Isogermafurenolide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    20267-89-4

    Molecular formula
    C15H20O2

    SMILES
    CC1=C2C[C@H]([C@](C[C@@H]2OC1=O)(C)C=C)C(=C)C

    Safety labels

  • Odor profile

    Fragrance
    Sweet 60.85%
    Woody 60.64%
    Spicy 49.91%
    Mint 43.66%
    Citrus 40.94%
    Herbal 40.34%
    Fruity 40.3%
    Tobacco 36.58%
    Green 33.9%
    Fresh 33.63%

     

    Flavor
    Minty 41.88%
    Herbal 36.54%
    Spice 25.71%
    Fresh 24.86%
    Bitter 24.75%
    Woody 24.49%
    Mint 23.71%
    Basil 22.49%
    Spicy 21.28%
    Spearmint 20.33%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    8.31 (weak base)

    Molecular weight
    232.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    361°C

    Flash point

    • 144.61 ˚C est.

  • Synonyms

    • Isogermafurenolide
    • 20267-89-4
    • RefChem:149375
    • (5S,6S,7aS)-6-ethenyl-3,6-dimethyl-5-prop-1-en-2-yl-4,5,7,7a-tetrahydro-1-benzofuran-2-one
    • IEOHWPUTLCTSCQ-RMTCENKZSA-N
    • CHEMBL513373
    • orb1942732
    • SCHEMBL31070253
    • BDBM50594957
    • HY-N12358
    • CS-0898962
    • D85075
    • 20267-89-4

  • Applications

    Isogermafurenolide (CAS 20267-89-4) is typically used as an odorant or fragrance ingredient in perfumery, and is also considered for cosmetic and personal-care scented formulations. It can serve as an organic synthesis intermediate, providing a building block for more complex aroma compounds or specialty lactones used in fragrance blends. In household products, it may be used as a fragrance additive in cleaners and detergents to enhance scent. It may be evaluated for use in coatings, inks, or polymer formulations as a fragrance additive or odor-masking agent. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 396.01
    methanol 490.02
    isopropanol 449.58
    water 0.75
    ethyl acetate 482.66
    n-propanol 419.07
    acetone 437.68
    n-butanol 386.96
    acetonitrile 395.55
    DMF 908.05
    toluene 593.78
    isobutanol 336.6
    1,4-dioxane 1003.85
    methyl acetate 444.92
    THF 1298.13
    2-butanone 521.2
    n-pentanol 200.8
    sec-butanol 387.31
    n-hexane 9.19
    ethylene glycol 60.15
    NMP 555.41
    cyclohexane 34.21
    DMSO 307.18
    n-butyl acetate 305.78
    n-octanol 100.64
    chloroform 1607.91
    n-propyl acetate 241.02
    acetic acid 235.94
    dichloromethane 1207.58
    cyclohexanone 661.31
    propylene glycol 123.97
    isopropyl acetate 342.75
    DMAc 615.07
    2-ethoxyethanol 299.73
    isopentanol 383.75
    n-heptane 7.02
    ethyl formate 264.45
    1,2-dichloroethane 628.97
    n-hexanol 283.49
    2-methoxyethanol 596.77
    isobutyl acetate 176.4
    tetrachloromethane 173.65
    n-pentyl acetate 195.56
    transcutol 1419.14
    n-heptanol 120.24
    ethylbenzene 193.06
    MIBK 304.84
    2-propoxyethanol 508.16
    tert-butanol 470.41
    MTBE 377.51
    2-butoxyethanol 254.73
    propionic acid 223.92
    o-xylene 252.38
    formic acid 118.25
    diethyl ether 351.74
    m-xylene 352.19
    p-xylene 251.13
    chlorobenzene 518.19
    dimethyl carbonate 233.04
    n-octane 3.85
    formamide 251.44
    cyclopentanone 723.27
    2-pentanone 409.97
    anisole 413.91
    cyclopentyl methyl ether 468.16
    gamma-butyrolactone 681.25
    1-methoxy-2-propanol 550.22
    pyridine 862.19
    3-pentanone 295.78
    furfural 614.58
    n-dodecane 4.23
    diethylene glycol 342.06
    diisopropyl ether 118.35
    tert-amyl alcohol 354.82
    acetylacetone 421.68
    n-hexadecane 5.15
    acetophenone 330.31
    methyl propionate 366.68
    isopentyl acetate 301.07
    trichloroethylene 1327.89
    n-nonanol 94.42
    cyclohexanol 353.33
    benzyl alcohol 299.46
    2-ethylhexanol 137.22
    isooctanol 108.25
    dipropyl ether 118.93
    1,2-dichlorobenzene 426.59
    ethyl lactate 129.88
    propylene carbonate 414.31
    n-methylformamide 398.36
    2-pentanol 288.69
    n-pentane 15.66
    1-propoxy-2-propanol 321.78
    1-methoxy-2-propyl acetate 391.51
    2-(2-methoxypropoxy) propanol 278.64
    mesitylene 168.56
    ε-caprolactone 547.74
    p-cymene 94.41
    epichlorohydrin 962.1
    1,1,1-trichloroethane 572.98
    2-aminoethanol 170.28
    morpholine-4-carbaldehyde 777.41
    sulfolane 481.36
    2,2,4-trimethylpentane 14.54
    2-methyltetrahydrofuran 742.03
    n-hexyl acetate 265.87
    isooctane 13.82
    2-(2-butoxyethoxy)ethanol 387.34
    sec-butyl acetate 211.22
    tert-butyl acetate 323.55
    decalin 21.25
    glycerin 170.22
    diglyme 654.36
    acrylic acid 192.45
    isopropyl myristate 99.5
    n-butyric acid 360.21
    acetyl acetate 287.28
    di(2-ethylhexyl) phthalate 122.9
    ethyl propionate 226.6
    nitromethane 450.36
    1,2-diethoxyethane 371.1
    benzonitrile 445.86
    trioctyl phosphate 74.94
    1-bromopropane 346.49
    gamma-valerolactone 822.21
    n-decanol 67.82
    triethyl phosphate 97.25
    4-methyl-2-pentanol 196.56
    propionitrile 370.76
    vinylene carbonate 422.49
    1,1,2-trichlorotrifluoroethane 431.32
    DMS 269.65
    cumene 118.38
    2-octanol 83.23
    2-hexanone 244.3
    octyl acetate 124.16
    limonene 107.15
    1,2-dimethoxyethane 515.39
    ethyl orthosilicate 96.46
    tributyl phosphate 97.16
    diacetone alcohol 337.75
    N,N-dimethylaniline 234.82
    acrylonitrile 451.69
    aniline 547.02
    1,3-propanediol 296.62
    bromobenzene 528.94
    dibromomethane 719.57
    1,1,2,2-tetrachloroethane 960.69
    2-methyl-cyclohexyl acetate 177.77
    tetrabutyl urea 116.78
    diisobutyl methanol 85.24
    2-phenylethanol 339.51
    styrene 237.28
    dioctyl adipate 142.59
    dimethyl sulfate 255.08
    ethyl butyrate 188.96
    methyl lactate 207.29
    butyl lactate 170.71
    diethyl carbonate 140.62
    propanediol butyl ether 252.21
    triethyl orthoformate 141.55
    p-tert-butyltoluene 89.57
    methyl 4-tert-butylbenzoate 230.51
    morpholine 1090.92
    tert-butylamine 275.6
    n-dodecanol 49.53
    dimethoxymethane 622.33
    ethylene carbonate 357.59
    cyrene 254.88
    2-ethoxyethyl acetate 311.86
    2-ethylhexyl acetate 231.42
    1,2,4-trichlorobenzene 473.51
    4-methylpyridine 942.3
    dibutyl ether 109.79
    2,6-dimethyl-4-heptanol 85.24
    DEF 420.56
    dimethyl isosorbide 455.94
    tetrachloroethylene 558.49
    eugenol 246.26
    triacetin 245.49
    span 80 213.05
    1,4-butanediol 100.62
    1,1-dichloroethane 698.07
    2-methyl-1-pentanol 222.73
    methyl formate 293.15
    2-methyl-1-butanol 336.24
    n-decane 7.37
    butyronitrile 407.04
    3,7-dimethyl-1-octanol 131.71
    1-chlorooctane 55.98
    1-chlorotetradecane 20.95
    n-nonane 5.86
    undecane 5.44
    tert-butylcyclohexane 19.07
    cyclooctane 10.71
    cyclopentanol 342.43
    tetrahydropyran 835.57
    tert-amyl methyl ether 247.78
    2,5,8-trioxanonane 420.78
    1-hexene 65.82
    2-isopropoxyethanol 233.97
    2,2,2-trifluoroethanol 119.49
    methyl butyrate 271.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction