Isomerase, glucose

Overview IFRA Request a quote

  • Identifiers

    CAS number
    9055-00-9

    Molecular formula
    C17H17ClN2O3S

    SMILES
    C1CN(CCN1C(=O)C2=CC=CC=C2Cl)S(=O)(=O)C3=CC=CC=C3

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 67.06%
    Bitter 24.65%
    Cooked 22.31%
    Savory 18.96%
    Burnt 18.18%
    Roasted 16.71%
    Grape 16.23%
    Nutty 15.96%
    Popcorn 15.93%
    Pungent 15.4%

     

    Flavor
    Bitter 89.33%
    Odorless 27.91%
    Nitrile 19.99%
    Very strong 18.74%
    Indole 18.37%
    Bland 18.34%
    Bread crust 18.33%
    Taco 18.24%
    Cedarleaf 18.01%
    Sweet-like 17.71%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    2.6

    pKa est.
    4.45 (weak acid)

    Molecular weight
    364.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    585°C

    Flash point

    • 261.49 ˚C est.

  • Synonyms

    • Glucose isomerase from streptomyces rubiginosus
    • 1-(benzenesulfonyl)-4-[(2-chlorophenyl)carbonyl]piperazine
    • Isomerase, glucose
    • 1-(benzenesulfonyl)-4-((2-chlorophenyl)carbonyl)piperazine
    • RefChem:791900
    • 232-944-6
    • Isomerase,glucose
    • 9055-00-9
    • [4-(benzenesulfonyl)piperazin-1-yl]-(2-chlorophenyl)methanone
    • (2-chlorophenyl)[4-(phenylsulfonyl)piperazin-1-yl]methanone
    • Oprea1_248066
    • Oprea1_582116
    • SCHEMBL10722342
    • CHEBI:230629
    • WNQJZQMIEZWFIN-UHFFFAOYSA-N
    • STK147352
    • AKOS000551424
    • ST45063596
    • 2-chlorophenyl 4-(phenylsulfonyl)piperazinyl ketone
    • (2-CHLOROPHENYL)[4-(PHENYLSULFONYL)PIPERAZINO]METHANONE
    • [4-(benzenesulonyl)piperazin-1-yl]-(2-chlorophenyl)methanone
    • 9055-00-9

  • Applications

    Isomerase, glucose (CAS 9055-00-9) is a biocatalyst primarily employed in food processing to isomerize glucose to fructose for high-fructose syrups. In industrial manufacturing, it is used as an immobilized enzyme to enable scalable sugar isomerization and process control. It is also evaluated for the selective production of rare sugars and specialty chemicals for pharmaceutical or chemical applications. In research and development, it serves as a model enzyme for carbohydrate isomerization and for optimizing biocatalytic process conditions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.15
    methanol 4.09
    isopropanol 2.53
    water 0.03
    ethyl acetate 11.49
    n-propanol 3.79
    acetone 15.74
    n-butanol 3.53
    acetonitrile 12.92
    DMF 50.13
    toluene 4.08
    isobutanol 2.21
    1,4-dioxane 14.98
    methyl acetate 12.58
    THF 21.37
    2-butanone 24.94
    n-pentanol 3.88
    sec-butanol 3.96
    n-hexane 0.01
    ethylene glycol 1.34
    NMP 34.16
    cyclohexane 0.12
    DMSO 21.12
    n-butyl acetate 9.11
    n-octanol 4.64
    chloroform 29.69
    n-propyl acetate 9.12
    acetic acid 8.76
    dichloromethane 28.27
    cyclohexanone 42.85
    propylene glycol 2.25
    isopropyl acetate 7.1
    DMAc 73.83
    2-ethoxyethanol 14.94
    isopentanol 3.1
    n-heptane 0.05
    ethyl formate 16.14
    1,2-dichloroethane 14.61
    n-hexanol 3.53
    2-methoxyethanol 18.78
    isobutyl acetate 4.19
    tetrachloromethane 0.97
    n-pentyl acetate 13.27
    transcutol 32.17
    n-heptanol 4.69
    ethylbenzene 1.81
    MIBK 7.18
    2-propoxyethanol 16.1
    tert-butanol 2.17
    MTBE 1.61
    2-butoxyethanol 14.52
    propionic acid 7.09
    o-xylene 2.75
    formic acid 7.58
    diethyl ether 2.06
    m-xylene 1.94
    p-xylene 2.56
    chlorobenzene 10.67
    dimethyl carbonate 8.23
    n-octane 0.07
    formamide 18.09
    cyclopentanone 38.86
    2-pentanone 13.81
    anisole 7.69
    cyclopentyl methyl ether 3.87
    gamma-butyrolactone 35.88
    1-methoxy-2-propanol 13.61
    pyridine 38.02
    3-pentanone 10.99
    furfural 53.84
    n-dodecane 0.15
    diethylene glycol 13.03
    diisopropyl ether 0.42
    tert-amyl alcohol 3.03
    acetylacetone 19.91
    n-hexadecane 0.18
    acetophenone 17.22
    methyl propionate 11.48
    isopentyl acetate 7.08
    trichloroethylene 45.88
    n-nonanol 5.33
    cyclohexanol 4.57
    benzyl alcohol 13.47
    2-ethylhexanol 2.64
    isooctanol 3.51
    dipropyl ether 1.86
    1,2-dichlorobenzene 10.34
    ethyl lactate 8.81
    propylene carbonate 20.97
    n-methylformamide 20.12
    2-pentanol 1.82
    n-pentane 0.02
    1-propoxy-2-propanol 11.02
    1-methoxy-2-propyl acetate 13.32
    2-(2-methoxypropoxy) propanol 14.64
    mesitylene 1.01
    ε-caprolactone 29.91
    p-cymene 1.98
    epichlorohydrin 35.63
    1,1,1-trichloroethane 5.64
    2-aminoethanol 3.22
    morpholine-4-carbaldehyde 44.93
    sulfolane 34.11
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 8.58
    n-hexyl acetate 11.84
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 19.65
    sec-butyl acetate 5.0
    tert-butyl acetate 5.22
    decalin 0.08
    glycerin 5.27
    diglyme 32.49
    acrylic acid 8.13
    isopropyl myristate 4.9
    n-butyric acid 11.14
    acetyl acetate 8.9
    di(2-ethylhexyl) phthalate 8.04
    ethyl propionate 7.47
    nitromethane 29.94
    1,2-diethoxyethane 12.23
    benzonitrile 23.72
    trioctyl phosphate 5.43
    1-bromopropane 3.2
    gamma-valerolactone 64.83
    n-decanol 3.95
    triethyl phosphate 5.35
    4-methyl-2-pentanol 1.24
    propionitrile 12.38
    vinylene carbonate 26.83
    1,1,2-trichlorotrifluoroethane 30.61
    DMS 11.39
    cumene 1.14
    2-octanol 3.53
    2-hexanone 11.74
    octyl acetate 7.19
    limonene 2.08
    1,2-dimethoxyethane 23.98
    ethyl orthosilicate 4.37
    tributyl phosphate 6.2
    diacetone alcohol 11.13
    N,N-dimethylaniline 5.15
    acrylonitrile 22.64
    aniline 8.98
    1,3-propanediol 6.37
    bromobenzene 8.13
    dibromomethane 11.12
    1,1,2,2-tetrachloroethane 27.14
    2-methyl-cyclohexyl acetate 7.66
    tetrabutyl urea 11.21
    diisobutyl methanol 1.5
    2-phenylethanol 12.72
    styrene 2.69
    dioctyl adipate 9.04
    dimethyl sulfate 12.61
    ethyl butyrate 8.31
    methyl lactate 11.03
    butyl lactate 14.02
    diethyl carbonate 6.54
    propanediol butyl ether 13.25
    triethyl orthoformate 6.45
    p-tert-butyltoluene 1.58
    methyl 4-tert-butylbenzoate 14.48
    morpholine 18.0
    tert-butylamine 0.81
    n-dodecanol 2.82
    dimethoxymethane 16.44
    ethylene carbonate 19.25
    cyrene 20.46
    2-ethoxyethyl acetate 21.67
    2-ethylhexyl acetate 5.66
    1,2,4-trichlorobenzene 13.5
    4-methylpyridine 24.05
    dibutyl ether 3.66
    2,6-dimethyl-4-heptanol 1.5
    DEF 22.58
    dimethyl isosorbide 25.7
    tetrachloroethylene 15.49
    eugenol 19.37
    triacetin 15.85
    span 80 12.17
    1,4-butanediol 3.72
    1,1-dichloroethane 7.56
    2-methyl-1-pentanol 3.93
    methyl formate 17.78
    2-methyl-1-butanol 3.19
    n-decane 0.22
    butyronitrile 11.15
    3,7-dimethyl-1-octanol 3.51
    1-chlorooctane 1.9
    1-chlorotetradecane 0.85
    n-nonane 0.14
    undecane 0.17
    tert-butylcyclohexane 0.06
    cyclooctane 0.03
    cyclopentanol 4.73
    tetrahydropyran 8.9
    tert-amyl methyl ether 1.93
    2,5,8-trioxanonane 24.93
    1-hexene 0.21
    2-isopropoxyethanol 8.84
    2,2,2-trifluoroethanol 6.98
    methyl butyrate 12.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction