
    ethyl lactate 73.86
    propylene carbonate 207.88
    n-methylformamide 37.78
    2-pentanol 35.99
    n-pentane 6.93
    1-propoxy-2-propanol 142.79
    1-methoxy-2-propyl acetate 213.83
    2-(2-methoxypropoxy) propanol 140.76
    mesitylene 45.28
    ε-caprolactone 372.66
    p-cymene 49.49
    epichlorohydrin 423.34
    1,1,1-trichloroethane 325.01
    2-aminoethanol 8.24
    morpholine-4-carbaldehyde 269.51
    sulfolane 738.32
    2,2,4-trimethylpentane 13.73
    2-methyltetrahydrofuran 323.08
    n-hexyl acetate 261.49
    isooctane 8.79
    2-(2-butoxyethoxy)ethanol 201.01
    sec-butyl acetate 185.07
    tert-butyl acetate 290.87
    decalin 25.75
    glycerin 13.95
    diglyme 478.58
    acrylic acid 27.62
    isopropyl myristate 80.87
    n-butyric acid 130.49
    acetyl acetate 103.06
    di(2-ethylhexyl) phthalate 59.88
    ethyl propionate 172.09
    nitromethane 122.15
    1,2-diethoxyethane 250.46
    benzonitrile 81.57
    trioctyl phosphate 48.36
    1-bromopropane 137.42
    gamma-valerolactone 558.64
    n-decanol 33.93
    triethyl phosphate 106.83
    4-methyl-2-pentanol 40.17
    propionitrile 35.37
    vinylene carbonate 138.41
    1,1,2-trichlorotrifluoroethane 267.53
    DMS 113.85
    cumene 38.44
    2-octanol 51.57
    2-hexanone 169.86
    octyl acetate 94.28
    limonene 94.91
    1,2-dimethoxyethane 265.89
    ethyl orthosilicate 110.54
    tributyl phosphate 66.88
    diacetone alcohol 253.76
    N,N-dimethylaniline 81.02
    acrylonitrile 35.27
    aniline 47.9
    1,3-propanediol 23.3
    bromobenzene 124.56
    dibromomethane 226.38
    1,1,2,2-tetrachloroethane 512.8
    2-methyl-cyclohexyl acetate 183.04
    tetrabutyl urea 105.3
    diisobutyl methanol 54.71
    2-phenylethanol 62.77
    styrene 46.41
    dioctyl adipate 142.88
    dimethyl sulfate 100.75
    ethyl butyrate 216.98
    methyl lactate 47.42
    butyl lactate 174.21
    diethyl carbonate 103.87
    propanediol butyl ether 114.22
    triethyl orthoformate 177.27
    p-tert-butyltoluene 49.04
    methyl 4-tert-butylbenzoate 202.31
    morpholine 209.89
    tert-butylamine 46.95
    n-dodecanol 23.04
    dimethoxymethane 91.59
    ethylene carbonate 133.36
    cyrene 155.22
    2-ethoxyethyl acetate 301.55
    2-ethylhexyl acetate 192.06
    1,2,4-trichlorobenzene 177.35
    4-methylpyridine 139.44
    dibutyl ether 147.15
    2,6-dimethyl-4-heptanol 54.71
    DEF 200.98
    dimethyl isosorbide 355.42
    tetrachloroethylene 294.3
    eugenol 143.41
    triacetin 271.51
    span 80 135.64
    1,4-butanediol 10.56
    1,1-dichloroethane 211.23
    2-methyl-1-pentanol 52.09
    methyl formate 29.59
    2-methyl-1-butanol 48.02
    n-decane 12.01
    butyronitrile 54.46
    3,7-dimethyl-1-octanol 69.93
    1-chlorooctane 70.34
    1-chlorotetradecane 18.55
    n-nonane 11.61
    undecane 6.91
    tert-butylcyclohexane 19.55
    cyclooctane 15.62
    cyclopentanol 93.04
    tetrahydropyran 239.22
    tert-amyl methyl ether 124.38
    2,5,8-trioxanonane 259.35
    1-hexene 31.25
    2-isopropoxyethanol 96.19
    2,2,2-trifluoroethanol 25.73
    methyl butyrate 253.76

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction