Isocetyl Palmitate

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  • Identifiers

    CAS number
    127770-27-8

    Molecular formula
    C32H64O2

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C

    Safety labels

  • Odor profile

    Fragrance
    Waxy 77.47%
    Fatty 61.31%
    Oily 50.97%
    Odorless 33.34%
    Creamy 22.09%
    Sweet 21.75%
    Balsamic 18.45%
    Clean 17.7%
    Dairy 17.12%
    Milky 16.82%

     

    Flavor
    Waxy 55.74%
    Mild 40.89%
    Fatty 38.93%
    Oily 36.76%
    Bland 34.56%
    Faint 30.62%
    Fat 28.53%
    Alkane 28.13%
    Slightly waxy 25.28%
    Soapy 23.78%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    14.9

    pKa est.
    8.88 (weak base)

    Molecular weight
    480.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    513°C

    Flash point

    • 228.99 ˚C est.

  • Synonyms

    • Isocetyl palmitate
    • Hexadecanoic acid, isohexadecyl ester
    • UNII-355356620Z
    • TEGOSOFT HP
    • DERMOL ICP
    • ISOHEXADECYL PALMITATE
    • AEC ISOCETYL PALMITATE
    • 355356620Z
    • DTXSID2074584
    • PALMITIC ACID, ISOCETYL ESTER
    • HEXADECANOIC ACID, ISOCETYL ESTER
    • RefChem:149151
    • DTXCID9033894
    • ISOCETYL PALMITATE [INCI]
    • 127770-27-8
    • 14-METHYLPENTADECYL HEXADECANOATE
    • SCHEMBL5873231
    • OUZOBPPZPCBJAR-UHFFFAOYSA-N
    • Q27256425
    • 127770-27-8

  • Applications

    Isocetyl Palmitate (CAS 127770-27-8) is a fatty ester commonly used as an emollient and carrier in cosmetics and personal care; typical applications include as an emollient in moisturizers and facial oils, serving as a fragrance carrier or base for perfumery formulations, acting as a lubricating processing aid in coatings and inks, functioning as a softening/lubricating additive in polymers/plastics to aid processing and surface feel, and potentially used as a base component or excipient in topical pharmaceutical formulations depending on local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.48
    methanol 7.32
    isopropanol 7.67
    water 0.05
    ethyl acetate 142.28
    n-propanol 12.35
    acetone 61.15
    n-butanol 17.09
    acetonitrile 19.41
    DMF 86.45
    toluene 62.96
    isobutanol 15.61
    1,4-dioxane 126.21
    methyl acetate 74.13
    THF 351.94
    2-butanone 105.96
    n-pentanol 18.04
    sec-butanol 19.61
    n-hexane 18.73
    ethylene glycol 0.82
    NMP 478.01
    cyclohexane 106.04
    DMSO 108.66
    n-butyl acetate 183.44
    n-octanol 47.87
    chloroform 535.38
    n-propyl acetate 180.53
    acetic acid 32.24
    dichloromethane 543.31
    cyclohexanone 467.33
    propylene glycol 2.74
    isopropyl acetate 164.72
    DMAc 280.17
    2-ethoxyethanol 43.57
    isopentanol 29.26
    n-heptane 24.69
    ethyl formate 50.5
    1,2-dichloroethane 298.42
    n-hexanol 19.55
    2-methoxyethanol 34.41
    isobutyl acetate 137.94
    tetrachloromethane 146.44
    n-pentyl acetate 381.39
    transcutol 412.12
    n-heptanol 37.98
    ethylbenzene 57.46
    MIBK 144.66
    2-propoxyethanol 53.03
    tert-butanol 23.42
    MTBE 88.3
    2-butoxyethanol 102.77
    propionic acid 35.38
    o-xylene 72.68
    formic acid 6.21
    diethyl ether 59.01
    m-xylene 55.96
    p-xylene 90.1
    chlorobenzene 145.74
    dimethyl carbonate 39.15
    n-octane 14.39
    formamide 13.25
    cyclopentanone 417.53
    2-pentanone 122.1
    anisole 114.19
    cyclopentyl methyl ether 246.84
    gamma-butyrolactone 373.24
    1-methoxy-2-propanol 46.86
    pyridine 159.12
    3-pentanone 128.81
    furfural 251.12
    n-dodecane 6.95
    diethylene glycol 16.16
    diisopropyl ether 51.92
    tert-amyl alcohol 47.19
    acetylacetone 210.63
    n-hexadecane 8.84
    acetophenone 179.55
    methyl propionate 98.47
    isopentyl acetate 216.12
    trichloroethylene 588.32
    n-nonanol 53.95
    cyclohexanol 76.37
    benzyl alcohol 45.68
    2-ethylhexanol 41.74
    isooctanol 51.13
    dipropyl ether 126.74
    1,2-dichlorobenzene 228.26
    ethyl lactate 59.38
    propylene carbonate 261.58
    n-methylformamide 28.25
    2-pentanol 20.03
    n-pentane 10.21
    1-propoxy-2-propanol 81.35
    1-methoxy-2-propyl acetate 199.18
    2-(2-methoxypropoxy) propanol 129.93
    mesitylene 53.9
    ε-caprolactone 444.68
    p-cymene 63.73
    epichlorohydrin 384.27
    1,1,1-trichloroethane 444.97
    2-aminoethanol 3.73
    morpholine-4-carbaldehyde 238.38
    sulfolane 712.82
    2,2,4-trimethylpentane 19.89
    2-methyltetrahydrofuran 310.77
    n-hexyl acetate 313.45
    isooctane 9.52
    2-(2-butoxyethoxy)ethanol 146.98
    sec-butyl acetate 176.48
    tert-butyl acetate 273.06
    decalin 41.36
    glycerin 6.42
    diglyme 438.83
    acrylic acid 25.03
    isopropyl myristate 101.61
    n-butyric acid 98.42
    acetyl acetate 124.31
    di(2-ethylhexyl) phthalate 74.56
    ethyl propionate 177.97
    nitromethane 97.71
    1,2-diethoxyethane 230.55
    benzonitrile 76.09
    trioctyl phosphate 53.51
    1-bromopropane 159.24
    gamma-valerolactone 525.97
    n-decanol 31.61
    triethyl phosphate 151.16
    4-methyl-2-pentanol 23.43
    propionitrile 28.58
    vinylene carbonate 179.48
    1,1,2-trichlorotrifluoroethane 237.22
    DMS 136.85
    cumene 48.57
    2-octanol 46.49
    2-hexanone 148.8
    octyl acetate 113.59
    limonene 119.73
    1,2-dimethoxyethane 174.63
    ethyl orthosilicate 152.4
    tributyl phosphate 81.36
    diacetone alcohol 163.97
    N,N-dimethylaniline 94.53
    acrylonitrile 28.75
    aniline 50.14
    1,3-propanediol 9.55
    bromobenzene 204.61
    dibromomethane 316.68
    1,1,2,2-tetrachloroethane 587.53
    2-methyl-cyclohexyl acetate 233.97
    tetrabutyl urea 128.7
    diisobutyl methanol 45.44
    2-phenylethanol 46.57
    styrene 63.83
    dioctyl adipate 181.61
    dimethyl sulfate 121.55
    ethyl butyrate 244.06
    methyl lactate 38.18
    butyl lactate 178.33
    diethyl carbonate 132.23
    propanediol butyl ether 73.17
    triethyl orthoformate 224.98
    p-tert-butyltoluene 58.48
    methyl 4-tert-butylbenzoate 267.02
    morpholine 147.26
    tert-butylamine 20.7
    n-dodecanol 21.32
    dimethoxymethane 67.93
    ethylene carbonate 166.71
    cyrene 145.24
    2-ethoxyethyl acetate 336.55
    2-ethylhexyl acetate 208.74
    1,2,4-trichlorobenzene 288.08
    4-methylpyridine 165.16
    dibutyl ether 179.5
    2,6-dimethyl-4-heptanol 45.44
    DEF 188.81
    dimethyl isosorbide 381.88
    tetrachloroethylene 350.33
    eugenol 155.16
    triacetin 355.27
    span 80 130.93
    1,4-butanediol 5.26
    1,1-dichloroethane 229.3
    2-methyl-1-pentanol 32.96
    methyl formate 25.41
    2-methyl-1-butanol 29.05
    n-decane 18.8
    butyronitrile 38.11
    3,7-dimethyl-1-octanol 62.31
    1-chlorooctane 88.77
    1-chlorotetradecane 24.66
    n-nonane 18.33
    undecane 10.42
    tert-butylcyclohexane 27.83
    cyclooctane 32.12
    cyclopentanol 63.6
    tetrahydropyran 225.72
    tert-amyl methyl ether 119.12
    2,5,8-trioxanonane 220.83
    1-hexene 36.73
    2-isopropoxyethanol 49.07
    2,2,2-trifluoroethanol 26.27
    methyl butyrate 239.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction