Isopropylamine

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  • Identifiers

    CAS number
    75-31-0

    Molecular formula
    C3H9N

    SMILES
    CC(C)N

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 80.08%
    Cheesy 78.6%
    Ripe 54.69%
    Fermented 27.46%
    Pungent 24.86%
    Sweaty 23.97%
    Oily 23.53%
    Musty 21.79%
    Meaty 21.37%
    Solvent 20.09%

     

    Flavor
    Fishy 57.75%
    Ammoniacal 44.6%
    Ammonia 32.54%
    Meaty 26.21%
    Sulfurous 23.28%
    Onion 22.59%
    Glue 22.55%
    Bloody 21.79%
    Cheesy 20.4%
    Yeasty 19.97%

     

    Odor impact est.
    High

    Odor threshold

    • Odor Threshold Low: 0.21 [mmHg]. Odor Threshold High: 0.7 [mmHg]. Detection odor threshold from AIHA (mean = 0.21 ppm)
    • 0.504 mg/cu m (Odor low) 480 mg/cu m (Odor high)

  • Properties

    XLogP3-AA
    0.1

    pKa est.
    8.91 (weak base)

    Molecular weight
    59.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -150 °F (NTP, 1992)
    • -95.119 °C
    • -95.2 °C
    • -150 °F

    Boiling point

    • 90.3 °F at 760 mmHg (NTP, 1992)
    • 31.8 °C
    • 31.7 °C
    • 91 °F

    Flash point

    • -24.69 ˚C est.
    • -35 °F (NTP, 1992)
    • -26 °C
    • -18 °C (0 °F) (Closed cup)
    • -35 °F (-37 °C) (open cup)
    • -37 °C c.c.
    • -35 °F (open cup)
    • (oc) -35 °F

    Solubility expt.

    • Very soluble (NTP, 1992)
    • In water, 1X10+6 mg/L at 20 °C /miscible/
    • Miscible with water
    • Miscible with ethanol, ether; very soluble in acetone; soluble in benzene, chloroform
    • Solubility in water: miscible
    • Soluble in water
    • Soluble (in ethanol)
    • Miscible

  • Synonyms

    • ISOPROPYLAMINE
    • propan-2-amine
    • 75-31-0
    • 2-Propanamine
    • 2-Aminopropane
    • Monoisopropylamine
    • 2-Propylamine
    • sec-Propylamine
    • 1-Methylethylamine
    • isopropyl amine
    • Propane, 2-amino-
    • Isopropilamina
    • 2-Aminopropan
    • 2-Amino-propaan
    • 2-Amino-propano
    • 2-Propaneamine
    • NSC 62775
    • CCRIS 4318
    • HSDB 804
    • iso-propylamine
    • UNII-P8W26T4MTD
    • EINECS 200-860-9
    • P8W26T4MTD
    • MFCD00008082
    • CHEBI:15739
    • AI3-15636
    • NSC-62775
    • DTXSID2025682
    • FEMA NO. 4238
    • EC 200-860-9
    • 2-Propan-1,1,1,2,3,3,3-d7-amine
    • Isopropilamina [Italian]
    • 2-Propanamine; 2-Aminopropane;
    • Isopropylamin
    • 2-Aminopropan [German]
    • 2-propylamin
    • 2-Amino-propaan [Dutch]
    • 2-Amino-propano [Italian]
    • UN1221
    • isopropylarnine
    • isoproylamine
    • i-propylamine
    • isopropyl-amine
    • i-propyl amine
    • iso- propylamine
    • iso-propyl amine
    • propane-2-amine
    • 2-propyl amine
    • propan-2 -amine
    • propane, 2-amino
    • iso-Propylamine gas
    • iPrNH2
    • (1-methylethyl)amine
    • i-PrNH2
    • Isopropylamine, 97%
    • Isopropylamine, 99%
    • iso-C3H7NH2
    • 2-AMINO-PROPANE
    • ISOPROPYLAMINE [MI]
    • ISOPROPYLAMINE [FHFI]
    • ISOPROPYLAMINE [HSDB]
    • Isopropylamine, >=99.5%
    • CHEMBL117080
    • DTXCID905682
    • WLN: ZY1&1
    • Isopropylamine, >=97.0% (GC)
    • NSC62775
    • STR00028
    • STL194288
    • AKOS000119321
    • UN 1221
    • I0165
    • NS00002224
    • EN300-18989
    • Isopropylamine, anhydrous, analytical standard
    • Isopropylamine, SAJ special grade, >=99.0%
    • C06748
    • Isopropylamine [UN1221] [Flammable liquid]
    • A838376
    • Q420554
    • InChI=1/C3H9N/c1-3(2)4/h3H,4H2,1-2H
    • Isopropylamine (purified by distillation from glass)
    • F2190-0359
    • 200-860-9
    • G4O

  • Applications

    Isopropylamine, CAS 75-31-0, is a primary amine widely used as an industrial building block and intermediate. Real-world applications include: serving as a key intermediate to form isopropylamine salts for herbicides such as 2,4-D (improving solubility and handling); used as a precursor for the synthesis of other amine-containing intermediates in pharmaceuticals, agrochemicals, and specialty chemicals; employed in the production of dyes and pigment intermediates; used as a basis for amine-functional monomers and additives in polymers and coatings, including epoxy and polyurethane systems; and utilized in the manufacture of surfactants and related specialty chemicals through derivatization of the isopropylamine moiety.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 136.95
    methanol 237.26
    isopropanol 92.24
    water 51.82
    ethyl acetate 36.97
    n-propanol 110.61
    acetone 61.73
    n-butanol 93.53
    acetonitrile 46.28
    DMF 94.05
    toluene 10.49
    isobutanol 68.77
    1,4-dioxane 58.74
    methyl acetate 45.46
    THF 99.61
    2-butanone 55.98
    n-pentanol 50.5
    sec-butanol 82.91
    n-hexane 18.26
    ethylene glycol 117.39
    NMP 119.33
    cyclohexane 15.6
    DMSO 70.9
    n-butyl acetate 53.1
    n-octanol 44.6
    chloroform 65.99
    n-propyl acetate 26.23
    acetic acid 199.19
    dichloromethane 35.55
    cyclohexanone 68.5
    propylene glycol 143.09
    isopropyl acetate 23.61
    DMAc 98.93
    2-ethoxyethanol 65.15
    isopentanol 52.24
    n-heptane 30.43
    ethyl formate 35.08
    1,2-dichloroethane 20.92
    n-hexanol 108.82
    2-methoxyethanol 128.81
    isobutyl acetate 21.36
    tetrachloromethane 30.17
    n-pentyl acetate 29.43
    transcutol 110.94
    n-heptanol 56.81
    ethylbenzene 6.22
    MIBK 18.75
    2-propoxyethanol 137.07
    tert-butanol 85.22
    MTBE 41.05
    2-butoxyethanol 83.26
    propionic acid 127.31
    o-xylene 11.09
    formic acid 130.5
    diethyl ether 35.5
    m-xylene 9.29
    p-xylene 10.23
    chlorobenzene 15.46
    dimethyl carbonate 19.76
    n-octane 8.4
    formamide 71.77
    cyclopentanone 90.07
    2-pentanone 35.75
    anisole 18.11
    cyclopentyl methyl ether 47.87
    gamma-butyrolactone 91.61
    1-methoxy-2-propanol 94.44
    pyridine 40.65
    3-pentanone 37.47
    furfural 75.62
    n-dodecane 5.67
    diethylene glycol 123.45
    diisopropyl ether 13.69
    tert-amyl alcohol 76.88
    acetylacetone 31.28
    n-hexadecane 5.62
    acetophenone 21.87
    methyl propionate 40.78
    isopentyl acetate 40.87
    trichloroethylene 41.57
    n-nonanol 40.52
    cyclohexanol 69.71
    benzyl alcohol 25.81
    2-ethylhexanol 60.21
    isooctanol 36.38
    dipropyl ether 53.89
    1,2-dichlorobenzene 15.47
    ethyl lactate 35.48
    propylene carbonate 54.08
    n-methylformamide 75.22
    2-pentanol 54.95
    n-pentane 17.03
    1-propoxy-2-propanol 117.01
    1-methoxy-2-propyl acetate 47.3
    2-(2-methoxypropoxy) propanol 60.75
    mesitylene 6.66
    ε-caprolactone 61.03
    p-cymene 15.49
    epichlorohydrin 45.98
    1,1,1-trichloroethane 31.25
    2-aminoethanol 150.34
    morpholine-4-carbaldehyde 90.63
    sulfolane 103.21
    2,2,4-trimethylpentane 9.68
    2-methyltetrahydrofuran 64.57
    n-hexyl acetate 39.45
    isooctane 5.58
    2-(2-butoxyethoxy)ethanol 80.26
    sec-butyl acetate 18.69
    tert-butyl acetate 25.72
    decalin 6.39
    glycerin 172.51
    diglyme 97.24
    acrylic acid 123.06
    isopropyl myristate 20.0
    n-butyric acid 108.45
    acetyl acetate 28.71
    di(2-ethylhexyl) phthalate 26.75
    ethyl propionate 25.23
    nitromethane 96.86
    1,2-diethoxyethane 33.73
    benzonitrile 23.09
    trioctyl phosphate 22.03
    1-bromopropane 19.36
    gamma-valerolactone 90.86
    n-decanol 31.87
    triethyl phosphate 23.98
    4-methyl-2-pentanol 25.47
    propionitrile 47.22
    vinylene carbonate 44.22
    1,1,2-trichlorotrifluoroethane 97.72
    DMS 27.05
    cumene 6.73
    2-octanol 31.23
    2-hexanone 29.28
    octyl acetate 30.27
    limonene 27.22
    1,2-dimethoxyethane 57.53
    ethyl orthosilicate 25.21
    tributyl phosphate 25.56
    diacetone alcohol 45.33
    N,N-dimethylaniline 16.58
    acrylonitrile 50.0
    aniline 30.9
    1,3-propanediol 117.76
    bromobenzene 10.87
    dibromomethane 27.95
    1,1,2,2-tetrachloroethane 43.99
    2-methyl-cyclohexyl acetate 35.52
    tetrabutyl urea 32.99
    diisobutyl methanol 28.67
    2-phenylethanol 39.36
    styrene 8.04
    dioctyl adipate 28.0
    dimethyl sulfate 29.65
    ethyl butyrate 38.43
    methyl lactate 57.11
    butyl lactate 44.07
    diethyl carbonate 26.24
    propanediol butyl ether 82.95
    triethyl orthoformate 36.18
    p-tert-butyltoluene 16.95
    methyl 4-tert-butylbenzoate 36.98
    morpholine 77.36
    tert-butylamine 59.98
    n-dodecanol 25.76
    dimethoxymethane 40.46
    ethylene carbonate 37.86
    cyrene 49.87
    2-ethoxyethyl acetate 30.41
    2-ethylhexyl acetate 35.6
    1,2,4-trichlorobenzene 22.19
    4-methylpyridine 32.4
    dibutyl ether 28.41
    2,6-dimethyl-4-heptanol 28.67
    DEF 48.49
    dimethyl isosorbide 66.71
    tetrachloroethylene 43.12
    eugenol 43.29
    triacetin 42.55
    span 80 81.63
    1,4-butanediol 59.65
    1,1-dichloroethane 27.23
    2-methyl-1-pentanol 33.43
    methyl formate 48.22
    2-methyl-1-butanol 60.77
    n-decane 8.9
    butyronitrile 40.67
    3,7-dimethyl-1-octanol 35.9
    1-chlorooctane 17.65
    1-chlorotetradecane 8.75
    n-nonane 9.13
    undecane 6.68
    tert-butylcyclohexane 7.77
    cyclooctane 6.64
    cyclopentanol 90.51
    tetrahydropyran 57.29
    tert-amyl methyl ether 37.66
    2,5,8-trioxanonane 75.06
    1-hexene 25.52
    2-isopropoxyethanol 44.85
    2,2,2-trifluoroethanol 84.49
    methyl butyrate 31.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction