Isostearyl glyceryl pentaerythrityl ether

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  • Identifiers

    CAS number
    146925-83-9

    Molecular formula
    C26H54O6

    SMILES
    CC(C)CCCCCCCCCCCCCCCOCC(COCC(CO)(CO)CO)O

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 43.34%
    Oily 36.85%
    Woody 34.41%
    Odorless 33.01%
    Fresh 31.66%
    Sweet 30.41%
    Amber 29.27%
    Alcoholic 27.79%
    Fruity 27.49%
    Sandalwood 26.27%

     

    Flavor
    Waxy 39.81%
    Mild 35.44%
    Fatty 29.09%
    Bland 27.36%
    Oily 26.68%
    Odorless 25.21%
    Floral 23.32%
    Sweet 22.3%
    Slightly waxy 21.44%
    Sweet-like 21.27%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.9

    pKa est.
    6.4 (neutral)

    Molecular weight
    462.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    699°C

    Flash point

    • 247.22 ˚C est.

  • Synonyms

    • Isostearyl Glyceryl Pentaerythrityl Ether
    • 3X85950A89
    • EC 416-380-1
    • Isostearyl glyceryl pentaerythrityl ether [INCI]
    • 1,3-Propanediol, 2-(hydroxymethyl)-2-((2-hydroxy-3-(isooctadecyloxy)propoxy)methyl)-
    • 2-(hydroxymethyl)-2-((2-hydroxy-3-(isooctadecyloxy)propoxy)methyl)-1,3-propanediol
    • 1,3-Propanediol, 2-(hydroxymethyl)-2-[[2-hydroxy-3-(isooctadecyloxy)propoxy]methyl]-
    • 2-(hydroxymethyl)-2-[[2-hydroxy-3-(isooctadecyloxy)propoxy]methyl]-1,3-propanediol
    • RefChem:792355
    • 416-380-1
    • UNII-3X85950A89
    • 146925-83-9
    • QWVUXEBWAZOACQ-UHFFFAOYSA-N
    • Q27258169
    • 146925-83-9

  • Applications

    Isostearyl glyceryl pentaerythrityl ether (CAS 146925-83-9) is widely used as an emollient and conditioning agent in cosmetics and personal care, providing a soft, smooth feel to skin and hair. It also serves as a solvent/carrier for fragrances and actives in perfumery and skincare formulations, and can act as an emulsifier or nonionic surfactant to help stabilize oil-in-water systems. With its lubricious character and viscosity-modifying potential, it is commonly used to adjust texture and rheology in products. In industrial contexts, it can be used as a processing aid, plasticizer, or additive in polymer and coating formulations to improve workability and flexibility. These applications are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.9
    methanol 18.79
    isopropanol 7.26
    water 0.53
    ethyl acetate 16.45
    n-propanol 12.92
    acetone 25.48
    n-butanol 11.93
    acetonitrile 5.11
    DMF 62.71
    toluene 9.38
    isobutanol 11.64
    1,4-dioxane 37.0
    methyl acetate 15.88
    THF 116.93
    2-butanone 27.04
    n-pentanol 11.89
    sec-butanol 11.02
    n-hexane 1.42
    ethylene glycol 3.35
    NMP 149.89
    cyclohexane 6.16
    DMSO 153.42
    n-butyl acetate 19.91
    n-octanol 18.0
    chloroform 71.39
    n-propyl acetate 23.99
    acetic acid 45.69
    dichloromethane 60.04
    cyclohexanone 96.83
    propylene glycol 7.89
    isopropyl acetate 20.05
    DMAc 112.06
    2-ethoxyethanol 36.94
    isopentanol 14.69
    n-heptane 2.43
    ethyl formate 17.49
    1,2-dichloroethane 38.66
    n-hexanol 10.71
    2-methoxyethanol 42.63
    isobutyl acetate 21.08
    tetrachloromethane 18.62
    n-pentyl acetate 46.29
    transcutol 146.23
    n-heptanol 18.77
    ethylbenzene 7.03
    MIBK 27.93
    2-propoxyethanol 32.88
    tert-butanol 16.25
    MTBE 15.64
    2-butoxyethanol 56.95
    propionic acid 25.56
    o-xylene 11.5
    formic acid 21.83
    diethyl ether 7.79
    m-xylene 9.62
    p-xylene 9.36
    chlorobenzene 14.69
    dimethyl carbonate 14.98
    n-octane 1.51
    formamide 29.55
    cyclopentanone 120.12
    2-pentanone 25.57
    anisole 15.04
    cyclopentyl methyl ether 52.53
    gamma-butyrolactone 113.24
    1-methoxy-2-propanol 40.43
    pyridine 30.67
    3-pentanone 22.83
    furfural 84.55
    n-dodecane 0.99
    diethylene glycol 20.21
    diisopropyl ether 5.77
    tert-amyl alcohol 20.74
    acetylacetone 49.8
    n-hexadecane 1.14
    acetophenone 32.93
    methyl propionate 22.74
    isopentyl acetate 28.26
    trichloroethylene 85.66
    n-nonanol 18.14
    cyclohexanol 29.37
    benzyl alcohol 18.1
    2-ethylhexanol 12.98
    isooctanol 20.81
    dipropyl ether 14.23
    1,2-dichlorobenzene 20.89
    ethyl lactate 26.86
    propylene carbonate 66.93
    n-methylformamide 27.45
    2-pentanol 8.87
    n-pentane 1.18
    1-propoxy-2-propanol 35.7
    1-methoxy-2-propyl acetate 37.43
    2-(2-methoxypropoxy) propanol 46.8
    mesitylene 8.28
    ε-caprolactone 92.04
    p-cymene 9.18
    epichlorohydrin 91.35
    1,1,1-trichloroethane 42.76
    2-aminoethanol 10.13
    morpholine-4-carbaldehyde 94.02
    sulfolane 284.28
    2,2,4-trimethylpentane 2.5
    2-methyltetrahydrofuran 56.79
    n-hexyl acetate 44.1
    isooctane 1.38
    2-(2-butoxyethoxy)ethanol 60.85
    sec-butyl acetate 21.67
    tert-butyl acetate 41.36
    decalin 3.8
    glycerin 20.19
    diglyme 127.0
    acrylic acid 24.33
    isopropyl myristate 13.54
    n-butyric acid 43.12
    acetyl acetate 18.84
    di(2-ethylhexyl) phthalate 18.82
    ethyl propionate 20.56
    nitromethane 61.23
    1,2-diethoxyethane 28.71
    benzonitrile 16.29
    trioctyl phosphate 15.55
    1-bromopropane 14.44
    gamma-valerolactone 162.32
    n-decanol 10.82
    triethyl phosphate 24.06
    4-methyl-2-pentanol 10.1
    propionitrile 6.74
    vinylene carbonate 50.56
    1,1,2-trichlorotrifluoroethane 120.23
    DMS 23.57
    cumene 7.14
    2-octanol 14.45
    2-hexanone 24.81
    octyl acetate 18.8
    limonene 15.72
    1,2-dimethoxyethane 55.32
    ethyl orthosilicate 24.69
    tributyl phosphate 17.66
    diacetone alcohol 62.63
    N,N-dimethylaniline 16.68
    acrylonitrile 9.2
    aniline 13.85
    1,3-propanediol 16.95
    bromobenzene 14.83
    dibromomethane 36.25
    1,1,2,2-tetrachloroethane 93.03
    2-methyl-cyclohexyl acetate 34.54
    tetrabutyl urea 25.83
    diisobutyl methanol 10.76
    2-phenylethanol 16.82
    styrene 6.48
    dioctyl adipate 29.65
    dimethyl sulfate 55.06
    ethyl butyrate 25.84
    methyl lactate 27.3
    butyl lactate 49.73
    diethyl carbonate 15.34
    propanediol butyl ether 49.14
    triethyl orthoformate 30.12
    p-tert-butyltoluene 9.62
    methyl 4-tert-butylbenzoate 57.46
    morpholine 56.32
    tert-butylamine 8.7
    n-dodecanol 6.88
    dimethoxymethane 36.9
    ethylene carbonate 44.06
    cyrene 67.64
    2-ethoxyethyl acetate 51.25
    2-ethylhexyl acetate 23.39
    1,2,4-trichlorobenzene 29.7
    4-methylpyridine 24.05
    dibutyl ether 16.2
    2,6-dimethyl-4-heptanol 10.76
    DEF 42.52
    dimethyl isosorbide 95.31
    tetrachloroethylene 62.41
    eugenol 46.5
    triacetin 63.85
    span 80 43.75
    1,4-butanediol 8.46
    1,1-dichloroethane 25.37
    2-methyl-1-pentanol 15.09
    methyl formate 23.56
    2-methyl-1-butanol 15.39
    n-decane 2.27
    butyronitrile 7.76
    3,7-dimethyl-1-octanol 17.19
    1-chlorooctane 11.38
    1-chlorotetradecane 3.16
    n-nonane 2.02
    undecane 1.39
    tert-butylcyclohexane 2.99
    cyclooctane 2.66
    cyclopentanol 32.44
    tetrahydropyran 43.18
    tert-amyl methyl ether 19.59
    2,5,8-trioxanonane 73.18
    1-hexene 3.73
    2-isopropoxyethanol 29.48
    2,2,2-trifluoroethanol 30.95
    methyl butyrate 33.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction