Iodine

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  • Identifiers

    CAS number
    7553-56-2

    Molecular formula
    I2

    SMILES
    II

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Fishy 57.46%
    Odorless 51.66%
    Cheesy 42.69%
    Ripe 39.08%
    Alcoholic 25.09%
    Fermented 24.72%
    Oily 24.39%
    Sulfurous 19.86%
    Pungent 19.84%
    Meaty 19.65%

     

    Flavor
    Fishy 32.79%
    Egg 30.92%
    Odorless 27.37%
    Ammoniacal 26.04%
    Rotten 25.15%
    Sulfur 23.86%
    Garlic 22.97%
    Decomposing cabbage 22.53%
    Bitter 20.87%
    Formyl 19.9%

     

    Odor impact est.
    High

    Odor threshold

    • Odor low= 9.00 mg/cu m; Odor high= 9.00 mg/cu m; Irritating Concn= 2.0 mg/cu m

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    -115.8 (strong acid)

    Molecular weight
    253.8089 g/mol

    Melting point expt.

    • 236 °F (NIOSH, 2024)
    • 113.7 °C
    • 113.6 °C
    • 114 °C
    • 236 °F

    Boiling point

    • 365 °F at 760 mmHg (NIOSH, 2024)
    • 184.4 °C
    • 184 °C
    • 365 °F

    Flash point

    • 298.75 ˚C est.

    Solubility expt.

    • 0.01 % (NIOSH, 2024)
    • For more Solubility (Complete) data for IODINE, ELEMENTAL (9 total), please visit the HSDB record page.
    • Dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide to form purple solns.
    • 2.719 g in cyclohexane; 23 g/100 cc in methanol at 25 °C; 20.5 g/100 cc in alcohol at 15 °C; 20.6 g/100 cc in ether at 17 °C
    • 197 g/kg in carbon disulfide at 25 °C; 19.2 g/kg in carbon tetrachloride at 25 °C; 337.3 g/kg in ether at 25 °C; 164.0 g/kg in benzene at 25 °C; 27.1 g/kg in ethanol at 25 °C; 49.7 g/kg in chloroform at 25 °C; 49.7 g/kg in chloroform at 25 °C; 13.2 g/kg in n-hexane at 25 °C; 97 g/kg in butan-2-ol at 25 °C; 157 g/kg in ethyl acetate at 25 °C; 182.5 g/kg in toluene at 25 °C
    • 14.6 g/100 g in bromoethane at 25 °C; 1.73 g/100 g in n-heptane at 25 °C; 9.7 g/100 g in glycerol at 25 °C; 33.7 g/100 g in diethyl ether at 25 °C; 19.7 g/100 g in carbon disulfide at 25 °C
    • For more Solubility (Complete) data for IODINE, ELEMENTAL (8 total), please visit the HSDB record page.
    • 0.33 mg/mL at 25 °C
    • Solubility in water, g/100ml at 20 °C: 0.03
    • 0.01%

  • Synonyms

    • iodine
    • 7553-56-2
    • I
    • Molecular iodine
    • Diiodine
    • Iodine crystals
    • Iodine sublimed
    • Tincture iodine
    • Vistarin
    • Eranol
    • Iodio
    • Iode
    • Iosan superdip
    • Jood
    • Iodine-127
    • Iodine colloidal
    • Actomar
    • Iodine tincture
    • Iodine Tincture USP
    • iodium
    • Jodosan
    • Tegodyne
    • Iodum
    • Caswell No. 501
    • Iodine strong
    • 12190-71-5
    • Iodine (resublimed)
    • Iodine ((127)I2)
    • HSDB 34
    • CCRIS 9223
    • Jod [German, Polish]
    • I2
    • Iodine mild
    • EINECS 231-442-4
    • MFCD00011355
    • NSC 42355
    • NSC-42355
    • DTXSID7034672
    • Jod
    • UNII-9679TC07X4
    • CHEBI:17606
    • Iodine [USP:JAN]
    • Iodine I-131
    • 9679TC07X4
    • DTXCID5014672
    • EC 231-442-4
    • iodine (ii)
    • Iodine, crystalline
    • NSC42355
    • Iodine (USP:JAN)
    • IODINE [II]
    • IODINE (MART.)
    • IODINE [MART.]
    • Iodio [Italian]
    • Jod (GERMAN, POLISH)
    • IODINE (EP IMPURITY)
    • IODINE [EP IMPURITY]
    • Jood [Dutch]
    • IODINE (EP MONOGRAPH)
    • IODINE [EP MONOGRAPH]
    • IODE [French]
    • IODINE (USP MONOGRAPH)
    • Iodine [JAN]
    • IODINE [USP MONOGRAPH]
    • diiodane
    • Iodine 127
    • EPA Pesticide Chemical Code 046905
    • exceed
    • Bovadine
    • Ecodyne
    • Halfdyne
    • Megadyne
    • Monodyne
    • Optidyne
    • Pentadyne
    • Predyne
    • Prodyne
    • Proteat
    • Teradyne
    • Ascend
    • iodine-iodide
    • iodonium iodide
    • Cadex
    • DermaFive
    • Diatomic iodine
    • QuarterMatePlus
    • Sweat
    • UdderDyne
    • AlphaPro
    • BoviSoft
    • Teatguard Plus
    • AI3-08544
    • Della Barrier
    • Gil Barricade
    • Bio Iodine
    • Gil Surpass
    • Winter Dine
    • BoviSoft Barrier
    • Bovi-Kote
    • Bovi-Sure
    • Iodine,
    • Controlled Iodine
    • Eco-Gard
    • Eco-Plus
    • Eco-Star
    • Iodoshield Active
    • Nue Plus
    • Reef Dip
    • Titratable Iodine
    • Udderdine APEX
    • West Dip
    • Defend II
    • Della One Plus
    • I-deal
    • IO Shield
    • IO-Shield
    • IODip
    • Iokote II
    • Barrier Teat Dip
    • Gil Econo Dip
    • Gil Ultra Dip
    • Iodine, elemental
    • Metz Sani-Shield
    • Confidence .5
    • Gil Teat Dip
    • Gil Tri-Stat
    • Io-Link
    • Proteat-2

  • Applications

    Iodine (CAS 7553-56-2) is used as a halogenation reagent in organic synthesis and as a key source of iodine for iodination reactions in pharmaceutical and specialty chemical production; it also appears in iodine-based sanitizers (iodophors) for disinfection in healthcare, dairy, and other cleaning contexts; in food processing it is added as iodized salt and other iodine-containing additives to address dietary iodine; in animal nutrition it serves as a trace-element supplement in feed formulations; and in industrial and analytical settings it is used as a reagent or intermediate for iodine-containing compounds and for quality-control tests.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 354.62
    methanol 285.14
    isopropanol 304.7
    water 1.22
    ethyl acetate 701.75
    n-propanol 329.76
    acetone 937.55
    n-butanol 369.12
    acetonitrile 494.39
    DMF 1106.73
    toluene 709.18
    isobutanol 279.29
    1,4-dioxane 1330.05
    methyl acetate 599.6
    THF 1821.84
    2-butanone 757.8
    n-pentanol 291.38
    sec-butanol 310.28
    n-hexane 264.49
    ethylene glycol 98.22
    NMP 1552.69
    cyclohexane 520.02
    DMSO 1101.57
    n-butyl acetate 715.22
    n-octanol 376.71
    chloroform 1831.49
    n-propyl acetate 508.68
    acetic acid 536.18
    dichloromethane 1461.03
    cyclohexanone 1439.58
    propylene glycol 130.55
    isopropyl acetate 507.7
    DMAc 836.37
    2-ethoxyethanol 387.83
    isopentanol 329.8
    n-heptane 317.22
    ethyl formate 415.84
    1,2-dichloroethane 993.26
    n-hexanol 457.17
    2-methoxyethanol 587.12
    isobutyl acetate 364.39
    tetrachloromethane 547.18
    n-pentyl acetate 584.05
    transcutol 1520.73
    n-heptanol 331.77
    ethylbenzene 385.1
    MIBK 527.37
    2-propoxyethanol 636.49
    tert-butanol 425.5
    MTBE 540.83
    2-butoxyethanol 485.7
    propionic acid 376.56
    o-xylene 469.49
    formic acid 106.03
    diethyl ether 700.76
    m-xylene 492.91
    p-xylene 481.82
    chlorobenzene 873.8
    dimethyl carbonate 344.68
    n-octane 154.33
    formamide 179.91
    cyclopentanone 1699.54
    2-pentanone 773.49
    anisole 668.67
    cyclopentyl methyl ether 1041.31
    gamma-butyrolactone 1496.6
    1-methoxy-2-propanol 538.59
    pyridine 1225.32
    3-pentanone 657.8
    furfural 1354.54
    n-dodecane 110.06
    diethylene glycol 415.17
    diisopropyl ether 344.12
    tert-amyl alcohol 386.83
    acetylacetone 957.64
    n-hexadecane 124.35
    acetophenone 645.04
    methyl propionate 552.43
    isopentyl acetate 589.01
    trichloroethylene 1824.57
    n-nonanol 331.05
    cyclohexanol 546.31
    benzyl alcohol 402.58
    2-ethylhexanol 388.77
    isooctanol 279.45
    dipropyl ether 658.13
    1,2-dichlorobenzene 828.33
    ethyl lactate 241.3
    propylene carbonate 882.29
    n-methylformamide 384.83
    2-pentanol 332.06
    n-pentane 243.87
    1-propoxy-2-propanol 595.3
    1-methoxy-2-propyl acetate 645.65
    2-(2-methoxypropoxy) propanol 504.97
    mesitylene 384.17
    ε-caprolactone 1096.63
    p-cymene 324.51
    epichlorohydrin 1310.91
    1,1,1-trichloroethane 1181.13
    2-aminoethanol 169.82
    morpholine-4-carbaldehyde 1264.18
    sulfolane 1754.31
    2,2,4-trimethylpentane 129.23
    2-methyltetrahydrofuran 1367.32
    n-hexyl acetate 704.91
    isooctane 120.58
    2-(2-butoxyethoxy)ethanol 666.58
    sec-butyl acetate 377.04
    tert-butyl acetate 626.72
    decalin 227.65
    glycerin 196.77
    diglyme 1203.73
    acrylic acid 382.39
    isopropyl myristate 348.9
    n-butyric acid 549.05
    acetyl acetate 595.72
    di(2-ethylhexyl) phthalate 296.56
    ethyl propionate 461.79
    nitromethane 813.68
    1,2-diethoxyethane 815.9
    benzonitrile 668.33
    trioctyl phosphate 231.17
    1-bromopropane 732.89
    gamma-valerolactone 1503.64
    n-decanol 260.07
    triethyl phosphate 303.87
    4-methyl-2-pentanol 232.36
    propionitrile 440.21
    vinylene carbonate 790.59
    1,1,2-trichlorotrifluoroethane 879.33
    DMS 584.47
    cumene 271.68
    2-octanol 284.49
    2-hexanone 552.97
    octyl acetate 415.74
    limonene 498.83
    1,2-dimethoxyethane 851.99
    ethyl orthosilicate 310.14
    tributyl phosphate 274.38
    diacetone alcohol 586.74
    N,N-dimethylaniline 506.73
    acrylonitrile 530.31
    aniline 567.4
    1,3-propanediol 269.5
    bromobenzene 1011.91
    dibromomethane 1215.44
    1,1,2,2-tetrachloroethane 1423.3
    2-methyl-cyclohexyl acetate 455.51
    tetrabutyl urea 404.63
    diisobutyl methanol 303.05
    2-phenylethanol 476.52
    styrene 512.88
    dioctyl adipate 445.29
    dimethyl sulfate 559.45
    ethyl butyrate 558.09
    methyl lactate 291.33
    butyl lactate 377.76
    diethyl carbonate 384.76
    propanediol butyl ether 436.76
    triethyl orthoformate 424.77
    p-tert-butyltoluene 332.31
    methyl 4-tert-butylbenzoate 600.39
    morpholine 1198.87
    tert-butylamine 336.47
    n-dodecanol 222.09
    dimethoxymethane 741.43
    ethylene carbonate 618.84
    cyrene 542.31
    2-ethoxyethyl acetate 705.14
    2-ethylhexyl acetate 549.8
    1,2,4-trichlorobenzene 939.57
    4-methylpyridine 1146.37
    dibutyl ether 581.28
    2,6-dimethyl-4-heptanol 303.05
    DEF 796.87
    dimethyl isosorbide 964.9
    tetrachloroethylene 1055.62
    eugenol 546.66
    triacetin 656.53
    span 80 577.23
    1,4-butanediol 140.11
    1,1-dichloroethane 989.46
    2-methyl-1-pentanol 283.4
    methyl formate 362.14
    2-methyl-1-butanol 306.62
    n-decane 169.92
    butyronitrile 494.11
    3,7-dimethyl-1-octanol 337.27
    1-chlorooctane 409.23
    1-chlorotetradecane 198.47
    n-nonane 183.83
    undecane 131.03
    tert-butylcyclohexane 193.33
    cyclooctane 250.85
    cyclopentanol 627.39
    tetrahydropyran 1314.07
    tert-amyl methyl ether 486.41
    2,5,8-trioxanonane 894.31
    1-hexene 457.68
    2-isopropoxyethanol 324.66
    2,2,2-trifluoroethanol 219.93
    methyl butyrate 583.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction