Isopropyl anthranilate

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  • Identifiers

    CAS number
    18189-02-1

    Molecular formula
    C10H13NO2

    SMILES
    CC(C)OC(=O)C1=CC=CC=C1N

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 73.17%
    Grape 72.31%
    Fruity 54.79%
    Neroli 47.44%
    Sweet 43.83%
    Orange 37.55%
    Animal 32.34%
    Honey 30.66%
    Berry 28.86%
    Powdery 26.95%

     

    Flavor
    Fruity 80.95%
    Sweet 65.94%
    Floral 53.47%
    Grape 48.14%
    Bitter 42.5%
    Powdery 35.38%
    Berry 32.17%
    Mild 26.12%
    Strawberry 25.85%
    Herbal 25.82%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.7

    pKa est.
    5.71 (weak acid)

    Molecular weight
    179.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    275°C

    Flash point

    • 135.05 ˚C est.

  • Synonyms

    • Isopropyl anthranilate
    • Isopropyl 2-aminobenzoate
    • 18189-02-1
    • propan-2-yl 2-aminobenzoate
    • Benzoic acid, 2-amino-, 1-methylethyl ester
    • Anthranilic acid, isopropyl ester
    • HMH3887MNJ
    • EINECS 242-074-9
    • AI3-02577
    • DTXSID9066334
    • 2-AMINOBENZOIC ACID ISOPROPYL ESTER
    • MFCD00060604
    • iso-propyl anthranilate
    • Isopropyl 2-amino-benzoate
    • UNII-HMH3887MNJ
    • Isopropyl 2-aminobenzoate #
    • SCHEMBL3507300
    • DTXCID6035782
    • AKOS009165959
    • DS-1584
    • FI140747
    • DB-044447
    • NS00025984
    • 242-074-9

  • Applications

    Isopropyl anthranilate (CAS 18189-02-1) is primarily used as a fragrance ingredient and fixative in perfumery and cosmetics, delivering fruity, grape-like notes. It is commonly employed as an odorant in consumer products and can be formulated into scented household items such as air fresheners and cleaners, as well as personal care formulations. It also serves as a synthetic intermediate for developing specialized aroma compounds. Depending on local regulations and formulation limits, its use may extend to other permitted applications in flavor or consumer product sectors.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 278.77
    methanol 399.56
    isopropanol 216.3
    water 3.48
    ethyl acetate 84.87
    n-propanol 204.26
    acetone 248.2
    n-butanol 175.85
    acetonitrile 174.86
    DMF 760.89
    toluene 30.04
    isobutanol 136.07
    1,4-dioxane 285.84
    methyl acetate 109.73
    THF 518.88
    2-butanone 117.66
    n-pentanol 121.25
    sec-butanol 150.24
    n-hexane 5.44
    ethylene glycol 120.12
    NMP 447.96
    cyclohexane 12.72
    DMSO 621.95
    n-butyl acetate 63.81
    n-octanol 67.74
    chloroform 412.09
    n-propyl acetate 59.27
    acetic acid 417.87
    dichloromethane 309.83
    cyclohexanone 241.63
    propylene glycol 221.55
    isopropyl acetate 49.84
    DMAc 341.28
    2-ethoxyethanol 137.22
    isopentanol 111.56
    n-heptane 4.47
    ethyl formate 131.8
    1,2-dichloroethane 161.66
    n-hexanol 113.91
    2-methoxyethanol 344.72
    isobutyl acetate 40.5
    tetrachloromethane 30.13
    n-pentyl acetate 44.68
    transcutol 225.34
    n-heptanol 55.98
    ethylbenzene 23.4
    MIBK 59.85
    2-propoxyethanol 182.91
    tert-butanol 196.63
    MTBE 57.1
    2-butoxyethanol 93.32
    propionic acid 202.24
    o-xylene 27.77
    formic acid 161.8
    diethyl ether 54.18
    m-xylene 27.18
    p-xylene 34.8
    chlorobenzene 92.22
    dimethyl carbonate 74.38
    n-octane 2.68
    formamide 190.43
    cyclopentanone 348.08
    2-pentanone 97.74
    anisole 71.7
    cyclopentyl methyl ether 121.19
    gamma-butyrolactone 410.24
    1-methoxy-2-propanol 243.01
    pyridine 190.17
    3-pentanone 63.57
    furfural 342.42
    n-dodecane 3.69
    diethylene glycol 189.34
    diisopropyl ether 14.13
    tert-amyl alcohol 120.71
    acetylacetone 126.76
    n-hexadecane 4.16
    acetophenone 81.41
    methyl propionate 92.56
    isopentyl acetate 59.22
    trichloroethylene 354.07
    n-nonanol 55.32
    cyclohexanol 148.25
    benzyl alcohol 93.44
    2-ethylhexanol 51.43
    isooctanol 41.78
    dipropyl ether 35.45
    1,2-dichlorobenzene 85.65
    ethyl lactate 71.71
    propylene carbonate 237.99
    n-methylformamide 257.12
    2-pentanol 89.05
    n-pentane 5.63
    1-propoxy-2-propanol 115.15
    1-methoxy-2-propyl acetate 79.54
    2-(2-methoxypropoxy) propanol 91.54
    mesitylene 19.32
    ε-caprolactone 195.53
    p-cymene 20.29
    epichlorohydrin 331.15
    1,1,1-trichloroethane 123.89
    2-aminoethanol 212.73
    morpholine-4-carbaldehyde 300.03
    sulfolane 514.91
    2,2,4-trimethylpentane 4.29
    2-methyltetrahydrofuran 210.88
    n-hexyl acetate 77.87
    isooctane 3.42
    2-(2-butoxyethoxy)ethanol 129.3
    sec-butyl acetate 34.94
    tert-butyl acetate 56.37
    decalin 7.12
    glycerin 260.34
    diglyme 189.81
    acrylic acid 210.76
    isopropyl myristate 32.33
    n-butyric acid 234.48
    acetyl acetate 79.4
    di(2-ethylhexyl) phthalate 51.41
    ethyl propionate 57.01
    nitromethane 410.2
    1,2-diethoxyethane 58.05
    benzonitrile 112.31
    trioctyl phosphate 38.58
    1-bromopropane 70.01
    gamma-valerolactone 358.18
    n-decanol 43.12
    triethyl phosphate 39.32
    4-methyl-2-pentanol 46.12
    propionitrile 122.49
    vinylene carbonate 214.51
    1,1,2-trichlorotrifluoroethane 289.47
    DMS 71.24
    cumene 20.45
    2-octanol 40.66
    2-hexanone 68.93
    octyl acetate 48.18
    limonene 29.38
    1,2-dimethoxyethane 215.87
    ethyl orthosilicate 34.47
    tributyl phosphate 40.83
    diacetone alcohol 115.72
    N,N-dimethylaniline 53.72
    acrylonitrile 164.6
    aniline 91.51
    1,3-propanediol 236.14
    bromobenzene 73.51
    dibromomethane 184.84
    1,1,2,2-tetrachloroethane 297.14
    2-methyl-cyclohexyl acetate 59.0
    tetrabutyl urea 57.83
    diisobutyl methanol 30.2
    2-phenylethanol 85.56
    styrene 30.7
    dioctyl adipate 57.66
    dimethyl sulfate 138.06
    ethyl butyrate 52.47
    methyl lactate 121.0
    butyl lactate 65.88
    diethyl carbonate 48.78
    propanediol butyl ether 124.57
    triethyl orthoformate 43.01
    p-tert-butyltoluene 20.81
    methyl 4-tert-butylbenzoate 82.85
    morpholine 321.56
    tert-butylamine 88.02
    n-dodecanol 33.4
    dimethoxymethane 213.71
    ethylene carbonate 164.51
    cyrene 128.61
    2-ethoxyethyl acetate 57.62
    2-ethylhexyl acetate 43.85
    1,2,4-trichlorobenzene 111.81
    4-methylpyridine 153.01
    dibutyl ether 36.5
    2,6-dimethyl-4-heptanol 30.2
    DEF 129.0
    dimethyl isosorbide 151.85
    tetrachloroethylene 151.32
    eugenol 92.9
    triacetin 80.11
    span 80 103.68
    1,4-butanediol 103.06
    1,1-dichloroethane 156.45
    2-methyl-1-pentanol 90.9
    methyl formate 209.63
    2-methyl-1-butanol 107.54
    n-decane 5.34
    butyronitrile 137.95
    3,7-dimethyl-1-octanol 48.67
    1-chlorooctane 28.32
    1-chlorotetradecane 12.15
    n-nonane 4.73
    undecane 4.36
    tert-butylcyclohexane 6.52
    cyclooctane 3.32
    cyclopentanol 224.48
    tetrahydropyran 210.34
    tert-amyl methyl ether 45.47
    2,5,8-trioxanonane 153.28
    1-hexene 26.02
    2-isopropoxyethanol 83.71
    2,2,2-trifluoroethanol 130.79
    methyl butyrate 88.55

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction