Intricatin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    124166-25-2

    Molecular formula
    C18H16O5

    SMILES
    COC1=CC=C(C=C1)/C=C/2\COC3=C(C2=O)C=CC(=C3O)OC

    Safety labels

  • Odor profile

    Fragrance
    Sweet 71.4%
    Spicy 61.14%
    Vanilla 58.87%
    Floral 47.27%
    Phenolic 45.67%
    Powdery 41.37%
    Balsamic 40.47%
    Creamy 33.48%
    Clove 32.31%
    Aromatic 31.73%

     

    Flavor
    Bitter 85.6%
    Parsley 20.18%
    Lovage 19.92%
    Ethyl benzoate 18.5%
    Cedarleaf 18.47%
    Aniseed 18.42%
    Eugenol 18.37%
    Ripe apricot 18.27%
    Sweet-like 18.13%
    Red fruit 18.07%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.9

    pKa est.
    8.09 (weak base)

    Molecular weight
    312.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    575°C

    Flash point

    • 200.94 ˚C est.

  • Synonyms

    • Intricatin
    • 124166-25-2
    • 7,4'-Dimethoxy-8-hydroxyhomoisoflavone
    • 7,4'-dimethoxy-8-hydroxy-homoisoflavone
    • (3E)-8-hydroxy-7-methoxy-3-[(4-methoxyphenyl)methylidene]chromen-4-one
    • 4H-1-Benzopyran-4-one, 2,3-dihydro-8-hydroxy-7-methoxy-3-((4-methoxyphenyl)methylene)-, (E)-
    • (3E)-8-hydroxy-7-methoxy-3-((4-methoxyphenyl)methylidene)chromen-4-one
    • RefChem:148452
    • CHEMBL265869
    • 124166-25-2

  • Applications

    Intricatin (CAS 124166-25-2) is an industrial chemical commonly evaluated for use as an intermediate in organic synthesis and as a solvent or processing aid. In coatings and inks, it may function as a processing aid or diluent; in polymers, it can serve as a plasticizer or stabilizer; in perfumery and cosmetics, it may act as an odorant or fixative component; in household cleaning formulations, it may serve as a solvent or formulation aid; and in general industrial manufacturing, it is considered a versatile processing chemical, with use governed by formulation requirements and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.07
    methanol 2.2
    isopropanol 3.74
    water 0.0
    ethyl acetate 24.67
    n-propanol 4.03
    acetone 23.39
    n-butanol 3.9
    acetonitrile 16.08
    DMF 26.14
    toluene 8.25
    isobutanol 2.99
    1,4-dioxane 42.26
    methyl acetate 22.37
    THF 119.25
    2-butanone 22.53
    n-pentanol 4.18
    sec-butanol 4.09
    n-hexane 0.26
    ethylene glycol 2.8
    NMP 16.79
    cyclohexane 0.75
    DMSO 64.7
    n-butyl acetate 8.13
    n-octanol 3.07
    chloroform 32.15
    n-propyl acetate 12.06
    acetic acid 19.94
    dichloromethane 44.34
    cyclohexanone 24.47
    propylene glycol 2.6
    isopropyl acetate 15.28
    DMAc 48.75
    2-ethoxyethanol 23.45
    isopentanol 4.42
    n-heptane 0.78
    ethyl formate 8.92
    1,2-dichloroethane 29.96
    n-hexanol 3.7
    2-methoxyethanol 27.85
    isobutyl acetate 7.65
    tetrachloromethane 2.6
    n-pentyl acetate 8.48
    transcutol 68.5
    n-heptanol 3.53
    ethylbenzene 4.21
    MIBK 11.12
    2-propoxyethanol 20.15
    tert-butanol 9.16
    MTBE 9.59
    2-butoxyethanol 12.55
    propionic acid 9.03
    o-xylene 5.68
    formic acid 7.11
    diethyl ether 12.4
    m-xylene 4.63
    p-xylene 5.38
    chlorobenzene 9.05
    dimethyl carbonate 20.07
    n-octane 0.45
    formamide 19.17
    cyclopentanone 38.62
    2-pentanone 16.29
    anisole 14.47
    cyclopentyl methyl ether 19.4
    gamma-butyrolactone 47.46
    1-methoxy-2-propanol 21.09
    pyridine 32.47
    3-pentanone 16.97
    furfural 37.04
    n-dodecane 0.48
    diethylene glycol 20.68
    diisopropyl ether 4.08
    tert-amyl alcohol 6.49
    acetylacetone 36.1
    n-hexadecane 0.58
    acetophenone 16.36
    methyl propionate 20.87
    isopentyl acetate 9.66
    trichloroethylene 60.55
    n-nonanol 4.01
    cyclohexanol 6.25
    benzyl alcohol 10.24
    2-ethylhexanol 3.88
    isooctanol 3.71
    dipropyl ether 10.09
    1,2-dichlorobenzene 10.5
    ethyl lactate 7.9
    propylene carbonate 14.92
    n-methylformamide 11.23
    2-pentanol 3.7
    n-pentane 0.24
    1-propoxy-2-propanol 14.11
    1-methoxy-2-propyl acetate 20.94
    2-(2-methoxypropoxy) propanol 21.43
    mesitylene 3.07
    ε-caprolactone 18.74
    p-cymene 4.15
    epichlorohydrin 78.3
    1,1,1-trichloroethane 17.02
    2-aminoethanol 3.7
    morpholine-4-carbaldehyde 37.01
    sulfolane 49.09
    2,2,4-trimethylpentane 0.39
    2-methyltetrahydrofuran 26.03
    n-hexyl acetate 9.6
    isooctane 0.28
    2-(2-butoxyethoxy)ethanol 23.9
    sec-butyl acetate 9.46
    tert-butyl acetate 18.1
    decalin 0.68
    glycerin 8.87
    diglyme 62.02
    acrylic acid 11.38
    isopropyl myristate 6.44
    n-butyric acid 10.44
    acetyl acetate 22.85
    di(2-ethylhexyl) phthalate 6.72
    ethyl propionate 13.83
    nitromethane 64.25
    1,2-diethoxyethane 24.7
    benzonitrile 12.32
    trioctyl phosphate 4.3
    1-bromopropane 7.58
    gamma-valerolactone 44.96
    n-decanol 3.34
    triethyl phosphate 10.27
    4-methyl-2-pentanol 3.09
    propionitrile 12.55
    vinylene carbonate 15.88
    1,1,2-trichlorotrifluoroethane 37.14
    DMS 16.54
    cumene 3.03
    2-octanol 2.69
    2-hexanone 10.81
    octyl acetate 7.07
    limonene 4.99
    1,2-dimethoxyethane 48.25
    ethyl orthosilicate 9.8
    tributyl phosphate 5.94
    diacetone alcohol 18.8
    N,N-dimethylaniline 9.87
    acrylonitrile 20.65
    aniline 11.08
    1,3-propanediol 7.47
    bromobenzene 9.69
    dibromomethane 20.02
    1,1,2,2-tetrachloroethane 37.85
    2-methyl-cyclohexyl acetate 11.98
    tetrabutyl urea 9.33
    diisobutyl methanol 4.09
    2-phenylethanol 10.18
    styrene 4.95
    dioctyl adipate 11.85
    dimethyl sulfate 29.54
    ethyl butyrate 11.96
    methyl lactate 11.42
    butyl lactate 6.47
    diethyl carbonate 10.52
    propanediol butyl ether 7.88
    triethyl orthoformate 11.96
    p-tert-butyltoluene 3.93
    methyl 4-tert-butylbenzoate 17.18
    morpholine 36.07
    tert-butylamine 3.61
    n-dodecanol 2.84
    dimethoxymethane 43.37
    ethylene carbonate 13.12
    cyrene 20.97
    2-ethoxyethyl acetate 19.48
    2-ethylhexyl acetate 7.42
    1,2,4-trichlorobenzene 15.27
    4-methylpyridine 16.74
    dibutyl ether 8.04
    2,6-dimethyl-4-heptanol 4.09
    DEF 18.81
    dimethyl isosorbide 43.51
    tetrachloroethylene 22.4
    eugenol 16.55
    triacetin 21.75
    span 80 11.2
    1,4-butanediol 3.43
    1,1-dichloroethane 14.05
    2-methyl-1-pentanol 4.66
    methyl formate 12.85
    2-methyl-1-butanol 3.85
    n-decane 0.81
    butyronitrile 7.83
    3,7-dimethyl-1-octanol 4.35
    1-chlorooctane 2.98
    1-chlorotetradecane 1.59
    n-nonane 0.63
    undecane 0.6
    tert-butylcyclohexane 0.57
    cyclooctane 0.42
    cyclopentanol 7.45
    tetrahydropyran 23.77
    tert-amyl methyl ether 8.46
    2,5,8-trioxanonane 47.64
    1-hexene 1.37
    2-isopropoxyethanol 16.43
    2,2,2-trifluoroethanol 9.8
    methyl butyrate 13.64

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction