Isostearic diethanolamide

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  • Identifiers

    CAS number
    52794-79-3

    Molecular formula
    C22H45NO3

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)N(CCO)CCO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 43.98%
    Odorless 35.14%
    Woody 35.06%
    Oily 30.14%
    Fresh 27.9%
    Animal 26.41%
    Fatty 26.11%
    Fishy 25.84%
    Cooling 24.88%
    Sweet 24.72%

     

    Flavor
    Bland 37.41%
    Mild 35.09%
    Odorless 34.41%
    Fatty 25.12%
    Waxy 25.05%
    Faint 24.81%
    Slightly waxy 22.3%
    Delicate 21.21%
    Bay oil 20.99%
    Oily 20.47%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.5

    pKa est.
    7.32 (neutral)

    Molecular weight
    371.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    510°C

    Flash point

    • 222.19 ˚C est.

  • Synonyms

    • Isostearic diethanolamide
    • Isooctadecanamide, N,N-bis(2-hydroxyethyl)-
    • Isostearamide DEA
    • Isostearic acid diethanolamide
    • N,N-Bis(2-hydroxyethyl)isooctadecan-1-amide
    • INCROMIDE ISDEA
    • COLAMID ISA
    • MACKAMIDE ISA-D
    • B8I784TV08
    • EINECS 258-193-4
    • N,N-Bis(2-hydroxyethyl)isooctadecanamide
    • DTXSID1068807
    • ISOSTEAROYL DIETHANOLAMIDE
    • ISOSTEARIC ACID DIETHANOLAMIDE (DEA)
    • N,N-BIS(2-HYDROXYETHYL)ISOSTEARAMIDE
    • RefChem:792348
    • DTXCID8041296
    • ISOSTEARAMIDE DEA [INCI]
    • 52794-79-3
    • n,n-bis(2-hydroxyethyl)-16-methylheptadecanamide
    • UNII-B8I784TV08
    • SCHEMBL356466
    • XHUUHJFOYQREKL-UHFFFAOYSA-N
    • DB-298542
    • NS00013793
    • Q27274500
    • 52794-79-3

  • Applications

    Isostearic diethanolamide (CAS 52794-79-3) is a nonionic surfactant derived from isostearic acid that is commonly used as a surfactant, emulsifier, and thickener in cosmetic and personal-care formulations (for example shampoos, cleansers, and gels), often providing foam stability and rheology modification. In household and industrial cleaners, it serves as a wetting agent, foam booster, and dispersant to improve cleaning performance. In the polymer and coatings area, ISDEA acts as an emulsifier and stabilizer for polymer emulsions and as a surface-active additive to paints, coatings, and inks to improve wetting and leveling. In adhesives, it can function as a dispersant or wetting agent to aid adhesion and formulation stability. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.26
    methanol 26.77
    isopropanol 10.13
    water 0.18
    ethyl acetate 58.02
    n-propanol 16.14
    acetone 42.98
    n-butanol 18.05
    acetonitrile 18.98
    DMF 94.22
    toluene 20.44
    isobutanol 17.3
    1,4-dioxane 71.57
    methyl acetate 44.38
    THF 205.25
    2-butanone 60.59
    n-pentanol 17.71
    sec-butanol 18.94
    n-hexane 2.72
    ethylene glycol 2.47
    NMP 271.17
    cyclohexane 16.17
    DMSO 173.85
    n-butyl acetate 71.12
    n-octanol 23.45
    chloroform 198.17
    n-propyl acetate 90.72
    acetic acid 54.31
    dichloromethane 204.34
    cyclohexanone 235.03
    propylene glycol 6.63
    isopropyl acetate 66.52
    DMAc 226.83
    2-ethoxyethanol 56.81
    isopentanol 27.68
    n-heptane 3.35
    ethyl formate 41.55
    1,2-dichloroethane 136.1
    n-hexanol 15.62
    2-methoxyethanol 55.39
    isobutyl acetate 60.04
    tetrachloromethane 52.16
    n-pentyl acetate 125.68
    transcutol 282.51
    n-heptanol 24.79
    ethylbenzene 17.05
    MIBK 67.31
    2-propoxyethanol 51.01
    tert-butanol 29.23
    MTBE 40.21
    2-butoxyethanol 81.69
    propionic acid 39.61
    o-xylene 25.61
    formic acid 17.82
    diethyl ether 22.04
    m-xylene 18.86
    p-xylene 26.64
    chlorobenzene 46.14
    dimethyl carbonate 23.12
    n-octane 2.18
    formamide 31.05
    cyclopentanone 220.5
    2-pentanone 60.63
    anisole 40.55
    cyclopentyl methyl ether 90.81
    gamma-butyrolactone 226.42
    1-methoxy-2-propanol 56.64
    pyridine 80.55
    3-pentanone 55.67
    furfural 176.03
    n-dodecane 1.39
    diethylene glycol 28.2
    diisopropyl ether 13.82
    tert-amyl alcohol 37.55
    acetylacetone 100.2
    n-hexadecane 1.66
    acetophenone 75.46
    methyl propionate 49.34
    isopentyl acetate 79.62
    trichloroethylene 246.38
    n-nonanol 24.15
    cyclohexanol 52.4
    benzyl alcohol 35.2
    2-ethylhexanol 21.2
    isooctanol 27.61
    dipropyl ether 31.61
    1,2-dichlorobenzene 66.44
    ethyl lactate 45.75
    propylene carbonate 139.31
    n-methylformamide 38.22
    2-pentanol 14.93
    n-pentane 1.98
    1-propoxy-2-propanol 55.93
    1-methoxy-2-propyl acetate 85.28
    2-(2-methoxypropoxy) propanol 70.97
    mesitylene 16.42
    ε-caprolactone 213.73
    p-cymene 17.98
    epichlorohydrin 208.61
    1,1,1-trichloroethane 149.33
    2-aminoethanol 9.81
    morpholine-4-carbaldehyde 168.87
    sulfolane 437.23
    2,2,4-trimethylpentane 4.22
    2-methyltetrahydrofuran 128.64
    n-hexyl acetate 98.85
    isooctane 1.96
    2-(2-butoxyethoxy)ethanol 94.92
    sec-butyl acetate 69.17
    tert-butyl acetate 97.88
    decalin 6.95
    glycerin 16.26
    diglyme 230.09
    acrylic acid 32.49
    isopropyl myristate 26.48
    n-butyric acid 85.92
    acetyl acetate 53.1
    di(2-ethylhexyl) phthalate 33.69
    ethyl propionate 68.47
    nitromethane 108.98
    1,2-diethoxyethane 79.95
    benzonitrile 46.14
    trioctyl phosphate 23.71
    1-bromopropane 53.3
    gamma-valerolactone 324.57
    n-decanol 14.81
    triethyl phosphate 51.17
    4-methyl-2-pentanol 15.73
    propionitrile 22.66
    vinylene carbonate 110.79
    1,1,2-trichlorotrifluoroethane 188.66
    DMS 55.85
    cumene 14.93
    2-octanol 20.38
    2-hexanone 67.98
    octyl acetate 36.35
    limonene 29.72
    1,2-dimethoxyethane 135.39
    ethyl orthosilicate 49.41
    tributyl phosphate 33.72
    diacetone alcohol 108.3
    N,N-dimethylaniline 34.67
    acrylonitrile 26.53
    aniline 28.04
    1,3-propanediol 19.46
    bromobenzene 50.29
    dibromomethane 115.42
    1,1,2,2-tetrachloroethane 241.65
    2-methyl-cyclohexyl acetate 72.13
    tetrabutyl urea 49.38
    diisobutyl methanol 16.92
    2-phenylethanol 32.67
    styrene 19.1
    dioctyl adipate 57.61
    dimethyl sulfate 72.25
    ethyl butyrate 76.28
    methyl lactate 35.58
    butyl lactate 90.39
    diethyl carbonate 45.66
    propanediol butyl ether 64.93
    triethyl orthoformate 67.87
    p-tert-butyltoluene 17.01
    methyl 4-tert-butylbenzoate 93.54
    morpholine 105.5
    tert-butylamine 17.21
    n-dodecanol 9.82
    dimethoxymethane 49.08
    ethylene carbonate 99.01
    cyrene 95.59
    2-ethoxyethyl acetate 141.27
    2-ethylhexyl acetate 66.14
    1,2,4-trichlorobenzene 85.02
    4-methylpyridine 70.37
    dibutyl ether 38.5
    2,6-dimethyl-4-heptanol 16.92
    DEF 110.95
    dimethyl isosorbide 155.29
    tetrachloroethylene 171.37
    eugenol 78.98
    triacetin 128.1
    span 80 62.64
    1,4-butanediol 9.88
    1,1-dichloroethane 95.15
    2-methyl-1-pentanol 25.99
    methyl formate 29.93
    2-methyl-1-butanol 26.83
    n-decane 3.19
    butyronitrile 26.74
    3,7-dimethyl-1-octanol 25.4
    1-chlorooctane 20.42
    1-chlorotetradecane 5.54
    n-nonane 2.93
    undecane 1.94
    tert-butylcyclohexane 5.13
    cyclooctane 3.68
    cyclopentanol 51.95
    tetrahydropyran 101.07
    tert-amyl methyl ether 45.02
    2,5,8-trioxanonane 120.86
    1-hexene 9.47
    2-isopropoxyethanol 48.78
    2,2,2-trifluoroethanol 39.1
    methyl butyrate 110.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction