Isostearamidopropyl morpholine oxide

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  • Identifiers

    CAS number
    123813-16-1

    Molecular formula
    C25H50N2O3

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)NCCC[N+]1(CCOCC1)[O-]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 34.08%
    Fishy 33.77%
    Waxy 32.6%
    Savory 31.83%
    Cooling 30.68%
    Animal 30.49%
    Meaty 29.87%
    Oily 25.25%
    Fatty 23.43%
    Woody 23.3%

     

    Flavor
    Bland 32.96%
    Mild 28.59%
    Odorless 28.0%
    Faint 22.6%
    Slightly waxy 21.49%
    Fatty 21.32%
    Delicate 20.74%
    Bay oil 20.34%
    Cedarleaf 19.95%
    Beer 19.57%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.1

    pKa est.
    6.6 (neutral)

    Molecular weight
    426.7 g/mol

    Flash point

    • -221.04 ˚C est.

  • Synonyms

    • Isostearamidopropyl Morpholine Oxide
    • isostearamidopropylmorpholine oxide
    • 9I551GQ82I
    • UNII-9I551GQ82I
    • 123813-16-1
    • Isostearamidopropyl morpholine oxide [INCI]
    • Isooctadecanamide, N-(3-(4-oxido-4-morpholinyl)propyl)-
    • Isooctadecanamide, N-(3-(4-morpholinyl)propyl)-, N-oxide
    • RefChem:149984
    • SCHEMBL30296611
    • PEWFHTFASPEWFH-UHFFFAOYSA-N
    • DTXSID001021695
    • Q27272576
    • 123813-16-1

  • Applications

    Isostearamidopropyl morpholine oxide, CAS 123813-16-1, is a nonionic surfactant with an isostearoyl amide tail and a morpholine oxide head that serves as an emulsifier and wetting agent in cosmetic and personal care formulations to stabilize oil-in-water blends and improve cleansing performance. It is commonly used in household and industrial cleaning products to enhance wetting, dispersion, foam characteristics, and cleaning efficiency. In coatings and inks, it acts as a pigment dispersant and wetting agent to improve substrate coverage and formulation stability. In polymers and plastics, it can serve as a stabilizer or processing aid in emulsion polymerization and related formulations. Additionally, it is often evaluated as an agricultural adjuvant to improve spray coverage. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.53
    methanol 13.53
    isopropanol 5.43
    water 0.35
    ethyl acetate 35.14
    n-propanol 10.03
    acetone 30.17
    n-butanol 9.5
    acetonitrile 12.5
    DMF 45.59
    toluene 19.66
    isobutanol 8.98
    1,4-dioxane 42.48
    methyl acetate 30.4
    THF 82.58
    2-butanone 39.28
    n-pentanol 9.71
    sec-butanol 9.77
    n-hexane 1.44
    ethylene glycol 2.0
    NMP 170.29
    cyclohexane 5.69
    DMSO 68.65
    n-butyl acetate 33.38
    n-octanol 12.29
    chloroform 221.95
    n-propyl acetate 39.53
    acetic acid 60.98
    dichloromethane 204.52
    cyclohexanone 123.81
    propylene glycol 4.28
    isopropyl acetate 30.06
    DMAc 142.37
    2-ethoxyethanol 31.95
    isopentanol 11.76
    n-heptane 1.55
    ethyl formate 27.22
    1,2-dichloroethane 95.11
    n-hexanol 8.12
    2-methoxyethanol 29.35
    isobutyl acetate 27.42
    tetrachloromethane 40.04
    n-pentyl acetate 52.11
    transcutol 169.97
    n-heptanol 11.33
    ethylbenzene 11.26
    MIBK 26.19
    2-propoxyethanol 30.09
    tert-butanol 8.42
    MTBE 13.02
    2-butoxyethanol 40.76
    propionic acid 29.3
    o-xylene 19.03
    formic acid 24.15
    diethyl ether 10.67
    m-xylene 13.77
    p-xylene 16.55
    chlorobenzene 40.98
    dimethyl carbonate 15.93
    n-octane 0.97
    formamide 30.32
    cyclopentanone 114.5
    2-pentanone 31.96
    anisole 23.88
    cyclopentyl methyl ether 44.23
    gamma-butyrolactone 132.94
    1-methoxy-2-propanol 25.09
    pyridine 57.34
    3-pentanone 35.07
    furfural 124.98
    n-dodecane 0.76
    diethylene glycol 17.73
    diisopropyl ether 5.37
    tert-amyl alcohol 13.91
    acetylacetone 55.98
    n-hexadecane 0.91
    acetophenone 45.68
    methyl propionate 31.77
    isopentyl acetate 36.34
    trichloroethylene 220.84
    n-nonanol 13.16
    cyclohexanol 26.17
    benzyl alcohol 23.34
    2-ethylhexanol 10.58
    isooctanol 12.12
    dipropyl ether 13.29
    1,2-dichlorobenzene 56.89
    ethyl lactate 24.45
    propylene carbonate 87.13
    n-methylformamide 25.21
    2-pentanol 7.19
    n-pentane 1.05
    1-propoxy-2-propanol 28.45
    1-methoxy-2-propyl acetate 46.65
    2-(2-methoxypropoxy) propanol 50.78
    mesitylene 9.77
    ε-caprolactone 130.56
    p-cymene 10.16
    epichlorohydrin 125.61
    1,1,1-trichloroethane 103.44
    2-aminoethanol 6.48
    morpholine-4-carbaldehyde 106.77
    sulfolane 217.95
    2,2,4-trimethylpentane 1.91
    2-methyltetrahydrofuran 61.56
    n-hexyl acetate 48.3
    isooctane 0.73
    2-(2-butoxyethoxy)ethanol 60.56
    sec-butyl acetate 31.41
    tert-butyl acetate 37.9
    decalin 3.11
    glycerin 11.11
    diglyme 136.0
    acrylic acid 27.97
    isopropyl myristate 14.9
    n-butyric acid 46.62
    acetyl acetate 39.32
    di(2-ethylhexyl) phthalate 24.19
    ethyl propionate 33.2
    nitromethane 93.34
    1,2-diethoxyethane 42.56
    benzonitrile 31.41
    trioctyl phosphate 14.41
    1-bromopropane 33.85
    gamma-valerolactone 176.1
    n-decanol 8.21
    triethyl phosphate 33.27
    4-methyl-2-pentanol 6.86
    propionitrile 11.6
    vinylene carbonate 77.87
    1,1,2-trichlorotrifluoroethane 140.95
    DMS 37.67
    cumene 9.5
    2-octanol 8.69
    2-hexanone 31.4
    octyl acetate 21.23
    limonene 15.3
    1,2-dimethoxyethane 55.31
    ethyl orthosilicate 30.5
    tributyl phosphate 20.68
    diacetone alcohol 40.79
    N,N-dimethylaniline 19.16
    acrylonitrile 17.07
    aniline 24.89
    1,3-propanediol 10.93
    bromobenzene 45.35
    dibromomethane 105.79
    1,1,2,2-tetrachloroethane 198.49
    2-methyl-cyclohexyl acetate 42.83
    tetrabutyl urea 27.95
    diisobutyl methanol 6.81
    2-phenylethanol 21.13
    styrene 12.99
    dioctyl adipate 35.5
    dimethyl sulfate 49.99
    ethyl butyrate 37.69
    methyl lactate 22.07
    butyl lactate 42.64
    diethyl carbonate 27.38
    propanediol butyl ether 34.24
    triethyl orthoformate 37.82
    p-tert-butyltoluene 8.79
    methyl 4-tert-butylbenzoate 55.84
    morpholine 56.82
    tert-butylamine 5.38
    n-dodecanol 5.49
    dimethoxymethane 25.86
    ethylene carbonate 66.88
    cyrene 62.95
    2-ethoxyethyl acetate 75.58
    2-ethylhexyl acetate 33.98
    1,2,4-trichlorobenzene 74.42
    4-methylpyridine 47.8
    dibutyl ether 17.46
    2,6-dimethyl-4-heptanol 6.81
    DEF 54.28
    dimethyl isosorbide 96.11
    tetrachloroethylene 141.36
    eugenol 48.53
    triacetin 89.88
    span 80 40.83
    1,4-butanediol 6.0
    1,1-dichloroethane 65.21
    2-methyl-1-pentanol 12.83
    methyl formate 21.09
    2-methyl-1-butanol 13.14
    n-decane 1.7
    butyronitrile 13.09
    3,7-dimethyl-1-octanol 12.75
    1-chlorooctane 10.5
    1-chlorotetradecane 3.15
    n-nonane 1.43
    undecane 1.07
    tert-butylcyclohexane 2.15
    cyclooctane 1.86
    cyclopentanol 24.67
    tetrahydropyran 46.48
    tert-amyl methyl ether 18.47
    2,5,8-trioxanonane 81.98
    1-hexene 5.2
    2-isopropoxyethanol 25.86
    2,2,2-trifluoroethanol 39.72
    methyl butyrate 48.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction