Isopropyl Alcohol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    67-63-0

    Molecular formula
    C3H8O

    SMILES
    CC(C)O

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

    Retention indicies (RI)

    • DB5: 500.0
    • Carbowax: 958.67

  • Odor profile

    Alcoholic 70.64%
    Ethereal 69.18%
    Solvent 63.04%
    Fermented 57.09%
    Woody 50.05%
    Musty 49.16%
    Sweet 38.99%
    Pungent 38.22%
    Camphoreous 38.22%
    Winey 36.43%

    Scent© AI

    Odor threshold

    • Odor Threshold Low: 1.0 [mmHg]. Odor Threshold High: 610.0 [mmHg]. Detection odor threshold from AIHA (mean = 43 ppm)
    • 90 mg/cu m
    • ... MIN CONCN WITH IDENTIFIABLE ODOR ... IS 200 PPM.
    • Odor threshold 7.84 mg/cu m (low) 490 mg/cu m (high).
    • ... Air odor threshold for isopropanol has been reported as 22 ppm and 40 ppm.

  • Properties

    XLogP3-AA
    0.3

    pKa est.
    10.44 (weak base)

    Molecular weight
    60.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -127.3 °F (NTP, 1992)
    • -89.5 °C
    • -87.9 °C
    • -90 °C
    • -127 °F

    Boiling point

    • 180.5 °F at 760 mmHg (NTP, 1992)
    • 82.3 °C
    • 82.3 °C at 760 mm Hg
    • 83 °C
    • 181 °F

    Flash point est.
    3.28 ˚C

    Flash point expt.

    • 53 °F (NTP, 1992)
    • 12 °C
    • 12 °C, 53 °F (Closed cup)
    • 75 °F (open cup) /91% isopropanol/
    • 11.7 °C c.c.
    • 53 °F

    Solubility expt.

    • greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)
    • 1000000 mg/L (at 25 °C)
    • Miscible with alcohol, ether, chloroform; insoluble in salt solution
    • Very soluble in benzene
    • Miscible with most organic solvents
    • > 10% in alcohol, ether, and acetone
    • In water, infinitely soluble at 25 °C
    • 1000.0 mg/mL
    • Solubility in water: miscible
    • miscible with water, alcohol, ether and organic solvents
    • Miscible

  • Synonyms

    • isopropanol
    • Isopropyl alcohol
    • 2-Propanol
    • Propan-2-ol
    • 67-63-0
    • 2-Hydroxypropane
    • Alkolave
    • Avantine
    • Hartosol
    • Dimethylcarbinol
    • i-Propanol
    • sec-Propyl alcohol
    • Takineocol
    • Alcojel
    • Avantin
    • Petrohol
    • 1-Methylethanol
    • 2-Propyl alcohol
    • Isohol
    • Lavacol
    • Lutosol
    • Propol
    • Alcosolve 2
    • Imsol A
    • Alcosolve
    • Arquad DMCB
    • Spectrar
    • 1-Methylethyl alcohol
    • Alcolo
    • i-Propylalkohol
    • Combi-schutz
    • n-Propan-2-ol
    • i-Propyl alcohol
    • Iso-propylalkohol
    • Isopropyl alcohol, rubbing
    • ISO-PROPANOL
    • Alcool isopropilico
    • Alcool isopropylique
    • Visco 1152
    • sec-Propanol
    • Sterisol hand disinfectant
    • Iso-propyl alcohol
    • i-Propanol [German]
    • iso-propylalcohol
    • Alcohol,isopropyl
    • FEMA No. 2929
    • FEMA Number 2929
    • i-Propylalkohol [German]
    • Alcohol, Isopropyl
    • Iso-propylalkohol [German]
    • Alcool isopropilico [Italian]
    • Alcool isopropylique [French]
    • CCRIS 2308
    • HSDB 116
    • Isopropylalkohol
    • isopropy alcohol
    • 2-propanolum
    • propanol-2
    • EINECS 200-661-7
    • NSC 135801
    • NSC-135801
    • BRN 0635639
    • ZURAGARD
    • DTXSID7020762
    • UNII-ND2M416302
    • CHEBI:17824
    • AI3-01636
    • Isopropyl alcohol (USP)
    • Isopropyl alcohol [USP]
    • MFCD00011674
    • ND2M416302
    • IPS 1
    • DTXCID50762
    • EC 200-661-7
    • 4-01-00-01461 (Beilstein Handbook Reference)
    • NSC135801
    • ISOPROPYL ALCOHOL (ISOPROPANOL)
    • 2-Propanol, anhydrous
    • NCGC00090917-01
    • Rubbing alcohol
    • DURAPREP COMPONENT ISOPROPYL ALCOHOL
    • SOLUPREP COMPONENT ISOPROPYL ALCOHOL
    • CHLORAPREP COMPONENT ISOPROPYL ALCOHOL
    • iPrOH
    • 2-PROPANOL (USP-RS)
    • 2-PROPANOL [USP-RS]
    • ISOPROPYL ALCOHOL (II)
    • ISOPROPYL ALCOHOL [II]
    • ISOPROPYL ALCOHOL (IARC)
    • ISOPROPYL ALCOHOL [IARC]
    • 2-Propanol, USP, 99.0%
    • Caswell No. 507
    • ISOPROPYL ALCOHOL (MART.)
    • ISOPROPYL ALCOHOL [MART.]
    • isopropylalcohol
    • ISOPROPYL ALCOHOL(2-D)
    • 2 Propanol
    • 2-Propanol, ACS reagent, >=99.5%
    • CAS-67-63-0
    • ISOPROPYL ALCOHOL (EP MONOGRAPH)
    • ISOPROPYL ALCOHOL [EP MONOGRAPH]
    • ACETONE IMPURITY B (EP IMPURITY)
    • ACETONE IMPURITY B [EP IMPURITY]
    • ISOPROPYL ALCOHOL (USP MONOGRAPH)
    • ISOPROPYL ALCOHOL [USP MONOGRAPH]
    • Isopropyl alcohol; Propan-2-ol; 2-Propanol
    • UN1219
    • ISOPROPYL ALCOHOL(1,1,1,3,3,3-D6)
    • isopropyl
    • ISOPROPYL ALCOHOL(1,1,1,2,3,3,3-D7)
    • isoproylalcohol
    • sparkle
    • Stanitizer
    • Umbiliclean
    • Aplicare
    • Cornells
    • Everclear
    • Handwipe
    • Hanitize
    • Medpride
    • Purifie
    • Sanacare
    • Septinol
    • Unichem
    • Virahol
    • i-propylalcohol
    • Isopro
    • Lavaco

  • Applications

    Isopropyl alcohol (IPA, isopropanol, CAS 67-63-0) is a volatile organic solvent with broad applications in healthcare, industry and everyday life: as a disinfectant it is formulated at 70-90 % to sanitize hands, wounds and medical surfaces; as a solvent it dissolves resins, greases, inks and paints for printing, coatings, adhesives and cleaners; its fast evaporation and residue-free nature make it ideal for cleaning electronic components, screens and lenses; in cosmetics, perfumes and hair sprays it acts as a fragrance carrier and antimicrobial agent; in pharmaceuticals it is used to precipitate and purify antibiotics and hormones; in fuels it serves as a water-drying additive and antifreeze for aviation fuel systems; IPA also functions as a reaction medium, extraction solvent, freezing-point depressant and defoamer in various manufacturing processes.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 506.01
    methanol 803.54
    isopropanol 390.98
    water 224.53
    ethyl acetate 81.71
    n-propanol 379.59
    acetone 175.54
    n-butanol 312.27
    acetonitrile 130.86
    DMF 282.4
    toluene 21.31
    isobutanol 237.3
    1,4-dioxane 190.66
    methyl acetate 113.27
    THF 240.81
    2-butanone 133.02
    n-pentanol 161.96
    sec-butanol 300.7
    n-hexane 65.69
    ethylene glycol 461.01
    NMP 246.79
    cyclohexane 50.53
    DMSO 179.18
    n-butyl acetate 81.16
    n-octanol 136.41
    chloroform 182.81
    n-propyl acetate 54.93
    acetic acid 514.17
    dichloromethane 107.35
    cyclohexanone 136.68
    propylene glycol 523.8
    isopropyl acetate 50.29
    DMAc 249.3
    2-ethoxyethanol 215.85
    isopentanol 179.77
    n-heptane 72.11
    ethyl formate 77.26
    1,2-dichloroethane 59.89
    n-hexanol 259.26
    2-methoxyethanol 425.37
    isobutyl acetate 40.85
    tetrachloromethane 69.21
    n-pentyl acetate 62.92
    transcutol 363.51
    n-heptanol 137.04
    ethylbenzene 16.71
    MIBK 46.4
    2-propoxyethanol 329.12
    tert-butanol 367.48
    MTBE 130.51
    2-butoxyethanol 202.26
    propionic acid 340.34
    o-xylene 25.79
    formic acid 364.35
    diethyl ether 111.29
    m-xylene 20.08
    p-xylene 25.18
    chlorobenzene 30.1
    dimethyl carbonate 42.5
    n-octane 21.75
    formamide 208.7
    cyclopentanone 171.2
    2-pentanone 84.53
    anisole 46.4
    cyclopentyl methyl ether 105.39
    gamma-butyrolactone 173.51
    1-methoxy-2-propanol 294.87
    pyridine 90.71
    3-pentanone 81.46
    furfural 138.78
    n-dodecane 16.55
    diethylene glycol 331.15
    diisopropyl ether 38.29
    tert-amyl alcohol 272.88
    acetylacetone 66.03
    n-hexadecane 16.15
    acetophenone 45.98
    methyl propionate 89.93
    isopentyl acetate 64.96
    trichloroethylene 95.03
    n-nonanol 116.48
    cyclohexanol 195.3
    benzyl alcohol 66.87
    2-ethylhexanol 125.69
    isooctanol 90.13
    dipropyl ether 111.86
    1,2-dichlorobenzene 31.67
    ethyl lactate 76.59
    propylene carbonate 92.4
    n-methylformamide 207.28
    2-pentanol 192.04
    n-pentane 64.88
    1-propoxy-2-propanol 242.82
    1-methoxy-2-propyl acetate 79.92
    2-(2-methoxypropoxy) propanol 152.91
    mesitylene 15.65
    ε-caprolactone 124.06
    p-cymene 29.34
    epichlorohydrin 111.14
    1,1,1-trichloroethane 75.76
    2-aminoethanol 555.73
    morpholine-4-carbaldehyde 229.5
    sulfolane 182.33
    2,2,4-trimethylpentane 27.57
    2-methyltetrahydrofuran 159.14
    n-hexyl acetate 100.83
    isooctane 17.05
    2-(2-butoxyethoxy)ethanol 216.95
    sec-butyl acetate 38.73
    tert-butyl acetate 56.51
    decalin 18.14
    glycerin 576.76
    diglyme 258.86
    acrylic acid 310.46
    isopropyl myristate 46.92
    n-butyric acid 241.7
    acetyl acetate 52.4
    di(2-ethylhexyl) phthalate 53.72
    ethyl propionate 54.86
    nitromethane 234.55
    1,2-diethoxyethane 87.94
    benzonitrile 49.57
    trioctyl phosphate 46.48
    1-bromopropane 53.23
    gamma-valerolactone 188.44
    n-decanol 88.37
    triethyl phosphate 40.1
    4-methyl-2-pentanol 86.91
    propionitrile 120.72
    vinylene carbonate 79.21
    1,1,2-trichlorotrifluoroethane 212.57
    DMS 60.63
    cumene 17.58
    2-octanol 83.37
    2-hexanone 68.3
    octyl acetate 67.01
    limonene 51.26
    1,2-dimethoxyethane 186.13
    ethyl orthosilicate 42.76
    tributyl phosphate 51.17
    diacetone alcohol 112.63
    N,N-dimethylaniline 45.14
    acrylonitrile 123.21
    aniline 72.7
    1,3-propanediol 405.51
    bromobenzene 19.76
    dibromomethane 79.0
    1,1,2,2-tetrachloroethane 107.04
    2-methyl-cyclohexyl acetate 64.75
    tetrabutyl urea 65.37
    diisobutyl methanol 64.31
    2-phenylethanol 81.31
    styrene 19.9
    dioctyl adipate 64.73
    dimethyl sulfate 53.9
    ethyl butyrate 62.25
    methyl lactate 123.03
    butyl lactate 91.59
    diethyl carbonate 43.37
    propanediol butyl ether 237.38
    triethyl orthoformate 58.23
    p-tert-butyltoluene 31.44
    methyl 4-tert-butylbenzoate 79.23
    morpholine 240.3
    tert-butylamine 261.72
    n-dodecanol 70.79
    dimethoxymethane 125.39
    ethylene carbonate 69.86
    cyrene 106.72
    2-ethoxyethyl acetate 69.67
    2-ethylhexyl acetate 55.84
    1,2,4-trichlorobenzene 44.34
    4-methylpyridine 70.6
    dibutyl ether 80.04
    2,6-dimethyl-4-heptanol 64.31
    DEF 114.82
    dimethyl isosorbide 142.23
    tetrachloroethylene 102.27
    eugenol 96.09
    triacetin 91.15
    span 80 189.25
    1,4-butanediol 202.21
    1,1-dichloroethane 79.77
    2-methyl-1-pentanol 105.42
    methyl formate 123.24
    2-methyl-1-butanol 191.83
    n-decane 25.68
    butyronitrile 100.13
    3,7-dimethyl-1-octanol 99.78
    1-chlorooctane 49.42
    1-chlorotetradecane 25.1
    n-nonane 26.67
    undecane 19.49
    tert-butylcyclohexane 22.4
    cyclooctane 19.48
    cyclopentanol 245.92
    tetrahydropyran 165.15
    tert-amyl methyl ether 109.63
    2,5,8-trioxanonane 201.38
    1-hexene 86.32
    2-isopropoxyethanol 143.24
    2,2,2-trifluoroethanol 216.72
    methyl butyrate 67.66

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Fagraea berteriana flower Fagraea berteriana A. Gray ex Benth., fam. Potaliaceae 0.67%