Isodecyl Salicylate

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  • Identifiers

    CAS number
    85252-25-1

    Molecular formula
    C17H26O3

    SMILES
    CC(C)CCCCCCCOC(=O)C1=CC=CC=C1O

    Safety labels

  • Odor profile

    Fragrance
    Floral 79.49%
    Sweet 64.73%
    Balsamic 63.07%
    Fresh 45.16%
    Rose 40.26%
    Herbal 39.73%
    Lily 34.48%
    Waxy 30.35%
    Spicy 29.9%
    Fruity 29.6%

     

    Flavor
    Herbal 50.61%
    Woody 43.29%
    Warm 28.95%
    Oily 28.43%
    Mild 28.09%
    Balsam 26.52%
    Spicy 25.19%
    Spice 23.82%
    Floral 22.81%
    Bland 22.78%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.6

    pKa est.
    8.08 (weak base)

    Molecular weight
    278.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    347°C

    Flash point

    • 161.46 ˚C est.

  • Synonyms

    • Isodecyl salicylate
    • 85252-25-1
    • EINECS 286-542-0
    • Keratoplast
    • S7097PFP4C
    • Benzoic acid, 2-hydroxy-, isodecyl ester
    • EDESAL
    • DERMOL IDSA
    • RefChem:791848
    • DTXSID90234458
    • ISODECYL SALICYLATE [INCI]
    • 286-542-0
    • 82708-24-5
    • 8-methylnonyl 2-hydroxybenzoate
    • UNII-S7097PFP4C
    • isodecylsalicylate
    • 8-Methylnonyl salicylate
    • SCHEMBL597679
    • SCHEMBL30420892
    • PJTNSWOJMXNNFG-UHFFFAOYSA-N
    • DTXSID001010022
    • NS00022839
    • Q27288750
    • 1027820-56-9
    • 85252-25-1

  • Applications

    Isodecyl Salicylate (CAS 85252-25-1) is commonly used in cosmetics and personal care as a skin-conditioning emollient that provides slip and a smooth feel in lotions, creams, and makeup. It also functions as a solvent and carrier for fragrance oils and cosmetic actives, aiding dissolution and delivery of ingredients in formulations. In the perfumery and fragrance sector, it serves as a processing solvent and carrier for aroma materials. In polymers and coatings, it can act as a plasticizer or processing aid to improve flexibility and workability of resin systems and coatings. In adhesives and inks, it may be employed as a processing additive to adjust viscosity and facilitate spreading. Subject to local regulations and formulation limits, Isodecyl Salicylate is chosen where a non-polar, lipophilic ester is desired.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7987.94
    methanol 5588.92
    isopropanol 6177.59
    water 0.05
    ethyl acetate 4902.72
    n-propanol 6638.4
    acetone 10041.43
    n-butanol 4648.55
    acetonitrile 3546.39
    DMF 6027.61
    toluene 1072.66
    isobutanol 3995.65
    1,4-dioxane 3745.26
    methyl acetate 3297.59
    THF 8347.09
    2-butanone 6346.18
    n-pentanol 2014.19
    sec-butanol 4113.11
    n-hexane 91.87
    ethylene glycol 188.44
    NMP 3162.94
    cyclohexane 256.64
    DMSO 6878.03
    n-butyl acetate 1812.94
    n-octanol 332.05
    chloroform 4382.31
    n-propyl acetate 1990.22
    acetic acid 1704.04
    dichloromethane 4949.71
    cyclohexanone 5678.85
    propylene glycol 768.46
    isopropyl acetate 2311.42
    DMAc 3110.67
    2-ethoxyethanol 2074.73
    isopentanol 2783.17
    n-heptane 28.34
    ethyl formate 1688.41
    1,2-dichloroethane 5253.06
    n-hexanol 1302.78
    2-methoxyethanol 4713.19
    isobutyl acetate 1005.12
    tetrachloromethane 417.05
    n-pentyl acetate 878.92
    transcutol 4449.93
    n-heptanol 407.47
    ethylbenzene 363.86
    MIBK 1870.19
    2-propoxyethanol 2230.93
    tert-butanol 4378.85
    MTBE 3938.13
    2-butoxyethanol 944.8
    propionic acid 1785.06
    o-xylene 463.81
    formic acid 260.11
    diethyl ether 4388.26
    m-xylene 549.67
    p-xylene 471.56
    chlorobenzene 1494.36
    dimethyl carbonate 649.5
    n-octane 15.64
    formamide 833.35
    cyclopentanone 5977.07
    2-pentanone 5102.76
    anisole 938.27
    cyclopentyl methyl ether 2996.07
    gamma-butyrolactone 4676.71
    1-methoxy-2-propanol 3500.73
    pyridine 3501.32
    3-pentanone 2444.92
    furfural 2210.29
    n-dodecane 14.2
    diethylene glycol 908.17
    diisopropyl ether 712.86
    tert-amyl alcohol 2907.24
    acetylacetone 3114.43
    n-hexadecane 17.86
    acetophenone 821.06
    methyl propionate 3066.3
    isopentyl acetate 1501.9
    trichloroethylene 6402.51
    n-nonanol 290.29
    cyclohexanol 2783.49
    benzyl alcohol 782.63
    2-ethylhexanol 539.81
    isooctanol 353.57
    dipropyl ether 773.25
    1,2-dichlorobenzene 1002.45
    ethyl lactate 521.06
    propylene carbonate 1874.93
    n-methylformamide 2943.64
    2-pentanol 2553.15
    n-pentane 99.34
    1-propoxy-2-propanol 1437.32
    1-methoxy-2-propyl acetate 1425.0
    2-(2-methoxypropoxy) propanol 626.62
    mesitylene 294.6
    ε-caprolactone 3303.22
    p-cymene 163.76
    epichlorohydrin 6742.35
    1,1,1-trichloroethane 3339.01
    2-aminoethanol 1163.97
    morpholine-4-carbaldehyde 2396.87
    sulfolane 4557.14
    2,2,4-trimethylpentane 62.88
    2-methyltetrahydrofuran 6330.31
    n-hexyl acetate 1020.96
    isooctane 51.98
    2-(2-butoxyethoxy)ethanol 1118.42
    sec-butyl acetate 1199.98
    tert-butyl acetate 2008.58
    decalin 79.71
    glycerin 540.03
    diglyme 2222.96
    acrylic acid 893.85
    isopropyl myristate 296.76
    n-butyric acid 3503.05
    acetyl acetate 1296.6
    di(2-ethylhexyl) phthalate 237.32
    ethyl propionate 1449.1
    nitromethane 4003.63
    1,2-diethoxyethane 1689.22
    benzonitrile 1106.36
    trioctyl phosphate 181.16
    1-bromopropane 3149.91
    gamma-valerolactone 5740.11
    n-decanol 198.22
    triethyl phosphate 275.72
    4-methyl-2-pentanol 819.27
    propionitrile 2883.34
    vinylene carbonate 1335.46
    1,1,2-trichlorotrifluoroethane 2197.51
    DMS 725.12
    cumene 203.41
    2-octanol 279.65
    2-hexanone 2190.53
    octyl acetate 380.92
    limonene 317.8
    1,2-dimethoxyethane 3099.86
    ethyl orthosilicate 264.14
    tributyl phosphate 250.44
    diacetone alcohol 1964.64
    N,N-dimethylaniline 439.23
    acrylonitrile 2492.09
    aniline 1522.84
    1,3-propanediol 2119.1
    bromobenzene 1466.51
    dibromomethane 3304.76
    1,1,2,2-tetrachloroethane 5292.77
    2-methyl-cyclohexyl acetate 575.25
    tetrabutyl urea 316.9
    diisobutyl methanol 264.85
    2-phenylethanol 666.56
    styrene 556.76
    dioctyl adipate 417.3
    dimethyl sulfate 944.64
    ethyl butyrate 941.65
    methyl lactate 818.96
    butyl lactate 623.92
    diethyl carbonate 491.12
    propanediol butyl ether 792.0
    triethyl orthoformate 497.33
    p-tert-butyltoluene 161.33
    methyl 4-tert-butylbenzoate 568.01
    morpholine 6958.81
    tert-butylamine 2159.57
    n-dodecanol 140.12
    dimethoxymethane 3422.51
    ethylene carbonate 1306.14
    cyrene 557.33
    2-ethoxyethyl acetate 1172.79
    2-ethylhexyl acetate 980.23
    1,2,4-trichlorobenzene 1190.74
    4-methylpyridine 3488.11
    dibutyl ether 595.58
    2,6-dimethyl-4-heptanol 264.85
    DEF 3475.74
    dimethyl isosorbide 1026.5
    tetrachloroethylene 2453.82
    eugenol 531.59
    triacetin 699.8
    span 80 540.32
    1,4-butanediol 544.81
    1,1-dichloroethane 5474.91
    2-methyl-1-pentanol 1382.41
    methyl formate 1407.55
    2-methyl-1-butanol 2833.43
    n-decane 26.44
    butyronitrile 3254.47
    3,7-dimethyl-1-octanol 404.67
    1-chlorooctane 239.33
    1-chlorotetradecane 71.62
    n-nonane 24.02
    undecane 18.7
    tert-butylcyclohexane 68.25
    cyclooctane 44.68
    cyclopentanol 3123.88
    tetrahydropyran 7111.05
    tert-amyl methyl ether 1884.46
    2,5,8-trioxanonane 1142.55
    1-hexene 756.52
    2-isopropoxyethanol 1303.61
    2,2,2-trifluoroethanol 373.29
    methyl butyrate 2214.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction