Isostearamidopropyl Betaine

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  • Identifiers

    CAS number
    63566-37-0

    Molecular formula
    C25H50N2O3

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(=O)[O-]

    Safety labels

  • Odor profile

    Fragrance
    Waxy 36.46%
    Savory 32.34%
    Odorless 32.34%
    Cooling 30.75%
    Fatty 29.95%
    Meaty 29.78%
    Animal 29.57%
    Woody 29.3%
    Fishy 26.04%
    Mint 23.7%

     

    Flavor
    Bland 38.73%
    Mild 30.17%
    Odorless 29.94%
    Faint 22.56%
    Herbal 21.51%
    Slightly waxy 20.81%
    Delicate 20.41%
    Bay oil 19.64%
    Cedarleaf 19.43%
    Yeasty 18.99%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    8.3

    pKa est.
    5.55 (weak acid)

    Molecular weight
    426.7 g/mol

    Flash point

    • -35.66 ˚C est.

  • Synonyms

    • isostearamidopropyl betaine
    • Obazoline isab
    • Mackam isa
    • Schercotaine iab
    • 22W0P0GRB7
    • 63566-37-0
    • UNII-22W0P0GRB7
    • Isostearamidopropyl betaine [INCI]
    • 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-((1-oxoisooctadecyl)amino)-, inner salt
    • RefChem:149981
    • 2-[dimethyl-[3-(16-methylheptadecanoylamino)propyl]azaniumyl]acetate
    • SCHEMBL27915629
    • LMVGXBRDRZOPHA-UHFFFAOYSA-N
    • DTXSID901021230
    • Q27253677
    • (Dimethyl{3-[(16-methylheptadecanoyl)amino]propyl}ammonio)acetate
    • 63566-37-0

  • Applications

    Isostearamidopropyl Betaine is an amphoteric surfactant commonly used in cosmetics and personal care, household cleaning products, industrial cleaners, coatings and inks, and polymer formulation processing, serving as a mild surfactant with good foaming and conditioning properties, an emulsifier, a wetting agent, and a viscosity modifier in certain systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 23.8
    methanol 50.72
    isopropanol 11.19
    water 2.05
    ethyl acetate 16.85
    n-propanol 20.72
    acetone 27.73
    n-butanol 15.3
    acetonitrile 7.43
    DMF 59.42
    toluene 9.58
    isobutanol 15.16
    1,4-dioxane 25.8
    methyl acetate 18.87
    THF 63.34
    2-butanone 29.19
    n-pentanol 13.49
    sec-butanol 14.5
    n-hexane 1.2
    ethylene glycol 7.26
    NMP 183.53
    cyclohexane 3.03
    DMSO 74.05
    n-butyl acetate 19.59
    n-octanol 11.54
    chloroform 93.92
    n-propyl acetate 21.4
    acetic acid 94.91
    dichloromethane 79.81
    cyclohexanone 78.39
    propylene glycol 15.52
    isopropyl acetate 14.48
    DMAc 119.6
    2-ethoxyethanol 40.98
    isopentanol 13.78
    n-heptane 0.87
    ethyl formate 22.14
    1,2-dichloroethane 46.1
    n-hexanol 11.29
    2-methoxyethanol 50.86
    isobutyl acetate 16.43
    tetrachloromethane 20.53
    n-pentyl acetate 31.02
    transcutol 129.37
    n-heptanol 14.46
    ethylbenzene 6.21
    MIBK 16.49
    2-propoxyethanol 38.26
    tert-butanol 13.33
    MTBE 9.45
    2-butoxyethanol 48.96
    propionic acid 39.53
    o-xylene 10.57
    formic acid 60.88
    diethyl ether 6.61
    m-xylene 8.09
    p-xylene 8.35
    chlorobenzene 17.72
    dimethyl carbonate 13.27
    n-octane 0.62
    formamide 66.6
    cyclopentanone 86.25
    2-pentanone 20.81
    anisole 11.93
    cyclopentyl methyl ether 28.59
    gamma-butyrolactone 102.21
    1-methoxy-2-propanol 37.11
    pyridine 35.91
    3-pentanone 19.37
    furfural 90.39
    n-dodecane 0.36
    diethylene glycol 27.41
    diisopropyl ether 3.03
    tert-amyl alcohol 17.98
    acetylacetone 31.43
    n-hexadecane 0.42
    acetophenone 25.65
    methyl propionate 21.76
    isopentyl acetate 21.98
    trichloroethylene 106.59
    n-nonanol 11.45
    cyclohexanol 26.91
    benzyl alcohol 20.11
    2-ethylhexanol 9.33
    isooctanol 13.07
    dipropyl ether 7.55
    1,2-dichlorobenzene 22.33
    ethyl lactate 21.38
    propylene carbonate 58.68
    n-methylformamide 44.34
    2-pentanol 8.78
    n-pentane 0.99
    1-propoxy-2-propanol 29.85
    1-methoxy-2-propyl acetate 32.04
    2-(2-methoxypropoxy) propanol 40.15
    mesitylene 5.5
    ε-caprolactone 82.5
    p-cymene 6.13
    epichlorohydrin 86.45
    1,1,1-trichloroethane 40.17
    2-aminoethanol 20.48
    morpholine-4-carbaldehyde 89.94
    sulfolane 201.15
    2,2,4-trimethylpentane 1.36
    2-methyltetrahydrofuran 41.9
    n-hexyl acetate 28.8
    isooctane 0.58
    2-(2-butoxyethoxy)ethanol 53.01
    sec-butyl acetate 15.31
    tert-butyl acetate 20.16
    decalin 1.74
    glycerin 31.76
    diglyme 95.89
    acrylic acid 41.46
    isopropyl myristate 7.91
    n-butyric acid 47.83
    acetyl acetate 17.69
    di(2-ethylhexyl) phthalate 17.13
    ethyl propionate 16.87
    nitromethane 76.42
    1,2-diethoxyethane 19.58
    benzonitrile 15.93
    trioctyl phosphate 11.36
    1-bromopropane 17.21
    gamma-valerolactone 137.43
    n-decanol 6.78
    triethyl phosphate 16.7
    4-methyl-2-pentanol 7.1
    propionitrile 8.44
    vinylene carbonate 52.1
    1,1,2-trichlorotrifluoroethane 137.58
    DMS 23.66
    cumene 5.56
    2-octanol 8.8
    2-hexanone 20.3
    octyl acetate 12.53
    limonene 8.56
    1,2-dimethoxyethane 40.04
    ethyl orthosilicate 15.79
    tributyl phosphate 13.77
    diacetone alcohol 37.25
    N,N-dimethylaniline 11.85
    acrylonitrile 13.39
    aniline 19.0
    1,3-propanediol 24.63
    bromobenzene 15.31
    dibromomethane 45.46
    1,1,2,2-tetrachloroethane 100.34
    2-methyl-cyclohexyl acetate 25.54
    tetrabutyl urea 19.31
    diisobutyl methanol 5.16
    2-phenylethanol 18.15
    styrene 6.38
    dioctyl adipate 20.14
    dimethyl sulfate 42.04
    ethyl butyrate 18.03
    methyl lactate 25.88
    butyl lactate 39.19
    diethyl carbonate 12.77
    propanediol butyl ether 44.84
    triethyl orthoformate 19.06
    p-tert-butyltoluene 5.61
    methyl 4-tert-butylbenzoate 43.25
    morpholine 46.88
    tert-butylamine 6.9
    n-dodecanol 4.07
    dimethoxymethane 27.12
    ethylene carbonate 40.91
    cyrene 56.17
    2-ethoxyethyl acetate 42.31
    2-ethylhexyl acetate 18.85
    1,2,4-trichlorobenzene 31.61
    4-methylpyridine 27.12
    dibutyl ether 7.58
    2,6-dimethyl-4-heptanol 5.16
    DEF 36.09
    dimethyl isosorbide 65.12
    tetrachloroethylene 82.12
    eugenol 40.46
    triacetin 52.01
    span 80 37.24
    1,4-butanediol 12.49
    1,1-dichloroethane 30.42
    2-methyl-1-pentanol 14.23
    methyl formate 30.92
    2-methyl-1-butanol 16.88
    n-decane 0.83
    butyronitrile 9.3
    3,7-dimethyl-1-octanol 10.2
    1-chlorooctane 5.83
    1-chlorotetradecane 1.52
    n-nonane 0.75
    undecane 0.52
    tert-butylcyclohexane 1.38
    cyclooctane 1.03
    cyclopentanol 30.04
    tetrahydropyran 29.48
    tert-amyl methyl ether 12.66
    2,5,8-trioxanonane 56.28
    1-hexene 4.11
    2-isopropoxyethanol 27.09
    2,2,2-trifluoroethanol 56.99
    methyl butyrate 25.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction