Isopropyl Linoleate

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  • Identifiers

    CAS number
    22882-95-7

    Molecular formula
    C21H38O2

    SMILES
    CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(C)C

    Safety labels

  • Odor profile

    Fragrance
    Fatty 79.04%
    Oily 66.55%
    Waxy 51.17%
    Fruity 49.3%
    Dairy 26.58%
    Green 26.27%
    Sweet 24.38%
    Herbal 24.38%
    Creamy 24.23%
    Buttery 23.53%

     

    Flavor
    Faint 25.05%
    Fatty 22.95%
    Waxy 22.06%
    Oily 20.71%
    Delicate 20.31%
    Slightly waxy 20.09%
    Diterpene 19.7%
    Low 19.65%
    Oriental 19.24%
    Bay oil 18.84%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.7

    pKa est.
    7.42 (neutral)

    Molecular weight
    322.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    361°C

    Flash point

    • 172.46 ˚C est.

  • Synonyms

    • Isopropyl linoleate
    • Ceraphyl IPL
    • Isopropyl linolate
    • 22882-95-7
    • Linoleic acid, isopropyl ester
    • 1-Methylethyl-9,12-octadecadienoate
    • 9,12-Octadecadienoic acid (Z,Z)-, 1-methylethyl ester
    • UNII-4MW1E9AT4H
    • EINECS 245-289-6
    • 4MW1E9AT4H
    • BRN 1880297
    • NIKKOL VF-IP
    • 9,12-Octadecadienoic acid, 1-methylethyl ester
    • AEC ISOPROPYL LINOLEATE
    • 9,12-OCTADECADIENOIC ACID (9Z,12Z)-, 1-METHYLETHYL ESTER 9,12-OCTADECADIENOIC ACID (9Z,12Z)-, 1-METHYLETHYL ESTER
    • RefChem:149826
    • ISOPROPYL LINOLEATE [INCI]
    • 245-289-6
    • XEIOPEQGDSYOIH-MURFETPASA-N
    • Linoleic Acid Isopropyl Ester
    • Isopropyl (9Z,12Z)-octadeca-9,12-dienoate
    • MFCD00053809
    • ISOPROPYLLINOLEATE
    • propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate
    • SCHEMBL43113
    • orb2939583
    • 60% GC
    • HY-W127420
    • CS-0185654
    • L0139
    • NS00013787
    • Isopropyl (9Z,12Z)-9,12-octadecadienoate #
    • Q27260149
    • 22882-95-7

  • Applications

    Isopropyl Linoleate is a fatty acid ester commonly used in cosmetics and personal care as an emollient and skin-conditioning agent, contributing slip, moisturization, and a soft feel in lotions, creams, and makeup formulations. It also serves as a solvent or carrier for fragrance ingredients, aiding solubilization and distribution of aroma compounds in formulations. In polymer and coating applications, it can function as a plasticizer or processing aid to improve flexibility and flow of resins and coatings. It is used in household and cleaning products as a solvent or solubilizer for active ingredients and fragrance oils, helping formulate stable, homogeneous products. In pharmaceutical topical formulations, it can act as an inert solvent or excipient within regulated limits, enabling formulation of creams, gels, or ointments. Use is subject to local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 531.25
    methanol 386.36
    isopropanol 607.3
    water 0.03
    ethyl acetate 1416.93
    n-propanol 611.94
    acetone 1305.82
    n-butanol 723.16
    acetonitrile 414.12
    DMF 1030.88
    toluene 595.38
    isobutanol 579.88
    1,4-dioxane 1328.07
    methyl acetate 784.18
    THF 2753.84
    2-butanone 1314.29
    n-pentanol 528.82
    sec-butanol 727.35
    n-hexane 320.06
    ethylene glycol 15.21
    NMP 1654.78
    cyclohexane 957.63
    DMSO 1192.75
    n-butyl acetate 1189.15
    n-octanol 305.75
    chloroform 2558.52
    n-propyl acetate 1293.68
    acetic acid 372.76
    dichloromethane 2792.99
    cyclohexanone 2906.36
    propylene glycol 64.85
    isopropyl acetate 1154.64
    DMAc 1629.28
    2-ethoxyethanol 606.79
    isopentanol 803.31
    n-heptane 182.91
    ethyl formate 471.18
    1,2-dichloroethane 2010.52
    n-hexanol 464.01
    2-methoxyethanol 662.79
    isobutyl acetate 849.83
    tetrachloromethane 530.3
    n-pentyl acetate 1153.26
    transcutol 2588.47
    n-heptanol 285.49
    ethylbenzene 403.38
    MIBK 1119.57
    2-propoxyethanol 710.7
    tert-butanol 833.94
    MTBE 1496.93
    2-butoxyethanol 549.72
    propionic acid 382.44
    o-xylene 452.64
    formic acid 50.31
    diethyl ether 1546.38
    m-xylene 429.85
    p-xylene 549.96
    chlorobenzene 825.04
    dimethyl carbonate 204.49
    n-octane 69.8
    formamide 101.83
    cyclopentanone 2212.18
    2-pentanone 1499.81
    anisole 692.38
    cyclopentyl methyl ether 1865.08
    gamma-butyrolactone 1711.14
    1-methoxy-2-propanol 733.6
    pyridine 1209.11
    3-pentanone 1058.61
    furfural 1030.81
    n-dodecane 38.9
    diethylene glycol 228.35
    diisopropyl ether 536.78
    tert-amyl alcohol 896.58
    acetylacetone 1269.24
    n-hexadecane 47.94
    acetophenone 708.59
    methyl propionate 834.38
    isopentyl acetate 1166.27
    trichloroethylene 2698.62
    n-nonanol 292.91
    cyclohexanol 1121.36
    benzyl alcohol 399.1
    2-ethylhexanol 449.33
    isooctanol 301.92
    dipropyl ether 946.91
    1,2-dichlorobenzene 833.55
    ethyl lactate 314.98
    propylene carbonate 969.52
    n-methylformamide 324.23
    2-pentanol 636.44
    n-pentane 221.51
    1-propoxy-2-propanol 705.2
    1-methoxy-2-propyl acetate 935.01
    2-(2-methoxypropoxy) propanol 533.29
    mesitylene 318.85
    ε-caprolactone 2033.64
    p-cymene 255.47
    epichlorohydrin 2129.17
    1,1,1-trichloroethane 1931.44
    2-aminoethanol 93.39
    morpholine-4-carbaldehyde 1246.91
    sulfolane 2136.46
    2,2,4-trimethylpentane 137.3
    2-methyltetrahydrofuran 2602.4
    n-hexyl acetate 1221.77
    isooctane 83.38
    2-(2-butoxyethoxy)ethanol 748.67
    sec-butyl acetate 976.44
    tert-butyl acetate 1322.76
    decalin 271.97
    glycerin 83.73
    diglyme 1536.84
    acrylic acid 203.3
    isopropyl myristate 397.3
    n-butyric acid 1088.35
    acetyl acetate 637.87
    di(2-ethylhexyl) phthalate 291.1
    ethyl propionate 1037.35
    nitromethane 776.28
    1,2-diethoxyethane 1301.62
    benzonitrile 568.69
    trioctyl phosphate 221.18
    1-bromopropane 1571.28
    gamma-valerolactone 2330.77
    n-decanol 189.38
    triethyl phosphate 391.13
    4-methyl-2-pentanol 388.03
    propionitrile 531.87
    vinylene carbonate 685.97
    1,1,2-trichlorotrifluoroethane 966.38
    DMS 575.74
    cumene 282.85
    2-octanol 272.64
    2-hexanone 1218.21
    octyl acetate 481.34
    limonene 578.13
    1,2-dimethoxyethane 1512.66
    ethyl orthosilicate 421.67
    tributyl phosphate 310.48
    diacetone alcohol 943.01
    N,N-dimethylaniline 488.28
    acrylonitrile 417.62
    aniline 527.2
    1,3-propanediol 250.87
    bromobenzene 999.17
    dibromomethane 1986.77
    1,1,2,2-tetrachloroethane 2587.37
    2-methyl-cyclohexyl acetate 800.57
    tetrabutyl urea 459.71
    diisobutyl methanol 296.89
    2-phenylethanol 399.87
    styrene 486.65
    dioctyl adipate 587.64
    dimethyl sulfate 388.07
    ethyl butyrate 1007.97
    methyl lactate 247.61
    butyl lactate 600.94
    diethyl carbonate 504.74
    propanediol butyl ether 427.41
    triethyl orthoformate 702.58
    p-tert-butyltoluene 235.95
    methyl 4-tert-butylbenzoate 651.98
    morpholine 1949.1
    tert-butylamine 619.64
    n-dodecanol 138.89
    dimethoxymethane 823.22
    ethylene carbonate 718.06
    cyrene 491.51
    2-ethoxyethyl acetate 1046.78
    2-ethylhexyl acetate 992.53
    1,2,4-trichlorobenzene 918.33
    4-methylpyridine 1367.82
    dibutyl ether 1017.43
    2,6-dimethyl-4-heptanol 296.89
    DEF 1497.04
    dimethyl isosorbide 1057.07
    tetrachloroethylene 1614.74
    eugenol 482.32
    triacetin 955.22
    span 80 567.14
    1,4-butanediol 99.39
    1,1-dichloroethane 1926.46
    2-methyl-1-pentanol 586.17
    methyl formate 211.03
    2-methyl-1-butanol 739.92
    n-decane 89.53
    butyronitrile 820.28
    3,7-dimethyl-1-octanol 362.89
    1-chlorooctane 416.67
    1-chlorotetradecane 127.88
    n-nonane 92.44
    undecane 54.61
    tert-butylcyclohexane 185.68
    cyclooctane 207.33
    cyclopentanol 922.81
    tetrahydropyran 2907.59
    tert-amyl methyl ether 1200.77
    2,5,8-trioxanonane 906.3
    1-hexene 764.42
    2-isopropoxyethanol 574.92
    2,2,2-trifluoroethanol 113.0
    methyl butyrate 1439.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction